Functional Dyspepsia and Gastroesophageal Reflux Disease: From Pathogenesis to Current Treatment Strategies by A. S. Trukhmanov, D. E. Rumyantseva

“…Currently, acotiamide is recognized as an effective drug that affects the motility of the upper gastrointestinal tract. …”
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An Unexpected Interaction between Sofosbuvir/Ledipasvir and Atorvastatin and Colchicine Causing Rhabdomyolysis in a Patient with Impaired Renal Function by Shyam Patel, Jennifer Andres, Kamran Qureshi

“…There is no mention of such HMG-CoA reductase inhibitor interaction as a class, as pravastatin did not have any clinically significant interaction with Sof/Led. Other myotoxic drugs, including colchicine are not studied. We present a case of a serious drug interaction between Sof/Led and atorvastatin, in the background of CKD and colchicine use.…”
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Development of Bioadhesive Microspheres for Oral Bioavailability Enhancement of Berberine Hydrochloride by Ye Zhang, Hongming Liu

“…The mean particle size of microspheres was 368.2 μm, drug loading was 3.59±0.01%, and in situ bioadhesion percentage was 91.23%±8.2% and they achieved a sustained release with 71.29% for 8 hours in vitro. …”
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Impact of <i>Saccharomyces cerevisiae</i> DSM 34246 (Canobios-BL) var. <i>boulardii</i> Supplementation on Nutritional Status and Fecal Parameters in Healthy Breeding Adult Cats by Nicolò Lonigro, Elisa Martello, Natascia Bruni, Mauro Bigliati, Annalisa Costale, Ilaria Lippi, Giorgia Meineri, Francesca Perondi

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Pathogenetic aspects and modern possibilities of therapy of vulvovaginal candidiasis by Margarita R. Rakhmatulina, Elena V. Lipova, Viktoria A. Nyanenko

“…The modern possibilities of drug therapy for vulvovaginal candidiasis, presented in domestic and foreign clinical recommendations, are discussed. …”
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Use of Rituximab in Autoimmune Hemolytic Anemia Associated with Non-Hodgkin Lymphomas by Claudio Fozza, Maurizio Longinotti

“…We will then analyze some studies focusing on rituximab in primary AHA, finally reviewing the available literature on the use of this drug in NHL related AHA.…”
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Intestinal inflammation in TNBS sensitized rats as a model of chronic inflammatory bowel disease by N. Selve, T. Wöhrmann

“…The applicability and relevance of this new model are discussed with respect to drug development and basic research of inflammatory bowel diseases.…”
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Estimation of Heavy Metals in Multivitamin Tablets by Differential Pulse Anodic Stripping Voltammetry by Kumar Rohit Raj, Shashank Sharma, Sachin Saxena, M. M. Srivastava, Soami P. Satsangi

“…Concentrations of zinc and copper in supradyn drug sample were found to be 1.80 and 2.9 mg/tablet and for centrum drug sample were found to be 4.6 and 0.94 mg/tablet respectively.…”
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Controlled Release of Ibuprofen by Using Morphologically Modified Mesoporous Silica by Sana Ahmad, Javariah Javaid, Wajeeha Fatima

“…The synthesis of mesoporous silica with variable pore sizes was carried out for the purpose of controlled drug release study. Mesoporous silica containing three-dimensional cagelike structures was prepared by the simple hydrothermal method using triblock copolymer Pluronic F-127 as the template and tetraethyl orthosilicate (TEOS) as a silica source. …”
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Exploring the genomic and antimicrobial resistance tapestry: comparative insights into Salmonella enterica serotypes Agona, Braenderup, Muenchen, and Panama in Latin American surfa... by Zhao Chen, Enrique J. Delgado Suárez, Raquel R. Bonelli, Celso J. B. Oliveira, Andrea I. Moreno-Switt, Aiko D. Adell, Angélica Reyes-Jara, Christopher J. Grim, Marc W. Allard, Sandra M. Tallent, Eric W. Brown, Rebecca L. Bell, Magaly Toro, Jianghong Meng

