Injectable supramolecular hydrogel co-loading abemaciclib/NLG919 for neoadjuvant immunotherapy of triple-negative breast cancer by Binyu Zhu, Ying Cai, Lingli Zhou, Lei Zhao, Jiameng Chen, Xiaoting Shan, Xujie Sun, Qian You, Xiang Gong, Wen Zhang, Helen He Zhu, Pengcheng Zhang, Yaping Li

“…Herein, we create an abemaciclib-loaded supramolecular peptide hydrogel formed by peptide-drug amphiphiles for neoadjuvant immunotherapy of triple-negative breast cancer, where the amphiphile is a conjugate of a β-sheet-forming peptide with 1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol (NLG919), an inhibitor of indoleamine 2,3-dioxygenase 1. …”
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The Role of OCT Angiography in the Assessment of Epiretinal Macular Membrane by Daniela Bacherini, Francesco Dragotto, Tomaso Caporossi, Chiara Lenzetti, Lucia Finocchio, Alfonso Savastano, Maria Cristina Savastano, Francesco Barca, Martina Dragotto, Lorenzo Vannozzi, Francesco Nasini, Francesco Faraldi, Stanislao Rizzo, Gianni Virgili, Fabrizio Giansanti

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Analisis Asosiasi Untuk Menemukan Pola Pada Terapi Obat Pasien Dengan Menggunakan Metode Apriori by Evi Dewi Sri Mulyani, Teuku Mufizar, Sarmidi Sarmidi, Cepi Rahmat Hidayat, Dede Syahrul Anwar, Rofi Chaeruddin

“…Different drug therapies are given for diseases that have different symptoms, but the same drug therapy can be given to different diseases with the same symptoms. …”
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Rapid depletion of “catch-and-release” anti-ASGR1 antibody in vivo by Siva Charan Devanaboyina, Peng Li, Edward L. LaGory, Carrie Poon-Andersen, Kevin D. Cook, Marcus Soto, Zhe Wang, Khue Dang, Craig Uyeda, Ryan B. Case, Veena A. Thomas, Ronya Primack, Manuel Ponce, Mei Di, Brian Ouyang, Joelle Kaner, Sheung Kwan Lam, Mina Mostafavi

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Electrochemical Behavior of Biologically Important Indole Derivatives by Cigdem Karaaslan, Sibel Suzen

“…Voltammetric techniques are most suitable to investigate the redox properties of a new drug. Use of electrochemistry is an important approach in drug discovery and research as well as quality control, drug stability, and determination of physiological activity. …”
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Capture réglementaire en temps de pandémie by Samira Guennif

“…In the midst of the covid-19 pandemic, the Food and Drug Administration (FDA) published in March the orphan drug status granted to remdesivir, a molecule patented by Gilead as a treatment for the new coronavirus. …”
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Direct Comparison of 19F qNMR and 1H qNMR by Characterizing Atorvastatin Calcium Content by Yang Liu, Zhaoxia Liu, Huaxin Yang, Lan He

“…Quantitative nuclear magnetic resonance (qNMR) is a powerful tool in measuring drug content because of its high speed, sensitivity, and precision. …”
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Microencapsulation Techniques in HIV Pediatric Formulations: Advances and Future Outlook by Nnamdi Ikemefuna Okafor

“…Due to the dearth of clinically licensed pediatric antiretroviral drug (ARVD) therapy, children with HIV worldwide are prescribed unlicensed drugs each year. …”
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Adipokines and Hepatic Insulin Resistance by Yu Li, Lin Ding, Waseem Hassan, Daoud Abdelkader, Jing Shang

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Preparation and characterization of simvastatin/DMβCD complex and its pharmacokinetics in rats by Gu Fugen, Ning Jia, Fan Huimin, Wu Chunzhi, Wang Yi

