Effectiveness of Palivizumab in Preventing RSV Hospitalization in High Risk Children: A Real-World Perspective by Nusrat Homaira, William Rawlinson, Thomas L. Snelling, Adam Jaffe

“…This review supports the recommended use of palivizumab for reducing RSV-associated hospitalization rates in premature infants born at gestational age < 33 weeks and in children with chronic lung and heart diseases. Data are limited to allow commenting on the protective effect of palivizumab among other high risk children, including those with Down syndrome, cystic fibrosis, and haematological malignancy, indicating further research is warranted in these groups.…”
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Inactivation of Zika Virus with Hydroxypropyl-Beta-Cyclodextrin by Cory R. Hewitt, Nicholas J. Wixon, Arthur Gallegos, You Zhou, Victor C. Huber, M. Scott Killian

“…<b>Background/Objectives</b>: Zika virus (ZIKV) infection is associated with life-threatening diseases in humans. To date, there are no available FDA-approved therapies or vaccines for the specific treatment or prevention of ZIKV infection. …”
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An Overview: PAH and Nitro-PAH Emission from the Stationary Sources and their Transformations in the Atmosphere by Yen-Yi Lee, Yen-Kung Hsieh, Bo-Wun Huang, Justus Kavita Mutuku, Guo-Ping Chang-Chien, Shiwei Huang

“…They are mutagenic, persistent in the environment, and cause diseases and mortality worldwide. Nitro-PAHs have a higher carcinogenic potential than their parent PAHs; however, the scientific community’s understanding of their properties and quantities in different matrices is still rudimentary. …”
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Database Analysis of Eplerenone Use in Japanese Hypertensive Patients in Clinical Practice by Shoko Takahashi, Yoichi Ii, Yuji Yamamoto, Aya Ikeda, Yoko Fujimoto

“…Thus, this study was aimed at examining the characteristics of eplerenone-prescribed hypertensive patients in Japan, describing the combination patterns of antihypertensive medications, and comparing eplerenone’s mean doses with respect to concomitant diseases. Data of 160,992 hypertensive patients who used the same drugs for six months or more were collected from an insurance database from January 1, 2009, to December 31, 2013. …”
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A Cellular Potts model simulating cell migration on and in matrix environments by Marco Scianna, Luigi Preziosi, Katarina Wolf

“…In conclusion, we here propose amathematical modeling approach that serves to characterize cellmigration as a biological phenomenon in healthy and diseased tissuesand in engineering applications.…”
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Nanomédicaments pour le traitement de maladies graves et recherches duales by Couvreur, Patrick

“…Nanomedicines have made significant advances in various therapeutic areas such as oncology, infectious diseases, and several neurological disorders. They have also contributed to groundbreaking discoveries, including the introduction of the first mRNA vaccine (against COVID-19), and have improved certain imaging and diagnostic techniques, too. …”
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Decoding NAD+ Metabolism in COVID-19: Implications for Immune Modulation and Therapy by Shixu Song, Jialing Gan, Qiuyue Long, Zhancheng Gao, Yali Zheng

“…This will be essential for developing targeted NAD+ therapies, potentially transforming the management of COVID-19 and setting a precedent for addressing other infectious diseases.…”
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Application of Metabolomics to Study Effects of Bariatric Surgery by Paulina Samczuk, Michal Ciborowski, Adam Kretowski

“…New findings can suggest new directions of surgery technics modifications, contribute to broadening knowledge about obesity and diseases related to it, and perhaps develop nonsurgical methods of treatment in the future.…”
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Upregulated Expression of Indoleamine 2, 3-Dioxygenase in Primary Breast Cancer Correlates with Increase of Infiltrated Regulatory T Cells In Situ and Lymph Node Metastasis by Jinpu Yu, Jingyan Sun, Shizhen Emily Wang, Hui Li, Shui Cao, Yizi Cong, Juntian Liu, Xiubao Ren

“…The IDO expression in cancer was higher than that in benign diseases both at RNA and protein levels. The IDO expression was significantly upregulated in tumors of more advanced stages and with more extensive lymph node metastasis, and displayed positive linear correlation with the density of Foxp3+ Tregs. …”
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Influence of Epinastine Hydrochloride, an H1-Receptor Antagonist, on the Function of Mite Allergen-Pulsed Murine Bone Marrow-Derived Dendritic Cells In Vitro and In Vivo by Ken-Zaburo Oshima, Kazuhito Asano, Ken-Ichi Kanai, Miyuki Suzuki, Harumi Suzaki

“…These results indicate that EP inhibits the development of Th2 immune responses through the modulation of DC functions and results in favorable modification of clinical status of allergic diseases.…”
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Salmon Muscle Adherence to Polymer Coatings and Determination of Antibiotic Residues by Reversed-Phase High-Performance Liquid Chromatography Coupled to Selected Reaction Monitorin... by E. Zumelzu, M. J. Wehrhahn, O. Muñoz, F. Rull

