Scoping review of costs of implementation strategies in community, public health and healthcare settings by Hongmei Wang, Jungyoon Kim, Tzeyu L Michaud, Emiliane Pereira, Gwenndolyn Porter, Caitlin Golden, Jennie Hill, Cindy Schmidt, Paul A Estabrooks

“…The wide range of costs was due to the varying scales of the studies, intended audiences/diseases and the complexities of the strategy components. …”
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Nobiletin Attenuates Pathological Cardiac Remodeling after Myocardial Infarction via Activating PPARγ and PGC1α by Yufei Zhou, Ting Yin, Mengsha Shi, Mengli Chen, Xiaodong Wu, Kai Wang, Iokfai Cheang, Yanxiu Li, Hongcai Shang, Haifeng Zhang, Xinli Li

“…Nobiletin (NOB), an active monomer extracted from the peel of citrus fruit, has been reported to have beneficial effects in cardiovascular diseases. Our study was aimed at describing the specific mechanisms through which NOB protects against pathological cardiac remodeling after MI. …”
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IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury by Hongshuang Su, Xiaoxi Lin, Ayinuer Paredong, Ayinuer Paredong, Congcong Yao, Yan Zhang, Mengke Geng, Yuqian Guan, Lichao Gong, Feng Jiang, Qi Lv, Songtao Shou, Heng Jin

“…IL-6, a multifunctional cytokine, plays a crucial role in the occurrence and development of various kidney diseases. It can promote inflammatory responses, cell proliferation, fibrosis, and other processes. …”
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Clinical study on the treatment of chronic heart failure with a novel D‐shant atrium shunt device by Xiaoke Shang, Mei Liu, Yucheng Zhong, Xueli Wang, Song Chen, Xiaojuan Fu, Ming Sun, Mingxing Xie, Yuhe Ke, Ying Guan, Changdong Zhang, Nianguo Dong

“…Abstract Background Atrial septal shunt devices might improve hospitalizations and also prognosis in heart failure with increased pulmonary pressures due to left heart diseases. In recent years, atrial shunt devices have been used for the treatment of chronic heart failure, but there remains a lack of clinical experience. …”
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MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells by Rowan Abdelbary, Rowan Abdelbary, Manon Ragheb, Manon Ragheb, Shereen A. El Sobky, Nagwa El-Badri, Nourhan Aboud, Ahmed Tawheed, Asmaa Gomaa, Mona Zidan, Ramy K. Aziz, Abd Elrahman Abouzid, Radwa Ayman Salah, Mohamed El-Kassas, Imam Waked, Ahmed Moustafa, Ahmed Moustafa, Injie Omar Fawzy, Nada El-Ekiaby, Ahmed Ihab Abdelaziz

“…IntroductionThe role of miRNAs in regulating variable molecular functions has been sought by scientists for its promising utility in regulating the immune response and, hence, in treating various diseases. In hepatocellular carcinoma (HCC) specifically, a reduction in the number and efficiency of circulating and intrahepatic natural killer (NK) cells has been reported. …”
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Clinical Features of COVID‐19 Associated Pulmonary Aspergillosis: A Multicenter, Retrospective Study by Yasheng Zhan, Guojun He, Cheng Zhong, Yake Yao, Jiangying Zhou, Tong Li, Hua Zhou

“…Conclusion The incidence of CAPA in patients with COVID‐19 admitted to the ICU was 19.44%, all patients with CAPA had a history of chronic underlying diseases, and all had a history of high dose glucocorticoid. …”
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Association of over-the-counter mouthwash use with markers of nitric oxide metabolism, inflammation, and endothelial function—a cross-sectional study by Kai Guo, Kaumudi Joshipura, Karina Ricart, Rakesh P. Patel, Barbara A. Gower, Oelisoa Mireille Andriankaja, Evangelia Morou-Bermudez

“…This raises concerns about its potential effects on the levels of inflammatory and endothelial biomarkers associated with cardiometabolic diseases.…”
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Clonal hematopoiesis of indeterminate potential is a risk factor of gastric cancer: A Prospective Cohort in UK Biobank study by Zhihui Xi, Huolun Feng, Kunling Chen, Xin Guo, Dandan Zhu, Jiabin Zheng, Yong Li

“…Previous and diagnosed cancer or diseases were collected from self-reported and in-hospital records. …”
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The First Large Identification of 3ANX and NX Producing Isolates of <i>Fusarium graminearum</i> in Manitoba, Western Canada by Maria Antonia Henriquez, Srinivas Sura, Sean Walkowiak, David Kaminski, Anne Kirk, Mark W. Sumarah, Parthasarathy Santhanam, Nina Kepeshchuk, Jules Carlson, E. RoTimi Ojo, Pam de Rocquigny, Holly Derksen

“…Fusarium head blight, caused by <i>Fusarium graminearum</i>, continues to be one of the most important and devastating fungal diseases on cereal grains including wheat, barley, and oat crops. …”
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Exploring the role of ESR1 mutations in metastatic hormone receptor-positive breast cancer T cell immune surveillance disruption by Morgane Lopez, Laurie Spehner, Fabrice André, Julien Viot, Evan Seffar, Amélie Marguier, Elsa Curtit, Guillaume Meynard, Erion Dobi, Sylvain Ladoire, Romain Boidot, Romain Loyon, Valentin Derangere, François-Clément Bidard, Christophe Borg, Laura Mansi, Marie Kroemer

