Stability Studies of Thiocolchicoside in Bulk and Capsules Using RP-HPTLC/Densitometry by Dnyansing K. Rajput, Atul A. Shirkhedkar, Jyoti K. Rajput, Harun M. Patel, Sanjay J. Surana

“…The method can effectively separate the drug from its degradation products, and it can be considered as stability-indicating assay.…”
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Analgesic and Anti-inflammatory Activities of the Stem Bark of Yellow Flamboyant (<i>Peltophorum pterocarpum</i>) by O.K. Ogbeide, C.J. Ogbonnaya, E. Asakitikpi, D.O. Uyi, B.O. Aluge, O. Nosakhare, W.O. Otahagwa, C.A. Ehigie, U. Omoruyi, O.S. Aifuwa, B.O. Gabriel

“…Analgesic activity was investigated by using acetic acid-induced writhing model, using indomethacin as a reference drug. Antiinflammatory activity of n-hexane extract of P. pterocarpum stem bark was investigated by using formalin-induced paw licking model, using aspirin as standard drug. …”
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A Pair of Fluorescent Probes Enabling Precise Diagnosis of Liver Cancer by Complementary Imaging by Min Gao, Sun Hyeok Lee, Haw-Young Kwon, Larissa Miasiro Ciaramicoli, Eunsol Jo, Young Hyun Yu, Fengming Li, Beomsue Kim, Kyungtae Hong, Jun-Seok Lee, Namhui Kim, Yoojin Oh, Chun Young Im, Chris Soon Heng Tan, Hyung-Ho Ha, Young-Tae Chang

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Protocol for a scoping review study on the prevalence and public health consequences of non-medical use (NMU) of tramadol in Africa. by Saidou Sabi Boun, Olumuyiwa Omonaiye, Sanni Yaya, Sanni Yaya

“…<h4>Methods</h4>Due to the perceived lack of African literature on the subject, our search strategy is based on the simultaneous use of the keywords "tramadol" and Medical Subject Heading (MeSH), such as "Drug abuse," "illicit drugs," or "Prescription Drug Misuse," combined with the term "Africa" and Boolean operators (and, or not) to form our search equations. …”
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Update on Remdesivir in the Treatment of Novel Coronavirus Pneumonia by Huang Feng, K. Vijaya Lakshmi, Chin Tat Ng, Murthy Sasikumar, Masita Arip, Masriana Hassan, Voon Kin Chin, Mogana Rajagopal, Omotayo Fatokun, N. Parvathi, Malarvili Selvaraja

“…In this review, we summarized and reviewed the drug targets for COVID-19 management, especially the mechanism of action and research progress of Remdesivir. …”
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Preparation and In Vitro/In Vivo Evaluation of Vinpocetine Elementary Osmotic Pump System by Meiying Ning, Yue Zhou, Guojun Chen, Xingguo Mei

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A New Network-Based Strategy for Predicting the Potential miRNA-mRNA Interactions in Tumorigenesis by Jiwei Xue, Fanfan Xie, Junmei Xu, Yuan Liu, Yu Liang, Zhining Wen, Menglong Li

“…MicroRNA (miRNA) plays an important role in the degradation and inhibition of mRNAs and is a kind of essential drug targets for cancer therapy. To facilitate the clinical cancer research, we proposed a network-based strategy to identify the cancer-related miRNAs and to predict their targeted genes based on the gene expression profiles. …”
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Network Pharmacology Analysis of the Therapeutic Potential of Colchicine in Acute Lung Injury by Fei Sun, Lijuan Zhang, Lulu Shen, Chunman Wang

“…ALI-related genes were curated using databases such as DisGeNET, Therapeutic Target, and Comparative Toxicogenomics Database to curate ALI-related genes. Drug target fishing for colchicine was conducted using the DrugBank, BATMAN-TCM, STITCH, and SwissTargetPrediction. …”
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Postpartum-Isolated Native Pulmonic Valve Methicillin-Resistant Staphylococcus aureus Infective Endocarditis Complicated by Pelvic Abscess, Clavicle Osteomyelitis, and Polyarticula... by Daniela Navarrete, David Hannibal, Sachin M. Patil, Tarang Pankaj Patel, William Roland

