A Novel Insight into Paraptosis-Related Classification and Signature in Lower-Grade Gliomas by Xi-Feng Qian, Jia-Hao Zhang, Yue-Xue Mai, Xin Yin, Yu-Bin Zheng, Zi-Yuan Yu, Guo-Dong Zhu, Xu-Guang Guo

“…We also confirmed the potential relationship of 10-PRG signatures and drug sensitivity of Food and Drug Administration–approved drugs. …”
Get full text

Analysis of Method Performance for Quantitative Assessment of Listeria monocytogenes in Queso Fresco Cheese by Neha Singh, Ravinder Reddy, Karina Hettwer, Kirstin Frost, Matthew Kmet, Steffen Uhlig

Get full text

Rapid Screening and Estimation of Binding Constants for Interactions of Fe3+ with Two Metalloproteins, Apotransferrin and Transferrin, Using Affinity Mode of Capillary Electrophore... by Mohammed Al Bratty, Hassan A. Alhazmi, Sadique A. Javed, Zia Ur Rehman, Asim Najmi, Karam A. El-Sharkawy

“…The present study may be used as a reference for the investigation of protein-metal ion, drug-protein, drug-metal ion, and enzyme-metal ion interactions and may be helpful to provide preliminary insight into the new metal-based drug development.…”
Get full text

Near-Infrared Spectroscopy during the Verbal Fluency Task before and after Treatment with Image Exposure and SSRI Therapy in Patients with Obsessive-Compulsive Disorder by Mari Nakanishi, Harumi Oshita, Yoshihiro Tanaka, Ayako Inoue, Chiwa Kawashima, Kana Okamoto, Shunsuke Kobayashi, Yoshinobu Ishitobi, Taiga Ninomiya, Jotaro Akiyoshi

“…Drug therapy with selective serotonin reuptake inhibitors (SSRIs) has been used as a treatment for obsessive-compulsive disorder (OCD). …”
Get full text

The role of HSPA14 in breast cancer: implications for tumorigenesis, immune response modulation, and personalized therapies by Ruipeng Zhao, Xiaocun Zhu, Wan Wei, Linlin Zhen

“…The data on HSPA14 levels and drug sensitivity were extracted from the CellMiner dataset. …”
Get full text

Network analyses of brain tumor multiomic data reveal pharmacological opportunities to alter cell state transitions by Brandon Bumbaca, Jonah R. Huggins, Marc R. Birtwistle, James M. Gallo

“…In addition to the lack of dedicated drug discovery programs for GBM, extensive intratumor heterogeneity and epigenetic plasticity related to cell-state transitions are major roadblocks to successful drug therapy in GBM. …”
Get full text

Computational antidiabetic assessment of Salvia splendens L. polyphenols: SMOTE, ADME, ProTox, docking, and molecular dynamic studies by Hatun A. Alomar, Wafaa M. El Kady, Asmaa A. Mandour, Amany A. Naim, Neveen I. Ghali, Taghreed A. Ibrahim, Noha Fathallah

“…This study utilizes artificial intelligence and machine learning to enhance drug discovery, focusing on the antidiabetic effects of Salvia splendens leaf extract among the global epidemic of diabetes mellitus. …”
Get full text

Anti-Malarial Effects of Five Traditional Nigerian Medicinal Plant Extracts on Plasmodium Berghei-Infected Rats by Ugochukwu Vincent, Igbokwe, Ejike, Daniel Eze, Moses Dele, Adams, Karimah Mohammed, Rabiu, Iliya, Ezekiel, Prisca Ojochogu, Ajeka, Peace Ogechukwu, Okpara

“…After 14 days of treatment, the extracts and drug exceptionally (p<0.05) reduced plasmodium count, WBC and ALP activity at all groups. …”
Get full text

Proteome selectivity profiling of photoaffinity probes derived from imidazopyrazine-kinase inhibitors by Dimitris Korovesis, Christel Mérillat, Rita Derua, Steven H. L. Verhelst