“…New aquaculture production systems employ antibiotics such as florfenicol, florfenicol amine, oxytetracycline, and erythromycin to control diseases. The introduction of antibiotics is a matter of concern regarding the effects on human health and biodiversity. …”
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Regional Aggressive Root Resorption Caused by Neuronal Virus Infection by Inger Kjær, Carsten Strøm, Nils Worsaae

“…Anamnestic information revealed severe virus diseases during childhood, meningitis in one case and whooping cough in the other. …”
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Impact of surgery on visual acuity and life quality of senile patients by Mariela Julia Curbelo Gómez, Maria Adela Llull Tombo

“…<br /><strong>Objective:</strong> To assess the visual outcome, life quality and advantages of microsurgery in one of the most common visual diseases. <strong><br />Methods:</strong> A prospective, descriptive, study including variables as age, gender, general and visual personal pathological history of all the patients who attended to the provisional consultation of the General Hospital “Dr. …”
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Illumination on Chemical Compounds from Qufeng Zhitong Capsule and Its Potential Pharmacological Mechanism against Rheumatoid Arthritis Based on UHPLC/Q-Orbitrap-MS Combined with N... by Mengjie Xue, Lihua Zhang, Yuting Zhao, Qixuan Mu, Ying Cui, Ke Qian, Xin Chai

“…Qufeng Zhitong capsule (QZC), a Chinese patent medicine officially approved in China for the treatment of rheumatoid arthritis (RA) and other diseases, possesses the primary effects of dispelling wind, relieving pain, and promoting blood circulation, whose clinical applications have been confined owing to the incomplete elucidation of its chemical compositions and the underlying molecular mechanism for the treatment of RA. …”
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ISMAC: An Intelligent System for Customized Clinical Case Management and Analysis by Mingyu You, Chong Chen, Guo-Zheng Li, Shi-Xing Yan, Sheng Sun, Xue-Qiang Zeng, Qing-Ce Zhao, Liao-Yu Xu, Su-Ying Huang

“…Customized templates with standard and expert-standard symptoms, diseases, syndromes, and Chinese Medince Formula (CMF) are constructed in ISMAC, according to the clinical diagnosis and treatment characteristic of each TCM specialist. …”
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The Interaction of lncRNA-HEIH and lncRNA-HULC with HBXIP in Hepatitis B Patients by Lingjuan Ruan, Lifei Huang, Lilai Zhao, Qiang Wang, Xiaocheng Pan, Anmin Zhang, Qiuping Bai, Zongjun Lv

“…These results suggest that lncRNA-HEIH and lncRNA-HULC interact with HBXIP in hepatitis B-related diseases.…”
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Bacterial extracellular vesicles in the initiation, progression and treatment of atherosclerosis by Yuling Lin, Jingyu Wang, Fan Bu, Ruyi Zhang, Junhui Wang, Yubing Wang, Mei Huang, Yiyi Huang, Lei Zheng, Qian Wang, Xiumei Hu

“…Atherosclerosis is the primary cause of cardiovascular and cerebrovascular diseases. However, current anti-atherosclerosis drugs have shown conflicting therapeutic outcomes, thereby spurring the search for novel and effective treatments. …”
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Detecting Atrial Fibrillation Using Smartwatches by Agnieszka Kulczycka-Rowicka, Julianna Podolec, Silvia Ciraolo, Joanna Wojda, Adam Sobiński, Zuzanna Kościuszko, Katarzyna Kurza, Matylda Czerwonka, Katarzyna Lesiczka-Fedoryj, Anna Walczak

“…Smartwatches are a promising tool supporting the diagnosis of cardiac arrhythmias and monitoring already diagnosed diseases. Further research and continuous improvement of technologies are needed so that it is possible to use them in everyday medical practice. …”
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Chemical Feature-Based Molecular Modeling of Urotensin-II Receptor Antagonists: Generation of Predictive Pharmacophore Model for Early Drug Discovery by Anubhuti Pandey, Sarvesh Kumar Paliwal, Shailendra Kumar Paliwal

“…Moreover, the pharmacophore model has been used as a 3D query for virtual screening which served to detect prospective new lead compounds which can be further optimized as UT antagonists with potential for treatment of cardiovascular diseases.…”
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Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine by Kerry Rennie, Andrée Gruslin, Markus Hengstschläger, Duanqing Pei, Jinglei Cai, Toshio Nikaido, Mahmud Bani-Yaghoub

“…While a major focus of research has been the use of amniotic membrane and fluid in tissue engineering and cell replacement, AM- and AF-derived cells may also have capabilities in protecting and stimulating the repair of injured tissues via paracrine actions, and acting as vectors for biodelivery of exogenous factors to treat injury and diseases. Much progress has been made since the discovery of AM and AF cells with stem cell characteristics nearly a decade ago, but there remain a number of problematic issues stemming from the inherent heterogeneity of these cells as well as inconsistencies in isolation and culturing methods which must be addressed to advance the field towards the development of cell-based therapies. …”
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