Notoginsenoside Fc Accelerates Reendothelialization following Vascular Injury in Diabetic Rats by Promoting Endothelial Cell Autophagy by Jingjing Liu, Chunyu Jiang, Xu Ma, Lishuai Feng, Jianbo Wang

“…In summary, this study supported the notion that Fc could accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy, suggesting that Fc may exert therapeutic benefits for early endothelial injury and restenosis following intervention in diabetes-associated vascular diseases.…”
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Acute stimulation of PBMCs drives switch from dopamine-induced anti- to proinflammatory phenotype of monocytes only in women by Leonie Fleige, Silvia Capellino

“…Another contributing factor appears to be sex, as sex-specific differences in the dopaminergic pathway are described in the neurological context as well as in autoimmune diseases. However, a deeper understanding of these differences in peripheral immune cells remains limited. …”
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Gingival Mesenchymal Stem/Progenitor Cells: A Unique Tissue Engineering Gem by Karim M. Fawzy El-Sayed, Christof E. Dörfer

“…The review further demonstrates their immunomodulatory properties, the transplantation preconditioning attempts via multiple biomolecules to enhance their attributes, and the experimental therapeutic applications conducted to treat multiple diseases in experimental animal models in vivo. G-MSCs show remarkable tissue reparative/regenerative potential, noteworthy immunomodulatory properties, and primary experimental therapeutic applications of G-MSCs are very promising, pointing at future biologically based therapeutic techniques, being potentially superior to conventional clinical treatment modalities.…”
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Isolation, identification, and characterisation of the malachite green detoxifying bacterial strain Bacillus pacificus ROC1 and the azoreductase AzrC by Shanza Bibi, Callum W. Breeze, Vusqa Jadoon, Anum Fareed, Alina Syed, Rebecca L. Frkic, Habiba Zaffar, Muhammad Ali, Iftikhar Zeb, Colin J. Jackson, Tatheer Alam Naqvi

“…Abstract Malachite green (MG) is used as a dye for materials such as wood, cotton, and nylon, and is used in aquaculture to prevent fungal and protozoan diseases. However, it is highly toxic, with carcinogenic, mutagenic, and teratogenic properties, resulting in bans worldwide. …”
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Cultured Human Airway Epithelial Cells (Calu-3): A Model of Human Respiratory Function, Structure, and Inflammatory Responses by Yan Zhu, Aaron Chidekel, Thomas H. Shaffer

“…The Calu-3 cell preparation is a sensitive and efficient preclinical model to study human respiratory processes and diseases related to oxygen- and ventilator-induced lung injury.…”
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A Cyanotic Newborn with a Pink Right Upper Extremity by Matthias Beichl, Andreas Hanslik, Daniel Zimpfer, Judith Rittenschober-Boehm, Katrin Nagl, Ina Michel-Behnke

“…Aberrant origin of the subclavian artery (SCA) is a well-known vascular anomaly as part of congenital heart diseases with the left subclavian artery (LSCA) being more frequently affected than the right subclavian artery (RSCA). …”
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Synthesis and Experimental Validation of New PDI Inhibitors with Antiproliferative Activity by Mariateresa Badolato, Gabriele Carullo, Francesca Aiello, Antonio Garofalo

“…The inhibition of PDI’s activity may have a therapeutic role, in various diseases, including cancer. In the present study, we designed and synthesized a diversified small library of compounds with the aim of identifying a new class of PDI inhibitors. …”
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A pathogenic COL7A1 variant highlights semi-dominant inheritance in dystrophic epidermolysis bullosa by Saira Sattar, Thashi Bharadwaj, Umm-e- Kalsoom, Anushree Acharya, Saadullah Khan, Suzanne M. Leal, Isabelle Schrauwen

“…This study highlights the importance of considering semi-dominant inheritance models for dystrophic epidermolysis bullosa and other Mendelian diseases with an autosomal recessive mode of inheritance, as it can significantly impact diagnosis and genetic counseling.…”
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Scratch Scoring by a Sheet-shaped Body Vibrometer in Nocturnal Sleep: A Pilot Study Compared with Infrared Video Recording by Saori Toyota, Takamasa Kogure, Eitaro Kondo, Ken-ichi Yasuda, Yozo Ishiuji, Toshiya Ebata

“…Itching tends to worsen at night in patients with itchy skin diseases, such as atopic dermatitis. Unconscious scratching during sleep can exacerbate symptoms, cause sleep disturbances, or reduce quality of life. …”
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The Role of Adrenomedullin in the Renal NADPH Oxidase and (Pro)renin in Diabetic Mice by Michio Hayashi, Akihiro Tojo, Tatsuo Shimosawa, Toshiro Fujita

“…Adrenomedullin has an antioxidative action and protects organs in various diseases. To clarify the role of adrenomedullin in diabetic nephropathy, we investigated the NADPH oxidase expression, renin-secreting granular cell (GC) hyperplasia, and glomerular matrix expansion in the streptozotocin (STZ)-induced diabetic adrenomedullin gene knockout (AMKO) mice compared with the STZ-diabetic wild mice at 10 weeks. …”
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Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids by Martin Roumain, Giulio G. Muccioli

