Advances and Challenges in Antiviral Development for Respiratory Viruses by Luis Adrián De Jesús-González, Moisés León-Juárez, Flor Itzel Lira-Hernández, Bruno Rivas-Santiago, Manuel Adrián Velázquez-Cervantes, Iridiana Monserrat Méndez-Delgado, Daniela Itzel Macías-Guerrero, Jonathan Hernández-Castillo, Ximena Hernández-Rodríguez, Daniela Nahomi Calderón-Sandate, Willy Salvador Mata-Martínez, José Manuel Reyes-Ruíz, Juan Fidel Osuna-Ramos, Ana Cristina García-Herrera

“…Combining traditional and advanced approaches in developing antivirals is essential in order to address respiratory viral diseases that affect global health.…”
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Levothyroxine malabsorption following sleeve gastrectomy by Elodie Gruneisen, Ji Wei Yang, Melissa-Rosina Pasqua

“…Bariatric surgery for patients with obesity has shown a substantial, long-term weight loss and considerable improvement of obesity-related diseases. LT4 malabsorption represents a significant cause of refractory hypothyroidism, well known after malabsorptive bariatric surgery such as Roux-en-Y gastric bypass. …”
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Organization of hospital services for an outbreak of arboviral infections. Cienfuegos 2018 by Carlos García Gómez, María Ocavina Rodríguez Roque, Viviana García Escudero, Andrés Pável Peña Batista, Mailé Ramírez Martínez, Onel Rodríguez Chávez

“…<p><strong>Foundation:</strong> arbovirus infections are among the main diseases that affect tropical regions. Within this group, dengue plays a preponderant role. …”
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Disseminated Intravascular Coagulation and Malignancy: A Case Report and Literature Review by Sumit Sohal, Akhilesh Thakur, Aleena Zia, Mina Sous, Daniela Trelles

“…Disseminated Intravascular Coagulation (DIC) is a disorder of coagulation which is commonly seen as a complication of infections, traumas, obstetric diseases, and cancers especially hematological and rarely solid cancers. …”
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Quantitative Detection of Amino Acids and Carnitine in Human Blood and Quality Control of Peptide Drugs by Yuchun Ma, Yujie Zhu, Zhengqing Lu, Huiqing Hu, Jinmei Li, Shangqing Yang, Jiaru Han

“…In order to deal with the biochemical metabolic disorder and the lack of end metabolites caused by hereditary metabolic diseases, a quantitative detection method of amino acids and carnitine in human blood and the quality control method of polypeptide drugs were proposed. …”
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HCV and Lymphoproliferation by Anna Linda Zignego, Carlo Giannini, Laura Gragnani

“…It is not only a hepatotropic but also a lymphotropic agent and is responsible not only for liver injury—potentially evolving to cirrhosis and hepatocellular carcinoma—but also for a series of sometimes severely disabling extrahepatic diseases and, in particular, B-cell lymphoproliferative disorders. …”
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Long-Term Effectiveness of Parent Education Using the “Baby Oral Health” Model on the Improvement of Oral Health of Young Children by Gajanan V. Kulkarni

“…To determine the long-term effectiveness of comprehensive education given to parents and caregivers with respect to the incidence of preventable oral diseases, utilization of dental services, and retention of knowledge related to oral health. …”
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The Mechanism of Metabolic Influences on the Endogenous GLP-1 by Oral Antidiabetic Medications in Type 2 Diabetes Mellitus by Thiquynhnga Nguyen, Min Gong, Song Wen, Xinlu Yuan, Chaoxun Wang, Jianlan Jin, Ligang Zhou

“…For this reason, it is recommended for individuals with cardiovascular diseases in many clinical guidelines. As an incretin hormone, glucagon-like peptide-1 (GLP-1) possesses multiple metabolic benefits such as optimizing energy usage, maintaining body weight, β cell preservation, and suppressing neurodegeneration. …”
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Portal-splenic-mesenteric venous thrombosis in COVID-19 patients: a systematic review by Ricardo Zanetti Gomes, Matheus Von Jelita Salina, Vitor Hugo Moro Pironatto, Julia Kapp Lepinski, Tiago Daniel Gueiber, Beatriz Moreira Salles Juliatto, Milena Zadra Prestes, Camila Marinelli Martins

“…Males were more prevalent (n=27; 65.85%), mean age was 51.54 years, and 19.57% had a previous history of endocrine diseases. Statistically significant relationships (p<0.05) were found between patient death and tachypnea at hospital admission (p=0.043) and between patient death and age (p=0.019). …”
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Oxidative Stress and DNA Methylation in Prostate Cancer by Krishna Vanaja Donkena, Charles Y. F. Young, Donald J. Tindall

“…Epigenetics affects genetic regulation, cellular differentiation, embryology, aging, cancer, and other diseases. DNA methylation is perhaps the most extensively studied epigenetic modification, which plays an important role in the regulation of gene expression and chromatin architecture, in association with histone modification and other chromatin-associated proteins. …”
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A Beginner’s Guide to Water Management—Fish Kills by Florida LAKEWATCH

