Emerging Stem Cell Therapies: Treatment, Safety, and Biology by Joel Sng, Thomas Lufkin

“…Hematopoietic stem cell transplantation was the first example of a successful stem cell therapy and is widely utilized for treating various diseases including adult T-cell leukemia-lymphoma and multiple myeloma. …”
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Nanobody-thioesterase chimeras to specifically target protein palmitoylation by Chien-Wen Kuo, Caglar Gök, Hannah Fulton, Eleanor Dickson-Murray, Samuel Adu, Emily K. Gallen, Sheon Mary, Alan D. Robertson, Fiona Jordan, Emma Dunning, William Mullen, Godfrey L. Smith, William Fuller

“…The temporal and spatial control of these PTMs is central to organism physiology, and mis-regulation of PTMs is a hallmark of many diseases. Here we present an approach to manipulate PTMs on target proteins using nanobodies fused to enzymes that control these PTMs. …”
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Metabolic engineering approaches for the biosynthesis of antibiotics by Geunsoo Yook, Jiwoo Nam, Yeonseo Jo, Hyunji Yoon, Dongsoo Yang

“…Abstract Background Antibiotics have been saving countless lives from deadly infectious diseases, which we now often take for granted. However, we are currently witnessing a significant rise in the emergence of multidrug-resistant (MDR) bacteria, making these infections increasingly difficult to treat in hospitals. …”
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Chemokines and Neurodegeneration in the Early Stage of Experimental Ischemic Stroke by Pawel Wolinski, Andrzej Glabinski

“…Recently inflammation has been implicated in pathogenesis of neurodegeneration and neurodegenerative diseases. The aim of this study was analysis of expression of several inflammatory markers and its correlation with development of neurodegeneration during the early stage of experimental stroke. …”
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Does SIRT-1 Mediate Calorie Restriction and Prolong Life? – A Mini Review by Kordala Anna, Pietrzak Bogusława

“…Not only does the regimen prolong life, but it also reduces the incident of numerous age-related diseases like diabetes, atherosclerosis or cancer and slows down ageing. …”
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A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in Bangladesh by Zahurul Islam, K. M. Ariful Kabir, M. M. Rahman, Md. Atikur Rahman

“…An objective function has been regarded as a cost function introduced by the optimal controls and the diseases themselves. Then, the existence and uniqueness of the optimal system have also been shown with the help of Pontryagin’s minimum principle. …”
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TOXICOLOGIC CHARACTERISTICS OF THE PREVENTIVE IODINE-CONTAINING PREPARATION “VANGTSEYOD” by T. V. Kruchinkina, Yu. A. Gavrilov, G. A. Gavrilova

“…The Amur Oblast belongs to biogeochemical province with low contents of iodine in the soil, water and air, which leads to the thyroid gland disorders in animals, weakened immunity system and, consequently, to the increased sensitivity to diseases. A new iodinecontaining preparation “Vangtseyod” has been developed basing on natural zeolites from Vanga deposits to prevent iodine deficit in young cattle. …”
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Highly Amplified Broadband Ultrasound in Antiresonant Hollow Core Fibers by Ricardo E. da Silva, David John Webb, Cristiano Monteiro de Barros Cordeiro, Marcos Antonio Ruggieri Franco

“…The results are a significant advance for fiber‐based ultrasonic sensors and transmitters, contributing to improve their efficiency and microscale spatial resolution for the detection, diagnosis, and treatment of diseases in biomedical applications.…”
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Case Control Analyses of Acute Endophthalmitis after Cataract Surgery in South India Associated with Technique, Patient Care, and Socioeconomic Status by Taraprasad Das, Anjli Hussain, Thomas Naduvilath, Savitri Sharma, Subhadra Jalali, Ajit B. Majji

“…In addition, we analyzed systemic diseases, surgeon factor, habitat, and socioeconomic status. …”
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Knowledge and attitude factors as determinants of pregnant women’s participation in triple elimination program in North Bali by Sekarini Ni Nyoman Ayu Desy, Yanti Linda, Pratiwi Putu Irma

“…The WHO reports that 1.5 million children die annually from diseases that may have been avoided if they had received the vaccination, highlighting the broader public health implications. …”
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Cytokines and HCV-Related Disorders by Poupak Fallahi, Clodoveo Ferri, Silvia Martina Ferrari, Alda Corrado, Domenico Sansonno, Alessandro Antonelli

