Effect of attenueted parapoxvirus ovis on levels of some serum cytokines and antibody response in sheep by Kamil Atlı, Atilla Şimşek

“…<b>Aim:</b> Parapoxvirus ovis (ORFV) infection is one of important contagious viral diseases of small ruminants. The aim of this study was to determine the concentration of cytokine and neutralizing antibody in blood serum of sheep that were carried out attenuated orf virus vaccine strain.…”
Get full text

Scales to Assess Knowledge, Motivation, and Self-Efficacy for HIV PrEP in Colombian MSM: PrEP-COL Study by Héctor F. Mueses-Marín, Beatriz Alvarado-Llano, Julián Torres-Isasiga, Pilar Camargo-Plazas, Maria C. Bolívar-Rocha, Ximena Galindo-Orrego, Jorge L. Martínez-Cajas

Get full text

Cilostazol Combats Lipopolysaccharide-Induced Hippocampal Injury in Rats: Role of AKT/GSK3β/CREB Curbing Neuroinflammation by Doaa Abou El-ezz, Waleed Aldahmash, Tuba Esatbeyoglu, Sherif M. Afifi, Marawan Abd Elbaset

“…Cilostazol may hold promise as a therapeutic agent for neuroinflammatory conditions associated with neurodegenerative diseases.…”
Get full text

Enhancing Mesenchymal Stromal Cell Immunomodulation for Treating Conditions Influenced by the Immune System by Bella S. Guerrouahen, Heba Sidahmed, Asma Al Sulaiti, Moza Al Khulaifi, Chiara Cugno

“…Thus, immunosuppressive treatment with MSCs has been proposed as a potential therapeutic alternative for conditions in which the immune system cells influence outcomes, such as inflammatory and autoimmune diseases. The precise mechanism by which MSCs affect functions of most immune effector cells is not completely understood but involves direct contact with immune cells, soluble mediators, and local microenvironmental factors. …”
Get full text

Promising horizons in achondroplasia along with the development of new drugs by Keiichi Ozono, Takuo Kubota, Toshimi Michigami

Get full text

Automated karyogram analysis for early detection of genetic and neurodegenerative disorders: a hybrid machine learning approach by Sumaira Tabassum, M. Jawad Khan, Javaid Iqbal, Asim Waris, M. Adeel Ijaz

“…Anomalous chromosomes are the cause of genetic diseases such as cancer, Alzheimer's, Parkinson's, epilepsy, and autism. …”
Get full text

Environmental and geographic study of betanin accumulation in promising red beet accessions from the VIR collection by D. V. Sokolova

“…The negative impact of these factors would smooth down the crop’s varietal polymorphism. Diseases and insect pests have led to slowing and stopping the accumulation of betanin. …”
Get full text

HDL Subclass Distribution Shifts with Increasing Central Adiposity by Nicholas J. Woudberg, Sandrine Lecour, Julia H. Goedecke

Get full text

Unraveling the insomnia puzzle: sleep reactivity, attention deficit hyperactivity symptoms, and insomnia severity in ADHD Patients by Hilal Uygur

“…This study aimed to investigate the relationship between sleep reactivity, attention deficit hyperactivity symptoms, and the severity of insomnia in adults with ADHD.MethodsThis study included 61 adults with ADHD with no comorbid psychiatric or medical diseases and 61 adult healthy controls (HCs) matched for age, sex, body mass index, and years of education. …”
Get full text

Local Hyperthermia Combined With Imiquimod Cleared Recalcitrant and Extensive Warts in a Patient With Systemic Lupus Erythematosus by Wang GH, Wang YB, Cheng YA, Chen HD, Gao XH, Qi RQ

“…Gai-Hua Wang,1,&ast; Yang-Bin Wang,2,3,&ast; Yue-Ai Cheng,1 Hong-Duo Chen,2,3 Xing-Hua Gao,2,3 Rui-Qun Qi2,3 1Institute of Dermatology, Taiyuan City Centre Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, People’s Republic of China; 2Department of Dermatology, the First Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of China; 3Key Laboratory of Immunodermatology, Ministry of Education and NHC; National Joint Engineering Research Center for Theranostics of Immunological Skin Diseases, Shenyang, Liaoning Province, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Rui-Qun Qi, Department of Dermatology, the First Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of China, Email xiaoqiliumin@163.com Yue-Ai Cheng, Institute of Dermatology, Taiyuan City Centre Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, People’s Republic of China, Email 172915043@qq.comAbstract: Viral warts, a common dermatological condition caused by human papillomavirus infection (HPV) infection, present a particular challenge for systemic lupus erythematosus (SLE) patients due to their compromised immunity, which increases the susceptibility to HPV infection and complicates treatment efforts. …”
Get full text

