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  1. 2661

    Efficacy of esomeprazole at treatment of patients with gastroesophageal reflux disease by Yu. V. Yevsyutina

    Published 2018-08-01
    “…Esomeprazole, in particular generic drug Emanera, is one of the most effective and safe antisecretory drugs. …”
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    Article
  2. 2662

    Timing of Antiretroviral Therapy for HIV in the Setting of TB Treatment by Damani A. Piggott, Petros C. Karakousis

    Published 2011-01-01
    “…However, concomitant administration of antiretroviral and antituberculous therapies poses significant challenges, including cumulative drug toxicities, drug-drug interactions, high pill burden, and the immune reconstitution inflammatory syndrome (IRIS), thus complicating the management of coinfected individuals. …”
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    Article
  3. 2663

    Catechin-Albumin Conjugates: Enhanced Antioxidant Capacity and Anticancer Effects by Tooru Ooya, Izumi Haraguchi

    Published 2022-01-01
    “…(+)-Catechin conjugated with human serum albumin (CT–HSA) was prepared and evaluated as a drug carrier bearing anticancer effects. It was found that 2.4 mol of CT was conjugate to 1 mol HSA. …”
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    Article
  4. 2664
  5. 2665

    Better Evidence and UpToDate Training Module 3: Additional UpToDate Functionality by Kabale University Library

    Published 2023
    “…This module explains Drug Database and Drug Interactions,How to use Clinical Calculators and Graphics and Algorithms…”
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  6. 2666

    Clinical Efficacy and Safety Analysis of Levofloxacin for the Prevention of Infection after Traumatic Osteoarthrosis and Internal Fixation: Systematic Review and Meta-Analysis by Weiliang Wang, ChuanQi Zou, Jie Zhang

    Published 2022-01-01
    “…Meanwhile, China ADR Information Bulletin and WHO Pharmaceutical were searched manually. Newsletter and FDA Drug Safety Newsletter, also to retrieve the Websites of Chinese, Chinese, and drug regulatory authorities; To obtain data on adverse events in children with systemic administration of levofloxacin. …”
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    Article
  7. 2667
  8. 2668

    Direct-Acting Antivirals for the Treatment of Chronic Hepatitis C: Open Issues and Future Perspectives by Hee Bok Chae, Seon Mee Park, Sei Jin Youn

    Published 2013-01-01
    “…Combination of drugs with different mechanisms shows a good sustained virological response (SVR). …”
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    Article
  9. 2669
  10. 2670

    QSPR Analysis of Some Alzheimer’s Compounds via Topological Indices and Regression Models by Muhammad Shoaib Sardar, Khalil Hadi Hakami

    Published 2024-01-01
    “…Topological indices and quantitative structure-property relationships (QSPRs) are indispensable in drug discovery. They allow researchers to analyze, compare, and predict the properties of chemical compounds, thereby expediting the identification of promising drug candidates while minimizing experimental costs and efforts. …”
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  11. 2671
  12. 2672
  13. 2673
  14. 2674

    L-Threonine-Derived Biodegradable Polyurethane Nanoparticles for Sustained Carboplatin Release by Seoeun Oh, Soo-Yong Park, Hyung Il Seo, Ildoo Chung

    Published 2024-12-01
    “…<b>Background and objectives:</b> The use of polymeric nanoparticles (NPs) in drug delivery systems offers the advantages of enhancing drug efficacy and minimizing side effects; <b>Methods:</b> In this study, L-threonine polyurethane (LTPU) NPs have been fabricated by water-in-oil-in-water emulsion and solvent evaporation using biodegradable and biocompatible LTPU. …”
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    Article
  15. 2675

    Antimicrobial Doses in Continuous Renal Replacement Therapy: A Comparison of Dosing Strategies by Anna P. Kempke, Abbie S. Leino, Farzad Daneshvar, John Andrew Lee, Bruce A. Mueller

    Published 2016-01-01
    “…Purpose. Drug dose recommendations are not well defined in patients undergoing continuous renal replacement therapy (CRRT) due to limited published data. …”
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    Article
  16. 2676

    Enhanced Expression of ABCB1 and Nrf2 in CD133-Positive Cancer Stem Cells Associates with Doxorubicin Resistance by Shinji Goto, Tsuyoshi Kawabata, Tao-Sheng Li

    Published 2020-01-01
    “…The precise mechanism about drug resistance of cancer stem cells (CSCs) has not yet been completely understood. …”
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    Article
  17. 2677

    Vaccines for cancer interception in familial adenomatous polyposis by David E. Johnson, Mary L. Disis

    Published 2025-01-01
    “…The lack of efficacy of more standard drug approaches may be due to limited exposure to the agent only to specific periods while the drug is being metabolized, limited drug penetrance in the colon, and patient adherence to daily dosing and drug side effects. …”
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    Article
  18. 2678
  19. 2679

    HOXB8 mediates resistance to cetuximab in colorectal cancer cells through activation of the STAT3 pathway by Yunan Liang, Han Lin, Zongsheng Jiang, Qi Zhao, Ri Cui, Shaotang Li

    Published 2024-10-01
    “…Currently, the role of HOXB8 in cetuximab-resistant mCRC remains unclear. By comparing drug-sensitive cell lines (SW48) with drug-resistant cell lines (HCT116, CACO2), we discovered that HOXB8 was substantially expressed in cetuximab-resistant cell lines, and furthermore, in drug-resistant cell lines (HCT116, CACO2), HOXB8 knockdown increased the cytotoxicity of cetuximab via blocking the signal transducer and activator of transcription 3 (STAT3) signaling pathway. …”
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    Article
  20. 2680