Showing 2,701 - 2,720 results of 9,864 for search '"drug"', query time: 0.07s Refine Results
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    Identification of therapeutic target genes for age-related hearing loss through systematic genome-wide mendelian randomization of druggable genes by Kun Zhang, Bo Hou, Tao Yan, Ruru Qiao, Peng Qu, Xinbo Xu, Hanbing Zhang

    Published 2025-02-01
    “…Mendelian randomization (MR) has been used to repurpose existing drugs and identify new therapeutic targets. Therefore, we performed a systematic genome-wide MR of drug-eligible individuals to explore potential therapeutic targets for ARHL. …”
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  6. 2706

    Cyclophosphamide: An Overview by Aditya Kumar Bubna

    Published 2025-01-01
    “…Although not a first-line drug for any of the dermatological disorders, it has been found to be useful as a second-line drug in unresponsive cases. …”
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  7. 2707

    Clinical Outcome with Oral Linezolid and Rifampin Following Recurrent Methicillin-Resistant Staphylococcus aureus Bacteremia Despite Prolonged Vancomycin Treatment by Jon-David Schwalm, Philippe El-Helou, Christine H Lee

    Published 2004-01-01
    “…Drug-resistant Gram-positive bacteria, especially Staphylococcus aureus, are emerging as the predominant organisms involved in both nosocomial and community-acquired infections. …”
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    Gab Adapter Proteins as Therapeutic Targets for Hematologic Disease by Sheetal Verma, Tamisha Vaughan, Kevin D. Bunting

    Published 2012-01-01
    “…The multifunctionality of Gab adapters might suggest that they would be too difficult to consider as candidates for “targeted” therapy. However, the one drug/one target approach is giving way to the concept of one drug/multiple target approach since few cancers are addicted to a single signaling molecule for survival and combination drug therapies can be problematic. …”
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  9. 2709

    Outside-in engineering of cadherin endocytosis using a conformation strengthening antibody by Bin Xie, Shipeng Xu, Sanjeevi Sivasankar

    Published 2025-01-01
    “…We show that the anti-cancer drug delivery monoclonal antibody CQY684, traps P-cadherin in an X-dimer conformation and strengthens this adhesive structure. …”
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  10. 2710

    The Psych Behind Psychedelics: Exploring Hallucinogen Use as a Marker for Untreated Mental Health Disorders by Liyana Ahmed, Sanjana Konda, Latha Ganti

    Published 2025-01-01
    “…The positive correlation between hallucinogen use and other drug use indicates the widespread drug abuse problem, especially within a younger population in which drugs pose a larger neurological threat.…”
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    2-Amino-1,3,4-thiadiazoles as prospective agents in trypanosomiasis and other parasitoses by Serban Georgeta

    Published 2020-09-01
    “…Due to old medications and drug resistance worldwide, there is an urgent need for new antiparasitic drugs. 1,3,4-Thiadiazoles have been widely studied for medical applications. …”
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    Improving breast cancer treatments using pharmacomicrobiomics by Aswin Anand Pai, Aadra Prashant Bhatt

    Published 2025-02-01
    “…However, a significant proportion of patients experience disease recurrence due to treatment failure attributed to various factors, including disease pathology, genetics, and drug metabolism. Alam et al. introduce gut microbiota as a key factor influencing tamoxifen pharmacokinetics (Y. …”
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    Acute Liver and Renal Failure: A Rare Adverse Effect Exclusive to Intravenous form of Amiodarone by Robin Paudel, Prerna Dogra, Saurav Suman, Saurav Acharya, Jyoti Matta

    Published 2016-01-01
    “…Amiodarone is an antiarrhythmic drug which is highly effective against a wide spectrum of ventricular tachyarrhythmias making it irreplaceable in certain group of patients. …”
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    Marked Gingival Overgrowth Protruding from the Oral Cavity Due to Sodium Valproate by Mami Uegami, Hiroaki Ito, Tadashi Shiohama

    Published 2025-01-01
    “…Drug-induced gingival overgrowth is associated with various systemic diseases, including epilepsy. …”
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  18. 2718

    On the Temperature Indices of Molecular Structures of Some Networks by Akbar Jahanbani, Rana Khoeilar, Murat Cancan

    Published 2022-01-01
    “…Theoretical and statistical study of drug-like compounds improves the drug design and finding work-flow by rationalizing lead detection, instant decision, and mechanism of action comprehension. …”
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