Protease Inhibitor Resistance Is Uncommon in HIV-1 Subtype C Infected Patients on Failing Second-Line Lopinavir/r-Containing Antiretroviral Therapy in South Africa by Carole L. Wallis, John W. Mellors, Willem D. F. Venter, Ian Sanne, Wendy Stevens

“…Limited data exist on HIV-1 drug resistance patterns in South Africa following second-line protease-inhibitor containing regimen failure. …”
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Effects of new generation triptans – frovatriptan and almotriptan – on hemodynamic parameters in intact male and female rats by Saracheva Kremena, Hrischev Petar, Vasileva Liliya, Topolov Mariyan, Nikolova Julia, Getova Damianka

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Development of a new HPLC method for wogonin in rat plasma: Compatibility of standard and test samples by Salmani Jumah Masoud Mohammad, Wu Xue, Jacob Joe Antony, Fu Rong, Chen Baoan

“…Considerable attention was paid to the preparation of standard samples and factors affecting drug distribution. A preparation procedure was devised to simulate the conditions the drug is expected to experience in vivo while pointing to the shortcomings of previously published methods. …”
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Theoretical Calculations and Molecular Docking Analysis of 4-(2-(4-Bromophenyl)Hydrazineylidene)-3,5-Diphenyl-4H-Pyrazole Molecule by Ümit Yıldıko, Veysel Tahiroğlu, Mehmet Bağlan, Kenan Gören

“…Drug interactions involve combinations with drugs or other substances that change the effect of a drug on the body. …”
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Simultaneous Quantification of γ-Hydroxybutyrate, γ-Butyrolactone, and 1,4-Butanediol in Four Kinds of Beverages by Shaoming Jin, Xiao Ning, Jin Cao, Yaonan Wang

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Investigation of Antioxidant and Hepatoprotective Activity of Standardized Curcuma xanthorrhiza Rhizome in Carbon Tetrachloride-Induced Hepatic Damaged Rats by Sutha Devaraj, Sabariah Ismail, Surash Ramanathan, Mun Fei Yam

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Sample Aging Profoundly Reduces Monocyte Responses in Human Whole Blood Cultures by H. W. Grievink, M. Moerland

“…Human whole blood cultures are widely used for the investigation of physiological pathways and drug effects in vitro. Detailed information on the effect of “sample aging” (the time span between blood collection and experimental start) on the experimental outcome is not readily available in the public domain. …”
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Practice implications and recommendations for managing codeine misuse and dependence by Bergin Michael, Norman Ian, Foley Michelle, Harris Richard, Rapca Anna, Rich Eileen, Hout Marie-Claire Van

“…Evidence to inform law enforcement, drug surveillance, public health initiatives, harm reduction approaches, pharmacy, clinical and treatment practices is warranted.…”
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In Vitro and In Silico Analysis of Bergenia ciliata and Mimosa pudica for Inhibition of α-Amylase by Mahesh Bohara, Sajani Ghaju, Kabita Sharma, Surya Kant Kalauni, Karan Khadayat

“…The discovery of antidiabetic natural products is a flourishing field of opportunity in the sector of drug discovery. Various medicinal plants with diverse chemical constituents have been extensively studied for drug development. …”
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Isoferulic acid facilitates effective clearance of hypervirulent Klebsiella pneumoniae through targeting capsule. by Tingting Wang, Huaizhi Yang, Qiushuang Sheng, Ying Ding, Jian Zhang, Feng Chen, Jianfeng Wang, Lei Song, Xuming Deng

“…Hypervirulent Klebsiella pneumoniae (hvKP) poses an alarming threat in clinical settings and global public health owing to its high pathogenicity, epidemic success and rapid development of drug resistance, especially the emergence of carbapenem-resistant lineages (CR-hvKP). …”
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Crystal structure and anti-inflammatory activity of (E)-7-fluoro-2-((5-methoxypyridin-3-yl)methylene)-3,4-dihydronaphthalen-1(2H)-one, C17H14FNO2 by Sun Jia-Jia, Zhang Xiao-Fan, Meng Qing-Guo, Li Hong-Juan, Wang Chun-Hua

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Solubilization of ibuprofen for freeze dried parenteral dosage forms by Preskar Maja, Vrbanec Tomislav, Vrečer Franc, Šket Primož, Plavec Janez, Gašperlin Mirjana

“…Ibuprofen, a weakly acidic non-steroidal anti-inflammatory drug having poor aqueous solubility, is a challenging drug for the development of pharmaceutical formulations, resulting in numerous research attempts focusing on improvement of its solubility and consequently bioavailability. …”
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Diagnosis and Treatment of Childhood Pulmonary Tuberculosis: A Cross-Sectional Study of Practices among Paediatricians in Private Sector, Mumbai by Carolyn Kavita Tauro, Nilesh Chandrakant Gawde

“…Sputum negative TB suspect is always tested with X-ray or tuberculin skin test. 61.4% prescribe regimen as recommended in ISTC and all monitor progress to treatment clinically. Drug-resistance at beginning of treatment is suspected for child in contact with a drug-resistant patient (67.7%) and with prior history of antitubercular treatment (12.9%). …”
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Correction: Vertebral artery dissection in a patient with migraine treated with calcitonin gene-related peptide monoclonal antibody: a case report and FAERS database analysis by Daiki Tokuyasu, Shungo Imai, Shih-Pin Chen, Keiko Ihara, Narumi Watanabe, Yoshikane Izawa, Jin Nakahara, Satoko Hori, Tsubasa Takizawa

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Electric Field Analysis of Breast Tumor Cells by V. Gowri Sree, K. Udayakumar, R. Sundararajan

“…An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. …”
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"I'm Not Like Most of You Here, I'm Just an Alcoholic": A Russian Baptist Theory of Addiction by Igor Mikeshin

“…In my paper I discuss alcoholics in the Russian Baptist rehabilitation ministry by comparing them to drug addicts. In the outside world, as well as in the early stages of the rehabilitation program, alcoholics and illicit drug abusers are perceived as different cultural groups. …”
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Resveratrol as a potential broad-spectrum compound for cancer treatment by Li Kar Stella Tan, Chee Wun How, Jhi Biau Foo, Kooi Yeong Khaw, Bey Hing Goh, Yong Sze Ong

“…The severe adverse side effects, drug resistance and unaffordable price plagued with chemotherapeutic drugs has spurred the development of “dirty drug”. …”
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Modern options of application of domperidone in gastroenterology by A. A. Sheptulin

“…To carry out analysis of the publications devoted to application of prokinetic drug domperidone (D) at various gastroenterological diseases.Key points. …”
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Patient Care and Support Measures Overcome Reluctance to Initiate New Regimen Containing Enfuvirtide by Benoit Trottier

“…In the present patient, who showed resistance to all three of the major antiretroviral drug classes, enfuvirtide was successfully introduced with clinic and peer support group assistance. …”
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iDICss robustly predicts melanoma immunotherapy response by synergizing genomic and transcriptomic knowledge via independent component analysis by Jiayue Qiu, Nana Jin, Lixin Cheng, Chen Huang

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