Targeted Next-Generation Sequencing in Pneumonia: Applications in the Detection of Responsible Pathogens, Antimicrobial Resistance, and Virulence by Liu B, Bao Z, Chen W, Xi X, Ge X, Zhou J, Zheng X, Zhang P, Deng W, Ding R, Zhou M, Fang J

“…Bing Liu,1– 3,* Zhiyao Bao,1– 3,* Wei Chen,1– 3,* Xiaotong Xi,4,5,* Xiao Ge,1– 3 Jun Zhou,1– 3 Xiaoyan Zheng,6 Peipei Zhang,4,5 Wanglong Deng,4,5 Ran Ding,4,5 Min Zhou,1– 3 Jie Fang7 1Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China; 2Institute of Respiratory Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China; 3Shanghai Key Laboratory of Emergency Prevention, Diagnosis and Treatment of Respiratory Infectious Diseases, Shanghai, 200025, People’s Republic of China; 4State Key Laboratory of Neurology and Oncology Drug Development, Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd., Nanjing, 210018, People’s Republic of China; 5Nanjing Simcere Medical Laboratory Science Co., Ltd., Nanjing, 210018, People’s Republic of China; 6Department of Pulmonary and Critical Care Medicine, Zhoushan Branch of Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Zhoushan, 316000, People’s Republic of China; 7Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Fang, Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin 2nd Road, Shanghai, 200025, People’s Republic of China, Email fj40517@rjh.com.cn Min Zhou, Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin 2nd Road, Shanghai, 200025, People’s Republic of China, Email doctor_zhou_99@163.comBackground: Targeted next-generation sequencing (tNGS) is a high-throughput and cost-effective diagnostic alternative for pneumonia, with the ability to simultaneously detect pathogens, antimicrobial resistance genes, and virulence genes. …”
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Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPARγ and Identification of TUSC5 Coding Variants in Lean and Obese Humans by Trina A. Knotts, Hyun Woo Lee, Jae Bum Kim, Pieter J. Oort, Ruth McPherson, Robert Dent, Keisuke Tachibana, Takefumi Doi, Songtao Yu, Janardan K. Reddy, Kenji Uno, Hideki Katagiri, Magdalena Pasarica, Steven R. Smith, Dorothy D. Sears, Michel Grino, Sean H. Adams

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The Adaptation, Implementation, and Performance Evaluation of Intake24, a Digital 24-h Dietary Recall Tool for South Asian Populations: The South Asia Biobank by Divya Bhagtani, Birdem Amoutzopoulos, Toni Steer, David Collins, Suzanna Abraham, Bridget A Holmes, Baldeesh K Rai, Rajendra Pradeepa, Sara Mahmood, Abu Ahmed Shamim, Poorvee Mathur, Lathika Athauda, Laksara De Silva, Khadija I Khawaja, Vinitaa Jha, Anuradhani Kasturiratne, Prasad Katulanda, Malay K Mridha, Ranjit M Anjana, John C Chambers, Polly Page, Nita G Forouhi

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Safety and efficacy of telaprevir in treatment of a chronic hepatitis C in patients of the Russian population included in early access program study by D. T. Abrurakhmanov, V. G. Morozov, I. G. Nikitin, P. O. Bogomolov, N. I. Geyvandova, Ye. N. Bessonova, I. G. Bakulin, V. A. Isakov, K. V. Zhdanov, M. V. Mayevskaya, Ye. A. Nurmukhametova, E. Z. Burnevich, Ye. V. Chesnokov, V. D. Pasechnikov, A. Hill, I. Lonjon-Domanec, S. N. Kizhlo

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Immunomodulatory and growth-promoting effects of Rauwolfia serpentina root powder in broiler chicks challenged with Salmonella Gallinarum by Yingyu Zhang, Hiba Rehman, Farina Khattak, Maryam Tariq, Bushra Nisar Khan, Sadia Chaman, Ayaesha Riaz, Muhammad Ovais Omer, Aqib Ali, Qamar un Nisa, Muhammad Muddassir Ali, Gulbeena Saleem

“…BackgroundAmid growing concern about antimicrobial resistance due to the irrational use of antibiotics in treating common poultry diseases, particularly Salmonella which is a foodborne pathogen in humans. …”
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Safety and effects of anti-obesity medications on weight loss, cardiometabolic, and psychological outcomes in people living with overweight or obesity: a systematic review and meta... by Leiling Liu, Zhiqi Li, Wenrui Ye, Pu Peng, Yurong Wang, Luqing Wan, Jiangnan Li, Mei Zhang, Yihua Wang, Runqi Liu, Danyan Xu, Jingjing Zhang

