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3221
Sex-Related Differences in Immune Response and Symptomatic Manifestations to Infection with Leishmania Species
Published 2019-01-01“…The limitations of current therapies and the emergence of drug-resistant parasites underscore the need for new treatments that could harness the host immune response. …”
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3222
Specificity of Cognitive Impairment in Neurological Disease: A Methodological Critique of Parkinson’s Disease
Published 1991-01-01“…This critique presents some methodological issues relevant to the study of brain-behaviour and drug-behaviour relationships in syndromes of multiple cognitive deficit, using Parkinson's disease as the model. …”
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3223
A Photochromic Copolymer Hydrogel Contact Lens: From Synthesis to Application
Published 2016-01-01“…In addition, salicylic acid as a drug model could be loaded into hydrogel by immersing method, and its sustained drug release in a given period was dependent on the characteristics of solution and loading time.…”
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3224
Functionalized Selenium Nanoparticles Enhance Anticancer Efficacy of Doxorubicin for Hepatocellular Carcinoma Therapy
Published 2022-01-01“…Tumor-targeted selenium nanoparticles (HA-SeNPs) were prepared to load an anticancer drug doxorubicin (DOX). In this drug delivery system, hyaluronic acid (HA) was used as a tumor-targeted moiety to bind with its receptor highly expressed in hepatocellular carcinoma cells. …”
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3225
Assessment of Antiretroviral Treatment Adherence among Children Attending Care at a Tertiary Hospital in Southeastern Nigeria
Published 2017-01-01“…Our aim was to assess the antiretroviral drugs adherence status of HIV-infected children attending care at a tertiary hospital in Southeastern Nigeria. …”
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3226
Neurocranial Pharmacodialysis Device for subarachnoid hemorrhage treatment—a perspective
Published 2024-02-01“…This neuroengineered system, implantable in the neurocranium, can perform subarachnoid drug delivery, edema drainage, neurotoxin dialysis, and electroencephalography (EEG) recording for years, hence its therapeutic potential in SAH as a Neurocranial Pharmacodialysis Device (NPD). …”
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3227
Synthesis, Characterization, and Cytotoxic Evaluation of Some Newly Substituted Diazene Candidates
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3228
Evaluation of the Cytotoxic Effects of CAM Therapies: An In Vitro Study in Normal Kidney Cell Lines
Published 2014-01-01“…The major drawback of anticancer drugs is their nonselective killing, which ultimately leads to attrition of normal cells. …”
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3229
Some variables affecting the characteristics of Eudragit E-sodium alginate polyelectrolyte complex as a tablet matrix for diltiazem hydrochloride
Published 2014-03-01“…Tablets were evaluated for swelling characteristics and in vitro drug release. Tablets containing EE-SAH physical mixtures of ratios (1.5:1 and 1:3) as matrices were effective in achieving sustained release of DTZ HCl, where the percent drug released was significantly (p < 0.05) decreased compared to that from tablets either containing the same ratios of EE-SAL physical mixtures or the preformed EE- -SAH and EE-SAL PECs.…”
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3230
Chromatographic Characterization and Method Development for Determination of Levetiracetam in Saliva: Application to Correlation with Plasma Levels
Published 2017-01-01“…Levetiracetam (LVT) is a widely used antiepileptic drug (AED). A less invasive sampling method for therapeutic drug monitoring (TDM) would be very useful particularly for children. …”
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3231
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3232
Punicalagin attenuated allergic airway inflammation via regulating IL4/IL-4Rα/STAT6 and Notch- GATA3 pathways
Published 2022-12-01“…The data obtained illustrate the potency of punicalagin as an anti-asthmatic drug. Conclusively, the study’s observations suggest the potential therapeutic efficiency of punicalagin in allergic asthma.…”
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3233
Feedback control of an HBV model based on ensemble kalman filter and differential evolution
Published 2018-05-01“…In this paper, we derive efficient drug treatment strategies for hepatitis B virus (HBV) infection by formulating a feedback control problem. …”
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3234
Levofloxacin-Induced Acute Hyperpigmentation Changes in a Chronic Kidney Disease Patient
Published 2020-01-01“…Medication-induced cutaneous hyperpigmentation has variable clinical presentations and is dependent on the specific drug involved. Most commonly, an attentive patient observes such changes early in the course; when missed by the patient, such changes are usually noted by an observant clinician. …”
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3235
Development and Validation of an Extractive Spectrophotometric Method for Miconazole Nitrate Assay in Pharmaceutical Formulations
Published 2018-01-01“…The method is based on the formation of a chloroform-soluble ion-pair complex between the drug and bromocresol green (BCG) dye in an acidic medium. …”
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3236
Development and optimization of the activated charcoal suspension composition based on a mixture design approach
Published 2015-03-01“…In this study, a new drug product containing activated charcoal was designed and developed. …”
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3237
Tocilizumab-Induced Acute Liver Injury in Adult Onset Still’s Disease
Published 2013-01-01“…Liver biopsy showed extensive hepatocellular necrosis with ballooned hepatocytes, highly suggestive of drug-induced liver injury. No other relevant drug exposure beside tocilizumab was recorded. …”
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3238
Investigation on the Binding and Conformational Change of All-trans-Retinoic Acid with Peptidyl Prolyl cis/trans Isomerase Pin1 Using Spectroscopic and Computational Techniques
Published 2021-01-01“…All in all, the present research might provide a reference for the development and design of retinoic acid drugs that inhibit the activity of Pin1.…”
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3239
Liver Protective Effect of Fenofibrate in NASH/NAFLD Animal Models
Published 2022-01-01“…Fenofibrate is a fibrate drug approved for dyslipidemia that could be used for modulation of hepatic fat accumulation, targeting peroxisome proliferator-activator receptors, and de novo lipogenesis. …”
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3240
Dual Antiplatelet Therapy Regimens and Duration for Intracranial Stenting Procedures: Literature Review
Published 2023-11-01“…Our aim was to analyse different antithrombotic drug regimens and duration in intracranial stenting procedures (stent assisted coiling, flow diverter) for unruptured aneurysms and based on the literature review from 2017–2023 to implement dual antiplatelet therapy algorithm for neuro-interventional procedures in Lithuania. …”
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