Targeting lipid metabolism of macrophages: A new strategy for tumor therapy by Nan Shao, Hui Qiu, Jing Liu, Daimin Xiao, Juanjuan Zhao, Chao Chen, Jiajia Wan, Mengmeng Guo, Guiyou Liang, Xu Zhao, Lin Xu

“…Background: Lipid metabolism has been implicated in a variety of normal cellular processes and strongly related to the development of multiple diseases, including tumor. Tumor-associated macrophage (TAM) has emerged as a crucial regulator in tumorigenesis and promising target for tumor treatment.Aim of review: A thorough understanding of TAM lipid metabolism and its value in tumorigenesis may provide new ideas for TAM-based anti-tumor therapy.Key scientific concepts of review: TAMs can be divided into two main types, M1-like TAMs and M2-like TAMs, which play anti-tumor and pro-tumor functions in tumor occurrence and development, respectively. …”
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Follow up through Endoscopical – Histological Studies and Helicobacter Pylori Infections in Patients Suffering from Gastric Ulcers by Marcos Félix Osorio Pagola, Antonio Moré Pérez, Libán Álvarez Cáceres, Juan Luis de Pasos Carrazana, Anagalys Ortega Alvelay

“…The commonest chronic infection worldwide is caused by Helicobacter pylori and it is associated to gastro duodenal diseases. <strong><br />Objective: </strong>To determine the endoscopic-biopsic follow up and to set the frequency of infection due to Helicobacter pylori in those patients who suffer from gastric ulcers. …”
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Phylogenetic analysis of dermatophytes isolated from small domestic animals by A. M. Smagulova, E. V. Kukhar, T. I. Glotova, A. G. Glotov

“…Dermatophytoses are diseases of skin and its accessory structures that are widely spread worldwide. …”
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Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms by Yue Xiao, Yingxuan Feng, Jianxin Zhao, Wei Chen, Wenwei Lu

“…Background: Population aging has become a primary global public health issue, and the prevention of age-associated diseases and prolonging healthy life expectancies are of particular importance. …”
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Anti-Inflammatory Activity of Diterpenoids from Celastrus orbiculatus in Lipopolysaccharide-Stimulated RAW264.7 Cells by Hyun-Jae Jang, Kang-Hoon Kim, Eun-Jae Park, Jeong A. Kang, Bong-Sik Yun, Seung-Jae Lee, Chan Sun Park, Soyoung Lee, Seung Woong Lee, Mun-Chual Rho

“…Therefore, these results demonstrated that diterpenoids 1 and 3 obtained from C. orbiculatus may be considered a potential candidate for the treatment of inflammatory diseases.…”
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Candidate Genes Associated with Delayed Neuropsychomotor Development and Seizures in a Patient with Ring Chromosome 20 by Thiago Corrêa, Amanda Cristina Venâncio, Marcial Francis Galera, Mariluce Riegel

“…Defects in these bioprocesses are associated with the development of neurological diseases, intellectual disability, neuropathies, and seizures. …”
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Comparative assessment of <i>Bifidobacterium bifidum, Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus rhamnosus</i> and <i>Saccharomyces boulardii</i> efficacy at d... by V. T. Ivashkin, O. M. Drapkina, A. A. Sheptulin, O. S. Shifrin, Ye. A. Poluektova, S. Yu. Kuchumova

“…In 47 patients with diagnosis of IBS-D, confirmed by conformity of symptoms to Rome-III criteria and absence of organic diseases according to carried out investigation comparative analysis of effect of probiotics and placebo on development of main clinical symptoms, state of intestinal microflora and quality of life was applied. …”
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Efficacy and safety of sublingual immunotherapy using a combination of Dermatophagoides pteronyssinus and Blomia tropicalis extracts in patients with allergic rhinitis: A randomize... by Priscilla Rios Cordeiro Macedo, MD, MSc, Priscila Moraes, MD, Luísa Karla Arruda, MD, PhD, Fábio Fernandes Morato Castro, MD, PhD, Jorge Kalil, MD, PhD, Clóvis Eduardo Santos Galvão, MD, PhD

“…Background: Allergen immunotherapy is the only treatment that may modify the natural course of allergic diseases. Sublingual immunotherapy (SLIT) is a promising treatment, especially for children. …”
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Arterial Stiffness Is Associated with Peripheral Sensory Neuropathy in Diabetes Patients in Ghana by Kwame Yeboah, Jennifer A. Agyekum, Richard N. A. Owusu Mensah, Patrick K. Affrim, Linda Adu-Gyamfi, Rita O. Doughan, Afua B. Adjei

“…Arterial stiffness is a predictor of cardiovascular diseases and microvascular complications associated with diabetes. …”
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Characterization and Antifungal Activity of Limonoid Constituents Isolated from Meliaceae Plants Melia dubia, Aphanamixis polystachya, and Swietenia macrophylla against Plant Patho... by Thanh Nguyen Tan, Hieu Tran Trung, Quang Le Dang, Hien Vu Thi, Hoang Dinh Vu, Tuan Nguyen Ngoc, Hoai Thu Thi Do, Thanh Huong Nguyen, Dang Ngoc Quang, Thang Tran Dinh

“…Our study results demonstrated the discovery of antifungal and lead compounds from the group of limonoids for application in the control of fungal plant diseases.…”
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Effects of genetic ablation and pharmacological inhibition of HuR on gene expression, iron metabolism, and hormone levels by Nathalie Idlin, Sivakumar Krishnamoorthy, Magdalena Wolczyk, Mouad Fakhri, Michal Lechowski, Natalia Stec, Jacek Milek, Pratik Kumar Mandal, Jaroslaw Cendrowski, Christos Spanos, Magdalena Dziembowska, Katarzyna Mleczko-Sanecka, Juri Rappsilber, Gracjan Michlewski