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Research progress of rehabilitation nursing for stroke patients (脑卒中康复护理研究进展) by WANG Li (王丽)

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Phages as potential life-saving therapeutic option in the treatment of multidrug-resistant urinary tract infections by Beata Zalewska-Piątek, Michalina Nagórka

“…Phage therapy (PT) has emerged as a promising alternative due to its specificity, safety and efficacy against multidrug-resistant (MDR) pathogens causing infectious diseases. PT demonstrates significant potential in treating chronic and recurrent UTIs, also including catheter-associated infection by reducing bacterial biofilms, delaying catheter blockage, and enhancing antibiotic efficacy when used in combination. …”
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Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature by Amna Ahmed, Alejandro Granillo, Ethan Burns, Kerri Glassner, Nishath Naseem, Christopher Force, Suzanne M. Crumley, Ashley Drews

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Mucocutaneous Manifestations of HIV and the Correlation with WHO Clinical Staging in a Tertiary Hospital in Nigeria by Olumayowa Abimbola Oninla

“…Skin diseases are indicators of HIV/AIDS which correlates with WHO clinical stages. …”
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Comparative safety profile of tyrosine kinase inhibitors in NSCLC: a network meta-analysis of hypertension and thrombotic risks by Mingming Tan, Chenwei Pu, Zhenzhen Wang, Chengwei Jin

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Sex of Household Heads and Attitude Towards Home Gardening in Southwest, Nigeria by Abdulrazaq Kamal DAUDU, Sidiqat Adeyemi Aderinoye-Abdulwahab

“…Major constraints reported by households in home garden production include damage from pests, diseases, animals, and theft (male: 1.98±0.63; female: 1.96±0.61) and limited access to agricultural inputs such as seeds, tools, and capital (male: (1.94±0.77; female: 2.00±0.75). …”
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Disturbance of Inorganic Phosphate Metabolism in Diabetes Mellitus: Its Relevance to the Pathogenesis of Diabetic Retinopathy by H. Vorum, J. Ditzel

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Fish Health Management Considerations in Recirculating Aquaculture Systems - Part 1: Introduction and General Principles by Roy Yanong

“…They certainly are not a “silver-bullet” for eliminating fish diseases. In addition, defining the primary intended use of a system will help optimize efficiency and utility in the design process. …”
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Editorial: The expanding Frontiers of stem cells therapy in oral maxillo-facial engineering and regenerative medicine by Christiane L. Salgado, Christiane L. Salgado, Andrea Cochis, Elena M. Varoni, Rui Amaral Mendes, Rui Amaral Mendes, Rui Amaral Mendes, Rui Amaral Mendes

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COVID-19 pandemic and its psychological impact among healthy Portuguese and Spanish nursing students by Carlos Laranjeira, Ana Querido, Goreti Marques, Mafalda Silva, Daniela Simões, Luísa Gonçalves, Rita Figueiredo

“…The results provide evidence that infectious diseases, such as COVID-19, may significantly influence mental health. …”
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The phenomenon of procrastination by T. N. Kochetkova

“…It is energy-consuming, can lead to ideas destruction about one’s own personality and chronic diseases. Negative emotional background, weak self-control and low self-regulation are all prerequisites for developing procrastination and dependence on digital reality. …”
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Evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistance by Shalini Kumari, Imsensenba Longkumer, Mamta Sharma, Shashank Tripathi

“…Aim: It was thought that resistance acquired during treatment of systemic diseases can lead to resistant bacteria in eye infections. …”
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Selective list of VIR’s methodological recommendations (guidelines) for 2000–2022 by Article Editorial

“…All recommendations (guidelines) are an assemblage of documents dedicated to the study, conservation, and replenishment of the unique global plant genetic resources collection held by VIR; plant breeding; seed production; cultivation; resistance of individual crops to diseases and pests; herbarization; long-term seed storage; biochemical, mycological, phytopathological, genetic, and biotechnological research methods; and many other issues. …”
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Thrombomodulin: A Bifunctional Modulator of Inflammation and Coagulation in Sepsis by Takayuki Okamoto, Hironobu Tanigami, Koji Suzuki, Motomu Shimaoka

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