Using the Oxford Foot Model to determine the association between objective measures of foot function and results of the AOFAS Ankle-Hindfoot Scale and the Foot Function Index: a pr... by Frank Krummenauer, Tanja Kostuj, Felix Stief, Kirsten Anna Hartmann, Katharina Schaper, Mohammad Arabmotlagh, Mike H Baums, Andrea Meurer, Sebastian Lieske

“…An analysis of correlations with CIs between the FFI-D and the AOFAS-AHS items and the gait parameters was performed by means of the Jonckheere-Terpstra test; furthermore, exploratory factor analysis was applied to identify common information structures and thereby redundancy in the FFI-D and the AOFAS-AHS items.Results Objective findings for hindfoot disorders, namely a reduced ROM, in the ankle and subtalar joints, respectively, as well as reduced ankle power generation during push-off, showed a better correlation with the AOFAS-AHS total score—as well as AOFAS-AHS items representing ROM in the ankle, subtalar joints and gait function—compared with the FFI-D score.Factor analysis, however, could not identify FFI-D items consistently related to these three indicator parameters (pain, disability and function) found in the AOFAS-AHS. Furthermore, factor analysis did not support stratification of the FFI-D into two subscales.Conclusions The AOFAS-AHS showed a good agreement with objective gait parameters and is therefore better suited to evaluate disability and functional limitations of patients suffering from foot and ankle pathologies compared with the FFI-D.…”
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Impact of ultrasound-guided percutaneous flexor retinaculum fenestration on outcome of hydrostatic dissection of median nerve in patient with carpal tunnel syndrome by Ahmed M. Zidan, Hytham Mohamed Nafady, Mohamed Abdelrahman Alkenawy, Mohammad Abol Wafa Ahmad, Ahmed Mohamed Eldeeb, Mohamed Talaat Mohamed, Mahmoud Mohamed Aboumandour Fouda, Hasan A. Soltan, Nehal Elsayed Shabaan, Ahmed B. M. Mehany, Yasser Fouad Ghoraba

“…Methods This randomized clinical research included a total of 54 individuals with CTS separated into two groups; group (A) included patients with hydrostatic dissection with adjuvant fenestration of transverse carpal ligament (n = 27), while group (B) involved patients with hydrostatic dissection alone (n = 27). Pain and disability through the visual analog scale (VAS), symptom severity (SS) score, modified Boston Carpal Tunnel Questionnaire (BCTQ), and functional disability (FD) score before injection and 3 months post-injection were assessed. …”
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Acute Care Practice in the United States: The Roles of Occupational Therapy and Physical Therapy in Early Rehabilitation by Suzanne E. Holm, Kelly Nelson, Angela Patterson

“…With ER, the specific OT and PT rehabilitative interventions minimize the risk for negative health conditions, impairments, and disability while simultaneously promoting functional recovery. …”
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Progress in the application of motor imagery therapy in upper limb motor function rehabilitation of stroke patients with hemiplegia by Shuying Shen, Tianchen Chu, Jing Wang, Hangyu Zhao, Jinli Tang, Linya Xu, Wei Ni, Liping Tan, Yu Chen

“…Stroke is the leading cause of disability in Chinese adults. Upper limb motor dysfunction is a common manifestation of neurological dysfunction after stroke and can exert significant effects on a patient’s daily living ability and quality-of-life. …”
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Deep Brain Stimulation in Parkinson’s Disease: New and Emerging Targets for Refractory Motor and Nonmotor Symptoms by Dustin Anderson, Grayson Beecher, Fang Ba

“…Deep brain stimulation (DBS) has become a crucial player in PD treatment, particularly for patients who have disabling motor complications from medical treatment. …”
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Antioxidant and Anti-Inflammatory Properties of Melatonin in Secondary Traumatic Brain Injury by Mariusz Sieminski, Michalina Reimus, Maria Kałas, Ewelina Stępniewska

“…As TBI is a significant cause of mortality and chronic disability, with high social costs all over the world, any form of therapy that may mitigate trauma-evoked brain damage is desirable. …”
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Glittering Hope: Evaluating the bicycles for educational empowerment (BEEP) programme as panacea to inclusive education in Zimbabwe by Taruvinga Muzingili, Raymond Taruvinga

“…However, challenges included inadequate maintenance strategies, safety concerns, and a lack of a disability-sensitive approach. The study concludes that BEEP positively influences educational outcomes but urgently requires an integrated model for sustainability. …”
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A CD26+ tendon stem progenitor cell population contributes to tendon repair and heterotopic ossification by Siwen Chen, Yingxin Lin, Hao Yang, Zihao Li, Sifang Li, Dongying Chen, Wenjun Hao, Shuai Zhang, Hua Chao, Jingyu Zhang, Jianru Wang, Zemin Li, Xiang Li, Zhongping Zhan, Hui Liu