“…Elevated HuR levels are associated with multiple disorders, including cancer and neurodegenerative diseases. Despite the identification of small molecule inhibitors targeting HuR, their detailed characterization remains limited. …”
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Exendin-4 Protects against Hyperglycemia-Induced Cardiomyocyte Pyroptosis via the AMPK-TXNIP Pathway by Hong Wei, Rui Bu, Qinghui Yang, Jing Jia, Tao Li, Qiuping Wang, Yanjun Chen

“…Exendin-4, a GLP analog, promotes survival of cardiomyocytes in cardiovascular diseases, including diabetic cardiomyopathy. However, the role of Exendin-4 in cardiac pyroptosis remains to be elucidated. …”
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The Effect of Airflow-Assisted Parameters on Droplet Deposition on Soybean Leaves at the V7 Growth Stage by Yuefu Guo, Hao Wang, Wenfeng Sun, Yongli Sun, Rui Xing, Kaige Zhang, Xiaocheng Fang, Bin Sui, Jiehao Xu

“…In agricultural production, the underside of crop leaves and the middle-lower canopy are key areas where pests and diseases typically develop at early stages. Increasing droplet deposition in these critical regions is essential for improving pesticide efficacy and crop yield. …”
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Single Exposure to Low-Intensity Focused Ultrasound Causes Biphasic Opening of the Blood-Brain Barrier Through Secondary Mechanisms by Tasneem A. Arsiwala, Kathryn E. Blethen, Cullen P. Wolford, Geoffrey L. Pecar, Dhruvi M. Panchal, Brooke N. Kielkowski, Peng Wang, Manish Ranjan, Jeffrey S. Carpenter, Victor Finomore, Ali Rezai, Paul R. Lockman

“…<b>Background/Objective:</b> The blood–brain barrier (BBB) is selectively permeable, but it also poses significant challenges for treating CNS diseases. Low-intensity focused ultrasound (LiFUS), paired with microbubbles is a promising, non-invasive technique for transiently opening the BBB, allowing enhanced drug delivery to the central nervous system (CNS). …”
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Prevalence and characteristics of HPV vaccine hesitancy among parents of adolescent females across Saudi Arabia by Sahar Othman, Ranya Ghamri, Wala Alhamadah, Anwaar Alsatty, Dhuha Khesfaty, Ohoud Alghamdi, Ragad Arbaein, Alaa M. Baglagel, Jumana Khayyat, Bushra Almalki

“…PurposeVaccination against human papillomavirus (HPV) is pivotal in preventing HPV-related diseases, including cervical cancer. However, vaccine hesitancy and their related factors among parents of adolescent females present a significant obstacle to achieving high vaccination rates. …”
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Use of a synthetic form Avrodes for transfer of leaf rust resistance from Aegilops speltoides to common wheat by R. O. Davoyan, I. V. Bebyakina, E. R. Davoyan, D. S. Mikov, E. D. Badaeva, I. G. Adonina, E. A. Salina, A. N. Zinchenco, Y. S. Zubanova

“…Diploid wild relative of wheat – Aegilops speltoides – is a valuable source of genes for resistance to diseases. The synthetic form Avrodes (BBAASS) was used as a bridge to transfer leaf rust resistance genes from Ae. speltoides to common wheat. …”
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STUDY OF THE EFFECT OF HYPOTHERMIC CONSERVATION ON THE INTRACELLULAR SODIUM CONCENTRATION IN THE ENDOTHELIUM OF CORNEAL TRANSPLANTS by G. S. Baturina, I. G. Palchikova, A. A. Konev, E. S. Smirnov, L. E. Katkova, E. I. Solenov, I. А. Iskakov

“…Advancements in the surgical treatment of corneal endothelial diseases depend on progress in graft conservation and its related advantages in assessing the suitability of grafts for transplantation. …”
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Characterization of Stroke Patients in an Intensive Care Unit by Marianela Planes Fajardo, Georgia Díaz-Perera Fernández, Maylín Isabel Alonso Martínez, Aurora Calzada Fajardo

“…<strong>Background:</strong> cerebrovascular diseases represent a potentially serious panorama, with avoidable consequences and whose prognosis depends on the speed and effectiveness of the actions. …”
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Whole-genome association studies of distribution of developmental abnormalities and other breeding-valuable qualitative traits in offspring of the Russian large-white boars by A. A. Traspov, O. V. Kostyunina, A. A. Belous, T. V. Karpushkina, N. A. Svejenceva, N. A. Zinovieva

“…Identifying genome regions that are directly or indirectly associated with developmental defects and malformations in domesticated pigs can help identify genomic traits used as biomarkers of the structural and functional composition of the body, their metabolic status and genetic diseases as well. Such studies are directly related to the improvement of the economic efficiency, as they allow identification and exclusion of defect animals, who may carry target genes not appearing phenotypically, from the breeding process. …”
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Antioxidant, Anti-α-Glucosidase, Anti-Tyrosinase, and Anti-Acetylcholinesterase Components from Stem of <i>Rhamnus formosana</i> with Molecular Docking Study by Chia-Hsuan Tsai, Ya-Lun Liou, Sin-Min Li, Hsiang-Ruei Liao, Jih-Jung Chen

“…These findings suggest that bioactive extracts and compounds from the stems of <i>R. formosana</i> may have potential as natural antioxidant, anti-α-glucosidase, anti-AChE, and anti-tyrosinase drug candidates or dietary supplements for the management of oxidative stress-related conditions, including hyperglycemia, pigmentation disorders, and neurodegenerative diseases.…”
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