“…For this reason, they are increasingly studied together for their implications in various diseases. However, due to analytical challenges inherent to the nature of these analytes, very few methods have been developed for the simultaneous analysis of these lipids. …”
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Genus <i>Nicotiana</i> L.: a review of traits significant for ornamental crop production by E. G. Baranova, K. I. Ivanitsky, V. I. Suchkov

“…The collection of Nicotiana L. species (Solanaceae) maintained at the All-Russian Scientific Research Institute of Tobacco, Makhorka and Tobacco Products (VNIITTI) is a valuable genetic resource used in breeding and genetic research on interspecific hybridization, cytoplasmic male sterility, and as a genebank for resistance to major tobacco diseases. Many species have ornamental features and properties: bright color and unusual morphology of the corolla, aroma, peculiar plant shape and others, and are promising for use in landscaping and garden designing. …”
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Utilization of preventative health checkup services in China among middle-aged and older adult population: evidence from China’s 28 provinces by Jingyu Shen, Jingyu Shen, Weiji Fang, Weiji Fang, Yating Zhu, Yating Zhu, Chunli Ye, Chunli Ye, Yanhua Zhu, Yanhua Zhu, Yanling Tao, Yanling Tao

“…Utilization was significantly influenced by age, area of residence, education level, social insurance, health insurance, personal income, presence of chronic diseases, and life satisfaction. Older adults, urban residents, and individuals with higher income or chronic conditions were more likely to utilize health checkup services.ConclusionThere are significant urban–rural disparities in the utilization of health checkup services among middle-aged and older adult people in China. …”
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Predicting drug combination side effects based on a metapath-based heterogeneous graph neural network by Leixia Tian, Qi Wang, Zhiheng Zhou, Xiya Liu, Ming Zhang, Guiying Yan

“…Generally, synergistic drug combinations are crucial in treatment for many diseases. However, the toxic side effects of drug combinations are probably increased with the increase of drugs numbers, so the accurate prediction of toxic side effects of drug combinations is equally important. …”
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Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function by Gustavo Della-Flora Nunes, Lindsay A. Osso, Johana A. Haynes, Lauren Conant, Michael A. Thornton, Michael E. Stockton, Katherine A. Brassell, Amanda Morris, Yessenia I. Mancha Corchado, John A. Gaynes, Anthony R. Chavez, Michaelanne B. Woerner, Deidre A. MacKenna, Aryan Alavi, Anne Danks, Alon Poleg-Polsky, Rohan Gandhi, Jeffrey A. Vivian, Daniel J. Denman, Ethan G. Hughes

“…Abstract Myelin loss induces neural dysfunction and contributes to the pathophysiology of neurodegenerative diseases, injury conditions, and aging. Because remyelination is often incomplete, better understanding endogenous remyelination and developing remyelination therapies that restore neural function are clinical imperatives. …”
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The hematinic effect of some medicinal plants used traditionally for the treatment of anemia: A narrative review by Huda Ahmed Abuaraki, Samia Mohamed Ali Elbadawi, Hatim Ali Elsheikh, Ayman Ragab Baiuomy

“…A high percentage of the world’s population uses medicinal plants to treat diseases, and in African countries, this rate is much higher. …”
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Oral Verruciform Xanthoma within Lichen Planus: A Case Report and Literature Review by Vasileios I. Theofilou, Alexandra Sklavounou, Prokopios P. Argyris, Evanthia Chrysomali

“…The occurrence of the lesion in patients with immune-mediated mucocutaneous diseases may suggest a role of localized epithelial cell damage and chronic inflammation in its pathogenesis. …”
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Photoredox-Catalyzed Decomposition of Nitric Oxide over Au-Enhanced Surface Plasmon Resonance ZnSn(OH)6 Microcubes by Minh-Thuan Pham, Truc Mai Thi Nguyen, Sheng-Jie You, Ya-Fen Wang

“…Therein, nitric oxide (NO) is the leading cause of the greenhouse effect, acid rain, and respiratory diseases. Therefore, discovering a low-cost, environmentally friendly, highly efficient photocatalysis technique to remove NO is necessary and urgent. …”
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Shionone Relieves Urinary Tract Infections by Removing Bacteria from Bladder Epithelial Cells by Hao Yin, Jiaoli Zhu, Yi Jiang, Yijing Mao, Chenquan Tang, Hui Cao, Yufang Huang, Huijun Zhu, Jianping Luo, Qingjiang Jin, Qinglei Jin, Yi Xue, Xin Wang

“…In clinical practice, urinary tract infections (UTIs) are second only to respiratory infections in terms of infectious diseases. In recent years, drug resistance of Escherichia coli (E. coli) has increased significantly. …”
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Transcriptome Analysis of Long Noncoding RNAs in Toll-Like Receptor 3-Activated Mesenchymal Stem Cells by Shihua Wang, Xiaoxia Li, Robert Chunhua Zhao

“…Mesenchymal stem cells (MSCs) possess great immunomodulatory capacity which lays the foundation for their therapeutic effects in a variety of diseases. Recently, toll-like receptors (TLR) have been shown to modulate MSC functions; however, the underlying molecular mechanisms are poorly understood. …”
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