“…Abstract Kinases are attractive drug targets, but the design of highly selective kinase inhibitors remains challenging. …”
Get full text

Patient’s Own Medication Use During Hospitalization by Hamimatul Hayat Abdul Nasir, Jagjit Singh Dhaliwal, Hui Poh Goh, Long Chiau Ming, Daniel Vui Teck Wee, Khang Wen Goh, Ganesh Sritharan, Majid Ali, Yaman Walid Kassab

“…On the other hand, the efficacy of patient care was proven by reducing the frequency of medication error and prevalence of drug-drug interactions as the intervention was implemented. …”
Get full text

Perfluorocarbon Nanoparticles: Evolution of a Multimodality and Multifunctional Imaging Agent by Patrick M. Winter

“…In addition to these diagnostic imaging applications, the particles can be engineered to carry highly potent drugs and specifically deposit them into cell populations that display biosignatures of a variety of diseases. …”
Get full text

Exercise and Physical Activity in the Therapy of Substance Use Disorders by Elisabeth Zschucke, Andreas Heinz, Andreas Ströhle

“…The present work reviews studies addressing the therapeutic effects of exercise in alcohol abuse/dependence, nicotine abuse/dependence, and illicit drug abuse/dependence. In the field of smoking cessation, evidence is strong for exercise as an effective adjuvant treatment, whereas no generalizable and methodologically strong studies have been published for alcohol and drug treatment so far, allowing only preliminary conclusions about the effectiveness of exercise in these disorders. …”
Get full text

Head and Neck Squamous Cell Carcinoma: NT5E Could Be a Prognostic Biomarker by Yaoting Zhang, Sultan Kadasah, Jiaheng Xie, Dongsheng Gu

“…However, the emergence of drug resistance has brought difficulties to clinical treatment, and new immune checkpoint research is imminent. …”
Get full text

Putative Mechanism of Action of Trazodone-Related Oromandibular Dyskinesia by Alan L. Schneider

“…All cases showed abrupt cessation of the movement disorder when the drug was discontinued. One of the three cases demonstrated a highly unusual presentation of an on/off pattern of buccal dyskinesia directly related to repetitive exposure and termination of the drug trazodone. …”
Get full text

Essential oils – a review of the natural evolution of applications and some future perspectives by Stanislava Ivanova, Yana Gvozdeva, Radiana Staynova, Daniela Grekova-Kafalova, Vanya Nalbantova, Niko Benbassat, Nina Koleva, Kalin Ivanov

“…In the next decades it is highly likely that some compounds, isolated from EOs, could be included in the composition of novel drug candidates with targets in neurology, cardiology, or oncology. …”
Get full text

Cell-Specific Aptamers as Emerging Therapeutics by Cindy Meyer, Ulrich Hahn, Andrea Rentmeister

“…Their applications range from biosensing and diagnostics to therapy and target-oriented drug delivery. More recently, selections using complex targets such as live cells have become feasible. …”
Get full text

Amiodarone Pulmonary, Neuromuscular and Ophthalmologic Toxicity by Karen EA Burns, Eugenia Piliotis, Bertha M Garcia, Kathleen A Ferguson

“…The majority of adverse reactions resolve with discontinuation of the drug; however, rapid progression may occur, which may be fatal. …”
Get full text

Author Correction: Yindanxinnaotong, a Chinese compound medicine, synergistically attenuates atherosclerosis progress by Long Cheng, Guo-feng Pan, Xiao-dong Zhang, Jian-lu Wang, Wan-dan Wang, Jian-yong Zhang, Hui Wang, Ri-xin Liang, Xiao-bo Sun

Get full text

Time-resolved compositional and dynamics analysis of biofilm maturation and dispersal via solid-state NMR spectroscopy by Yi Xue, Xue Kang

Get full text

A RARE PRESENTATION OF MULTIPLE HYDATID CYSTON EITHER SIDE OF DIAPHRAGM by Rana Tabassum Ansari et al

“…The treatment was stopped at three months time with a 14 days drug-free period following which the treatment was restarted. …”
Get full text