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33461
Modulation of Adipose-Derived Mesenchymal Stem/Stromal Cell Transcriptome by G-CSF Stimulation
Published 2020-01-01“…Mesenchymal stem/stromal cells (MSCs) exhibit multidifferentiation potential, paralleled with immunomodulatory and trophic properties that make them viable alternative tools for the treatment of degenerative disorders, allograft rejection, autoimmune diseases, and tissue regeneration. MSC functional attributes can be modulated by exposing them to inflammatory-stimulating microenvironments (i.e., priming) before their therapeutic use. …”
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33462
Phenolics from grapefruit peels inhibit HMG-CoA reductase and angiotensin-I converting enzyme and show antioxidative properties in endothelial EA.Hy 926 cells
Published 2015-06-01“…The effects of the phenolic extracts on key enzymes relevant to cardiovascular diseases [3-hydroxy-methyl-3-glutaryl coenzyme A reductase (HMG-CoA reductase) and angiotensin-I converting enzyme (ACE)], cellular antioxidant activity in human endothelial cells (EA.Hy 926) and radicals [1,1-diphenyl-2 picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS)] scavenging abilities were investigated. …”
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33463
Interaction Effects of Lipoprotein Lipase Polymorphisms with Lifestyle on Lipid Levels in a Korean Population: A Cross-sectional Study
Published 2012-06-01“…Lipoprotein lipase (LPL) plays an essential role in the regulation of high-density lipoprotein cholesterol (HDLC) and triglyceride levels, which have been closely associated with cardiovascular diseases. Genetic studies in European have shown that LPL single-nucleotide polymorphisms (SNPs) are strongly associated with lipid levels. …”
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33464
Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa
Published 2024-03-01“…Pregnant women are considered to be a special population group owing to their specific susceptibility to some infectious diseases. Objective. To determine the seroprevalence of anti-SARS-CoV-2 antibodies among pregnant women attending an antenatal clinic. …”
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33465
Replication of the Association of the 6q22.31c Locus near with Pulse Rate in the Korean Population
Published 2012-06-01“…Pulse rate is known to be related to diverse phenotypes, such as cardiovascular diseases, lifespan, arrhythmia, hypertension, lipids, diabetes, and menopause. …”
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33466
Expression of CD24 in Human Bone Marrow-Derived Mesenchymal Stromal Cells Is Regulated by TGFβ3 and Induces a Myofibroblast-Like Genotype
Published 2016-01-01“…The protein CD24 has been reported to be involved in a diverse range of processes such as cancer, adaptive immunity, inflammation, and autoimmune diseases in other cell types. Its expression in hBMSCs, which has not yet been analyzed, may add an important aspect in the understanding of hBMSC biology. …”
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33467
Expression and characterization of exosomal miRNAs in healthy, sub-clinical mastitis and pasteurized milk of buffaloes
Published 2025-01-01“…The miR-148a and miR-186, known to play roles in various diseases like cancer, can withstand commercial pasteurization and boiling, raising the intriguing possibility of transferring through milk exosomes. …”
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33468
The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic Approaches
Published 2024-12-01“…Recent advancements in the fields of epigenetics and senolytics offer promising avenues for understanding and addressing age-related diseases. Epigenetics refers to heritable changes in gene expression without altering the DNA sequence, with mechanisms like DNA methylation, histone modification, and non-coding RNA regulation playing critical roles in aging. …”
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33469
Comparative Analysis of Cardiovascular Development Related Genes in Stem Cells Isolated from Deciduous Pulp and Adipose Tissue
Published 2014-01-01“…Hence, vigorous characterization is needed before introducing any cell for treating targeted diseases.…”
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33470
Reply to the Discussion Started for the Article Titled as “Bitlis Air Pollution Emission Inventory and Estimation of Health Effects by Multiple Linear Regression (Journal of Natura...
