Integrated and streamlined microfluidic device for molecular diagnosis of pathogen through direct PCR amplification by Dohwan Lee, Tae Seok Seo

“…Background: Polymerase chain reaction (PCR) is a gold-standard method widely acknowledged for offering precise and rapid analysis of genetic material, particularly having a crucial role in detecting pathogens and diagnosing infectious diseases. However, the complexity of the PCR process (including nucleic acid extraction/purification, amplification, and amplicon detection) hinders its widespread adoption in point-of-care testing, where simplicity and rapidity are essential for practical use. …”
Get full text

Symptoms affecting patient’s intake of food with lymphoma in outpatient chemotherapy by Andressa Madalozo Laffitte, Carolina Lane Alves Farias, Jessica Wszolek

“…This cancer had the highest increase in incidence among oncohematological diseases. The objective of the study was evaluate the pos- sible gastrointestinal symptoms presented by the patient during treatment and relates them to food intake and nutritional status. …”
Get full text

Boosting Therapeutic Effect of Turmeric, Coffee, and Chili Extracts Through Experimental Design and Encapsulation as Nanostructured Lipid Carriers for Novel Heath Supplements by Pratchaya Tipduangta, Phennapha Saokham, Jutamas Jiaranaikulwanitch, Siriporn Okonogi, Chadarat Ampasavate, Kanokwan Kiattisin

“…This study investigates the potential synergistic effects of extracts from <i>Curcuma longa</i> (turmeric), <i>Coffea arabica</i> (Arabica coffee beans), and <i>Capsicum annuum</i> (chili peppers) in reducing oxidative stress and inflammation, which are associated with metabolic disorders such as obesity, diabetes, and cardiovascular diseases. Using a systematic design of experiment (DoE) optimization approach, an optimal extract ratio of 1:3:4 (turmeric: coffee: chili) was identified. …”
Get full text

Rapid growing mass of the mandible due to an oral metastasis of thymoma: Case report of an extremely rare localization and review of published cases by Francesco Scilla, Cosimo Rupe, Gioele Gioco, Luca Raffaelli, Filippo Lococo, Ciro Mazzarella, Guido Rindi, Romeo Patini, Carlo Lajolo

“…The oral screening of patients with thymic tumors could be useful, considering the relationship between these diseases and oral disorders.…”
Get full text

Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia by Aleksandra Savić, Ana Alimpić Aradski, Jelena Živković, Katarina Šavikin, Snežana Jarić, Petar D. Marin, Sonja Duletić-Laušević

“…The performed analyses have revealed that fruits of traditional Serbian pear varieties are rich in bioactive components and could be used as functional food and for possible nutraceutical applications, to prevent diseases induced by oxidative stress.…”
Get full text

Maternal Fructose Intake Induces Insulin Resistance and Oxidative Stress in Male, but Not Female, Offspring by Lourdes Rodríguez, Paola Otero, María I. Panadero, Silvia Rodrigo, Juan J. Álvarez-Millán, Carlos Bocos

“…Fructose intake from added sugars correlates with the epidemic rise in metabolic syndrome and cardiovascular diseases. However, consumption of beverages containing fructose is allowed during gestation. …”
Get full text

Risk Prediction Using Genome-Wide Association Studies on Type 2 Diabetes by Sungkyoung Choi, Sunghwan Bae, Taesung Park

“…However, most variants discovered by GWASs have been reported to have very small effect sizes on complex human diseases, which has been a big hurdle in building risk prediction models. …”
Get full text

Study of Zuojin Pill in Treating Chronic Atrophic Gastritis by UPLC-Q-TOF/MS Based on Serum and Urine Metabolomics Combined with Network Pharmacology by Shihua Wu, Xing Chen, Honghong Liu, Ruilin Wang, Jianyu Li, Jianxia Wen, Tao Yang, Ying Wei, Sichen Ren, Shizhang Wei, Manyi Jing, Haotian Li, Min Wang, Houlin Xia, Yanling Zhao

“…Zuojin Pill (ZJP) is widely used for the treatment of gastrointestinal diseases, while its specific mechanism has not been systematically investigated. …”
Get full text

Interleukin-17: Potential Target for Chronic Wounds by Yasmin Hadian, Michelle D. Bagood, Sara E. Dahle, Apra Sood, R. Rivkah Isseroff

“…Since the interleukin-17 family has been implicated as a group of proinflammatory cytokines in immune-mediated diseases in the gut and connective tissue, as well as inflammatory skin conditions, we consider here if it may contribute to the pathogenesis of chronic wounds. …”
Get full text

Advanced Lasers and Their Applications in Dentistry by Olivia Lili Zhang, Iris Xiaoxue Yin, Ollie Yiru Yu, Kenneth Luk, John Yun Niu, Chun Hung Chu

