Regulation of noradrenaline synthesis, uptake, and degradation in the left ventricle by fatty acid amide hydrolase (FAAH) inhibitor URB597 in the chronic unpredictable stress model... by Ferizović Harisa, Spasojević Nataša, Janković Milica, Stefanović Bojana, Dronjak Slađana

“…One promising therapeutic strategy for treating different diseases is inhibiting the enzyme fatty acid amide hydrolase (FAAH), which increases the availability of endogenous cannabinoids. …”
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Coordinate Descent-Based Sparse Nonnegative Matrix Factorization for Robust Cancer-Class Discovery and Microarray Data Analysis by Melisew Tefera Belachew

“…Discovering the number of classes in cancer and microarray data plays a vital role in the treatment and diagnosis of cancers and other related diseases. Nonnegative matrix factorization (NMF) plays a paramount role as an efficient data exploratory tool for extracting basis features inherent in massive data. …”
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Genome-wide association study unravels mechanisms of brain glymphatic activity by Shu-Yi Huang, Yi-Jun Ge, Peng Ren, Bang-Sheng Wu, Weikang Gong, Jing Du, Shi-Dong Chen, Ju-Jiao Kang, Qing Ma, Arun L. W. Bokde, Sylvane Desrivières, Hugh Garavan, Antoine Grigis, Herve Lemaitre, Michael N. Smolka, Sarah Hohmann, IMAGEN Consortium, Jian-Feng Feng, Ya-Ru Zhang, Wei Cheng, Jin-Tai Yu

“…Abstract Brain glymphatic activity, as indicated by diffusion-tensor imaging analysis along the perivascular space (ALPS) index, is involved in developmental neuropsychiatric and neurodegenerative diseases, but its genetic architecture is poorly understood. …”
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Rapid and Nondestructive Detection of Proline in Serum Using Near-Infrared Spectroscopy and Partial Least Squares by Kejing Zhu, Shengsheng Zhang, Keyu Yue, Yaming Zuo, Yulin Niu, Qing Wu, Wei Pan

“…It plays an important role in the occurrence and development of diseases. It is of great significance to monitor the metabolism of the machine. …”
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C-SHAP: A Hybrid Method for Fast and Efficient Interpretability by Golshid Ranjbaran, Diego Reforgiato Recupero, Chanchal K. Roy, Kevin A. Schneider

“…Notably, in the Diabetes dataset collected by the National Institute of Diabetes and Digestive and Kidney Diseases, C-SHAP reduces the execution time from nearly 2000 s to just 0.21 s, underscoring its potential for scalable, efficient interpretability in time-sensitive applications. …”
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Distribution of 5-Hydroxymethylcytosine in Different Human Tissues by Weiwei Li, Min Liu

“…Our results showed for the first time that 5-hmC distribution is tissue dependent in human tissues and its abundance could be changed in the diseased states such as colorectal cancer.…”
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An epidemiological modeling investigation of the long-term changing dynamics of the plague epidemics in Hong Kong by Salihu S. Musa, Shi Zhao, Winnie Mkandawire, Andrés Colubri, Daihai He

“…These findings underscore the significance of proactive intervention strategies in managing infectious diseases and informing public health policies.…”
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Amarogentin Displays Immunomodulatory Effects in Human Mast Cells and Keratinocytes by Ute Wölfle, Birgit Haarhaus, Christoph M. Schempp

“…The aim of this study was to assess whether bitter compounds display immunomodulatory effects on these immunocompetent cells in the skin, so that they might be a target in chronic inflammatory diseases such as atopic dermatitis and psoriasis. Here, we investigated the impact of amarogentin on substance P-induced release of histamine and TNF-α from the human mast cell line LAD-2. …”
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Decreased Perifoveal Sensitivity Detected by Microperimetry in Patients Using Hydroxychloroquine and without Visual Field and Fundoscopic Anomalies by A. Molina-Martín, D. P. Piñero, R. J. Pérez-Cambrodí

“…Prospective comparative case series study comprising 14 healthy eyes of 7 patients (group A) and 14 eyes of 7 patients under treatment with hydroxychloroquine for the treatment of rheumatologic diseases and without fundoscopic or perimetric anomalies (group B). …”
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Migratory Polyarthritis Associated With Clopidogrel: A Case Report by Hamid Khederlou, Reza Hassanzadeh-Makoui, Vanoushe Azimi Pirsaraei

“…According to the laboratory investigation, cultures, synovial fluid analysis, and imaging, infectious, rheumatologic, and crystallopathy diseases were ruled out for the patient. Clopidogrel was discontinued, and the patient was switched to ticagrelor 90 mg twice daily. …”
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Antibacterial Potential of Kaempferia parviflora Rhizome Extract against Staphylococcus aureus ATCC 25923 by Dianita Febrina Leswara, Dwi Larasati

