Invasive Klebsiella pneumoniae liver abscess syndrome complicated by carbapenem-resistant Acinetobacter baumannii infection: a case report by Qiupeng Feng, Qiupeng Feng, Hua Yuan, Hua Yuan, Jin Ma, Jin Ma, Zhiqiang Guo, Zhiqiang Guo, Xiaohua Xia, Xiaohua Xia, Guang Zhao, Guang Zhao

“…This condition, known as Klebsiella pneumoniae liver abscess invasion syndrome, progresses rapidly and is associated with severe illness, high disability rates, and significant mortality. However, bloodstream infections with co-infection involving carbapenem-resistant Acinetobacter baumannii are exceedingly rare.Case presentationThe Emergency Medicine Department of the First People’s Hospital of Kunshan successfully treated a male patient diagnosed with liver, lung, and prostate abscesses. …”
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Effects of Genipin Concentration on Cross-Linked Chitosan Scaffolds for Bone Tissue Engineering: Structural Characterization and Evidence of Biocompatibility Features by Simona Dimida, Amilcare Barca, Nadia Cancelli, Vincenzo De Benedictis, Maria Grazia Raucci, Christian Demitri

“…Also, the degradation rate was shown to decrease while increasing the cross-linking degree, with the high cross-linking density of the scaffold disabling the hydrolysis activity. Finally, basic biocompatibility was investigated in vitro, by evaluating proliferation of two human-derived cell lines, namely, the MG63 (human immortalized osteosarcoma) and the hMSCs (human mesenchymal stem cells), as suitable cell models for bone tissue engineering applications of biomaterials.…”
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Partial Facetectomy for Lumbar Foraminal Stenosis by Kevin Kang, Juan Carlos Rodriguez-Olaverri, Frank Schwab, Jenifer Hashem, Afshin Razi, Jean Pierre Farcy

“…Several different techniques exist to address the pain and disability caused by isolated nerve root impingement. …”
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Connecting Cerebral White Matter Lesions and Hypertensive Target Organ Damage by Cristina Sierra, Alfons López-Soto, Antonio Coca

“…Stroke is the second leading cause of death and the number one cause of disability worldwide and over 80% of strokes occur in the elderly. …”
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Life and last year prevalence of psychiatric disorders in primary level of care in a region of southern Chile by Ximena Macaya, Esteban Moraga-Escobar, Paola Lagos Muñoz, Romina Rojas Ponce, Kristin Schmidt, Alejandra Guzmán-Castillo, Sandra Saldivia, Benjamín Vicente, Juan Luis Castillo-Navarrete

“…Health service care is high among people with mental disorders; likewise, it has been established that mental disorders represent around 6% of all disability-adjusted life years lost worldwide. Objective: To identify the lifetime and last-year prevalence of mental disorders in the population assisted at the primary health care level in a city in southern Chile. …”
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Delays in Blood Work and Disease Burden: A Cross-Sectional Analysis of Unmet Blood Work Need and Seven Key Health Conditions Across 21 Countries by Eunice Chung, Louisa Ewald, Nicholas J. Kassembaum, Nicholas J. Kassembaum, Taylor Noyes, Emmanuela Gakidou, Emmanuela Gakidou, Ali H. Mokdad, Ali H. Mokdad

“…We also examined the disease burden using disability-adjusted life years (DALYs) and summary exposure values (SEV) rates.ResultsOur findings indicate profound disparities, with over 60% of respondents in Egypt, Nigeria, and India reporting they have never undergone blood tests. …”
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Attitudes Regarding the Use of Ventilator Support Given a Supposed Terminal Condition among Community-Dwelling Mexican American and Non-Hispanic White Older Adults: A Pilot Study by M. Rosina Finley, Johanna Becho, R. Lillianne Macias, Robert C. Wood, Arthur E. Hernandez, David V. Espino

“…Being first or second generation American (OR = 0.18, CI = 0.05–0.66) with no IADL disability (OR = 0.11, CI = 0.02–0.59) and having depressive symptoms (OR = 1.43, CI = 1.08–1.89) were associated with preference for ventilator support. …”
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Age-related and Gender Aspects of Inflammatory Bowel Diseases in the Republic of Dagestan by S. Sh. Akhmedkhanov, G. H. Abakarova, A. T. Beibalayeva, B. S. Abdullayeva, Z. M. Saidova

“…Anemia (mainly chronic iron deficiency) was registered in 66.1 %, more often in women, its maximum frequency was noted in patients aged 20–29 years (80 %). Disability due to IBD was registered in 55.4 % of patients.Conclusions. …”
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Paroxysmal sympathetic hyperactivity in brain damage (scientific review). Part 1 by O.V. Kravets, V.A. Sedinkin, V.V. Yekhalov, Yu.O. Ploshchenko, O.O. Zozulya

“…Hypodiagnosis of PSH can lead to an increase in mortality, disability, length of hospital stay and material costs, but timely diagnosis will allow optimizing treatment for PSH.…”
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Genomic Copy Number Variation Affecting Genes Involved in the Cell Cycle Pathway: Implications for Somatic Mosaicism by Ivan Y. Iourov, Svetlana G. Vorsanova, Maria A. Zelenova, Sergei A. Korostelev, Yuri B. Yurov