“…High-power and low-power lasers are used in both nonsurgical and surgical therapies to treat periodontal and peri-implant diseases, oral mucosa conditions, and even cancer based on their specific properties. …”
Get full text

Factors influencing street-vended foods quality and safety in developing countries: a review by O. A. Bassitou Koumassa, Romaric Ouétchéhou, Mathias Hounsou, Oscar Zannou, D. Sylvain Dabadé

“…However, they are among the main transmission routes for foodborne diseases. This study aimed at carrying out an in-depth analysis of street foods in developing countries, focusing on factors affecting their quality and safety. …”
Get full text

Association between Sleep Habits and Metabolically Healthy Obesity in Adults: A Cross-Sectional Study by Thirumagal Kanagasabai, Ramandeep Dhanoa, Jennifer L. Kuk, Chris I. Ardern

“…Higher body mass index (BMI) increases the risk of cardiometabolic diseases, but nearly a third of the people living with obesity (BMI: ≥30 kg/m2) are metabolically healthy (MHO). …”
Get full text

Methimazole Inhibits the Expression of GFAP and the Migration of Astrocyte in Scratched Wound Model In Vitro by Lina Zhao, Xianyu Zhang, Chunhai Zhang

“…While scar formation plays a very important role in wound healing and prevents further bleeding by forming a physical barrier, it is also one of key features of CNS injury, resulting in glial scar formation (astrogliosis), which is closely related to treatment resistant epilepsy, chronic pain, and other devastating diseases. Therefore, slowing the astrocytic activation process may give a time window of axonal growth after the CNS injury. …”
Get full text

Eyes that Do Not Meet the Eligibility Criteria of Clinical Trials on Age-Related Macular Degeneration: Proportion of the Real-World Patient Population and Reasons for Exclusion by Jae Hui Kim, Jong Woo Kim, Chul Gu Kim

“…The second most common reason was a fovea-involving scar or fibrosis in typical neovascular AMD, subretinal hemorrhage in PCV, and other vascular diseases affecting the retina in type 3 neovascularization. …”
Get full text

Antiallergic Effect of the Alpha-Cyclodextrin Moringin Complex in Rat Basophilic Leukaemia (RBL-2H3) Cell Line by Ebtisam Yousef A. Alnakeeb, Ahmad Faizal Abdull Razis, Kim Wei Chan, Chau Ling Tham, Yee Han Chan, Anwar Salm Kalifa Kafo, Nuzul Noorahya Jambari, Patrick Rollin, Florence Djedaini-Pilard

“…Allergic diseases (ADs) are a major concern when it comes to public well-being. …”
Get full text

Design and experimental validation of the action of small molecule-based inhibitors of the FADD protein by N. V. Ivanisenko, L. Hillert, V. A. Ivanisenko, I. N. Lavrik

“…The search for the inhibitors that would block the interactions of FA DD with the other core proteins of the DISC is essential for the studies of the structure and function of this complex, investigation of the apoptosis mechanisms and development of new treatments for neurodegenerative diseases. In the course of this work, the screening for small inhibitors in silico that selectively interact with DED has been performed. …”
Get full text

Farmer’s Knowledge on Thaumatotibia Leucotreta (Meyrick) an Economic Pest of Avocado Production in Tanzania by Juliana G. Shikoshi, Angela G. Mkindi, Patrick A. Ndakidemi, Ernest R. Mbega, Kelvin M. Mtei

“…Furthermore, farmers reported that diseases, poor marketing environment and premature fruit dropping were the main challenges faced in avocado production. …”
Get full text

A fungus-eat-fungus world: Digitopodium, with particular reference to mycoparasites of the coffee leaf rust, Hemileia vastatrix by Adans A. Colmán, Harry C. Evans, Sara S. Salcedo-Sarmiento, Uwe Braun, Kifle Belachew-Bekele, Robert W. Barreto

“…Abstract Digitopodium hemileiae was described originally in 1930 as Cladosporium hemileiae; growing as a mycoparasite of the coffee leaf rust (CLR), Hemileia vastatrix, in a sample of diseased leaves of Coffea canephora collected in the Democratic Republic of Congo. …”
Get full text

Antimicrobial Characterization of Erythorbyl Laurate for Practical Applications in Food and Cosmetics by Jin-Woo Kim, Hyunjong Yu, Kyung-Min Park, Pahn-Shick Chang

“…In this study, antimicrobial spectrum of erythorbyl laurate (EL) against bacteria and fungi, leading to food-borne and infectious skin diseases, was evaluated for its practical applications in food and cosmetics. …”
Get full text

The use of the model organism Caenorhabditis elegans in the investigation of the adverse effects of electronic cigarettes by Kamila Melnikov, Alžbeta Kaiglová, Soňa Kucharíková

“…The use of tobacco products is one of the most preventable risk factors for mortality from a variety of diseases, including cardiovascular, infectious, respiratory, and neoplastic conditions. …”
Get full text