“…The most commonly involved valves in injection drug users are the tricuspid valve followed by mitral and then aortic valves. …”
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Insights into the formulation properties, biocompatibility, and permeability of poorly water-soluble methoxyflavones with PEG400 and propylene glycol by Eze Fredrick Nwude, Jansakul Chaweewan, Srichana Teerapol

“…The TEER values of the Caco-2 cell monolayers indicated that the increased drug transport was partly due to increased tight junction openings, but without compromising the epithelial barrier integrity. …”
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Self-medication pattern among medical students in Middle Delta, Egypt by Nadira Mansour Hassan, Shimaa Mohamed Mohamed Koabar

“…Abstract Background Self- medication leading to wastage of limited resources in developing countries, prolonged suffering, increase resistance to drugs and may result in significant medical complications such as adverse drug responses and dependence. …”
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The impact of polypharmacy on health outcomes in the aged: A retrospective cohort study. by Irene Boateng, Carlos Rodriguez Pascual, Paul Grassby, Zahid Asghar, Kinda Ibrahim

“…<h4>Objectives</h4>To estimate the prevalence of polypharmacy among community-dwelling adults in the UK and determine its association with mortality, hospitalization, adverse drug reactions and falls at one and five years. To also determine the effect of polypharmacy on the outcomes in different patient groups.…”
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Synthesis, crystal structure and Hirshfeld surface analysis of 5,5-diphenyl-2-[2-(propan-2-ylidene)hydrazin-1-yl]-4,5-dihydro-1H-imidazol-4-one N,N-dimethylformamide hemisolvate by Abderrazzak El Moutaouakil Ala Allah, Benson M. Kariuki, Walid Guerrab, Abdulsalam Alsubari, Musa A. Said, Joel T. Mague, Youssef Ramli

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Clinical Impact of Sphingosine-1-Phosphate in Breast Cancer by Junko Tsuchida, Masayuki Nagahashi, Kazuaki Takabe, Toshifumi Wakai

“…It is difficult to cure the breast cancer patients with distant metastasis due to resistance to drug therapies. Elucidating the underlying mechanisms of breast cancer metastasis and drug resistance is expected to provide new therapeutic targets. …”
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The promising role of nanopore sequencing in cancer diagnostics and treatment by Xinming Su, Qingyuan Lin, Bin Liu, Chuntao Zhou, Liuyi Lu, Zihao Lin, Jiahua Si, Yuemin Ding, Shiwei Duan

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Model Prognosis Masa Pengobatan Pasien Tuberkulosis Dengan Metode C4.5 by Rusdah Rusdah, Brian Agni Bregastantyo

“…If a wrong diagnosis is related to drug dosage, it will increase health risk factors, namely where the treatment process will take more time and longer due to the Multi-Drug Resistant condition. …”
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A Convenient and Sensitive LC-MS/MS Method for Simultaneous Determination of Carbadox- and Olaquindox-Related Residues in Swine Muscle and Liver Tissues by Heying Zhang, Wei Qu, Yanfei Tao, Dongmei Chen, Shuyu Xie, Lingli Huang, Zhenli Liu, Yuanhu Pan, Zonghui Yuan

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Carboplatin-resistance-related DNA damage repair prognostic gene signature and its association with immune infiltration in breast cancer by Shuwen Dong, Anqi Li, Ruixin Pan, Jin Hong, Zheng Wang, Kunwei Shen

“…Immune infiltration analysis tools were employed to assess the immune microenvironment of patients with varying expression levels of these risk genes. Additionally, drug sensitivity predictions were made to evaluate the efficacy of other DNA damage-related drugs across different risk groups. …”
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A spatial model of tumor-host interaction: Application of chemotherapy by Peter Hinow, Philip Gerlee, Lisa J. McCawley, Vito Quaranta, Madalina Ciobanu, Shizhen Wang, Jason M. Graham, Bruce P. Ayati, Jonathan Claridge, Kristin R. Swanson, Mary Loveless, Alexander R. A. Anderson

“…The drug was treated as a diffusible substance entering the tissue from the blood vessels. …”
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Demographic disparities in access to COVID-19 clinical trial sites across the United States: a geospatial analysis by Raphael Cuomo, Tiana McMann, Qing Xu, Zhuoran Li, Joshua Yang, Julie Hsieh, Christine Lee, Milena Lolic, Richardae Araojo, Tim Mackey

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