Cyanidin-3-O-Glucoside Modulates the In Vitro Inflammatory Crosstalk between Intestinal Epithelial and Endothelial Cells by Daniela Ferrari, Francesco Cimino, Deborah Fratantonio, Maria Sofia Molonia, Romina Bashllari, Rossana Busà, Antonella Saija, Antonio Speciale

“…Thus, anthocyanins could contribute to the management of chronic gut inflammatory diseases.…”
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mTOR downregulation promotes anti-inflammatory responses via the CCL3-CCR5 axis in hypoxic retinopathy by Tae Kwon Moon, Im Kyeung Kang, Kyoung Jin Lee, Ji Hyun Kim, Hee Jong Kim, A. Reum Han, Ha-Na Woo, Joo Yong Lee, Jun-Sub Choi, Keerang Park, Heuiran Lee

“…These findings thus highlight the potential of AAV2-shmTOR to exert anti-inflammatory effects by influencing the mTOR and subsequent CCL3-CCR5 pathways in hypoxic retinopathies, presenting a novel therapeutic approach for retinal diseases marked by hypoxia-driven inflammation.…”
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The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy by M. L. Perepechaeva, A. Yu. Grishanova, E. A. Rudnitskaya, N. G. Kolosova

“…The mitochondria-targeted antioxidant SkQ1 is a novel drug thought to retard development of age-related diseases. It has been shown that SkQ1 reduces clinical signs of retinopathy in senescence-accelerated OXYS rats, which are a known animal model of human age-related macular degeneration (AMD). …”
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Traditional Medicinal Vegetables in Northern Uganda: An Ethnobotanical Survey by Rebecca Nakaziba, Maxson Kenneth Anyolitho, Sharon Bright Amanya, Crispin Duncan Sesaazi, Frederick Byarugaba, Jasper Ogwal-Okeng, Paul E. Alele

“…Northern Uganda has numerous traditional vegetables with medicinal benefits. Diseases treated range from gastrointestinal to reproductive through musculoskeletal abnormalities. …”
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ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTS by A. V. Konstantinov, S. K. Starov, V. I. Diev, N. V. Moroz, E. V. Kurnenkova, D. K. Basova, A. V. Kononov, K. Yu. Fedoseyev, V. P. Melnikov

“…The vaccination induced high level of virus neutralizing antibodies against each of the above listed diseases and ensured formation of strong immunity tat is supported by the results of tallenge of sheep with virulent sheep pox virus (“Afghanistan” strain). …”
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Immediate results of aortic valve reconstruction using Ozaki method by В.М. Todurov, I.Yu. Mokryk, I.O. Aksionova, N.V. Ponych, C.M. Monastyrska, О.А. Yepanchintseva, I.M. Kuzmich, V.B. Demianchuk

“…Surgical technique is based on replacement of every single cusp of the diseased valve with neocusp trimmed using original Ozaki set from patients own pericardium treated with glutaraldehyde. …”
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Basis for the Age-related Decline in Intestinal Mucosal Immunity by Douglas L. Schmucker, Robert L. Owen, Robert Outenreath, Karine Thoreux

“…The elderly are characterized by mucosal immunosenescence and high rates of morbidity and mortality associated with infectious diseases of the intestinal tract. Little is known about how the differentiation of immunoglobulin A (IgA) plasma cells in Peyer's patches (PPs) and their subsequent homing to the small intestinal lamina propria (LP) is affected by aging. …”
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Levying evidence of the impact of Triphala in the mildly constipated human colon microbiota by Elizabeth Goya-Jorge, Pauline Bondue, Irma Gonza, Samiha Boutaleb, Caroline Douny, Marie-Louise Scippo, Joël Pincemail, Patrice Chiap, Jeoffrey Christyn de Ribaucourt, Fabienne Crahay, Véronique Delcenserie

“…Overall, these findings state some potential explanations for the usefulness of Triphala as a natural remedy for gastrointestinal diseases. However, it also raises concerns about some harmful effects of Triphala in the gut microbial ecosystem of people suffering from mild constipation.…”
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Comparison between ELISA and PCR for Detection of Epstein - Barr virus in children with acute cervical lymphadenitis by Nazim Khan, Neeraj Narayan Mathur, Sunil Kumar Singh Bhadouriya, Balvinder Singh Arora, Nidhi Chaudhary, Dhriti Khullar

“…The clinical features of acute Epstein-Barr virus infection overlap those of a variety of other infectious and non-infectious diseases so reliable laboratory tests are important to not only confirm but aid in the differential diagnosis. …”
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Blue elixir of youth and wellness: The multicomponent-multitarget paradigm of Curcuma caesia Roxb by Sabrina Burattini, Federico Gianfanti, Francesco Onesimo, Sabrina Donati Zeppa, Barbara Canonico, Mariele Montanari, Giovanna Panza, Daniele Lopez, Giosuè Annibalini, Fabiana Fanelli, Roberta Saltarelli, Michele Mari, Michele Retini, Riham Osman, Aghna Mariam, Matteo Micucci, Giovanni Caprioli, Agnese Santanatoglia, Deborah Agostini, Michela Battistelli