“…The most important systemic HCV-related extrahepatic diseases—mixed cryoglobulinemia, lymphoproliferative disorders, thyroid autoimmune disorders, and type 2 diabetes—are associated with a complex dysregulation of the cytokine/chemokine network, involving proinflammatory and Th1 chemokines. …”
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Experimental and numerical study of cemented bone-implant interface behavior by D. Kytyr, T. Doktor, O. Jirousek, P. Zlamal, D. Pokorny

“…Although the total hip replacement (THR) is a long-proven method of surgical treatment of diseases and disorders of the human hip, the surgery brings some risk of long-term instability of the joint. …”
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A critical review on the health promoting effects of mushrooms nutraceuticals by Gaoxing Ma, Wenjian Yang, Liyan Zhao, Fei Pei, Donglu Fang, Qiuhui Hu

“…The present article overviewed and compiled the latest information correlated to the health benefits and underlying functional mechanisms of mushroom nutraceuticals, and concluded that the supplementation of mushrooms as a dietary composition could become a natural adjuvant for the prevention and treatment of several health diseases. Keywords: Mushrooms, Bioactive nutraceuticals, Health benefits, Functional mechanisms, Gut microbiota regulation…”
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Sepsis and Pleural Empyema Caused by Streptococcus pyogenes after Influenza A Virus Infection by Fumihiro Ochi, Hisamichi Tauchi, Toshihiro Jogamoto, Hiromitsu Miura, Tomozo Moritani, Kozo Nagai, Eiichi Ishii

“…Streptococcus pyogenes (also referred to as group A streptococci, GAS) causes severe invasive diseases such as bacteremia, necrotizing fasciitis, pneumonia, osteomyelitis, septic arthritis, and toxic shock syndrome in children. …”
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Spontaneous Intraperitoneal Rupture of Bladder Diverticulum: A Rare Cause of Peritonitis by Ahmed Ibrahimi, Adil Kallat, Idriss Ziani, Hachem El Sayegh, Lounis Benslimane, Yassine Nouini

“…The prognosis depends on the earliness of treatment, associated comorbidity, and the nature of underlying diseases. Herein, we report a rare case of a 65-year-old male patient, who presented a spontaneous rupture of a large acquired bladder diverticulum, secondary to acute urinary retention complicating benign prostatic hypertrophy. …”
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Enhanced Depth Imaging Optical Coherence Tomography: A New Way Measuring Choroidal Thickness in Pregnant Women by Jun Zhang, Huiyun Wang, Qiubo Yu, Qihu Tong, Qinkang Lu

“…As the optical coherence tomography develops, a rapid, direct, noninvasive, and nontoxic way is available to obtain the choroid situation of pregnant women, which may explain the mechanism of pregnancy-related eye diseases. This review would summarize relevant original articles published from January 1, 2008 to December 1, 2016 to assess the changes of choroidal thickness (CT) with enhanced depth imaging optical coherence tomography (EDI-OCT) during pregnancy. …”
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Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets by Sanya Arshad, Benjamin Cameron, Alok V. Joglekar

“…In several autoimmune diseases, immunopeptidomics has led to the identification of novel autoantigens and has enhanced our understanding of the mechanisms behind autoimmunity. …”
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Characterization of Human Mesenchymal Stem Cells Isolated from the Testis by Letizia De Chiara, Elvira Smeralda Famulari, Sharmila Fagoonee, Saskia K. M. van Daalen, Stefano Buttiglieri, Alberto Revelli, Emanuela Tolosano, Lorenzo Silengo, Ans M. M. van Pelt, Fiorella Altruda

“…We further demonstrate, for the first time, that tMSCs are able to secrete microvesicles that could possibly be applied to the treatment of various chronic diseases, such as those affecting the kidney.…”
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Successful Management of Immune Thrombocytopenia Presenting with Lethal Alveolar Hemorrhage by Keiki Nagaharu, Masahiro Masuya, Keiki Kawakami, Naoyuki Katayama

“…These patients had the following underlying pulmonary diseases: case 1, nontuberculous mycobacterial infection and sarcoidosis; case 2, cryptogenic organizing pneumonia; case 3, pulmonary emphysema. …”
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Pulse protein quality and derived bioactive peptides by Matthew G. Nosworthy, Matthew G. Nosworthy, Bianyun Yu, L. Irina Zaharia, Gerardo Medina, Nii Patterson

“…Overall, the high nutritional quality of pulse-based proteins supports the benefits of pulse inclusion in the diet, which can also exert beneficial bioactivities resulting in improving outcomes in non-communicable diseases.…”
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