Intramedullary Fixation for Metacarpal Fractures: A Multi-Institutional Prospective Outcomes Study by Michael B. Gehring, MD, Brandon Wolfe, BA, Riley Kahan, BS, Stephanie D. Malliaris, MD, Kia M. Washington, MD, Matthew D. Folchert, MD, Kyros Ipaktchi, MD, Mark A. Greyson, MD, Alexander Lauder, MD, Matthew L. Iorio, MD

“…Radiographic healing was assessed at each postoperative visit and patient-reported outcomes included pain scores, QuickDASH (Disabilities of the Arm, Shoulder, and Hand), and Short Form Survey scores. …”
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Prevalence of psoriatic arthritis in Italy: insights from the multicentric MAPSI study by Teodora Serban, Giuseppina Tramontano, Monica Pendolino, Dario Roccatello, Oscar Massimiliano Epis, Florienzo Iannone, Ilenia De Andres, Marta Favero, Nicoletta Romeo, Guido Rovera, Leonardo Santo, Enrico Tirri, Alberto Bergamini, Roberta Foti, Carlotta Schenone, Gerolamo Bianchi

“…Early diagnosis is crucial to prevent long-term disability and prevent comorbidities. While classification criteria for PsA are widely accepted, the lack of specific diagnostic criteria may delay diagnosis, with many patients experiencing delays of over a year before receiving an accurate diagnosis. …”
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Disease burden of biliary tract cancer in 204 countries and territories, 1990–2021: A comprehensive demographic analysis of the Global Burden of Disease Study 2021 by Xuheng Sun, Jiangmei Liu, Wei Zhang, Yijun Wang, Yan Jiang, Lijun Wang, Yixin Zou, Yuxuan Xiao, Yongbing Xiang, Maolan Li, Maigeng Zhou, Yingbin Liu, Sihan Zhou, Xiuyuan Hao

“…The number of incident cases, deaths, and disability-adjusted life-years (DALYs) tended to increase and peaked at 216,770 (95% uncertainty interval [UI]: 181,890–245,240), 171,960 (95% UI: 142,350–194,240), and 3,732,100 (95% UI: 3,102,900–4,317,000) person-years, respectively, in 2021. …”
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Protein kinases MpkA and SepH transduce crosstalk between CWI and SIN pathways to activate protective hyphal septation under echinocandin cell wall stress by Alexander G. Doan, Jessica E. Schafer, Casey M. Douglas, Matthew S. Quintanilla, Meredith E. Morse, Harley Edwards, Walker D. Huso, Kelsey J. Gray, JungHun Lee, Joshua K. Dayie, Steven D. Harris, Mark R. Marten

“…We also describe, for the first time, the signaling pathway used to deploy the hyperseptation response. By disabling this pathway, we were able to render mycelia susceptible to echinocandin stress. …”
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Occupational outcomes of people with multiple sclerosis: a scoping review by Guglielmo Dini, Alfredo Montecucco, Nicoletta Debarbieri, Paolo Durando, Giuliana Buresti, Benedetta Persechino, Matilde Inglese, Bruno Kusznir Vitturi, Alborz Rahmani, Elvira Sbragia, Paolo Bandiera, Michela Ponzio, Mario Alberto Battaglia, Tommaso Manacorda

“…Concerning the occupational outcomes, studies mostly addressed unemployment (311, 77.2%), early retirement (120, 29.8%), disability pension (117, 29.0%), sick leave (77, 19.1%), the indirect cost of MS (74, 18.4%) and work characteristics (57, 14.1%). …”
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The current state of knowledge on the role of NKG2D ligands in multiple sclerosis and other autoimmune diseases by Aleksandra Pogoda-Wesołowska, Nina Sługocka, Agnieszka Synowiec, Klaudia Brodaczewska, Marcin Mejer-Zahorowski, Maciej Ziękiewicz, Wojciech Szypowski, Piotr Szymański, Adam Stępień

“…It is the most common nontraumatic and disabling disease affecting young adults. The incidence and prevalence of MS have been increasing. …”
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How can Blood Flow Restriction Exercise be Utilised for the Management of Persistent Pain Following Complex Injuries in Military Personnel? A Narrative Review by Luke Gray, Peter Ladlow, Russell J Coppack, Robyn P Cassidy, Lynn Kelly, Sarah Lewis, Nick Caplan, Robert Barker-Davies, Alexander N Bennett, Luke Hughes

“…., complex regional pain syndrome, non-freezing cold injury), leading to extensive disability and reduced physical function. Conventional resistance training is commonly contraindicated in load compromised and/or persistent pain populations, compromising rehabilitation progression and potentially leading to extensive pharmacological intervention, invasive procedures, and reduced occupational status. …”
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Incidence and Risk Factors of Lumbosacral Complications Following Long‐Segment Spinal Fusion in Adult Degenerative Scoliosis by Tinghua Jiang, Xinuo Zhang, Qingjun Su, Xianglong Meng, Aixing Pan, Hanwen Zhang, Yong Hai

“…A total of 54 pairs of patients were matched and grouped, and the complication group had higher Oswestry Disability Index (ODI) and visual analog scale (VAS) scores at the last follow‐up. …”
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Effectiveness and safety of percutaneous endoscopic debridement and drainage for spinal infections: a systematic review and meta-analysis by Guozhong Zhou, Xiaorong Liu, Zhi Liang, Xuesong Chen, Chao Song

“…Similarly, the c-reactive protein (CRP), visual analogue scale, and oswestry disability index scores significantly reduced postoperatively. …”
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Association of Vitamin D Levels and Clothing Pattern in Women of Reproductive Age Group Having Chronic Back Pain by Shubham Saraswat, Anuj Rastogi, Farid Mohammad, Rachhanaa Pawaskar

