A Dietary Treatment Improves Cerebral Blood Flow and Brain Connectivity in Aging apoE4 Mice by Maximilian Wiesmann, Valerio Zerbi, Diane Jansen, Roy Haast, Dieter Lütjohann, Laus M. Broersen, Arend Heerschap, Amanda J. Kiliaan

“…A dietary approach (Fortasyn) including docosahexaenoic acid, eicosapentaenoic acid, uridine, choline, phospholipids, folic acid, vitamins B12, B6, C, and E, and selenium has been proposed for dietary management of AD. …”
Get full text

Characterization of phospholipid profiles of egg yolks: Newly classified plasmalogens, distribution of polyunsaturated fatty acids, and the effects of dietary enrichment by Le Cheng, Xinlei Yuan, Ming Zhang, Jianguo Dong, Yao Wu, Rang Wang, Yixuan Li, Lishui Chen, Bing Fang

“…The study firstly found that egg yolks were also rich in glucosylceramides, galactosylceramides, lactosylceramides, gangliosides, and plasmalogens with polyunsaturated fatty acids (PUFAs) at the high bioavailable sn-2 position. Docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), α-Linolenic acid (ALA), and arachidonic acid (ARA) were esterified at sn-1 position of PC and sn-2 position of PE, phosphatidyl inositol (PI) and phosphatidic acid (PA). …”
Get full text

Associations of Plasma Phospholipid Omega-6 and Omega-3 Polyunsaturated Fatty Acid Levels and MRI Measures of Cardiovascular Structure and Function: The Multiethnic Study of Athero... by Jennifer S. Anderson, Jennifer A. Nettleton, W. Gregory Hundley, Michael Y. Tsai, Lyn M. Steffen, Rozenn N. Lemaitre, David Siscovick, João Lima, Martin R. Prince, David Herrington

“…Associations of plasma phospholipid fatty acid levels (arachidonic acid, linoleic acid, eicosapentaenoic acid, docosahexaenoic acid (DHA), and alpha-linolenic acid) with cardiac magnetic resonance imaging measures of left ventricular (LV) mass, LV volume, ejection fraction, stroke volume, and aortic distensibility were investigated in 1,274 adults. …”
Get full text

GC-MS analysis, antimicrobial and antiulcer evaluations of ginger-infused virgin coconut oil by Ibeabuchi Jude Ali, Okorie Ndidiamaka H, Adonu Cyril C, Omeh Romanus C, Obidiegwu Onyeka C, Okonkwo Raymond M, Okafor Judith O, Okoye Festus BC

“…The GC-MS analysis identified the presence of lauric acid methyl ester, Myristic acid, Palmitic Acid, Oleic acid, Capric acid, Stearic acid, Caryophyllene, Docosahexaenoic Acid methyl ester. At 100 mg/ml, inhibition zone diameter (IZD) ranged from 10-16 mm for various strains of bacteria and 10-21 mm for various strains of fungi. …”
Get full text

Dietary DHA Regulated the Androgen Production in Male Chinese Tongue Sole Cynoglossus semilaevis by Jiahao Liu, Qiang Ma, Feiran Zhang, Qingyan Gao, Zhijun Zhang, Yuliang Wei, Mengqing Liang, Houguo Xu

“…Long-chain polyunsaturated fatty acids (LC-PUFA) play key roles in sex steroid hormone synthesis in fish. Regarding docosahexaenoic acid (DHA), currently the regulating effects were mostly evaluated in female fish rather than males. …”
Get full text

Phosphomolybdic acid boosts polyunsaturated fatty acid and neutral lipid production in Phaeodactylum tricornutum by Kun-Tao Peng, Bing-Hong Xiong, Gao Cheng, Gao Cheng, Yuan-Hong Zhong, Yuan-Hong Zhong, Lin Yu, Lin Yu

“…Furthermore, microalgae are emerging as promising sources of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). …”
Get full text

Multicomponent Dietary Supplementation: Impact on Tear Secretion and Ocular Surface Inflammation in Dry Eye Syndrome Patients by Shih-Chien Huang, Yen-Ping Lei, Min-Chien Hsiao, Yu-Kai Hsieh, Quei-Ping Tang, Connie Chen, Min-Yen Hsu