“…Dissolution and pharmacokinetic studies indicated that the simvastatin/DMβCD complex exhibited an increased dissolution rate, rapid absorption, and improved bioavailability in rats compared to free drug. Maximum plasma concentration (cmax) and the time to reach it (tmax) were 21.86 μg mL−1 and 1.4 h for the drug complex, 8.25 μg mL−1 and 3.0 h for free drug, respectively. …”
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An Interactive Database of Cocaine-Responsive Gene Expression by Willard M. Freeman, Kathryn E. Dougherty, Sally E. Vacca, Kent E. Vrana

“…The postgenomic era of large-scale gene expression studies is inundating drug abuse researchers and many other scientists with findings related to gene expression. …”
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Preparation and Evaluation of Intravaginal Ring Containing Drospirenone by Ying Zhang, Chun-Xiao Li, Mei-Ying Ning, Xue-Yan Duan, Ying Liu

“…It is feasibility feasibile to further developed for safe, convenient, and effective contraceptive drug delivery with reduced dosing interval.…”
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Caffeic Acid Phenethyl Ester Regulates PPAR’s Levels in Stem Cells-Derived Adipocytes by Luca Vanella, Daniele Tibullo, Justyna Godos, Francesca Romana Pluchinotta, Claudia Di Giacomo, Valeria Sorrenti, Rosaria Acquaviva, Alessandra Russo, Giovanni Li Volti, Ignazio Barbagallo

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The Comorbidity of Depression and Diabetes Is Involved in the Decidual Protein Induced by Progesterone 1 (Depp1) Dysfunction in the Medial Prefrontal Cortex by Chen Xu, Mengxing Liao, Shize Zhang, Yuang Chen, Xinyue Shulai, Guangji Wang, Jiye Aa

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p97 Inhibitors Possessing Antiviral Activity Against SARS-CoV-2 and Low Cytotoxicity by Rui Ding, Tiffany C. Edwards, Prithwish Goswami, Daniel J. Wilson, Christine D. Dreis, Yihong Ye, Robert J. Geraghty, Liqiang Chen

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Study of Treatment in Heart Disease Patients Installation in Undata Hospital, Central Sulawesi by Niluh Puspita Dewi, Indah Kurnia Utami, Al'vira Gunawan, Muh. Thamrin Tahir, Syafika Alaydrus, Nani Astria Polontalo

“…The purposesof this study was to describe t he characteristics and use of heart disease drugs based on parameters of rationality of drug use in Undata Hospital, Central Sulawesi Province including gender, age, heart drug class, complementary drug class, length of hospitalization, laboratory data, comorbidities , appropriate indications, the right drugs and the right dose. …”
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Pomegranate Juices: Analytical and Bio-Toxicological Comparison of Pasteurization and High-Pressure Processing in the Development of Healthy Products by Francesco Cairone, Stefania Cesa, Irene Arpante, Simonetta Cristina Di Simone, Alejandro Han Mendez, Claudio Ferrante, Luigi Menghini, Antonello Filippi, Caterina Fraschetti, Gokhan Zengin, Simone Carradori, Marialucia Gallorini, Luisa Mannina, Mattia Spano

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Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway by Yingfu Chen, Burong Feng, Ye Yuan, Juan Hu, Wei Zhao, Huiwei Jiang, Wen Li, Ziyi Fan, Zhimin Du

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PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1 by Fei Xie, Han Zhang, Kongkai Zhu, Cheng‐Shi Jiang, Xiaoya Zhang, Hongkai Chang, Yaya Qiao, Mingming Sun, Jiyan Wang, Mukuo Wang, Junzhen Tan, Tao Wang, Lianmei Zhao, Yuan Zhang, Jianping Lin, Chunze Zhang, Shuangping Liu, Jianguo Zhao, Cheng Luo, Shuai Zhang, Changliang Shan

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Dipropyl phthalate induces craniofacial chondrogenic defects in zebrafish embryos by Qinyuan Shen, Weitao Hu, Fasheng Liu, Si Dong, Xinya Peng, Yihang Zhong, Chao Chen, Yuhua Zuo, Chenkai Ge, Weirong Li, Wenwen Zha, Zhijun Ye, Zigang Cao, Lan Liao

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