“…Bacteria are one of the organisms that cause infectious diseases. One of the bacteria that can cause infection is Staphylococcus aureus. …”
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Diagnostic Features of Common Oral Ulcerative Lesions: An Updated Decision Tree by Hamed Mortazavi, Yaser Safi, Maryam Baharvand, Somayeh Rahmani

“…Various general search engines and specialized databases including PubMed, PubMed Central, Medline Plus, EBSCO, Science Direct, Scopus, Embase, and authenticated textbooks were used to find relevant topics by means of MeSH keywords such as “oral ulcer,” “stomatitis,” and “mouth diseases.” Thereafter, English-language articles published since 1983 to 2015 in both medical and dental journals including reviews, meta-analyses, original papers, and case reports were appraised. …”
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Bone Lid Technique Using a Piezoelectric Device for the Treatment of a Mandibular Bony Lesion by Ronald Younes, Ibrahim Nasseh, Pierre Lahoud, Elie Wassef, Maroun Dagher

“…A complete radiographic bone healing at the previously diseased site was confirmed with an 8-month cone beam computed tomography (CBCT) scan with no buccal bone resorption nor ridge collapse. …”
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Stimulative Effects of Low Intensity He-Ne Laser Irradiation on the Proliferative Potential and Cell-Cycle Progression of Myoblasts in Culture by Cui-Ping Zhang, Shao-Dan Li, Yan Chen, Yan-Ming Jiang, Peng Chen, Chang-Zhen Wang, Xiao-Bing Fu, Hong-Xiang Kang, Ben-Jian Shen, Jie Liang

“…These results suggest that LILI at certain fluences could promote their proliferation, thus contributing to the skeletal muscle regeneration following trauma and myopathic diseases.…”
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Injectable hyaluronic acid-based hydrogel niches to create localized and time-controlled therapy delivery by Veronica Torresan, Alessandro Gandin, Paolo Contessotto, Francesca Zanconato, Giovanna Brusatin

“…In conclusion, this system offers a versatile and efficient delivery platform suitable for therapeutic applications in a wide range of diseases.…”
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Developmental and Epileptic Encephalopathy: Pathogenesis of Intellectual Disability Beyond Channelopathies by Alexandra D. Medyanik, Polina E. Anisimova, Angelina O. Kustova, Victor S. Tarabykin, Elena V. Kondakova

“…Developmental and epileptic encephalopathies (DEEs) are a group of neuropediatric diseases associated with epileptic seizures, severe delay or regression of psychomotor development, and cognitive and behavioral deficits. …”
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Poststroke Cell Therapy of the Aged Brain by Aurel Popa-Wagner, Madalina Filfan, Adriana Uzoni, Pouya Pourgolafshan, Ana-Maria Buga

“…The development of the stem cell (SC), the regenerative therapy field, gained tremendous expectations in the diseases that suffer from the lack of treatment options. …”
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Gene-Gene Interaction Analysis for the Accelerated Failure Time Model Using a Unified Model-Based Multifactor Dimensionality Reduction Method by Seungyeoun Lee, Donghee Son, Wenbao Yu, Taesung Park

“…Although a large number of genetic variants have been identified to be associated with common diseases through genome-wide association studies, there still exits limitations in explaining the missing heritability. …”
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Safe Distance of Virus Quantitative Analysis and Simulation of the Trajectory of Pathogen-Containing Droplets in the Air Respiratory Airways by Hanwen Alvin Miao

“…Droplets of mucosalivary ejecta emitted by sneezing or coughing are a major carrier of numerous types of bacterial and viral diseases. This study develops a numerical model to estimate the spread distance for inhalable droplets (1–50 μm) in the air, the inhalability of the particles, and the trajectory as well as velocity of these pathogen-containing droplets in human respiratory airways. …”
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The Role of von Willebrand Factor in Vascular Inflammation: From Pathogenesis to Targeted Therapy by Felice Gragnano, Simona Sperlongano, Enrica Golia, Francesco Natale, Renatomaria Bianchi, Mario Crisci, Fabio Fimiani, Ivana Pariggiano, Vincenzo Diana, Andreina Carbone, Arturo Cesaro, Claudia Concilio, Giuseppe Limongelli, Mariagiovanna Russo, Paolo Calabrò

“…Moreover, VWF and ADAMTS13 have been recently proposed as prognostic biomarkers in cardiovascular, metabolic, and inflammatory diseases, such as diabetes, stroke, myocardial infarction, and sepsis. …”
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