“…Background: Chronic low back pain has been one of the most common musculoskeletal problems from the public health perspective owing to its high impact on disability and loss of productive years. The usefulness of Vitamin D in musculoskeletal health is widely acknowledged. …”
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Neutrophil-to-lymphocyte, platelet-to-lymphocyte ratios and systemic immune-inflammation index in patients with post-traumatic stress disorder by Gözde Yontar, Elif Aktan Mutlu

“…Exclusion criteria were as follows: presence of PTSD symptoms shorter than one month, presence of psychiatric comorbidity, being diagnosed with psychotic disorder, bipolar disorder, autism spectrum disorder, presence of mental retardation, being under psychotropic drug treatment, presence of a neurological disease that may cause serious disability (epilepsy, cerebrovascular disease), migraine, presence of organic brain damage, smoking, alcohol and substance use disorder, presence of a chronic disease such as diabetes mellitus, hypertension, hyperlipidemia, chronic lung diseases, being in pregnancy and breastfeeding, presence of heart disease were determined as exclusion criteria. …”
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Forecasting stroke and stroke-driven dementia in a rapidly ageing population: a model-based analysis of alternative projection scenarios for Ireland by Anne Hickey, Eithne Sexton, Frances Horgan, Kathleen E Bennett, Ronan Collins, Martin O'Flaherty, Suzanne Timmons, Chris Macey, David J. Williams

“…We used multiple data sources, including systematic review and observational evidence.Interventions Not applicable.Primary and secondary outcome measures We projected the incidence and prevalence of stroke (International Classification of Disease (ICD) codes I60–I61, I63–I64), poststroke dementia (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) criteria) and poststroke disability (modified Rankin Scale 3–5).Results The stable scenario indicated a projected 85 834 stroke survivors in 2046 (95% uncertainty interval (UI)=82 366–89 655), an increase of 45.7% from 2022. …”
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Burden of esophageal cancer in global, regional and national regions from 1990 to 2021 and its projection until 2050: results from the GBD study 2021 by Chengcheng Zhang, Linzhi Chen, Yuqi Xiu, Hongling Zhang, Yuejuan Zhang, Wenjuan Ying

“…This study aimed to systematically assess the global burden and trends of esophageal cancer across diverse populations.MethodsData on the burden of EC were collected from the Global Burden of Disease (GBD) 2021 study, including estimates of incidence, mortality, and disability-adjusted life years (DALYs), as well as risk factors, spanning 204 countries and territories. …”
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The burden of chronic kidney disease attributable to high sodium intake: a longitudinal study in 1990–2019 in China by Yongyao Shen, Liying Jiang, Liying Jiang, Jin Yu, Bo Chen, Aidong Liu, Yongjin Guo, Yongjin Guo

“…CKD burden [deaths and disability-adjusted life years (DALYs)] was quantified according to population group (age, gender) and regions categories (province, SDI). …”
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Influence of Interactive Scalp Acupuncture Combined with Upper Limb Exoskeleton Robot on Upper Limb Function in Stroke Patients by WANG Zihao, HU Chuan, ZHANG Haiquan, WANG Xin

“…Pre- and post-treatment assessments of upper limb motor function before and after treatment were performed using the Fugl-meyer upper extremity motor function assessment scale (FMA-UE) within the domain of body functions and structures according to the Iinternational Cassification of Functioning, Disability and Health Framework (ICF). In addition, within the ICF activity domain, the Wolf motor function test (WMFT) was utilized to assess patients' abilities to perform functional tasks with their upper limbs. …”
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Functional performance of patients with stroke during inpatient rehabilitation: a cross-sectional study of home and access visits by Melissa J. Krauss, Emily Somerville, Callista Poiter, Rebecca M. Bollinger, Brianna M. Holden, Gabrielle Blenden, Danielle Kretzer, Susan L. Stark

“…International Classification of Functioning, Disability, and Health (ICF) qualifier scores were compared between participants’ home/access visits and IRF discharge. …”
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Comparison of Accuracy in Expert Clinical Examination versus Magnetic Resonance Imaging and Arthroscopic Exam in Diagnosis of Meniscal Tear by Seyed Ali Hashemi, Mohammad Reza Ranjbar, Mohammad Tahami, Reza Shahriarirad, Amirhossein Erfani

“…Torn menisci or ligamentous structures within the knee cause significant pain and disability and thus require expeditious management. …”
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Reducing medical cannabis use risk among Veterans: A descriptive study by Laura M. Harris-Lane, Mitchell Sheehy, Courtney A. Loveless, Joshua A. Rash, David P. Storey, Gregory K. Tippin, Vikas Parihar, Nick Harris

“…Results Veterans who currently use cannabis were more likely to be unemployed (z = 3.62, p < .01), released as a Non-Commissioned Officer (z = -3.83, p < .01), and unable to work due a disability (z = -3.43, p < .01) than Veterans who do not currently use. …”
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Learning Curve of Uniportal Compared With Biportal Endoscopic Techniques for the Treatment of Lumbar Disc Herniation by Yuquan Liu, Xiang Li, Haining Tan, Xinyi Hao, Bin Zhu, Yong Yang, Lingjia Yu

“…Secondary outcomes assessing endoscopic prowess include surgical outcomes, such as fluoroscopy usage times, postoperative hospital stays, the incidence of complications, and clinical outcomes, including visual analog scale (VAS) scores for back and leg pain, Oswestry disability index (ODI) score and modified MacNab criteria. …”
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Impact of diagnosis-related group payment on medical expenditure and treatment efficiency on people with drug-resistant tuberculosis: a quasi-experimental study design by Yingbei Xiong, Yifan Yao, Yuehua Li, Shanquan Chen, Yunfei Li, Kunhe Lin, Li Xiang

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