Low-density Lipoproteins and Degrees of Cardiovascular Risk in Adults over 40 Years of Age: Case-control Study by Abel Pérez Pavón, Francisco Sánchez Hernández, Karla Doriam Gámez Ávalos, Donovan Casas Patiño, Alejandra Rodríguez Torres

“…<strong>Foundation:</strong> cardiovascular diseases are the main cause of death and disability in the world. Its incidence and prevalence has increased over the last decade and accounts for a third of all deaths. …”
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Association of vitamin D receptor gene polymorphisms with rheumatoid arthritis by Noelia Marquez Pete, Cristina Perez Ramirez, Maria del Mar Maldonado Montoro, Fernando Martinez Martinez, Fernando Fernández-Llimos, Antonio Sánchez Pozo, María del Carmen Ramirez Tortosa, Alberto Jiménez Morales

“…Introduction Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease of unknown etiology which causes progressive deterioration of the joints, leading to severe pain and functional disability. Vitamin D and its receptor (VDR) play a significant part in the onset of autoimmune diseases such as RA. …”
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Successful open defecation-free intervention in low- and middle-income countries: a qualitative synthesis systematic review protocol by Vera Yulyani, Iswanto Iswanto, Daniel Daniel, Fitrina Mahardani Kusumaningrum, Fatwa Sari Tetra Dewi

“…Research examining sanitation interventions in schools, shelters, disability communities and virtual communities was excluded, as the review focused exclusively on community-based interventions. …”
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Risk of depression in glaucoma patients with vision impairment: A nationwide cohort study by Sheng-Min Wang, Younhea Jung, Kyungdo Han, Kyoung Ohn, Hae-young Lopilly Park, Chan Kee Park, Jung Il Moon

“…Methods: We conducted a nationwide, population-based cohort study using data from the Korean National Health Information Database and National Disability Registry. We assessed baseline characteristics such as age, sex, income level, lifestyle factors, anthropometric data, lab results, and Charlson Comorbidity Index scores through diagnostic codes and health screening data. …”
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Impact of Sex on the Nonmotor Symptoms and the Health-Related Quality of Life in Parkinson’s Disease by Márton Kovács, Attila Makkos, Zsuzsanna Aschermann, József Janszky, Sámuel Komoly, Rita Weintraut, Kázmér Karádi, Norbert Kovács

“…Although females received significantly lower dosage of levodopa, they had significantly more disabling dyskinesia and worse postural instability. …”
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Milestones and Timescale of Poststroke Recovery: A Cohort Study by Marianna Loi, Alberto Zaliani, Marta Abbamonte, Elena P. Ferrari, Roberto Maestri, Luigi Trojano, Pietro Balbi

“…As many stroke survivors chronically show severe disability, increase in economic, social, and medical burden could be expected in the future. …”
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Modelling the potential clinical and economic impact of universal antenatal hepatitis C (HCV) screening and providing treatment for pregnant women with HCV and their infants in Egy... by Giuseppe Indolfi, Diana M Gibb, Aya Mostafa, Sarah Pett, Yazdan Yazdanpanah, Sylvie Deuffic-Burban, Anthony E Ades, Karen Scott, Ali Judd, Nadia Hachicha-Maalej, Clotilde Lepers, Intira Jeannie Collins, Manal H El Sayed

“…Discounted lifetime cost, life expectancy (LE) and disability-adjusted life-years (DALYs) were calculated separately for women and their infants, and then combined.Results Current practice led to the highest cost (US$314.0), the lowest LE (46.3348 years) and the highest DALYs (0.0512 years) per mother–child pair. …”
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Novel nonsense mutation in gene CHRNA2 identified by whole-genome sequencing in infant with epilepsy disorder: A case report by Sultan Makhmetov, Kamila Temirkhanova, Saule Rakhimova, Nazerke Satvaldina, Ruslan Kalendar, Ulan Kozhamkulov, Aidos Bolatov, Mirgul Bayanova, Assiya Bazenova, Lyazzat Nazarova, Ainur Akilzhanova, Ulykbek Kairov

“…It impacts people of all genders and ages, but evidence suggests a higher incidence rate in children and the elderly.Given that childhood epilepsy has the risk of causing developmental epileptic encephalopathy, which is associated with intellectual, behavioral, and/or motor disabilities, proper assessment of children with new-onset epilepsy at an early stage is essential to prevent threats affecting neurodevelopmental processes. …”
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Trends and future predictions of chronic kidney disease due to diabetes mellitus type 2 attributable to dietary risks: insights based on GBD 2021 data by Ming Xu, Ming Xu, Hongxia Wei, Hongxia Wei, Dongqing Lv, Dongqing Lv, Yanhong Wei, Yanhong Wei, Ziang Liu, Ziang Liu, Yi Zhang, Yi Zhang, Yunfeng Liu, Yunfeng Liu, Yunfeng Liu

“…This study examines the influence of dietary risk factors across various populations and socioeconomic groups.MethodsUtilizing the 2021 GBD data, we analyzed age-standardized CKD-T2DM metrics—including mortality, disability-adjusted life years (DALY), and age-standardized rates (ASR)—stratified by age, gender, and region. …”
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Protocol for a living systematic review for the management of concussion in adults by Mark Bayley, Diana Velikonja, Shawn Marshall, Alexander Lithopoulos, Dorothyann Curran, Lisa Fischer, Christopher Knee, Julia Lauzon, Margaret Nevison

