O-GlcNAcylated FTO promotes m6A modification of SOX4 to enhance MDS/AML cell proliferation by Junjie Gou, Jingjing Bi, Kexin Wang, Lei Lei, Yanli Feng, Zengqi Tan, Jiaojiao Gao, Yanan Song, Enci Kang, Feng Guan, Xiang Li

“…In conclusion, our study highlights the crucial role of FTO O-GlcNAcylation in RNA m6A methylation and the progression of MDS/AML, thereby providing a potential therapeutic avenue for these formidable diseases.…”
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Potential Pitfalls of the Humanized Mice in Modeling Sepsis by Krzysztof Laudanski, Michael Stentz, Matthew DiMeglio, William Furey, Toby Steinberg, Arpit Patel

“…Humanized mice are a state-of-the-art tool used to study several diseases, helping to close the gap between mice and human immunology. …”
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KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition by Deniz Gökbuget, Liana Goehring, Ryan M. Boileau, Kayla Lenshoek, Tony T. Huang, Robert Blelloch

“…Our findings reveal KMT2C/D-dependent H3K4me1 as a key regulator of RT and replication initiation, a role that likely impacts diseases associated with KMT2C/D mutations.…”
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Motion-tolerant 3D volumetric multimodality microscopy imaging of human skin with subcellular resolution and extended field-of-view by Zhenguo Wu, Yunxian Tian, Jianhua Zhao, Yimei Huang, Harvey Lui, Sunil Kalia, Haishan Zeng

“…In vivo noninvasive 3D volumetric imaging with multi-contrast, high resolution, a large field-of-view (FOV), and no-motion artifacts is crucial for studying skin biology and diagnosing/evaluating diseases. Traditionally high-resolution in vivo skin microscopy methods capture images in the en-face (xy) plane parallel to the skin surface but are affected by involuntary motion, particularly during large-area volumetric data acquisition using xy-z mosaicking. …”
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Lateral mass intrapedicular screw fixation: A radiological evaluation of screw pullout strength by Kota Kojima, Hiroaki Kanbe, Kenichiro Fukui, Takahiro Endo, Yasuyuki Fukui, Masayuki Ishikawa, Shunji Asamoto

“…Background: Lateral mass intrapedicular screw (LMIS) fixation was introduced in 2021 as a safe and simple alternative method for the fixation of the subaxial cervical spine in the treatment of various cervical spine diseases. The purpose of this study was to evaluate and compare the screw pullout strength of this new technique to the trajectories of two other major methods, the transpedicular screw (TPS) and lateral mass screw (LMS) methods. …”
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Nurses’ Knowledge Regarding Cardiac Catheterization at General Hospital in Rania City by Bayan O. Sharif, Shara H. Salih, Niga A. Sailh, Bahar I. Salim

“…Coronary angiography is that invasive procedure which assumed as the golden standard for the diagnosis, estimation, and curing of heart diseases. There is a shortage of research of undergraduate students. …”
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The Segmental Morphometric Properties of the Horse Cervical Spinal Cord: A Study of Cadaver by Sadullah Bahar, Durmus Bolat, Muhammet Lutfi Selcuk

“…Although the cervical spinal cord (CSC) of the horse has particular importance in diseases of CNS, there is very little information about its segmental morphometry. …”
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Activation of Vitamin D Regulates Response of Human Bronchial Epithelial Cells to Aspergillus fumigatus in an Autocrine Fashion by Pei Li, Ting Wu, Xin Su, Yi Shi

“…Aspergillus fumigatus (A. fumigatus) is one of the most common fungi to cause diseases in humans. Recent evidence has demonstrated that airway epithelial cells play an important role in combating A. fumigatus through inflammatory responses. …”
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The morphofunctional and biochemical characteristics of opisthorchiasis-associated cholangiocarcinoma in a Syrian hamster model by G. A. Maksimova, M. Y. Pakharukova, E. V. Kashina, N. A. Zhukova, M. N. Lvova, M. V. Khvostov, D. S. Baev, A. V. Katokhin, T. G. Tolstikova, V. A. Mordvinov

“…Cholangiocarcinoma, or bile duct cancer, ranks second among oncological diseases of the liver. There is a strong association between bile duct cancer and parasitic infestation of the liver caused by trematodes in the family Opisthorchiidae. …”
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Post-harvest Fungal Infection in Arabica Coffee Beans (Coffea arabica Linnaeus) in the Coffee Center of West Sumatra Province, Indonesia by Martinius Martinius, Aziz Fauzi, Zurai Resti

“…The research was carried out at the Phytopathology Laboratory of Plant Pests and Diseases Department and the Seed Technology Laboratory of Agronomy Department, Agriculture Faculty, Universitas Andalas, Padang, from June to August 2021. …”
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Wharton’s Jelly-Derived Mesenchymal Stem Cells with High Aurora Kinase A Expression Show Improved Proliferation, Migration, and Therapeutic Potential by Sun Jeong Kim, Sang Eon Park, Jang Bin Jeong, Shin Ji Oh, Alee Choi, Yun Hee Kim, Suk-joo Choi, Soo-young Oh, Gyu Ha Ryu, Hong Bae Jeon, Jong Wook Chang