Published 2019-07-01“…Number of patients who applied to hospitals due to respiratory and lung diseases obtained from Bitlis Health Provincial Directorate of 2015 were determined. …”
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33471
Lichen Sclerosus Atrophicus with Vitiligo in Pediatrics
Published 2021-03-01“…Age expressed in years, sex, race, genital involvement, evolution time in years, associated symptoms, other associated diseases were taken into account: vitiligo, dermatomyositis, scleroderma, lupus erythematosus, type of lesions, morphea, koebner and treatment. …”
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33472
Serum Endocan Levels Associated with Hypertension and Loss of Renal Function in Pediatric Patients after Two Years from Renal Transplant
Published 2016-01-01“…Endocan is an important biomarker of inflammation and endothelial dysfunction that increases in association with several chronic diseases. Few published data have described the role of endocan in pediatric renal transplant (RT) patients. …”
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33473
Inhibition of Kv1.3 channel restrains macrophage M2 polarization and ameliorates renal fibrosis via regulating STAT6 phosphorylation
Published 2025-03-01“…Collectively, this study suggests that Kv1.3 is essential for macrophage M2 polarization and highlights the potential of Kv1.3 blockers as therapeutic agents for renal fibrosis and other M2 polarization-related diseases.…”
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33474
Effects of time‐restricted feeding and meal timing on an 8‐week fat oxidation exercise training program—A randomized controlled trial
Published 2025-01-01“…Abstract Time‐restricted feeding (TRF) and aerobic exercise are lifestyle interventions to prevent or manage different metabolic diseases. How these interventions interact, including the impact of meal timing, is not well understood. …”
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33475
Oral Administration of Oleuropein and Its Semisynthetic Peracetylated Derivative Prevents Hepatic Steatosis, Hyperinsulinemia, and Weight Gain in Mice Fed with High Fat Cafeteria D...
Published 2015-01-01“…The high consumption of olive tree products in the Mediterranean diet has been associated with a lower incidence of metabolic disorders and cardiovascular diseases. In particular, the protective effects of olive oil have been attributed to the presence of polyphenols such as oleuropein (Ole) and its derivatives. …”
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33476
3D BIOPRINTING IN DENTISTRY: BIBLIOMETRIC ANALYSIS
Published 2024-12-01“… Abstract The World Health Organization (WHO) estimates that oral diseases affect about 3.5 billion people. According to the National Institute of Dental and Craniofacial Research Oral Health Surveillance Report, 2019, nearly 90% of adults between the ages of 20 and 64 had tooth decay, and this percentage did not change significantly between the NHANES 1999-2004 and 2011-2016 cycles. …”
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33477
Investigation of catechin’s anti-inflammatory activity: A bioinformatics and molecular docking study
Published 2024-12-01“… Background: Inflammation plays a key role in the progression of many chronic diseases. As a country with rich biodiversity, Indonesia offers numerous phytochemicals with potential for drug development, including catechin, a natural compound with anti-inflammatory properties. …”
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33478
Label-free proteomic analysis of Duchenne and Becker muscular dystrophy showed decreased sarcomere proteins and increased ubiquitination-related proteins
Published 2025-01-01“…Abstract Muscular dystrophies (MD) are a group of hereditary diseases marked by progressive muscle loss, leading to weakness and degeneration of skeletal muscles. …”
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33479
RNA-seq and In Vitro Experiments Reveal the Protective Effect of Curcumin against 5-Fluorouracil-Induced Intestinal Mucositis via IL-6/STAT3 Signaling Pathway
Published 2021-01-01“…Various studies have evidenced the anticancer role of curcumin in many cancers; except for this effect, studies also indicated a protective role of curcumin in intestinal diseases. Therefore, in this study, we investigated the effect of curcumin on inflammation, intestinal epithelial cell damage in an IM model. 5-FU was used to induce the model of IM in intestinal epithelial cells, and curcumin at different concentrations was administrated. …”
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33480
A Wireless Emergency Telemedicine System for Patients Monitoring and Diagnosis
Published 2014-01-01“…The proposed system can continuously acquire four different physiological signs, for example, ECG, SpO2, temperature, and blood pressure and further relayed them to an intelligent data analysis scheme to diagnose abnormal pulses for exploring potential chronic diseases. The proposed system also has a friendly web-based interface for medical staff to observe immediate pulse signals for remote treatment. …”
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