O 'combate' às doenças tropicais na imprensa colonial alemã 'Combating' tropical diseases in the German colonial press by Sílvio Marcus de Souza Correa

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T cells in ARAP-deficient mice present defective T cell receptor signaling and reduced severity in an experimentally-induced autoimmune disease by Jee-Hae Kim, Seung Hee Jung, Chohee Park, Jong Ran Lee

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Missing the mark(ers): circulating endothelial cells and endothelial-derived extracellular vesicles are elevated in sickle cell disease plasma by Joan D. Beckman, Ping Zhang, Julia Nguyen, Robert P. Hebbel, Gregory M. Vercellotti, John D. Belcher

“…Sickle cell disease (SCD) is a devastating hemolytic disease, marked by recurring bouts of painful vaso-occlusion, leading to tissue damage from ischemia/reperfusion pathophysiology. …”
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Lignans-rich extract of Schisandra chinensis prevent alcohol-associated liver disease by regulating the gut microbiota and tryptophan metabolism by Yan-Yu Chi, Jun-Yan Xiang, Hui-Min Li, Hao-Yu Shi, Ke Ning, Hongyu Xiang, Qiuhong Xie

Subjects: “…Alcohol-associated liver disease…”
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Relationship between dietary acid-base load and non-insulin-based resistance measures in patients with chronic kidney disease by Hui Huang, Hui Huang, Qian Wang, Ruimin Zhang, Fang Liu, Fang Liu, Yue Niu, Yayong Luo, Junqian Wang, Junqian Wang, Shuang Li, Zhengchun Tang, Zhengchun Tang, Xueying Cao, Xiaolong Wang, Jian Yang, Sha Luo, Weizhu Deng, Weiguang Zhang, Ying Zheng, Yong Wang, Li Zhang, Guangyan Cai, Xiangmei Chen, Xiangmei Chen, Xiangmei Chen, Zheyi Dong

Subjects: “…chronic kidney disease…”
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The immunogenicity and safety of an inactivated quadrivalent influenza vaccine and a 23-valent pneumococcal polysaccharide vaccine in individuals with chronic diseases by Wanqin Tang, Xi Lu, Zhongkui Zhu, Dan Yu, Huaxian Liu, Yufei Song, Lu Shen, Yang Yu, Yanwei Zhao, Yan Xie

Subjects: “…chronic disease…”
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Quantification and Comprehensive Analysis of Mesenchymal Stromal Cells in Bone Marrow Samples from Sickle Cell Disease Patients with Osteonecrosis by Tiago O. Ribeiro, Paula B. Daltro, Gildasio Cerqueira Daltro, Songeli M. Freire, Roberto Meyer, Vitor Fortuna

“…The potential use of bone marrow mesenchymal stromal cells (BM-MSCs) for the treatment of osteonecrosis in sickle cell disease (SCD) patients is increasing. However, convenient BM-MSC quantification and functional property assays are critical factors for cell-based therapies yet to be optimized. …”
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Genetic characterization of genotype VII.1.1 Newcastle Disease viruses from commercial and backyard broiler chickens in Egypt by Abdelmonem Dewidar, Azza El-Sawah, Salama Shany, Al-Hussien Dahshan, Ahmed Ali

“…The current study was conducted to investigate and molecularly characterize Newcastle Disease (ND) strains circulating in small-scale and backyard poultry sectors in Giza governorate in Egypt from July 2018 to April 2020. …”
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Palbociclib and letrozole for hormone receptor-positive HER2-negative breast cancer with residual disease after neoadjuvant chemotherapy by Sonia Pernas, Esther Sanfeliu, Guillermo Villacampa, Javier Salvador, Antonia Perelló, Xavier González, Begoña Jiménez, María Merino, Patricia Palacios, Tomás Pascual, Emilio Alba, Lorea Villanueva, Samyukta Chillara, Juan Manuel Ferrero-Cafiero, Patricia Galvan, Aleix Prat, Eva Ciruelos

“…Trial registration: Palbociclib Plus Letrozole in Hormone Receptor Positive Residual Disease After Neoadjuvant Chemotherapy (PROMETEO II) ClinicalTrial.gov number NCT04130152. …”
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Chronic Inflammation and Immune Dysregulation in Metabolic-Dysfunction-Associated Steatotic Liver Disease Progression: From Steatosis to Hepatocellular Carcinoma by Young-Min Jee, Jeong-Yoon Lee, Tom Ryu

Subjects: “…metabolic-dysfunction-associated steatotic liver disease…”
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Factors Associated with Multibacillary Leprosy in a Priority Region for Disease Control in Northeastern Brazil: A Retrospective Observational Study by Maria Aparecida Alves de Oliveira Serra, Crislane da Silva Santos, Pedro Martins Lima Neto, Karyne Gleyce Zemf Oliveira, Francisca Jacinta Feitoza de Oliveira, Ariadne Siqueira de Araujo Gordon, Daniella Pontes Matos, Raina Jansen Cutrim Propp Lima, Janaina Miranda Bezerra, Ismália Cassandra Costa Maia Dias, Floriacy Stabnow Santos, Ana Cristina Pereira de Jesus Costa, Marcelino Santos Neto, Antônio Rafael da Silva, Márcio Flávio Moura de Araújo