“…In a data set generated from BC patients refractory to conventional therapy we showed that ESR1 mutations are correlated in advanced diseases with downregulation of molecules involved in antigen presentation and with loss HLA Class I gene expression. …”
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Beta 3 adrenoreceptors protect from hypertrophic remodelling through AMP‐activated protein kinase and autophagy by Emilie Dubois‐Deruy, Roselle Gelinas, Christophe Beauloye, Hrag Esfahani, Lauriane Y.M. Michel, Chantal Dessy, Luc Bertrand, Jean‐Luc Balligand

“…Abstract Aims The abundance of beta 3‐adrenergic receptors (β3‐ARs) is upregulated in diseased human myocardium. We previously showed that cardiac‐specific expression of β3‐AR inhibits the hypertrophic response to neurohormonal stimulation. …”
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Metabolomics, network pharmacology, and microbiome analyses uncover the mechanisms of the Chinese herbal formula for the improvement of meat quality in spent hens by Zhihua Li, Md. Abul Kalam Azad, Chengwen Meng, Xiangfeng Kong, Jue Gui, Wenchao Lin, Yadong Cui, Wei Lan, Qinghua He

“…Chinese herbs have been widely used as medicine for a long time to prevent diseases and as nutrient supplements to improve the product quality. …”
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The Characteristics and Mortality of Osteoporosis, Osteomyelitis, or Rheumatoid Arthritis in the Diabetes Population: A Retrospective Study by Jin-Feng Huang, Qi-Nan Wu, Xuan-Qi Zheng, Xiao-Lei Sun, Chen-Yu Wu, Xiao-Bing Wang, Chen-Wei Wu, Bin Wang, Xiang-Yang Wang, Michael Bergman, Ai-Min Wu

“…We suggest that increased attention should therefore be given to these diseases in the population with diabetes, especially in efforts to develop preventative and treatment strategies.…”
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Predictive factors of fibrotic interstitial lung abnormality on high-resolution computed tomography scans: a prospective observational study by Kazuya Ichikado, Hidenori Ichiyasu, Kazuhiro Iyonaga, Kodai Kawamura, Yuko Yasuda, Keisuke Anan, Hiroko Okabayashi, Kimitaka Akaike, Noritaka Higashi, Takeshi Johkoh, Kiminori Fujimoto, Tetsuo Saito, Jun Morinaga, Minoru Yoshida, Katsuhiko Mitsuzaki, Takuro Sakagami

“…These findings may assist non-radiological physicians in referring patients to specialists for early intervention in progressive fibrotic interstitial lung diseases. Trial registration number/date UMIN000045149/2021.12.1.…”
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600 meters to VO2max: Predicting Cardiorespiratory Fitness with an Uphill Run by Kübra Stoican, Regina Oeschger

“…There is an inverse relationship between CRF and heart diseases or mortality due to any potential cause in healthy individuals [1]. …”
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Current applications and challenges in large language models for patient care: a systematic review by Felix Busch, Lena Hoffmann, Christopher Rueger, Elon HC van Dijk, Rawen Kader, Esteban Ortiz-Prado, Marcus R. Makowski, Luca Saba, Martin Hadamitzky, Jakob Nikolas Kather, Daniel Truhn, Renato Cuocolo, Lisa C. Adams, Keno K. Bressem

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Efficacy and safety of the pulsed electromagnetic field in osteoarthritis: a meta-analysis by Ziying Wu, Xiang Ding, Guanghua Lei, Chao Zeng, Jie Wei, Jiatian Li, Hui Li, Tuo Yang, Yang Cui, Yilin Xiong, Yilun Wang, Dongxing Xie

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Epidemiological Dynamics of Extended-Spectrum β-Lactamase- or AmpC β-Lactamase-Producing Escherichia coli Screened in Apparently Healthy Chickens in Uganda by Steven Kakooza, Damien Munyiirwa, Paul Ssajjakambwe, Edrine Kayaga, Dickson Stuart Tayebwa, Dickson Ndoboli, Loreen Basemera, Esther Nabatta, Maria Agnes Tumwebaze, John Baligwamunsi Kaneene

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Roles of the rpoEc-chrR-chrA operon in superoxide tolerance and β-lactam susceptibility of Stenotrophomonas maltophilia by Ren-Hsuan Ku, Hsu-Feng Lu, Li-Hua Li, Li-Hua Li, Ting-Yu Yeh, Yi-Tsung Lin, Yi-Tsung Lin, Tsuey-Ching Yang

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Identification of Potential Diagnostic Biomarkers of Carotid Atherosclerosis in Obese Populations by Wu X, Pan J, Pan X, Kang J, Ren J, Huang Y, Gong L, Li Y

“…Xize Wu,1,&ast; Jiaxiang Pan,2,&ast; Xue Pan,1,3,&ast; Jian Kang,1 Jiaqi Ren,1 Yuxi Huang,1 Lihong Gong,2,4 Yue Li2,4 1Graduate School, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, 110847, People’s Republic of China; 2Department of Cardiology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, 110032, People’s Republic of China; 3College of Traditional Chinese Medicine, Dazhou Vocational College of Chinese Medicine, Dazhou, Sichuan, 635000, People’s Republic of China; 4Liaoning Provincial Key Laboratory of TCM Geriatric Cardio-Cerebrovascular Diseases, Shenyang, Liaoning, 110032, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Lihong Gong; Yue Li, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 33, Beiling Street, Huanggu District, Shenyang, Liaoning, 110032, People’s Republic of China, Tel +86 024-82961105, Email Linda1795@sina.com; med_liyue@163.comObjective: This study aimed to investigate the potential mechanisms and biomarkers between Obesity (OB) and carotid atherosclerosis (CAS).Methods: The GSE12828, GSE125771, GSE43292, and GSE100927 datasets were combined and normalized to obtain CAS-related differentially expressed genes (DEGs), and OB-related DEGs were obtained from the GSE151839 dataset and the GeneCards database. …”
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