α-amanitin induces hepatotoxicity via PPAR-γ inhibition and NLRP3 inflammasome activation by Haowei Wang, Huijie Zhang, Lin Miao, Chan Wang, Hanxin Teng, Xiaodong Li, Xiaoxing Zhang, Genmeng Yang, Shangwen Wang, Xiaofeng Zeng

“…The study highlights the interplay between α-amanitin, NLRP3, and PPAR-γ in hepatotoxicity, proposing potential therapeutic targets for mushroom poisoning-induced liver diseases.…”
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β-Glucan-modified nanoparticles with different particle sizes exhibit different lymphatic targeting efficiencies and adjuvant effects by Wen Guo, Xinyue Zhang, Long Wan, Zhiqi Wang, Meiqi Han, Ziwei Yan, Jia Li, Ruizhu Deng, Shenglong Li, Yuling Mao, Siling Wang

“…The results also indicate that β-glucan-modified MSN, with a particle size of ∼100 nm, has a great potential as a vaccine delivery vehicle and immune adjuvant and offers a novel approach for the delivery of multiple therapeutic agents that target other lymph-mediated diseases.…”
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3D bioprinting for the production of a perfusable vascularized model of a cancer niche by Federico Maggiotto, Federico Maggiotto, Lorenzo Bova, Lorenzo Bova, Lorenzo Bova, Sara Micheli, Sara Micheli, Camilla Pozzer, Pina Fusco, Pina Fusco, Paolo Sgarbossa, Fabrizio Billi, Elisa Cimetta, Elisa Cimetta

“…The ever-growing need for improved in vitro models of human tissues to study both healthy and diseased states is advancing the use of techniques such as 3D Bioprinting. …”
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Neuron-Glia Interactions in Neural Plasticity: Contributions of Neural Extracellular Matrix and Perineuronal Nets by Egor Dzyubenko, Christine Gottschling, Andreas Faissner

“…Moreover, several studies have implicated PNNs and the neural ECM in neuropsychiatric diseases. Here, we highlight current concepts relating to neural ECM and PNNs and describe an in vitro approach that allows for the investigation of ECM functions for synaptogenesis.…”
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Gut Microecological Prescription: A Novel Approach to Regulating Intestinal Micro-Ecological Balance by Zhu L, Yang X

“…Current research reveals intestinal microecological imbalances are related to various diseases. However, fundamental research and clinical applications have not been effectively integrated. …”
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Impact of a Virtual Clinic in a Paediatric Cardiology Network on Northeast Brazil by Juliana Sousa Soares de Araújo, Adalberto Vieira Dias Filho, Renata Grigório Silva Gomes, Cláudio Teixeira Regis, Klecida Nunes Rodrigues, Nicoly Negreiros Siqueira, Fernanda Cruz de Lira Albuquerque, Felipe Alves Mourato, Sandra da Silva Mattos

“…Introduction. Congenital heart diseases (CHD) affect approximately 1% of live births and is an important cause of neonatal morbidity and mortality. …”
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Seroprevalence of Toxoplasma gondii in Wild Rats (Rattus rattus) in Northern Iran by Seyed Abdollah Hosseini, Saeid Abediankenari, Afsaneh Amouei, Shahabeddin Sarvi, Mehdi Sharif, Fatemeh Rezaei, Ahmad Daryani

“…Rodents are considered as reservoir hosts for various pathogens (such as Toxoplasma gondii) and have been revealed to play an important role in the spread of several infectious diseases to humans and other animals. The aim of this investigation was to survey the prevalence of anti-T. gondii IgG antibodies in wild rats in Northern Iran. …”
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Formulation of a Ready-to-Cook Soup Mix Using Microencapsulated Protein Hydrolysate Obtained from Pink Perch By-Product by Asha Kumari, Nutan Kaushik, Rasa Slizyte, Khushboo .

“…However, consumption of fast foods causes malnutrition and nutrition-related diseases. Thus, there is a need to formulate nutrient-rich products that are easy to cook. …”
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Inborn Errors of Immunity Presenting with Early-Onset Severe Atopy by Nipat Chuleerarux, Nadia Makkoukdji, Travis Satnarine, Jessica Elise Kuhn, Tanawin Nopsopon, Peerada Valyasevi, Fernanda Bellodi Schmidt, Gary Kleiner, Melissa Gans

“…This review aims to raise awareness of this association and emphasize the need for early diagnosis and genetic testing in patients with atypical or treatment-resistant allergic diseases, allowing for more timely diagnosis of underlying immunodeficiencies and appropriate treatments.…”
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Phytochemicals, Nutritional and Elemental Composition of different plant parts of Rinorea oblongifolia (C.H Wright) C. Marquand ex Chipp by Adeniyi Ohunayo, Olusola Elekofehinti, Muftau Kolawole Oladunmoye, Anthony Kayode Onifade