“…Here, we have evaluated genomic copy number variation (CNV) in genes implicated in the cell cycle pathway (according to Kyoto Encyclopedia of Genes and Genomes/KEGG) within a cohort of patients with intellectual disability, autism, and/or epilepsy, in which the phenotype was not associated with genomic rearrangements altering this pathway. …”
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Improving Cognitive Function after Traumatic Brain Injury: A Clinical Trial on the Potential Use of the Semi-Immersive Virtual Reality by Rosaria De Luca, Maria Grazia Maggio, Giuseppa Maresca, Desiree Latella, Antonino Cannavò, Francesca Sciarrone, Emanuele Lo Voi, Maria Accorinti, Placido Bramanti, Rocco Salvatore Calabrò

“…Traumatic brain injury (TBI) is the most common cause of long-term disability and death among young adults, and it represents an enormous socioeconomic and healthcare burden. …”
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Identifying Key Biomarkers and Immune Infiltration in Female Patients with Ischemic Stroke Based on Weighted Gene Co-Expression Network Analysis by Haipeng Xu, Kelin He, Rong Hu, YanZhi Ge, Xinyun Li, Fengjia Ni, Bei Que, Yi Chen, Ruijie Ma

“…Stroke is one of the leading causes of death and disability worldwide. Evidence shows that ischemic stroke (IS) accounts for nearly 80 percent of all strokes and that the etiology, risk factors, and prognosis of this disease differ by gender. …”
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Management of Rett Syndrome in the Controlled Multisensory (Snoezelen) Environment. A Review with Three Case Stories by Meir Lotan

“…It is characterized by a variety of physical and perceptual disabilities, resulting in a need for continuous intervention programs to be administered on a regular basis throughout life. …”
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Clinical Application of Autologous Adipose Stem Cells in Patients with Multiple Sclerosis: Preliminary Results by Adam Stepien, Natalia L. Dabrowska, Marzena Maciagowska, Renata Piusinska Macoch, Aleksandra Zolocinska, Slawomir Mazur, Katarzyna Siennicka, Emilia Frankowska, Rafał Kidzinski, Małgorzata Chalimoniuk, Zygmunt Pojda

“…Neither the progression of disability nor relapses were observed in any cases. …”
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Electric field stimulation directs target-specific axon regeneration and partial restoration of vision after optic nerve crush injury. by Timothy Kim, Ege Iseri, Micalla G Peng, Sasha Medvidovic, Timothy Silliman, Pooyan Pahlavan, Gengle Niu, Connie Huang, Anahit Simonyan, Javad Pahnahad, Petcy Yao, Phillip Lam, Vahini Garimella, Mahnaz Shahidi, Michael S Bienkowski, Darrin J Lee, Biju Thomas, Gianluca Lazzi, Kimberly K Gokoffski

“…Failure of central nervous system (CNS) axons to regenerate after injury results in permanent disability. Several molecular neuro-protective and neuro-regenerative strategies have been proposed as potential treatments but do not provide the directional cues needed to direct target-specific axon regeneration. …”
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Neuroinflammation and Oxidative Stress in Diabetic Neuropathy: Futuristic Strategies Based on These Targets by Reddemma Sandireddy, Veera Ganesh Yerra, Aparna Areti, Prashanth Komirishetty, Ashutosh Kumar

“…Among the vascular complications of diabetes, diabetic neuropathy is the most painful and disabling, fatal complication affecting the quality of life in patients. …”
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Off-Label Use of Intravenous Immunoglobulin with Methylprednisolone to Treat Parsonage–Turner Syndrome in a United States Marine by Carissa M. Sedlacek, Michael Leone, Adam D. Foster, Amy Hinkelman

“…Full functional recovery can take months to years, but recurrence and/or persistence of symptoms and disability are frequent. This case reports a 22-year-old male who recovered from NA within 3 months following treatment with 1000 mg of methylprednisolone and off-label use of 0.5 g/kg of intravenous immunoglobulins (IVIG) for four consecutive days. …”
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The IVIG treatment response in autoimmune polyendocrine syndromes type 2 with anti-GAD65 antibody-associated stiff person syndrome: a case report and literature review by Yulong Yang, Hailin Jiang, Wenming Yang, Wenming Yang, Wenming Yang, Han Wang, Han Wang, Meixia Wang, Meixia Wang, Xiang Li, Peng Huang, Shuzhen Fang, Wenjie Hao, Yue Yang, Furong Zhao, Wei He

“…Most practicing neurologists encounter only one or two cases of APS-2 combined with anti-GAD65 antibody-associated SPS in their careers, resulting in underdiagnosis and undertreatment, leading to severe disability and suffering. This case report describes a young male who initially exhibited hair loss, vitiligo, and previously unreported eosinophilia. …”
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Design and Evaluation of a Voice-Controlled Elevator System to Improve the Safety and Accessibility by Ander Gonzalez Docasal, Jon Alonso, Jon Olaizola, Mikel Mendicute, Maria Patricia Franco, Arantza Del Pozo, Daniel Aguinaga, Aitor Alvarez, Eduardo Lleida

“…This work introduces the design and assessment of a voice-controlled elevator system aimed at facilitating touchless interaction between users and hardware, thereby minimizing contact and improving accessibility for individuals with disabilities. The research distinguishes three distinct deployment scenarios—on cloud, on edge, and embedded—with the ultimate goal of integrating the entire system into a low-resource environment on a custom carrier board. …”
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Automatic Segmentation of Ischemic Stroke Lesions in CT Perfusion Maps Using Deep Learning Networks by Lida Zare Lahijan, Saeed Meshgini, Reza Afrouzian

“…Stroke is the third leading cause of death and the largest cause of acquired disability worldwide. Classification of stroke lesions is vital in recovery, diagnosis, outcome assessment, and treatment planning. …”
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