Bioinformatics Based Drug Repurposing Approach for Breast and Gynecological Cancers: RECQL4/FAM13C Genes Address Common Hub Genes and Drugs by Gizem Ayna Duran

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A Challenge for Diagnosing Acute Liver Injury with Concomitant/Sequential Exposure to Multiple Drugs: Can Causality Assessment Scales Be Utilized to Identify the Offending Drug? by Roxanne Lim, Hassan Choudry, Kim Conner, Wikrom Karnsakul

“…Drug-induced hepatotoxicity most commonly manifests as an acute hepatitis syndrome and remains the leading cause of drug-induced death/mortality and the primary reason for withdrawal of drugs from the pharmaceutical market. …”
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Comparative drug-drug interactions of berberine and astragaloside IV in normal and type 2 diabetes mellitus rats based on UPLC-QqQ-MS/MS by Yan Lei, Jiaqi Xie, Zhongshui Xie, Xiaojun Zhao, Jianmei Huang, Can Wang

“…The gut microbiota was enriched in the intestines of T2DM rats and promoted the hydrolysis of AST to produce CAG, while the drug-drug interaction between AST and BBR was blocked.…”
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Peptide hydrogel-drug conjugates for tailored disease treatmentGuidelines to assemble peptide-based hydrogel-drug conjugates, referenced with a selection of relevant publications. by Thibault Cauwenbergh, Steven Ballet, Charlotte Martin

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Serum drug levels and anti-drug antibodies in the context of dose tapering by interval prolongation of adalimumab, etanercept and ustekinumab in psoriasis patients: results of the CONDOR trial by Selma Atalay, Sophie E. Berends, Hans M. M. Groenewoud, Ron A. A. Mathot, David M. Njoo, Johannes M. Mommers, Paul M. Ossenkoppele, Marjolein I. A. Koetsier, Maartje A. Berends, Annick de Vries, Peter C. M. van de Kerkhof, Alfons A. den Broeder, Elke M. G. J. de Jong, Juul M. P. A. van den Reek

“…However, fear for increased anti-drug antibody (ADA) formation due to interval prolongation of biologics is an important barrier.Objective To investigate the course of serum drug concentrations, ADA levels, and predictors for successful dose reduction of adalimumab, ustekinumab, and etanercept for psoriasis.Methods Patients were randomized to dose reduction (DR) or usual care (UC) and followed for one year. …”
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EGFR-targeting RNase A-cetuximab antibody-drug conjugate induces ROS-mediated apoptosis to overcome drug resistance in KRAS mutant cancer cells by Bita Jafary, Mostafa Akbarzadeh-Khiavi, Hamed Farzi-Khajeh, Azam Safary, Khosro Adibkia

Subjects: “…Antibody-drug conjugates (ADCs)…”
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Hyperuricemia, use of antituberculosis drugs, and liver injury: case report by Vina Yuwantari, Nur Oktafiyani, Nurmelinda Hadi Ningrum, M. Hari Pristantiningtyas, Herya Putra Dharma, Muhammad Muchlis, Jainuri Erik Pratama, Fauna Herawati, Adji Prayitno Setiadi, Marisca Evalina Gondokesumo

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Editorial: Advances in mitochondria-targeting in drug development for common disorders by Mundla Srilatha, Ganji Purnachandra Nagaraju

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Linking machine learning and biophysical structural features in drug discovery by Armin Ahmadi, Shivangi Gupta, Vineetha Menon, Jerome Baudry

Subjects: “…drug discovery…”
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Identifying Drug Prescription in Newly Diagnosed Hypertension Patients in India by Thomas Alexander, Jagdish S. Hiremath, Jitendra P. S. Swahney, Subhash Chandra, Peeyush Jain, Praveen Chandra, Nakul Sinha, T. Sashikanth, Yugandhar Bachhu, Anil Balachandran, Pathiyil Balagopalan Jayagopal, T. Govindan Unni, Tiny Nair, Kumaresan Kannan, Dorairaj Prabhakar, M. Chenniappan, Ajay U. Mahajan, Rajiv D. Karnik, Chandrashekhar K. Ponde, Prashant Advani, Idris Ahmed Khan, Brij Mohan Goyal, P. R. Vaidyanathan, Hiren Prajapati, Willem J. Verberk

“…ABSTRACT This study evaluated initial antihypertensive drug prescription patterns in Indian healthcare settings. …”
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A comprehensive review on roles of electrochemical approaches in drug delivery by Ali R. Jalalvand, Mohammad Mehdi Karami

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Nanotechnology-Based Drug Delivery Systems, 2nd Edition by Andrey N. Kuskov, Ekaterina V. Kukovyakina

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Eccentric indices based QSPR evaluation of drugs for schizophrenia treatment by Muneeba Mansha, Sarfraz Ahmad, Zahid Raza

“…Creating computational tools to find and develop drugs for schizophrenia has more interest in the past few years. …”
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Development, opportunities, and challenges of siRNA nucleic acid drugs by Bowen Xiao, Shaopeng Wang, Yu Pan, Wenjun Zhi, Chensheng Gu, Tao Guo, Jiaqi Zhai, Chenxu Li, Yong Q. Chen, Rong Wang

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Stapled peptides: targeting protein-protein interactions in drug development by Qian Zhang, Ziyang Wang, Xiaohan Mei, Quan Chen, Chunqiu Zhang

“…Exploration of Drug Science…”
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Real-World Experience with Dolutegravir-Based Two-Drug Regimens by Douglas Ward, Moti Ramgopal, David J. Riedel, Cindy Garris, Shelly Dhir, John Waller, Jenna Roberts, Katie Mycock, Alan Oglesby, Bonnie Collins, Megan Dominguez, James Pike, Joseph Mrus

“…Background. Dolutegravir-based 2-drug regimens (DTG 2DRs) are now accepted as alternatives to 3-drug regimens for HIV antiretroviral treatment (ART); however, literature on physician drivers for prescribing DTG 2DR is sparse. …”
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Editorial: Drug repurposing for cancer treatment: current and future directions by Marios Lampros, Nikolaos Vlachos, Georgios D. Lianos, Christina Bali, George A. Alexiou

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Doxorubicin-Conjugated Nanoparticles for Potential Use as Drug Delivery Systems by Alua Imantay, Nariman Mashurov, Balnur A. Zhaisanbayeva, Ellina A. Mun

Subjects: “…drug delivery…”
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PHARMACEUTICAL TECHNIQUES FOR THE FABRICATION OF POOR WATERSOLUBLE DRUGS A REVIEW by Rabia Noor

“… Pharmaceutical technologies for increasing the solubility of drug substances have a prime role in its faster dissolution and maximum absorption in the systemic circulation. …”
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Natural Products as Sources of Antimalarial Drugs: Ethnobotanical and Ethnopharmacological Studies by Oluwole Solomon Oladeji, Abimbola Peter Oluyori, Deborah Temitope Bankole, Tokunbo Yemisi Afolabi

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