Exogenous dihomo-γ-linolenic acid triggers ferroptosis via ACSL4-mediated lipid metabolic reprogramming in acute myeloid leukemia cells by Xiandong Jiang, Yingying Huang, Xiaoying Hong, Wei Wu, Yanfeng Lin, Liping Lin, Yan Xue, Donghong Lin

“…This study found that 12 fatty acids were significantly changed in acute myeloid leukemia cell ferroptosis, including dihomo-γ-linolenic acid (DGLA), arachidonic acid (AA), docosahexaenoic acid (DHA), etc. Exogenous DGLA substantially increases the sensitivity to ferroptosis and induces ferroptosis alone in AML cells. …”
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Long-Chain Polyunsaturated Fatty Acids and Painful Temporomandibular Disorder in the Hispanic Community Health Study/Study of Latinos by Anne E. Sanders, Jianwen Cai, Martha L. Daviglus, Olga Garcia-Bedoya, Gary D. Slade

“…We hypothesized that diets high in omega-6 arachidonic acid (C20:4n-6, AA) and low in combined omega-3 eicosapentaenoic acid (C20:5n-3, EPA) and docosahexaenoic acid (C22:6n-3, DHA) would be associated with higher odds of painful temporomandibular disorder (TMD). …”
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Anti-Inflammatory, Antithrombotic, and Antioxidant Properties of Amphiphilic Lipid Bioactives from Shrimp by Alexandros Tsoupras, Paschalis Cholidis, Dimitrios Kranas, Evangelia Aikaterini Galouni, Anna Ofrydopoulou, Pavlos Efthymiopoulos, Katie Shiels, Sushanta Kumar Saha, George Z. Kyzas, Chryssa Anastasiadou

“…Significant amounts of UFAs, such as the monounsaturated fatty acid (MUFA) oleic acid (C18:1n9) and omega-3 (n3) polyunsaturated fatty acids (PUFAs) like eicosapentaenoic acid (EPA; C20:5n3) and docosahexaenoic acid (DHA; C22:6n3), were detected in the PLs of shrimp TAC extracts, with favorable anti-inflammatory values for their n6/n3 PUFA ratio. …”
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Comparison of the effects of 3 kinds of oils rich in omega-3 polyunsaturated fatty acids on glycolipid metabolism and lipoprotein subfractions by Hechun Liu, Feng Wang, Hui Xia, Da Pan, Ligang Yang, Shaokang Wang, Feng Zhao, Guiju Sun

“…Ninety T2DM patients with dyslipidemia were randomly assigned to take 3 g/day fish oil (FO, containing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)), 3 g/day perilla oil (PO, containing α-linolenic acid (ALA)), or 3 g/day blend oil (BO, containing EPA, DHA and ALA) for 3 months. 90 patients completed the intervention. …”
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Improving future fish consumption: A case study on developing fish products for preschool children by Hui Jia, Zdeněk Fuka, Jan Hora, Magdalena Marešová, Věra Adámková, Koushik Roy, Jan Mraz

“…The omega-3 fatty acid content (Eicosapentaenoic Acid (EPA) + Docosahexaenoic Acid (DHA) 265 mg/ 100 g in fish ham to 1067 mg/ 100 g in fish sausages) exceeded recommended daily intake of EPA+DHA (>100 %; average 233 %), underscoring health benefits, especially from other boneless parts of fish beyond just fillets. …”
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Liposome-like encapsulation of fish oil-based self-nano emulsifying formulation for improved bioavailability by Iqbal Ahmad, Aparana Dogra, Tanya Nagpal, Chandvi Sharma, Sudhakar Singh, Nikhil Shaiva, Gaurav Saini, Kanishk Luhach

“…Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are known for their significant health benefits, including cardiovascular protection, anti-inflammatory effects, and cognitive enhancement. …”
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Role of the Specialized Proresolving Mediator Resolvin D1 in Systemic Lupus Erythematosus: Preliminary Results by Luca Navarini, Tiziana Bisogno, Domenico Paolo Emanuele Margiotta, Alessandra Piccoli, Silvia Angeletti, Alice Laudisio, Massimo Ciccozzi, Antonella Afeltra, Mauro Maccarrone

“…Resolvin D1 (RvD1), a product of the metabolism of the omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA), acts as a specialized proresolving mediator which can contribute in restoring the homeostasis in inflamed tissues. …”
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International Society of Sports Nutrition Position Stand: Long-Chain Omega-3 Polyunsaturated Fatty Acids by Ralf Jäger, Jeffery L. Heileson, Sidney Abou Sawan, Broderick L. Dickerson, Megan Leonard, Richard B. Kreider, Chad M. Kerksick, Stephen M. Cornish, Darren G. Candow, Dean M. Cordingley, Scott C. Forbes, Grant M. Tinsley, Tindaro Bongiovanni, Roberto Cannataro, Bill I. Campbell, Shawn M. Arent, Jeffrey R. Stout, Douglas S. Kalman, Jose Antonio

“…The following conclusions represent the official position of the ISSN: Athletes may be at a higher risk for ω-3 PUFA insufficiency.Diets rich in ω-3 PUFA, including supplements, are effective strategies for increasing ω-3 PUFA levels.ω-3 PUFA supplementation, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), has been shown to enhance endurance capacity and cardiovascular function during aerobic-type exercise.ω-3 PUFA supplementation may not confer a muscle hypertrophic benefit in young adults.ω-3 PUFA supplementation in combination with resistance training may improve strength in a dose- and duration-dependent manner.ω-3 PUFA supplementation may decrease subjective measures of muscle soreness following intense exercise.ω-3 PUFA supplementation can positively affect various immune cell responses in athletic populations.Prophylactic ω-3 PUFA supplementation may offer neuroprotective benefits in athletes exposed to repeated head impacts.ω-3 PUFA supplementation is associated with improved sleep quality.ω-3 PUFA are classified as prebiotics; however, studies on the gut microbiome and gut health in athletes are currently lacking.…”
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Modulatory effect of Echium plantagineum oil on the n-3 LC-PUFA biosynthetic capacity of chicken (Gallus gallus) by Jesús Villora, José Antonio Pérez, Nieves Guadalupe Acosta, Deiene Rodríguez-Barreto, Pedro Juan Alonso, Mónica B. Betancor, Alexandr Torres, Sergio Álvarez, Covadonga Rodríguez

“…Poultry can be a sustainable source of eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3) through the bioconversion of dietary alpha-linolenic acid (ALA, 18:3n-3). …”
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Effectiveness of hCMV, mEF1a and mAct promoters on driving of foreign gene expression in transgenic zebrafish by . Alimuddin, G. Yoshizaki, O. Carman, T. Takeuchi

“… Highly unsaturated fatty acids (HUFA), especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have long been recognized for its beneficial effect for human health and development.   …”
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Nutritional Quality of Edible Marine Bivalves from the Southern Coast of Italy, Mediterranean Sea by Francesca Biandolino, Antonella Di Leo, Isabella Parlapiano, Loredana Papa, Santina Giandomenico, Lucia Spada, Ermelinda Prato

“…Among PUFAs, eicosapentaenoic (EPA) and docosahexaenoic acids (DHA) exhibited highest levels in M. galloprovincialis (11.74%) and in M. varia (14.41%), respectively. …”
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