“… In an effort to alleviate concerns voiced by the general public, the Florida LAKEWATCH (FLW) program published this 16-page booklet that discusses five of the most common natural causes of fish kills including: low dissolved oxygen; spawning fatalities; mortality due to cold temperatures; diseases and parasites; and toxic algae blooms. Human-induced fish kills are also covered along with a section on fish stress—a component of virtually every fish kill situation. …”
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Acute Eosinophilic Ascites in a Middle-Aged Man by Fadi Bleibel, Keith Fragoza, Garrey T. Faller

“…Its etiology and pathogenesis remain unclear and its symptoms overlap with many GI and systemic diseases. Thus, both gastroenterologists and general internists need to be aware of this rare condition. …”
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Acoustic Angiography: A New Imaging Modality for Assessing Microvasculature Architecture by Ryan C. Gessner, C. Brandon Frederick, F. Stuart Foster, Paul A. Dayton

“…We present a brief technical overview of how the images are acquired, followed by several examples of images of both healthy and diseased tissue volumes. 3D images from alternate modalities often used in preclinical imaging, contrast-enhanced micro-CT and photoacoustics, are also included to provide a perspective on how acoustic angiography has qualitatively similar capabilities to these other techniques. …”
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Anti-Inflammatory Effects of Epoxyeicosatrienoic Acids by Scott J. Thomson, Ara Askari, David Bishop-Bailey

“…In particular, numerous studies have demonstrated that potentiation of EET activity using different methods can inhibit inflammatory gene expression and signalling pathways in endothelial cells and monocytes and in models of cardiovascular diseases. The mechanisms by which EETs mediate their effects are largely unknown but may include direct binding to peroxisome proliferator-activated receptors (PPARs), G-protein coupled receptors (GPCRs), or transient receptor potential (TRP) channels, which initiate anti-inflammatory signalling cascades.…”
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Antibodies to Cardiolipin in Patients with Primary Biliary Cirrhosis by John Verrier Jones, Dianne P. Mosher, Edith Jones, C. Noel Williams, Dickran Malatjalian, Roland I. Carr, Mervat Mansour

“…Thus far they have been found to be less prevalent in other diseases. Because of the high concentration of cardiolipin in mitochondrial membranes and the presence of antimitochondrial antibodies in patients with primary biliary cirrhosis, the authors investigated the prevalence of antibodies to cardiolipin in a group of 31 patients with primary biliary cirrhosis. lt was found that the prevalence and levels of anticardiolipin antibodies of lgG and lgA isotype are as high in patients with primary biliary cirrhosis as in 35 consecutive patients with systemic lupus erythematosus. …”
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Feature Extraction Processing Method of Medical Image Fusion Based on Neural Network Algorithm by Tianming Song, Xiaoyang Yu, Shuang Yu, Zhe Ren, Yawei Qu

“…It not only provides important information about internal organs of the body for clinical analysis and medical treatment but also assists doctors in diagnosing and treating various diseases. However, in the process of medical image feature extraction, there are some problems, such as inconspicuous feature extraction and low feature preparation rate. …”
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Postpartum Exudation of Idiopathic Quiescent Macular Neovascularization: A Narrative Review with a Related Case Report by Livio Vitiello, Maddalena De Bernardo, Ilaria De Pascale, Giulio Salerno, Alfonso Pellegrino, Nicola Rosa

“…In addition, MNV can be found in people under 50 years of age, who may present primary ophthalmic diseases such as pathological myopia, angioid streaks, traumatic choroidal rupture, or suspected ocular histoplasmosis syndrome. …”
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Amperometric Biosensor Detecting Dopamine Based on Polypyrrole/Reduced Graphene Oxide/Nickel Oxide/Glassy Carbon Electrode by Shindy Ayu Netania Priyanto, Elly Septia Yulianti, Ahmad Zakiyuddin, Siti Fauziyah Rahman

“…However, abnormal levels of DA in the brain can lead to Parkinson’s, Alzheimer’s, or schizophrenia diseases. A biosensor is defined as an analytical tool that combines certain biological recognition components with a physical transducer. …”
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Mesona chinensis Benth polysaccharides alleviates liver injury by beneficial regulation of gut microbiota in cyclophosphamide-induced mice by Yuzhen Hong, Mingyue Shen, Lixin Huang, Ting Wu, Jianhua Xie

“…In short, the prevention of CTX-induced liver injury by supplementing MP is achieved at least in part by regulating the community structure of the gut microbiota, and MP is expected to be a potential prebiotic to treat and prevent liver diseases.…”
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Mathematical rules for synergistic, additive, and antagonistic effects of multi-drug combinations and their application in research and development of combinatorial drugs and speci... by Shoujun Yuan, Haoyu Chen

“…The main motivations for these combinations are that most diseases contain multiple related targets and an appropriate combination can maximize benefits while minimizing adverse reactions. …”
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