Contribution of Statins towards Periodontal Treatment: A Review by Catherine Petit, Fareeha Batool, Isaac Maximiliano Bugueno, Pascale Schwinté, Nadia Benkirane-Jessel, Olivier Huck

“…The pleiotropic effects of statins have been evaluated to assess their potential benefit in the treatment of various inflammatory and immune-mediated diseases including periodontitis. Herein, the adjunctive use of statins in periodontal therapy in vitro, in vivo, and in clinical trials was reviewed. …”
Get full text

Predicting Metabolic Syndrome Using the Random Forest Method by Apilak Worachartcheewan, Watshara Shoombuatong, Phannee Pidetcha, Wuttichai Nopnithipat, Virapong Prachayasittikul, Chanin Nantasenamat

“…Therefore, using RF to predict MS may be potentially beneficial in identifying MS status for preventing the development of diabetes mellitus and cardiovascular diseases.…”
Get full text

Cost-effective whole-cell biosynthesis of ursodeoxycholic acid using engineered Escherichia coli with a multienzyme cascade by Xue Zhang, Xue Zhang, Jiagang Xin, Mengyu Liu, Mengyu Liu, Yue Zhang, Yue Zhang, Haoni Luan, Haoni Luan, Wei Feng, Wei Feng, Fei Wang, Fei Wang, Wei Xu, Wei Xu, Peng Song, Peng Song

“…Ursodeoxycholic acid (UDCA) can be used as a drug to treat various liver and bile diseases. Currently, the biological synthesis of UDCA is predominantly conducted via a two-step enzymatic process in which synthesis is catalyzed by 7α-hydroxysteroid dehydrogenase (7α-HSDH) and 7β-hydroxysteroid dehydrogenase (7β-HSDH) in succession, utilizing chenodeoxycholic acid (CDCA) as the substrate. …”
Get full text

Non-enzymatic protein targeting agents as a promising strategy for cancer treatment by Madison Ambrose, Jeremy Lee, Aleem Syed, Zamal Ahmed, Guang Peng

“…The combination of the highly selective PROTACs and exploitation of cellular protein degradation pathways provides the opportunity to treat diseases that were previously deemed incurable due to lack of enzymatic activities of the targeted proteins. …”
Get full text

Quality of Life Theory III. Maslow Revisited by Soren Ventegodt, Joav Merrick, Niels Jorgen Andersen

“…It seems that Maslow�s concept of self-actualization can play an important role in modern medicine. As most chronic diseases often do not disappear in spite of the best biomedical treatments, it might be that the real change our patients have for betterment is understanding and living the noble path of personal development. …”
Get full text

Robustness of Dengue Complex Network under Targeted versus Random Attack by Hafiz Abid Mahmood Malik, Faiza Abid, Mohamed Ridza Wahiddin, Zeeshan Bhatti

“…Dengue virus infection is one of those epidemic diseases that require much consideration in order to save the humankind from its unsafe impacts. …”
Get full text

A Case of TAFRO Syndrome Developed after COVID-19 Vaccination by Hitomi Hirose, Hitoshi Suzuki, Yukako Umezawa, Masako Iwasaki, Hiromitsu Fukuda, Hisatsugu Takahara, Shigeki Tomita, Yusuke Suzuki

“…Several complications, such as renal, hematological, and heart diseases, have been reported; however, its pathogenesis is unclear. …”
Get full text

in vitro evaluation of the efficiency of Artemisia judaica leaf extract on sporulation of Eimeria papillate oocysts and its cytotoxicity by M.A. Esam, N.M. Saleh, A.G. Rewaida, A.Q.H. Waleed, A. Afaf, A.A. Sarah, Al-Q. Saleh

“…The treatment of a wide variety of parasite diseases can be done with natural products that don't harm the environment. …”
Get full text

First Report on the Emergence of <i>Neopestalotiopsis rosae</i> as a Severe Economic Threat to Strawberry Production in Germany by Tom E. Schierling, Ralf T. Voegele, Abbas El-Hasan

“…However, their yield is often adversely affected by fungal diseases. This study describes <i>Neopestalotiopsis rosae</i> as a newly emerging pathogen responsible for leaf blight and fruit rot in strawberries in Germany. …”
Get full text

Central Sensitization-Based Classification for Temporomandibular Disorders: A Pathogenetic Hypothesis by Annalisa Monaco, Ruggero Cattaneo, Maria Chiara Marci, Davide Pietropaoli, Eleonora Ortu

“…Clinical examination and CSI cannot identify the central site(s) affected in these diseases. Ultralow frequency transcutaneous electrical nerve stimulation (ULFTENS) is extensively used in TMD and in dental clinical practice, because of its effects on descending pain modulation pathways. …”
Get full text