“…Leprosy is an infectious disease that can lead to physical disabilities and stigmatization. …”
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MMP-3 Contributes to Nigrostriatal Dopaminergic Neuronal Loss, BBB Damage, and Neuroinflammation in an MPTP Mouse Model of Parkinson’s Disease by Young Cheul Chung, Yoon-Seong Kim, Eugene Bok, Tae Young Yune, Sungho Maeng, Byung Kwan Jin

“…These data suggest that MMP-3 could play a crucial role in neurodegenerative diseases such as PD in which BBB damage and neuroinflammation are implicated.…”
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The autocrine motility factor receptor delays the pathological progression of Alzheimer’s disease via regulating the ubiquitination-mediated degradation of APP by Jingjing Zhang, Congcong Liu, Jing Liu, Yuting Cui, Yuli Hou, Qiao Song, Xiaomin Zhang, Xiaoling Wang, Qian Zhang, Min Cao, Wenchao Wang, Peichang Wang, Yaqi Wang

Subjects: “…Alzheimer’s disease…”
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COMMENTS TO THE ARTICLE BY E.I. KONDRATYEVA ET AL. «CLINICAL AND GENETIC PARALLELS IN CELIAC DISEASE AMONG TOMSK CHILDREN» by A.Yu. Asanov

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Socio-Economic and Scientific Impact Created by Whitefly-Transmitted, Plant-Virus Disease Resistant Tomato Varieties in Southern India by John Colvin, N Nagaraju, Carlos Moreno-Leguizamon, RM Govindappa, TB Manjunatha Reddy, SA Padmaja, Neena Joshi, Peter M Hanson, Susan E Seal, V Muniyappa

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Protocol for an observational study to identify potential predictors of an acute exacerbation in patients with chronic obstructive pulmonary disease (the PACE Study) by Klaus Kenn, Paul W Jones, Carmen Schade-Brittinger, Rainer Gloeckl, Daniela Leitl, Tessa Schneeberger, Inga Jarosch, Wolfgang Hitzl, Peter Alter, Bernd Sczepanski, Sandra Winterkamp, Martina Boensch, Chrysanthi Skevaki, Olaf Holz, Claus F Vogelmeier, Andreas R Koczulla

“…Introduction Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are the most critical events for patients with COPD that have a negative impact on patients’ quality of life, accelerate disease progression, and can result in hospital admissions and death. …”
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Perspectives of Clients and Health Care Professionals on the Opportunities for Digital Health Interventions in Cerebrovascular Disease Care: Qualitative Descriptive Study by Henna Härkönen, Kirsi Myllykangas, Mikko Kärppä, Kirsi Maaria Rasmus, Julius Francis Gomes, Milla Immonen, Piia Hyvämäki, Miia Jansson

“… BackgroundCerebrovascular diseases (CVDs) are a major and potentially increasing burden to public health. …”
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The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non‐alcoholic fatty liver disease by Cheng Zhang, Elias Bjornson, Muhammad Arif, Abdellah Tebani, Alen Lovric, Rui Benfeitas, Mehmet Ozcan, Kajetan Juszczak, Woonghee Kim, Jung Tae Kim, Gholamreza Bidkhori, Marcus Ståhlman, Per‐Olof Bergh, Martin Adiels, Hasan Turkez, Marja‐Riitta Taskinen, Jim Bosley, Hanns‐Ulrich Marschall, Jens Nielsen, Mathias Uhlén, Jan Borén, Adil Mardinoglu

“…Abstract The prevalence of non‐alcoholic fatty liver disease (NAFLD) continues to increase dramatically, and there is no approved medication for its treatment. …”
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On the issue of introducing an electronic database of children with oncological diseases into specialized medical organizations: results of a medical and social research by M. Yu. Rykov, O. A. Manerova

“…Our aim was to study the opinions of pediatric oncologists on the issues of registration of children with oncological diseases.Materials and methods. In order to assess the results of the implementation of the electronic database, a "Questionnaire for a survey of a pediatric oncologist to assess the effectiveness of the implementation of an electronic database" was developed, which contained 15 questions. …”
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Experimental investigations of application of the water-steam оzone-containing gaseous mixture for prophylaxis and treatment of respiratory infectious diseases by M. V. Kostylev, S. L. Rybalko, A. A. Vladimirov, N. V. Chukhraiev, G. V. Terehov, S. N. Titarenko, D. B. Starosila, I. M. Savytska, O. A. Geylenko

Subjects: “…the water-steam ozone-containing mixture; polyetiological respiratory diseases; virus of transmissive gastroenteritis of pigs; family of coronaviruses.…”
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