Comparative evaluation of four exome enrichment solutions in 2024: Agilent, Roche, Vazyme and Nanodigmbio by Vera Belova, Iuliia Vasiliadis, Zhanna Repinskaia, Alina Samitova, Anna Shmitko, Natalya Ponikarovskaya, Oleg Suchalko, Valery Cheranev, Shatalov Peter, Shegai Peter, Kaprin Andrey, Denis Rebrikov, Dmitriy Korostin

“…Abstract Whole exome sequencing (WES) is essential for identifying genetic variants linked to diseases. This study compares available to date four exome enrichment kits: Agilent SureSelect Human All Exon v8, Roche KAPA HyperExome, Vazyme VAHTS Target Capture Core Exome Panel, and Nanodigmbio NEXome Plus Panel v1. …”
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Drug-Induced Liver Injuries (Clinical Guidelines for Physicians) by Vladimir T. Ivashkin, Andrey Yu. Baranovsky, Karina L. Raikhelson, Lyudmila K. Palgova, Marina V. Maevskaya, Elina A. Kondrashina, Natalya V. Marchenko, Tatyana P. Nekrasova, Igor G. Nikitin

“…The clinical and morphological forms (phenotypes) of DILI are described. The diseases that are included into the differential diagnosis of DILI, as well as the principles of its implementation, are given. …”
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Interaction of Pubertal Development and Metabolic Control in Adolescents with Type 1 Diabetes Mellitus by M. Plamper, B. Gohlke, J. Woelfle, K. Konrad, T. Rohrer, S. Hofer, W. Bonfig, K. Fink, R. W. Holl

“…Exclusion criteria: other significant chronic diseases and medications, T1DM duration less than three months, and initial BMI < 3rd or >97th percentile. …”
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Phenolic Compounds from Apples: Reviewing their Occurrence, Absorption, Bioavailability, Processing, and Antioxidant Activity – a Review by Małgorzata Starowicz, Bohdan Achrem–Achremowicz, Mariusz K. Piskuła, Henryk Zieliński

“…Some epidemiological studies have confirmed the protective effects of apples against chronic diseases, which can be linked to the high content of phenolics in plant tissues and their bioavailability. …”
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Characterization of the third molars eruption in the Oral Planet dental office. Ecuador, 2022 by Emely Maily Pluas Castro, Jaime Fernando Armijos Armijos Moreta, Silvia Marisol Gavilánez Villamarín

“…<p><strong>Background:</strong> third molars constitute a dental organ of interest to the scientific community since they present various morphologies, they tend to erupt in different ways and constitute a predisposing factor for the oral diseases appearance.<br /><strong>Objective:</strong> to characterize the third molars eruption of the patients from the Oral Planet clinic, in Ecuador.…”
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Exploring brain perfusion in dogs with meningoencephalitis of unknown origin: A promising role for arterial spin labeling imaging by Léa Arti, Kirsten Gnirs, Stella Papageorgiou, Yannick Ruel, Albert Agoulon, Nathalie Boddaert, Hugues Gaillot

“…Preferential lesion localization in ON and brainstem resembled findings in the central nervous system of human patients with inflammatory demyelinating diseases. Future studies with histopathological confirmation are needed to better characterize the benefits of ASL in the different subtypes of non‐infectious encephalomyelitis in dogs.…”
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Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS by Weiyi Cao, Hezhi Yao, Zhenzhen Qian, Yi Wu, Shuge Wang, Rui Li, Rui Gao

“…Clinically, salvianolate injection and aspirin are commonly combined to treat coronary heart diseases in patients with stable angina. To support clinical studies on drug-drug interactions (DDIs) between salvianolate injection and aspirin, a rapid and sensitive UPLC-MS/MS method for the simultaneous determination of aspirin (acetylsalicylic acid), its metabolite salicylic acid, and salvianolic acid B in human plasma was developed. …”
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Schwann Cell‐Specific Ablation of Beclin 1 Impairs Myelination and Leads to Motor and Sensory Neuropathy in Mice by Lisa Gambarotto, Loris Russo, Silvia Bresolin, Luca Persano, Rachele D'Amore, Giulia Ronchi, Federica Zen, Luisa Muratori, Alice Cani, Samuele Negro, Aram Megighian, Sonia Calabrò, Paola Braghetta, Dario Bizzotto, Matilde Cescon

“…Remarkably, the dysregulation in endosomal trafficking is emerging as a pathophysiological mechanism underlying peripheral neuropathies, such as demyelinating Charcot‐Marie‐Tooth (CMT) diseases. By knocking out Beclin 1 in SCs here a novel mouse model (Becn1 cKO) is generated, developing a severe and progressive neuropathy, accompanied by involuntary tremors, body weight loss, and premature death. …”
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Selenium-enriched oolong tea (Camellia sinensis) extract exerts anti-inflammatory potential via targeting NF-κB and MAPK pathways in macrophages by Qi Wang, Juqing Huang, Yafeng Zheng, Xuefang Guan, Chenchun Lai, Huiying Gao, Chi-Tang Ho, Bin Lin

“…Collectively, our results indicated that Se-TE may have the potential to be used as a novel food ingredient for the development of various anti-inflammatory foods and the treatment and prevention of chronic inflammation-related diseases.…”
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Food Addiction, Saturated Fat Intake, and Body Mass Index in Peruvian Adults: A Cross-Sectional Survey by Dulce E. Lopez-Lopez, Ivett K. Saavedra-Roman, Yaquelin E. Calizaya-Milla, Jacksaint Saintila