Effect of Naphthalene Acetic Acid on the Adventitious Rooting in Shoot Cuttings of Andrographis paniculata (Burm.f.) Wall. ex Nees: An Important Therapeutical Herb by Md. Sanower Hossain, Zannat Urbi

“…Andrographis paniculata is one of the most important therapeutical herbs, widely used in traditional medical systems for the treatment of diverse diseases for thousands of years. This study was carried out to assess the effect of 1-naphthaleneacetic acid (NAA) on adventitious rooting in A. paniculata shoot cuttings. …”
Get full text

The Impact of Adequate Selenium Intake on Severity Symptoms and Quality of Life among People with Allergic Rhinitis by Thanyapron Tiyawisutsri, Napassorn Suwanpanyakul, Weeraya Kongkasri, Kamonwan Thongsri, Roger Timothy Callaghan, Alongkote Singhato

“…Allergic Rhinitis (AR) is one of the most common immune-related diseases that affects the quality of life among patients. …”
Get full text

Nasal food challenge with hen's egg white allergen by Edyta Krzych-Fałta, Andrzej Namysłowski, Sławomir Białek, Monika E. Czerwińska, Konrad Furmańczyk, Aleksandra Tylewicz, Adam Sybilski, Bolesław Samoliński, Oksana Wojas

“…Abstract Background Nasal allergen provocation tests are an important part of the diagnostics of allergic diseases triggered by environmental factors. Recently, increased attention has been paid to the potential use of this method in the diagnosis of food allergy. …”
Get full text

The impact of atopy on the clinical characteristics of mycoplasma pneumoniae pneumonia in pediatric patients by Yujie Qin, Yuxia Yang, Junxiang Li, Jun Guan

“…Abstract Mycoplasma pneumoniae (MP) is one of the pathogens that cause community-acquired pneumonia in children. Atopic diseases are also common in children. However, the impact of atopy on Mycoplasma pneumoniae pneumonia (MPP) in children is still unclear. …”
Get full text

Anti-Inflammatory Strategy for M2 Microglial Polarization Using Retinoic Acid-Loaded Nanoparticles by Marta Machado-Pereira, Tiago Santos, Lino Ferreira, Liliana Bernardino, Raquel Ferreira

“…Altogether, our data indicate that RA-NP may be envisioned as a promising therapeutic agent for brain inflammatory diseases.…”
Get full text

The Acetone Extract of Sclerocarya birrea (Anacardiaceae) Possesses Antiproliferative and Apoptotic Potential against Human Breast Cancer Cell Lines (MCF-7) by Nicoline Fri Tanih, Roland Ndip Ndip

“…Interesting antimicrobial data from the stem bark of Sclerocarya birrea, which support its use in traditional medicine for the treatment of many diseases, have been delineated. The current study was aimed to further study some pharmacological and toxicological properties of the plant to scientifically justify its use. …”
Get full text

Role of Cathepsin S in Periodontal Inflammation and Infection by S. Memmert, A. Damanaki, A. V. B. Nogueira, S. Eick, M. Nokhbehsaim, A. K. Papadopoulou, A. Till, B. Rath, S. Jepsen, W. Götz, C. Piperi, E. K. Basdra, J. A. Cirelli, A. Jäger, J. Deschner

“…The objective of this study was to investigate whether cathepsin S is involved in the pathogenesis of periodontal diseases. Human periodontal fibroblasts were cultured under inflammatory and infectious conditions elicited by interleukin-1β and Fusobacterium nucleatum, respectively. …”
Get full text

Microtissues in Cardiovascular Medicine: Regenerative Potential Based on a 3D Microenvironment by Julia Günter, Petra Wolint, Annina Bopp, Julia Steiger, Elena Cambria, Simon P. Hoerstrup, Maximilian Y. Emmert

“…More people die annually from cardiovascular diseases than from any other cause. In particular, patients who suffer from myocardial infarction may be affected by ongoing adverse remodeling processes of the heart that may ultimately lead to heart failure. …”
Get full text

Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues by Ioannis Alexandros Charitos, Andrea Ballini, Stefania Cantore, Mariarosaria Boccellino, Marina Di Domenico, Elisa Borsani, Riccardo Nocini, Michele Di Cosola, Luigi Santacroce, Lucrezia Bottalico

“…Stem cells can be used to replace damaged cells or regenerate organs and have broadened our knowledge of the development and progression of certain diseases. Despite significant advances in understanding stem cell biology, several problems limit their use. …”
Get full text

Occupational Hazards Knowledge among a Sample of Medical and Paramedical Staff in Baghdad City by Sajjad M. hasan, Suhair M. Hassoun, Luma H. Ali

“… Occupational hazards include any behaviors which possess the potential to cause or raise risks at the workplace, as well as the compounding effects of accidents and occupational diseases within workers in the health and medical field. …”
Get full text