“…In particular, human WJ-MSCs with high expression of AURKA might have therapeutic efficacy against muscle diseases, such as Duchenne muscular dystrophy (DMD).…”
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From lab to real-life: A three-stage validation of wearable technology for stress monitoring by Basil A. Darwish, Shafiq Ul Rehman, Ibrahim Sadek, Nancy M. Salem, Ghada Kareem, Lamees N. Mahmoud

“…Stress negatively impacts health, contributing to hypertension, cardiovascular diseases, and immune dysfunction. While conventional diagnostic methods, such as self-reported questionnaires and basic physiological measurements, often lack the objectivity and precision needed for effective stress management, wearable devices present a promising avenue for early stress detection and management. …”
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Modified screening and management strategies for chronic rhinosinusitis in hematologic patients receiving hematopoietic stem cell transplantation by Yen-Hui Lee, Chih-Feng Lin, Te-Huei Yeh, Huai-Hsuan Huang, Yi-Tsen Lin

“…Methods: We conducted a nested case-control study in a retrospective cohort of hematologic patients receiving HSCT from April 2011 to April 2021 and collected data on demographics, smoking/atopic status, hematological diseases, and features of rhinosinusitis for analysis. …”
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Cytoskeletal Vimentin Directs Cell‐Cell Transmission of Hepatitis C Virus by Yifan Xing, Zeyu Wen, Jie Mei, Xinyi Huang, Shuangshuang Zhao, Jin Zhong, Yaming Jiu

“…Abstract Hepatitis C virus (HCV) is a major human pathogen causing liver diseases. Although direct‐acting antiviral agents effectively inhibit HCV infection, cell–cell transmission remains a critical venue for HCV persistence in vivo. …”
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Labeling tumor-associated extracellular vesicles with antibody-DNA conjugates for quantitative analysis by Xiao Du, Xiao Du, Xiao Du, Hongxiu Li, Hongxiu Li, Hongxiu Li, Shiyi Shen, Shiyi Shen, Shiyi Shen, Chao Tian, Chao Tian, Chao Tian, Xiaohuan Cao, Xiaohuan Cao, Xiaohuan Cao, Xingang Xu, Nan Xu, Shuling Wang, Shuling Wang, Shuling Wang, Qingchang Tian, Qingchang Tian, Qingchang Tian

“…Antibody-DNA conjugates were used to recognize the epithelial cell adhesion molecule (EpCAM) antigen on the TAE surface and quantify the antigen using qPCR for cancer analysis.DiscussionThis method proposed a new quantitative detection approach for TAEs, which aim to identify specific EV-associated markers for diagnostic or therapeutic, this method could inspire a new idea for tumor diagnosis and detection of other diseases.…”
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Comparative Transcriptome Analyses of Resistant and Susceptible Near-Isogenic Wheat Lines following Inoculation with Blumeria graminis f. sp. tritici by Piyi Xing, Xueying Zhang, Yinguang Bao, Yuhai Wang, Honggang Wang, Xingfeng Li

“…Powdery mildew is one of the most important diseases of wheat. In this study, the leaf RNA samples of wheat NILs carrying powdery mildew resistant and susceptible Pm2 alleles (L031 and Chancellor) and its F1 hybrid at two time points (16 h and 96 h postinoculation) were used for RNA-seq analysis. …”
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Thermosensitive Chitosan-β-Glycerophosphate Hydrogels as Targeted Drug Delivery Systems: An Overview on Preparation and Their Applications by Pouria Rahmanian-Devin, Vafa Baradaran Rahimi, Vahid Reza Askari

“…Hydrogels are used in many drug delivery systems and diseases, including nasal drug delivery, vaginal drug delivery, wound healing, peritoneal adhesion, ophthalmic drug delivery, tissue engineering, and peptide and protein delivery. …”
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Transcutaneous Electrical Acupoint Stimulation in Early Life Changes Synaptic Plasticity and Improves Symptoms in a Valproic Acid-Induced Rat Model of Autism by Xiaoxi Wang, Rui Ding, Yayue Song, Juan Wang, Chen Zhang, Songping Han, Jisheng Han, Rong Zhang

“…Transcutaneous electrical acupoint stimulation (TEAS) is a noninvasive technique derived from acupuncture and has been shown to have similar therapeutic effects in many diseases. Valproic acid- (VPA-) induced ASD is a known model of ASD in rats. …”
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Reported Diabetes Mellitus Prevalence Rates in the Colombia Healthcare System from 2009 to 2012: Analysis by Regions Using Data of the Official Information Sources by Noël C. Barengo, Diana Carolina Tamayo

“…Information on number of patients treated for DM was obtained by the Integral Information System of Social Protection (SISPRO), the registry of the Ministry of Health and Social Protection, and the High Cost Account (CAC), an organization to trace high expenditure diseases. From both sources age-standardized reported DM prevalence rates per 100.000 inhabitants from 2009 to 2012 were calculated. …”
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Prediction of the Binding to the Nuclear Factor NF-Kappa-B by Constituents from <i>Teucrium polium</i> L. Essential Oil by Renilson Castro de Barros, Renato Araújo da Costa, Nesrine Guenane, Boulanouar Bakchiche, Farouk Benaceur, Omer Elkiran, Suelem Daniella Pinho Farias, Vanessa Regina Silva Mota, Maria Fani Dolabela

“…<i>Teucrium polium</i> L. is a plant with various claims of ethnobotanical use, primarily for inflammatory diseases. Chemical studies have already isolated different types of terpenes from the species, and studies have established its pharmacological potential. …”
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