Budget Impact Analysis of Darbepoetin Alfa Every 3 Weeks versus Epoetin Alfa Every Week for Cancer Patients with Anemia due to the Effect of Concomitant Myelosuppressive Chemothera... by November McGarvey, Hairong Xu

“…Annual average drug costs for administrations were estimated at $100 (DA) and $301 (EA) for 2014. …”
Get full text

Antitumor Necrosis Factor-Alpha (TNF-α) Infliximab-Induced Pleural Effusion and Pericarditis in Crohn’s Disease by Ashley Fonseca, Julee Sunny, Lina M. Felipez

“…However, some patients with CD can present severe adverse effects such as drug-induced lupus and rarely present with pleural space and pericardium involvement. …”
Get full text

Projecting the Potential Budget Impact Analysis of Paliperidone Palmitate in Egyptian Adult Patients with Schizophrenia by Gihan Elsisi, Mohamed Ezzat, Mohamed Ramadan

“…Direct medical costs and indirect costs were measured. The unit cost of drug acquisition for all medications was extracted from the public sector. …”
Get full text

Impact of Methods of Preparation on Mechanical Properties, Dissolution Behavior, and Tableting Characteristics of Ibuprofen-Loaded Amorphous Solid Dispersions by Ajam Uddin, Shimul Halder, Nandita Deb, Harinarayan Das, Madhabi Lata Shuma, Ikramul Hasan, Manik Chandra Shill, Syed Shabbir Haider

“…This study aims to improve the biopharmaceutical, mechanical, and tableting properties of a poorly soluble drug, ibuprofen (IBP), by preparing amorphous solid dispersion (ASD) followed by a sustained-release tablet formulation. …”
Get full text

Natural products based on Correa's cascade for the treatment of gastric cancer trilogy: Current status and future perspective by Wenhao Liao, Jing Wang, Yuchen Li

“…Natural products (NPs) have been an important source for drug development due to abundant sources, tremendous safety, and multiple pharmacodynamic mechanisms. …”
Get full text

Digestive Enzyme Inhibition of Different Phenolic Fractions and Main Phenolic Compounds of Ultra-High-Pressure-Treated Palm Fruits: Interaction and Molecular Docking Analyses by Qingfeng Zhou, Jiexin Zhou, Xiaojing Liu, Yan-Bing Zhang, Shengbao Cai

Get full text

Prevalence and methodologies for detection, characterization and subtyping of Listeria monocytogenes and L. ivanovii in foods and environmental sources by Jin-Qiang Chen, Patrick Regan, Pongpan Laksanalamai, Stephanie Healey, Zonglin Hu

Get full text

Quantitative Determination and Validation of Metformin Hydrochloride in Pharmaceutical Using Quantitative Nuclear Magnetic Resonance Spectroscopy by H. H. Gadape, K. S. Parikh

“…For the quantification of the drug, the (1H NMR signals at 2.91 ppm and 6.25 ppm corresponding to the analyte proton of metformin hydrochloride and maleic acid internal reference standard (IS) respectively were used. …”
Get full text

Faktor-Faktor yang Mempengaruhi Kepatuhan Minum Obat Pada Pasien Skizofrenia by Randy Refnandes, Zakiah Almaya

“…Treatment factors were the amount of drug, type of drug, side effects of the drug, severity of symptoms, and duration of treatment. …”
Get full text

Relapsing Malaria: A Case Report of Primaquine Resistance by Christopher Dijanic, Jillian Nickerson, Sunita Shakya, Amanda Dijanic, Marilyn Fabbri

“…We think of relapse occurring because of parasitic resistance or poor compliance secondary to drug toxicities. However, in patients with repeated treatment failure, we must consider CYP-450 mutations affecting drug metabolism as an important cause of relapse. …”
Get full text

Co-Amoxiclav Induced Immune Haemolytic Anaemia: A Case Report by H. G. C. S. Karunathilaka, D. P. Chandrasiri, P. Ranasinghe, V. Ratnamalala, A. H. N. Fernando

“…Drug-induced immune haemolytic anaemia (DIIHA) is extremely rare. …”
Get full text

Application of Surface Roughness Analysis on Micro–Computed Tomographic Images of Bone Erosion: Examples Using a Rodent Model of Rheumatoid Arthritis by Matthew D. Silva, Jason Ruan, Elizabeth Siebert, Anneli Savinainen, Bruce Jaffee, Lisa Schopf, Sudeep Chandra

“…The main advantage of such an algorithm is demonstrated in the preclinical drug study of rat CIA with methotrexate treatment, indicating the immediate utility of this approach in drug development studies.…”
Get full text

Pemilihan, Penyimpanan dan Stabilitas Sampel Toksikologi pada Korban Penyalahgunaan Narkotika by Citra Manela

“…<br />Keywords: sample, drug abused</p>…”
Get full text

New Possibilities for the Treatment of Crohn’s Disease by Z. A. Mamieva, E. A. Poluektova, O. S. Shifrin

“…The reviewed studies show Ustekinumab to be an effective and safe drug for the induction and the maintenance of clinical remission in patients with Crohn’s disease.…”
Get full text

Extractive Spectrophotometric Method for Determination of Pioglitazone Hydrochloride in Raw Material and Tablets Using Ion-Pair Formation by Massoud Amanlou, Mohadeseh Zarei-Ghobadi, Mohammad Kazem Rofouei, Shahrooz Saremi, Abbas Kebriaeezadeh

“…This method is based on the formation of yellow ion-pair complex between the basic nitrogen of the drug and bromocresol green (BCG) in phthalate buffer of pH 2.4. …”
Get full text

Novel Gallium(III), Germanium(IV), and Hafnium(IV) Folate Complexes and Their Spectroscopic, Thermal Decomposition, Morphological, and Biological Characteristics by Abeer A. El-Habeeb

“…The inhibition of four bacterial and two fungi pathogens (E. coli, B. subtilis, P. aeruginosa, S. aureus, A. flavus, and Candida albicans) was improved using a folic acid drug relative to the control drug.…”
Get full text

Acute Immune-Mediated Thrombocytopenia due to Oxaliplatin and Irinotecan Therapy by Eric L. Tam, Padma L. Draksharam, Jennifer A. Park, Gurinder S. Sidhu

“…Drug-induced thrombocytopenia (DITP) is associated with several classes of drugs with several proposed underlying mechanisms. …”
Get full text

A microscale thermophoresis-based enzymatic RNA methyltransferase assay enables the discovery of DNMT2 inhibitors by Zarina Nidoieva, Mark O. Sabin, Tristan Dewald, Annabelle C. Weldert, Sabrina N. Hoba, Mark Helm, Fabian Barthels

“…Abstract RNA methyltransferases (MTases) have recently become increasingly important in drug discovery. Yet, most frequently utilized RNA MTase assays are limited in their throughput and hamper this rapidly evolving field of medicinal chemistry. …”
Get full text

Ethical Issues in Pharmacologic Research in Women Undergoing Pregnancy Termination: A Systemic Review and Survey of Researchers by Christelle Gedeon, Alejandro A. Nava-Ocampo, Gideon Koren

“…The majority of participants believe that this form of research is necessary to furthering our understanding of drug use in pregnancy. Twenty studies were identified in women undergoing a pregnancy termination where exogenous drug was administered and drug measurement conducted during an abortion. …”
Get full text

Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients by Krista A. Delviks-Frankenberry, Chawaree Chaipan, Rachel Bagni, Kathleen Wyvill, Robert Yarchoan, Vinay K. Pathak

Get full text