Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case Report by A. Dalbeni, E. Capoferro, L. Bernardoni, P. Capelli, A. Caliò, A. Gabbrielli, F. Capra

“…Ischemic colitis is a serious drug-induced adverse event. There are only few cases of immunosuppression-associated ischemic colitis described in the literature, but none with a pancolitis-like manifestation. …”
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Therapeutic Applicability of Anti-Inflammatory and Proresolving Polyunsaturated Fatty Acid-Derived Lipid Mediators by Gerard L. Bannenberg

“…The anti-inflammatory drug aspirin is a striking example of a drug that is able to act in such a manner, namely through triggering the formation of 15-epi-lipoxin A4 and aspirin-triggered resolvins. …”
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Botulinum Neurotoxin Application to the Severed Femoral Nerve Modulates Spinal Synaptic Responses to Axotomy and Enhances Motor Recovery in Rats by Marcel Irintchev, Orlando Guntinas-Lichius, Andrey Irintchev

“…We applied drug solutions to the proximal stump of the freshly cut femoral nerve of adult rats to achieve drug uptake and transport to the neuronal perikarya. …”
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Pramipexole Extended Release: A Novel Treatment Option in Parkinson's Disease by Wolfram Eisenreich, Bernd Sommer, Sebastian Hartter, Wolfgang H. Jost

“…Pramipexole, the most commonly prescribed dopamine agonist worldwide, meanwhile serves as a reference substance for evaluation of new drugs. Based on numerous clinical data and vast experiences, efficacy and safety profiles of this non-ergoline dopamine agonist are well characterized. …”
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Retinal and Corneal Toxicity and Pharmacokinetic Analysis of Intraocular Injection of Ganciclovir in Rabbit Eyes by Bin-jia Sun, Rong-mei Peng, Qing Lu, Jing Hong

“…Intracameral injection results in rapid drug elimination and severe damage to endothelium and thus is not recommended.…”
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Recurrence of acne after treatment with systemic isotretinoin: causes and methods of prevention by Marina M. Tlish, Marina E. Shavilova

“…Isotretinoin is an effective drug for the treatment of patients with severe forms of acne, which has been proven in a large number of studies and is enshrined in the clinical recommendations of dermatological communities in various countries. …”
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Current Trends in Treatment for Acid-Dependent Diseases: Clinical Efficacy and Safety of Rabeprazole by O. D. Lopina, B. K. Nurgalieva, T. L. Lapina

“…This makes rabeprazole (Pariet) a preferred drug in course and maintenance therapies for acid-dependent diseases, as well as in H. pylori eradication.Conclusion. …”
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A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing by Shih-Feng Chou, Simi Gunaseelan, Mhd Hussam Hijazi Kiellani, Venkata Vamsi Krishna Thottempudi, Pierre Neuenschwander, Huarong Nie

“…The two major topics concerning the development of nanomedicine are drug delivery and tissue engineering. With the advance in nanotechnology, scientists and engineers now have the ability to fabricate functional drug carriers and/or biomaterials that deliver and release drugs locally as well as promote tissue regeneration. …”
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Acoustic bubbles: Inducing cell interactions via trapping, patterning, and removal by Jonathan Faulkner, Mengren Wu, Madelyn Wicker, Yuan Gao

“…Studying cell-cell interactions is crucial for understanding biological processes and advancing drug development. Recent advancements in microfluidic technology allow cell-cell interaction experiments to be performed on-chip, enabling the study of specific interactions within a highly defined microenvironment. …”
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Anticonvulsant valproic acid and other short-chain fatty acids as novel anticancer therapeutics: Possibilities and challenges by Lipska Katarzyna, Gumieniczek Anna, Filip Agata A.