“…In total, 52 participants were randomly assigned to control (<i>n</i> = 23) and supplement (45 mg/day eicosapentaenoic acid, 30 mg/day docosahexaenoic acid, 30 mg/day lutein, and 1.8 mg/day zeaxanthin; <i>n</i> = 29) groups for 12 weeks. …”
Get full text

Variation in the Lipid Profile of Pacific Oyster ( Crassostrea gigas ) Cultured in Khanh Hoa Coast, Vietnam, Based on Location and Harvest Period by Minh Van Nguyen, Derrick Kakooza, Anh Phuong Thi Tran, Vy Thao Thi Tran

“…The dominant polyunsaturated fatty acids of oysters from the three farming areas were eicosapentaenoic acid (9.09–13.77 g/100 g TL) and docosahexaenoic acid (6.71–16.47 g/100 g TL). Based on the present findings, it can be concluded that the Pacific oyster C. gigas cultured in Khanh Hoa, Vietnam is a promising source of highly nutritious exploitable lipids.…”
Get full text

Plasma Fatty Acids in Zambian Adults with HIV/AIDS: Relation to Dietary Intake and Cardiovascular Risk Factors by Christopher K. Nyirenda, Edmond K. Kabagambe, John R. Koethe, James N. Kiage, Benjamin H. Chi, Patrick Musonda, Meridith Blevins, Claire N. Bosire, Michael Y. Tsai, Douglas C. Heimburger

“…PUFA intakes showed modest correlations with corresponding plasma levels; Spearman correlations were 0.36 (p<0.01) for eicosapentaenoic acid and 0.21 (p=0.005) for docosahexaenoic acid. While there were no significant associations (p>0.05) between total plasma PUFA and C-reactive protein (CRP) or lipid levels, plasma arachidonic acid was inversely associated with CRP and triglycerides and positively associated with HDL-C, CD4+ T-cell count, and plasma albumin (p<0.05). …”
Get full text

The association of dietary approaches to stop hypertension measured by the food frequency questionnaire with metabolic syndrome and some inflammatory biomarkers in adolescents with... by Maryam Behrooz, Alireza Ostadrahimi, Samaneh Hajjarzadeh, Mirhadi Mousavi, Afshin Ghalegolab Behbahani, Siamak Shiva

“…In addition, the DASH score was positively associated with potassium, magnesium, sodium, vitamins D and C, docosahexaenoic acid, and soluble fiber (P < 0.05). Conclusion In the current study, there was no significant association between adherence to the DASH diet and odds of metabolic syndrome, and other cardiometabolic risk factors in adolescent. …”
Get full text

Akkermansia muciniphila-directed polyphenol chlorogenic acid intervention for obesity in mice by Xiaoxiang Gao, Chenbo Yue, Ruocen Tian, Leilei Yu, Fengwei Tian, Jianxin Zhao, Wei Chen, Qixiao Zhai

“…Microbiome and metabolomics revealed that the increased abundance of A. muciniphila resulted from the inhibition of CGA on Desulfovibrio and Alistipes and the influence of docosahexaenoic acid, β-hydroxybutyrate, and N-acetyl-lactosamine. …”
Get full text

Association of ultra-processed food-related metabolites with selected biochemical markers in the UK Biobank by Anthony Kityo, Byeonggeun Choi, Jung-Eun Lee, Chulho Kim, Sang-Ah Lee

“…Acetoacetate, acetone, high-density lipoprotein (HDL) diameter, docosahexaenoic acid, linoleic acid, ω-3 fatty acids (FA), total lipids in large HDL cholesterol, and valine levels were decreased, but free cholesterol in extremely small very low-density lipoproteins (LDL), glutamine, glycine, glycoprotein acetyls, lactate, saturated FA, sphingomyelins, triglycerides in large LDL, and triglycerides in medium HDL levels were increased with high UPF intake. …”
Get full text

Per1/Per2 double knockout transcriptome analysis reveals circadian regulation of hepatic lipid metabolism by Yiran Bu, Si Chen, Mengcheng Ruan, Libang Wu, Hualin Wang, Na Li, Xiuju Zhao, Xiaoli Yu, Zhiguo Liu

“…This study aimed to explore the effects of Per1/Per2 double knockout (DKO) on hepatic lipid metabolism in mice under HFD and HFD with docosahexaenoic acid (DHA) substitution. Methods and results: Both wild type (WT) and DKO male C57BL/6 mice were fed with normal chow diet (CON), HFD, or HFD with DHA substitution (AO) for 15 weeks. …”
Get full text

Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites by Yun Teng, Chao Luo, Xiaolan Qiu, Jingyao Mu, Mukesh K. Sriwastva, Qingbo Xu, Minmin Liu, Xin Hu, Fangyi Xu, Lifeng Zhang, Juw Won Park, Jae Yeon Hwang, Maiying Kong, Zhanxu Liu, Xiang Zhang, Raobo Xu, Jun Yan, Michael L. Merchant, Craig J. McClain, Huang-Ge Zhang

“…We further demonstrate that GELN aly-miR159a-3p enhances anti-PD-L1 therapy in melanoma by inhibiting the expression of recipient bacterial phospholipase C (PLC) and increases the accumulation of docosahexaenoic acid (DHA). An increased level of circulating DHA inhibits PD-L1 expression in tumor cells by binding the PD-L1 promoter and subsequently prevents c-myc-initiated transcription of PD-L1. …”
Get full text

International expert consensus on micronutrient supplement use during the early life course by Irene Cetin, Roland Devlieger, Erika Isolauri, Rima Obeid, Francesca Parisi, Stefan Pilz, Lenie van Rossem, Maternal Nutrition Delphi Study Group, Régine Steegers-Theunissen

“…For the periods of preconception, pregnancy and lactation, questions focused on the importance and strength of evidence for supplement use with the following micronutrients for low- and high-risk populations: folic acid, choline, iodine, magnesium, calcium, iron, selenium, docosahexaenoic acid (DHA), and vitamins B1, B2, B6, B12, D and K. …”
Get full text

Food groups, macronutrient intake and objective measures of total carotenoids and fatty acids in 16-to-24-year-olds following different plant-based diets compared to an omnivorous... by Synne Groufh-Jacobsen, Christel Larsson, Isabelle Mulkerrins, Dagfinn Aune, Anine Christine Medin

“…The lowest blood levels of eicosapentaenoic acid and docosahexaenoic acid were found in vegans and lacto-ovo-vegetarians.…”
Get full text

Effect of Kind and Dosage of Enrichment Materials on the Nutritional Quality of Rotifers Especially n3-HUFA by Muhammad Agus Suprayudi

“…Adapun rotifera yang diperkaya dengan EPA-TAG memiliki profil asam lemak yang lebih lengkap terutama ditinjau dari kandunga EPA dan docosahexaenoic acid (DHA) nya.  Selanjutnya rotifera yang diperkaya dengan Nannochloropsis oculata memiliki populasi yang tertinggi dibanding perlakuan lainnya. …”
Get full text

Efferocytosis and inflammation: a bibliometric and systematic analysis by Xin Cao, Xin Cao, Fen Li, Fen Li, Xi Xie, Xi Xie, Guanghui Ling, Guanghui Ling, Xiaoyu Tang, Xiaoyu Tang, Wenfang He, Jing Tian, Jing Tian, Yan Ge, Yan Ge

“…Keyword analysis identified “activation,” “tam receptors,” “docosahexaenoic acid” “systemic lupus erythematosus,” “myocardial infarction” and “alveolar macrophages” as core topics, indicating a concentrated trend in the mechanism of physiological state and inflammatory diseases such as autoimmune, cardiovascular, and pulmonary diseases. …”
Get full text

Optimization of the Process for Defatting Sea Cucumber Powder by Supercritical CO2 Extraction and Its Effect on Volatile Flavor Compounds by Gongming WANG, Hui HUANG, Yuzhu DING, Jinglin XUE, Zhiqiang SHU, Yuexin JING, Chunna JIAO, Jian ZHANG

“…In contrast, the proportions of polyunsaturated fatty acids such as arachidonic acid (ARA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) were higher in the extracted sea cucumber powder. …”
Get full text

Fatty Acid Composition and Anticancer Activity of Neutral and Polar Lipids of Pacific Oyster ( Crassostrea gigas ) Cultured in Khanh Hoa Coast in Vietnam by Minh Van Nguyen, Derrick Kakooza, Thi Hong Tuoi Do, Anh Phuong Thi Tran, Han The Nguyen, Ngoc Quang Tran

“…Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were identified as the most prevalent polyunsaturated fatty acids, while oleic acid and palmitic acid were the predominant monounsaturated and saturated fatty acids, respectively. …”
Get full text