“…This process not only leads to visible signs of skin aging, such as wrinkles and elasticity loss, but also predisposes individuals to a spectrum of age-related diseases. Oxidative stress and inflammation are key events driving this phenomenon. …”
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Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with Sefaxersen by Michael L. McCaleb, Steven G. Hughes, Tamar R. Grossman, Ashley Frazer-Abel, Bill Jung, Lixuan Yin, Scott P. Henry, Brett P. Monia, Eugene Schneider, Richard Geary, Gary T. Brice

“…An over-active alternative complement pathway has been implicated in the pathophysiology of multiple diseases, including IgA nephropathy and geographic atrophy secondary to age related macular degeneration. …”
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Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1–infected women is associated with lower viral loads by Elina El-Badry, Luxiao Chen, Khader Ghneim, Ziyi Li, Kelsie Brooks, Jake Rhodes, Rafick Sekaly, William Kilembe, Susan Allen, Susan Allen, Susan Allen, Hao Wu, Eric Hunter, Eric Hunter

“…Sex differences play a role in the pathogenesis of a number of viral diseases. In HIV-1, several studies have reported that chronically infected women have significantly lower plasma viremia than men, although the exact mechanism by which this occurs has yet to be identified. …”
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Identification of fine antigenic epitopes of Tamdy virus glycoprotein Gn fragment and establishment of ELISA detection method by Yujiao Fu, Liping Liu, Beibei Zhang, Xiaoshan Chao, Junxia Jin, Ying Wang, Juntao Ding

“…TAMV is linked to febrile diseases, but its epidemiology and spillover risks are poorly understood, necessitating urgent molecular research and detection method development. …”
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Rhipicephalus simus ticks: new hosts for phleboviruses by Samuel Munalula Munjita, Benjamin Mubemba, John Tembo, Mathew Bates, Sody Munsaka, Ala Tabor

“…This study emphasizes the urgency of further research on the ecology, transmission dynamics, and pathogenic potential of LSK-ZM-102022 and related TBPVs, crucial for local and global preparedness against emerging tick-borne diseases.…”
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Association of Subclinical Hypothyroidism in Type 2 Diabetic Individuals by Noor ul ain, Sheikh Abdul Saeed, Muhammad sajid Abbas jaffri, Shazia Shakoor, Shah jabeen, Sana Kashif

“… Background: Diabetes Mellitus and Thyroid Disorders, both ranks as most prevalent endocrine diseases in clinical practice for last several years. …”
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Comparative Pharmacokinetic Studies of Four Ginsenosides in Rat Plasma by UPLC-MS/MS after Oral Administration of Panax quinquefolius-Acorus gramineus and Panax quinquefolius Extra... by Hailong Xie, Dongxue Wang, Wenjun Zhang, Xinjia Yan, Ying Zhao

“…Panax quinquefolius (PQ) and Acorus gramineus (AG) are drug target pairs in traditional Chinese medicine (TCM), which are used to treat age-related diseases. In the present study, we simultaneously determined the contents of four main bioactive ginsenosides (Rb1, Rb2, Rd, and Re) in rat plasma using an ultrahigh-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method. …”
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Towards a new spatial representation of bone remodeling by Jason M. Graham, Bruce P. Ayati, Prem S. Ramakrishnan, James A. Martin

“…Irregular bone remodeling is associated with a number of bone diseases such as osteoporosis and multiple myeloma. …”
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Short-term and long-term revision rates after lumbar spine discectomy versus laminectomy: a population-based cohort study by Yao-Chun Hsu, Feng-Chen Kao, Chang-Bi Wang, Yuan-Kun Tu, Pao-Hsin Liu

“…Background/objective Degenerative diseases of the lumbar spine were managed with discectomy or laminectomy. …”
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Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives by Domenica Lucia D’Antonio, Anna Zenoniani, Samia Umme, Adriano Piattelli, Maria Cristina Curia

“…<i>Fusobacterium nucleatum (Fn)</i>, an anaerobic Gram-negative bacterium primarily residing in the oral cavity, has garnered significant attention for its emerging role in several extra-oral human diseases and, lately, in pancreatic cancer progression and prognosis. …”
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Transcriptomics Analysis of Maize (<i>Zea mays</i> L.) in Response to the Infection by <i>Setosphaeria turcica</i> by Hui Jia, Pan Li, Bu Tao, Yuwei Liu, Zhihang Liu, Mengfang Zhu, He Zhou, Maocun Wang, Jingao Dong, Shouqin Gu, Xiaodong Gong

“…Northern corn leaf blight (NCLB), caused by <i>Setosphaeria turcica</i> (<i>S. turcica</i>), is one of the devastating foliar diseases of maize (<i>Zea mays</i>) in maize-producing regions globally. …”
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