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Utilization of patient-reported outcomes to assess adherence to relugolix when combined with stereotactic body radiation therapy for intermediate to high-risk prostate cancer by Kelly Gaudian, Min Jung Koh, Min Ji Koh, Ryan R. Collins, Shaine Eden, Zoya Zwart, Malika Danner, Alan Zwart, Mark Fallick, Deepak Kumar, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

“…Overall patient-reported drug adherence was 75%. No patient demographic or clinical characteristic predicted non-adherence.DiscussionRelugolix allows for high rates of castration and drug adherence when combined with prostate SBRT. …”
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Identification of Adulterated Deer Blood Crystals in Traditional Chinese Medicine Based on MALDI-TOF MS Peptide Fingerprints Technique by Shen-xing WANG, Ling CAO, Qing HUANG, Cong-yu MA, Jian-bin PAN, Hao-dong ZHAO, Hai-wei SHI, Bin DI, Hong-yuan CHEN

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The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network by Yi Wang, Yi Wang, Moran Xu, Xiaoli Zuo, Sheng Wang, Yong Yu, Zhaobing Gao, Zhaobing Gao, Jingbo Qie, Ye Jiang, Fang Huang, Bingqing Xia, Bingqing Xia

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Coronil effectively inhibits the interaction of clinically relevant Omicron mutants of SARS-CoV-2 spike proteins with human ACE2 receptor by Acharya Balkrishna, Rishabh Dev, Sandeep Kumar, Anurag Varshney

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Computer-guided identification of novel inhibitors of apoptosis-signaling kinase 1 from Spondia mombim bioactive compounds against colorectal cancer by Olusola Olalekan Elekofehinti, Hannah Oluwaseun Popoola, Adedotun Olayemi Oluwatuyi, Opeyemi Iwaloye, Moses Orimoloye Akinjiyan, Oluwamodupe Cecilia, Frank Abimbola Ogundolie, Olalekan Isaac Olatunde, Oussama Abchir, Samir Chtita, Joao Batista Texeira Rocha

“…It mediates inflammation and apoptosis and promotes cell proliferation through the transcription of cyclin D1. 5-Fluorouracil remains one of the primary recommended drugs to manage colorectal cancer. However, this drug often causes various adverse effects, notably diarrhea, vomiting, nausea, and leukopenia. …”
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Antimycobacterial Activity, Synergism, and Mechanism of Action Evaluation of Novel Polycyclic Amines against Mycobacterium tuberculosis by Erika Kapp, Jacques Joubert, Samantha L. Sampson, Digby F. Warner, Ronnett Seldon, Audrey Jordaan, Margaretha de Vos, Rajan Sharma, Sarel F. Malan

“…Insufficient intracellular accumulation of active moieties allows for selective survival of mycobacteria with drug resistance mutations and accordingly promotes the development of microbial drug resistance. …”
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Antibacterial and Antifungal Activities of Linear and Cyclic Peptides Containing Arginine, Tryptophan, and Diphenylalanine by David Salehi, Eman H. M. Mohammed, Naiera M. Helmy, Keykavous Parang

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Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives by Dagmawi Woldesenbet, Yalewayker Tegegne, Abdulhakim Mussema, Elias Tamene, Kemal Mohamed, Wagaw Abebe, Melese Mekuria, Kasahun Bogale, Habtamu Geremew, Mufta Muzemil Shifa, Mulugeta Aemero Tegegne

“…However, challenges persist, including the emergence of drug and insecticide resistance, compounded by environmental and demographic factors. …”
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Novel Regulatory Mechanisms of Pathogenicity and Virulence to Combat MDR in Candida albicans by Saif Hameed, Zeeshan Fatima

“…Continuous deployment of antifungals in treating infections caused by dimorphic opportunistic pathogen Candida albicans has led to the emergence of drug resistance resulting in cross-resistance to many unrelated drugs, a phenomenon termed multidrug resistance (MDR). …”
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Quality of Life Assessment in Primary Headache Patients with Headaches Related to Abuse Using Scales and Questionnaires by Saidvaliyev Farrukh, Rakhimova Shakhnozakhon

“…Both groups showed moderate drug dependence, with higher levels in TTH patients. …”
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