“…Background. Cardiovascular diseases (CVDs) constitute one of the main public health problems and represent a greater risk of mortality and morbidity for the world population. …”
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Exosomes Derived from Stem Cells from the Apical Papilla Promote Dentine-Pulp Complex Regeneration by Inducing Specific Dentinogenesis by Xueying Zhuang, Lingli Ji, Huan Jiang, Yao Liu, Xuemei Liu, Jing Bi, Weidong Zhao, Zhenjiang Ding, Xu Chen

“…Regenerative endodontic procedures (REPs) are a new option for the treatment of dental pulp or periapical diseases in permanent teeth with open apices. Histologically, the new tissues formed in the root canal after REPs are mainly cementum- or bone-like mineralised tissues, but not the real dentine-pulp complex. …”
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Operative Versus Nonoperative Management of Pyogenic Flexor Tenosynovitis: An Analysis of the National Readmissions Database by Justin D. Sawyer, MD, Justin Davis, MD, Steven Scaife, MS, Michael W. Neumeister, MD, Timothy H.F. Daugherty, MD

“…Methods: International Classification of Diseases, Tenth Revision codes were used to identify patients admitted with PFT from the National Readmissions Database for the years 2016–2019. …”
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Antibacterial and Antifungal Activities of the Leaf Exudate of Aloe megalacantha Baker by Demoze Asmerom, Tesfay Haile Kalay, Gebrehiwot Gebremedhin Tafere

“…Infectious diseases caused by fungi and bacteria are among the major causes of illness and death worldwide. …”
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The Regulation between CD4+CXCR5+ Follicular Helper T (Tfh) Cells and CD19+CD24hiCD38hi Regulatory B (Breg) Cells in Gastric Cancer by Ying Zhang, Jun Wu, Haibo Zhang, Chen Wu

“…T follicular helper (Tfh) cells and regulatory B (Breg) cells are reported to play essential roles in humoral immunity, especially in inflammation, autoimmune diseases, and cancer. Hence, we sought to investigate the involvement of CXCR5+CD4+ Tfh cells and CD19+CD24hiCD38hi Breg cells in gastric cancer. …”
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Ethnobotanical survey of medicinal and aromatic plants used by the population of Settat Province, Morocco by Manal Lahyaoui, Nadia Dakka, Naoual El Menyiy, Mansour Sobeh, Pakhrur Razi, Khang Wen Goh, Yaser Mohammed Al-Worafi, Muhammad Junaid Farrukh, Abdelhakim Bouyahya

“…The results highlighted the primary ailments treated with these plants, such as diabetes, gastrointestinal disorders, cardiovascular diseases, oral conditions, cancers, insomnia, and stress. …”
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Characterization of a Complex Mixture of Immunomodulator Peptides Obtained from Autologous Urine by Alberto Fragoso, Mérida Pedraza-Jiménez, Laura Espinoza-González, María Luisa Ceja-Mendoza, Hugo Sánchez-Mercado, Gloria Robles-Pérez, Julio Granados, Emilio Medina-Rivero

“…Here, we characterized the peptide profile of three extracts of an immunomodulator obtained from the urine of different volunteers suffering from three different diseases (i.e., allergic rhinitis, rheumatoid arthritis, and chronic rhinopharyngitis), using size exclusion chromatography (SEC) and mass spectrometry (MS). …”
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Evaluation of Iron Deficiency Anemia Frequency as a Risk Factor in Glaucoma by Penpe Gul Firat, Ersan Ersin Demirel, Seyhan Dikci, Irfan Kuku, Oguzhan Genc

“…Also it is considered to be a risk factor for many diseases. The study demonstrates the iron deficiency anemia frequency in glaucoma patients and compares with the normal subjects. …”
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Epidemiological and clinical variables in pediatric patients hospitalized for urinary tract infection by Isabel María Vallina López, Rolando Rodríguez Puga, Yasnier Dueñas Rodríguez, Yoánderson Pérez Díaz, María Emilia Navarro Huertas, María Francisca Garcés Raventós

“…<p><strong>Foundation</strong>: urinary tract infection is one of the most common diseases in children and presents with non-specific symptoms, especially in younger children, in which the most important sign is fever.…”
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Phenolic Content and Antioxidant, Antihyperlipidemic, and Antidiabetogenic Effects of Opuntia dillenii Seed Oil by Mohamed Bouhrim, Nour Elhouda Daoudi, Hayat Ouassou, Amina Benoutman, El Hassania Loukili, Abderrahim Ziyyat, Hassane Mekhfi, Abdelkhaleq Legssyer, Mohammed Aziz, Mohamed Bnouham

“…Haw. is a medicinal plant that is widely used by the Moroccan population to treat many diseases, thanks to its richness in bioactive molecules. …”
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The Clinical and Pathological Presentation of Thyroid Nodules in Children and the Comparison with Adult Population: Experience of a Single Institution by Tamas Solymosi, Gyula Lukacs Toth, Laszlo Budai, Istvan Gal

“…The proportion of nodular goiters (22.8% versus 39.3%), the ratio of surgically treated nodules (33.2% versus 15.2%), and the proportion of malignant nodules (4.3% versus 2.1%) among diseased patients differed significantly between the two groups (younger versus adult). …”
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