“…Introduction Concussion/mild traumatic brain injury (mTBI) often presents initially with disabling symptoms that resolve, but for an unfortunate minority some of these symptoms may become prolonged. …”
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Follicular Helper CD4+ T Cells, Follicular Regulatory CD4+ T Cells, and Inducible Costimulator and Their Roles in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis by Xue Zhang, Ruli Ge, Hongliang Chen, Maxwell Ahiafor, Bin Liu, Jinbo Chen, Xueli Fan

“…Multiple sclerosis (MS) is a severe autoimmune disease that affects the central nervous system and results in disability, mediated by autoreactive T cells with evolving evidence of a remarkable contribution from humoral responses. …”
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Characteristics and Outcomes of Younger Adults with Embolic Stroke of Undetermined Source (ESUS): A Retrospective Study by Ali M. Al Khathaami, Bayan Al Bdah, Abdulmjeed Alnosair, Abdulkarim Alturki, Rayan Alrebdi, Shorug Alwayili, Sulaiman Alhamzah, Fahad A. M. AlKhathaami, Nasser Alotaibi

“…Although younger adults with ESUS had fewer risk factors, there were no significant differences in neurologic disability or mortality at discharge, stroke severity, or median length of stay.…”
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The multiple uses of artificial intelligence in exercise programs: a narrative review by Alberto Canzone, Alberto Canzone, Giacomo Belmonte, Antonino Patti, Domenico Savio Salvatore Vicari, Domenico Savio Salvatore Vicari, Fabio Rapisarda, Valerio Giustino, Patrik Drid, Antonino Bianco

“…The findings suggest that artificial intelligence holds promise in promoting physical activity across diverse populations, including children, adolescents, adults, older adult, and individuals with disabilities.ConclusionOur research found that artificial intelligence, machine learning and deep learning techniques were used: (a) as part of applications to generate automatic messages and be able to communicate with users; (b) as a predictive approach and for gesture and posture recognition; (c) as a control system; (d) as data collector; and (e) as a guided trainer.…”
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OPTIMIZATION OF CONCENTRATION AND SOAKING TIME OF HARRIS HEMATOXYLIN IN DNA BAND EXAMINATION USING ELECTROPHORESIS by Siti Nuristiqomah Fajri, Asep Iin Nur Indra, Fusvita Merdekawati, Acep Tantan H.

“…The commonly used dye Ethidium bromide (EtBr) is considered hazardous due to its potential to cause mutations, cancer, and congenital disabilities. Various alternative dyes have been reported, one of which is hematoxylin. …”
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Rehabilitation nursing for motor functional recovery of acute ischaemic stroke: study protocol for a randomised controlled trial by Yuanyuan Chen, Mei Li, Jianmiao Wang, Yuping Zhang, Jingfen Jin

“…Introduction Stroke is the second-leading cause of death and disability in the world, and patients with stroke often suffer from functional impairments and need rehabilitation. …”
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Advances in Serological Diagnosis of Neurocysticercosis in Korea by Chun-Seob Ahn, Jeong-Geun Kim, Sun Huh, Insug Kang, Yoon Kong

“…Cysticercosis, a parasitic disease caused by Taenia solium metacestode (TsM), has a major global public health impact in terms of disability-adjusted life years. The parasite preferentially infects subcutaneous tissue, but may invade the central nervous system, resulting in neurocysticercosis (NC). …”
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Changing the trajectories of mental health difficulties in Norfolk and Suffolk: a research-priority-setting project with patients, the public, clinicians, policymakers and other st... by Caitlin Notley, Jayati Das-Munshi, Craig Morgan, Kristy Sanderson, Sherifat Oduola, Zarnie Khadjesari, Helen Parretti, Niall Broomfield, Amy Zile, Sol Morrissey, Joni Holmes

“…Introduction Mental health problems are the most significant cause of disability and have high annual economic costs; hence, they are a priority for the government, service providers and policymakers. …”
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Systematic analysis of co-expression network and gene expression profile of differentially expressed lncRNA-mRNA one week after spinal cord injury by Yi Kang, Yijie Song, Zhongju Shi, Qiang Li, Yigang Lv, Mengfan Hou, Cui Ding, Jing Xie, Yongfu Lou, Chi Zhang, Huan Jian, Xueying Li, Hengxing Zhou, Shiqing Feng

“…Abbreviations: SCI: spinal cord injury; CNS: central nervous system; YLDs: years of life lived with disability; lncRNAs: long noncoding RNAs; mRNAs: messenger RNAs; DE: differentially expressed; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; GSEA: gene set enrichment analysis; RIN: Renewable Identification Number; PCA: principal component analysis; PPI: protein–protein interaction; MF, molecular function; BP: biological process; CC: cellular component; MCODE: molecular complex detection…”
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A Rule-Based Parser in Comparison with Statistical Neuronal Approaches in Terms of Grammar Competence by Simon M. Strübbe, Alexander T. D. Grünwald, Irina Sidorenko, Renée Lampe

“…The “Easy Language” standard was created to help individuals with cognitive disabilities understand texts more easily. Typically, text simplification is performed by language experts and is available for limited materials. …”
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Prescription of Strong Opioids in Chronic Non-Cancer Pain in the Province of Valladolid (Spain) by Rodrigo Enríquez de Salamanca Gambara, Ana María Sierra Santos, Ana María Ruiz San Pedro, Federico Montero Cuadrado, Irene Muñoz León, Miguel Ángel Castro Villamor, Alicia Córdoba Romero, Ana María Del Olmo Tornero, Lucía Pérez Pérez, León Morales-Quezada

“…<b>Background:</b> Chronic non-cancer pain (CNCP) is one of the leading causes of disability. The use of strong opioids (SOs) in the management of CNCP is increasing, although evidence supporting their use remains limited. …”
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