False Alarm Reduction in Self-Care by Personalized Automatic Detection of ECG Electrode Cable Interchanges by Jocelyne Fayn, Paul Rubel

“…False alarm reduction is an important challenge in self-care, whereas one of the most important false alarm causes in the cardiology domain is electrodes misplacements in ECG recordings, the main investigations to perform for early and pervasive detection of cardiovascular diseases. In this context, we present and assess a new method for electrode reversals identification for Mason-Likar based 3D ECG recording systems which are especially convenient to use in self-care and allow to achieve, as previously reported, high computerized ischemia detection accuracy. …”
Get full text

Morroniside Ameliorates Endotoxin-Induced Uveitis by Regulating the M1/M2 Polarization Balance of Macrophages by Wenjie Li, Lin Liu, Ziwei Zhang, Hong Lu

“…Inflammation is closely associated with the pathogenesis of various ocular diseases. Uveitis is a condition characterized by the inflammation of the uvea and ocular tissues that causes extreme pain, decreases visual acuity, and may eventually lead to blindness. …”
Get full text

Prevalence of Plasmid-Mediated Quinolone Resistance Determinants and OqxAB Efflux Pumps among Extended-Spectrum β-Lactamase Producing Klebsiella pneumoniae Isolated from Patients w... by Mehdi Goudarzi, Mehdi Azad, Sima Sadat Seyedjavadi

Get full text

Bridging Molecular Docking to Molecular Dynamics to Enlighten Recognition Processes of Tailored D-A/D-A-D Types' AIEgens with HSA/BSA by Harun Nalçakan, Gülbin Kurtay

“…In this scope, we performed a detailed molecular dock-ing study of Donor (D)-Acceptor (A) or D-A-D type luminogens with two blood proteins; namely bovine serum albumin (BSA) and human serum albumin (HSA), which appeared as robust carriers of several pharmaceuticals against preliminary cancer diseases. Our results revealed that the binding scores of the Dn-An or Dn-An-Dn:BSA complexes ranged from -8.5 to -11.7 kcal/mol while Dn-An or Dn-An-Dn:HSA complexes showed scores varying from -8.4 to -10.5 kcal/mol. …”
Get full text

Primary dysmenorrhea pain profile among Brazilian women. Case-control study by Flávia Rezende Moura Mesquita Rafael, Natalia Oliveira Bertolini, Samuel Silva, Renato Carvalho Vilella1

“…BACKGROUND AND OBJECTIVES: Primary dysmenorrhea (PD) is defined as lower abdominal pain occurring before or during menstruation, unrelated to other diseases. Existing studies investigating potential risk factors for PD development and its incidence in various groups have been fragmented, controversial, or overly broad, posing challenges for analysis. …”
Get full text

Association Between ABO Blood Groups and Malaria Severity in a Regional Referral Hospital in Jayapura Papua, Indonesia by Andreas Pekey, Leonard Nainggolan, Cosphiadi Irawan, Kuntjoro Harimurti

Get full text

Effects of Pickleball Intervention on the Self-Esteem and Symptoms of Patients with Schizophrenia by Tsai-Chieh Chien, Chao-Chien Chen

“…<i>Background:</i> Schizophrenia is classified by the World Health Organization (WHO) as one of the top ten diseases contributing to the global medical economic burden. …”
Get full text

Asymptotic analysis of mathematical model describing a new treatment of breast cancer using AZD9496 and palbociclib by Ophir Nave, Ophir Nave

“…IntroductionCancer is a collective name for a group of diseases consisting of dozens of different types of malignant tumors, characterized by rapid and uncontrolled proliferation of cells in the body. …”
Get full text

Rational selection of TbpB variants yields a bivalent vaccine with broad coverage against Neisseria gonorrhoeae by Jamie E. Fegan, Epshita A. Islam, David M. Curran, Dixon Ng, Natalie Y. T. Au, Elissa G. Currie, Joseph J. Zeppa, Jessica Lam, Anthony B. Schryvers, Trevor F. Moraes, Scott D. Gray-Owen

Get full text

Wolbachia, Spiroplasma, and Rickettsia symbiotic bacteria in aphids (Aphidoidea) by D. A. Romanov, I. A. Zakharov, E. V. Shaikevich

Get full text