“…Results from numerous pre-clinical studies suggest that a well known anticonvulsant drug valproic acid (VPA) and other short-chain fatty acids (SCFAs) cause significant inhibition of cancer cell proliferation by modulating multiple signaling pathways. …”
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Prevalence and Antibiotic Resistance Pattern of Salmonella Isolated from Caecal Contents of Exotic Chicken in Debre Zeit and Modjo, Ethiopia by Destaw Asfaw Ali, Belege Tadesse, Aragaw Ebabu

“…Of the 50 isolates, 48 were resistant to at least one drug. Multidrug resistance was recorded in 43 (86.0%) of the isolates. …”
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Molecular Docking, Dynamics Simulations, ADMET, and DFT Calculations: Combined In Silico Approach to Screen Natural Inhibitors of 3CL and PL Proteases of SARS-CoV-2 by Sugumar Mohanasundaram, Porkodi Karthikeyan, Venkatesan Sampath, M. Anbazhagan, Sundramurthy Venkatesa Prabhu, Jamal M. Khaled, Muthu Thiruvengadam

“…Considering natural compounds for the antiviral effect is another opportunity for exploring novel drug candidates for severe acute respiratory syndrome coronavirus 2. …”
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Disperse Solid-Phase Extraction Cleanup for the Determination of 1-Deoxynojirimycin in Mulberry Leaves with Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry by Lei Zhang, Yiran Zhou, Jing Meng, Jia Li

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Multi-assay assessment of cytotoxicity reveals multiple mechanisms of action in 3D microtissues by Ahbid Zein-Sabatto, Katerina St. Angelo, Samantha J. Madnick, Diane Hoffman-Kim, Jeffrey R. Morgan, Jonghwan Lee

“…Abstract Cell viability assays are an integral component of toxicology and high-throughput drug screening studies; however, many assays rely on a single biomarker of cell death which provides an incomplete assessment of cell viability. …”
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Cutaneous Necrotizing Vasculitis and Leukopenia in a Cocaine User: Is Levamisole the Culprit? by Lara El Khoury, Nabil Zeineddine, Richard Felix, Mark Goldstein

“…Levamisole is an antihelminthic drug banned by the US Food and Drug Administration (FDA) in 2000 because of its dangerous side effects. …”
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Effect of Ranirestat, a New Aldose Reductase Inhibitor, on Diabetic Retinopathy in SDT Rats by Fumihiko Toyoda, Yoshiaki Tanaka, Ayumi Ota, Machiko Shimmura, Nozomi Kinoshita, Hiroko Takano, Takafumi Matsumoto, Junichi Tsuji, Akihiro Kakehashi

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Navigating the potential and pitfalls of large language models in patient-centered medication guidance and self-decision support by Serhat Aydin, Mert Karabacak, Victoria Vlachos, Konstantinos Margetis

“…However, significant challenges exist, including the risk of misinformation and the complexity of providing accurate drug information without access to individual patient data. …”
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Macrophage-Based Therapies for Atherosclerosis Management by Renyi Peng, Hao Ji, Libo Jin, Sue Lin, Yijiang Huang, Ke Xu, Qinsi Yang, Da Sun, Wei Wu

“…In this review, we focused on the systematical summary of the macrophage-based therapies in AS management, including macrophage autophagy, polarization, targeted delivery, microenvironment-triggered drug release, and macrophage- or macrophage membrane-based drug carrier. …”
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ClpB chaperone as a promising target for antimicrobial therapy: A narrative review by Sachini J. Udari, Sayoka Shamodhi, Rumesh M. Nelumdeniya, Udayana Ranatunga, Nimesha N. Senadeera, Chathuranga B. Ranaweera

“…Infections caused by ESKAPE pathogens are particularly challenging due to their resistance to broad-spectrum antibiotics and biofilm formation, posing a significant global health threat as they are often multidrug-resistant, extensively drug-resistant, and pan-drug-resistant. Given its absence in human cells and its essential role in bacterial survival under stress, ClpB is a promising target for antimicrobial therapy. …”
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Osteogenic Differentiation of Mesenchymal Stem Cells via Curcumin-Containing Nanoscaffolds by Khadijeh Khezri, Solmaz Maleki Dizaj, Yalda Rahbar Saadat, Simin Sharifi, Shahriar Shahi, Elham Ahmadian, Aziz Eftekhari, Elaheh Dalir Abdolahinia, Farzaneh Lotfipour

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