“… Antioxidants are essential in managing chronic diseases by neutralizing free radicals and reducing oxidative stress. …”
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Combination of High-Dose Intravenous Immunoglobulins and Itraconozole in Treating Chronic Mycotic Demyelinating Optic Neuritis by Andrew W. Campbell, Ebere C. Anyanwu, Aristo Vojdani

“…Although the health effect of indoor toxic mold on the population worldwide is now one of the �emerging diseases�, its involvement in chronic demyelinating optic neuritis has not been reported. …”
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Optimal Pest Control Strategies with Cost-effectiveness Analysis by Ihza Rizkia Fitri, Farida Hanum, Ali Kusnanto, Toni Bakhtiar

“…Pest and plant diseases cause damages and economic losses, threatening food security and ecosystem services. …”
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Association between Air Pollution and Hemoptysis by Ignasi Garcia-Olive, Joaquim Radua, Jose Antonio Fiz, Jose Sanz-Santos, Juan Ruiz-Manzano

“…The relationship between air pollution and exacerbation of respiratory diseases is well established. Nevertheless, its association with hemoptysis has been poorly investigated. …”
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MicroRNA155 in non-small cell lung cancer: a potential therapeutic target by Xiangju Wei, Xiangju Wei, Xianmin Xiong, Xianmin Xiong, Ze Chen, Bi Chen, Cantang Zhang, Wenhui Zhang

“…Among these, microRNA155(miR-155) is one of the most conserved and versatile miRNAs, predominantly overexpressed in various diseases, including malignant tumors. This review elucidates the biological functions and roles of miR-155 in NSCLC and discusses its potential significance as a therapeutic target for future research directions and clinical applications.…”
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Recent Insights into Antibiotic Resistance in Helicobacter pylori Eradication by Wenming Wu, Yunsheng Yang, Gang Sun

“…Antibiotics have been useful in the treatment of H. pylori-related benign and malignant gastroduodenal diseases. However, emergence of antibiotic resistance often decreases the eradication rates of H. pylori infections. …”
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TDP-43 nuclear retention is antagonized by hypo-phosphorylation of its C-terminus in the cytoplasm by Célia Rabhi, Nicolas Babault, Céline Martin, Bénédicte Desforges, Alexandre Maucuer, Vandana Joshi, Serhii Pankivskyi, Yitian Feng, Guillaume Bollot, Revital Rattenbach, David Pastré, Ahmed Bouhss

“…We anticipate that reducing TDP-43 C-terminus self-assembly in the cytoplasm may be an interesting strategy to reverse TDP-43 nuclear depletion in neurodegenerative diseases.…”
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Niosome Preparation Techniques and Structure—An Illustrated Review by Saeid Mezail Mawazi, Yi Ge, Riyanto Teguh Widodo

“…This is achieved by using a specific charge-inducing agent for drug delivery and targeting specific diseases. These efforts are crucial for overcoming the current limitations and unlocking the full therapeutic potential of modern medicine.…”
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Potent Antioxidative and UVB Protective Effect of Water Extract of Eclipta prostrata L. by Chin-Feng Chan, Wen-Ying Huang, Hong-Yi Guo, Bo Rong Wang

“…Oxidative stress, including Ultraviolet (UV) irradiation-induced skin damage, is involved in numerous diseases. This study demonstrates that water extract of Eclipta prostrata L. …”
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Development of a Reference Method and Materials for Quantitative Measurement of UV-Induced DNA Damage in Mammalian Cells: Comparison of Comet Assay and Cell Viability by Donald H. Atha, Alessandro Tona, Vytas Reipa

“…Application of DNA damage diagnostic tests is rapidly growing, in particular for ovarian, prostate, and skin cancers; environmental monitoring; chronic and degenerative diseases; and male infertility. Such tests suffer from significant variability among different laboratories due the lack of standardization, experimental validation, and differences in data interpretation. …”
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Comments and Illustrations of the European Federation of Societies for Ultrasound in Medicine Guidelines: Benign Pleura Lesions (Benign Pleura Thickening, Lesions and Masses)—What... by Kathleen Möller, Tomas Maruskin, Michael Ludwig, Wolfgang Blank, Stephan Eisenmann, Christian Jenssen, Hajo Findeisen, Burkhard Möller, Christoph F. Dietrich

“…In detail, characteristics in TUS and CEUS are described for infectious/inflammatory pleural thickening (empyema, tuberculous pleuritis, hemothorax, fibrothorax), pleural thickening in various systemic diseases, in tumor-like conditions (plaques, splenosis, endometriosis, mesothelial cysts, lymphangiomatosis) and benign tumors (lipoma, benign SFT, schwannoma, solitary extramedullary/extraosseous plasmacytoma). …”
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