“…Abstract Inadequate tendon healing and heterotopic bone formation result in substantial pain and disability, yet the specific cells responsible for tendon healing remain uncertain. …”
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Biological treatment options for eosinophilic asthma, with consideration of markers of eosinophilic inflammation as predictors of treatment efficacy by Aleksandra Niemiec, Olga Branicka, Barbara Rymarczyk, Radosław Gawlik

“…Asthma, particularly uncontrolled asthma, not only reduces the quality of life but is also a major cause of disability for employment. The current pharmacologic strategy to therapy consists mostly of inhaled glucocorticoids and β-agonists, as well as leukotriene antagonists, long-acting muscarinic antagonists, and oral corticosteroids. …”
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Developments in Diagnosis and Antileishmanial Drugs by Prachi Bhargava, Rajni Singh

“…Leishmaniasis ranks the third in disease burden in disability-adjusted life years caused by neglected tropical diseases and is the second cause of parasite-related deaths after malaria; but for a variety of reasons, it is not receiving the attention that would be justified seeing its importance. …”
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Spinous Process Osteochondroma as a Rare Cause of Lumbar Pain by Bárbara Rosa, Pedro Campos, André Barros, Samir Karmali, Esperança Ussene, Carlos Durão, João Alves da Silva, Nuno Coutinho

“…A 70-year-old male presented with progressive and disabling lower lumbar pain. Tenderness over the central and left paraspinal area of the lower lumbar region and a palpable mass were evident. …”
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Assessing Children's Anxiety Using the Modified Short State-Trait Anxiety Inventory and Talking Mats: A Pilot Study by Stefan Nilsson, Margret Buchholz, Gunilla Thunberg

“…Children, with or without disability, are helped when pictures are used to support communication. …”
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Circulating LncRNA Is Potentially Up-regulated in Coronary Artery Disease by Niloofar Avazpour, Mohammadreza Hajjari, Saeed Yazdankhah, Azita Sahni, Ali Mohammad Foroughmand

“…Coronary artery disease (CAD) is one of the leading causes of death and disability all around the world. Recent studies have revealed that aberrantly regulated long non-coding RNA (lncRNA) as one of the main classes of cellular transcript plays a key regulatory role in transcriptional and epigenetic pathways. …”
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Arsenic Contamination of Groundwater: A Review of Sources, Prevalence, Health Risks, and Strategies for Mitigation by Shiv Shankar, Uma Shanker, Shikha

“…Excessive and prolonged exposure of inorganic As with drinking water is causing arsenicosis, a deteriorating and disabling disease characterized by skin lesions and pigmentation of the skin, patches on palm of the hands and soles of the feet. …”
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Emerging Roles of BAI Adhesion-GPCRs in Synapse Development and Plasticity by Joseph G. Duman, Yen-Kuei Tu, Kimberley F. Tolias

“…Abnormalities in synapse and spine formation and plasticity are associated with a broad range of brain disorders, including intellectual disabilities, autism spectrum disorders (ASD), and schizophrenia. …”
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Beneficial effects of baicalein on a model of allergic rhinitis by Liu Tao, Xu Jing, Wu Yungang, Li Xiaoxia, Ding Detao, Ma Dengdian, Yao Mengwei, Wei Wenzhong, Zhang Wei, Wang Shaohua, Yao Jing, Li Xiaoyu

“…Allergic rhinitis (AR) is a common disease that causes severe inflammation and even disabilities. Previous studies have reported baicalein to have an anti-inflammatory effect. …”
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miRNA in blood-brain barrier repair: role of extracellular vesicles in stroke recovery by Vojtech Sprincl, Vojtech Sprincl, Nataliya Romanyuk

“…Ischemic stroke is a leading cause of mortality and long-term disability globally. One of its aspects is the breakdown of the blood-brain barrier (BBB). …”
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Macrophage Polarization in the Osteoarthritis Pathogenesis and Treatment by Xiongfei Zou, Hongjun Xu, Wenwei Qian

“…ABSTRACT Osteoarthritis (OA) is a prevalent degenerative disorder that severely impacts quality of life due to pain and disability. Although the pathophysiology of OA remains incompletely understood, recent research highlights the role of synovial inflammation in OA onset and progression, driven primarily by inflammatory infiltrates, especially macrophages, in the synovium. …”
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Controversy About Management of Osteoarthritis with Disease-modifying Anti-rheumatic Drugs by CUI Hanshu, LIU Bin

“…It leads to pain, stiffness, deformation and even disability in the patients, and increases the risk of comorbidities. …”
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Insights into Cancer-Associated Thrombosis Leading Towards Ischemic Stroke by Surajit Hansda, Hiranmoy Das

“…Stroke leads to significant disability in most patients, whereas cancer elevates the occurrence of stroke. …”
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