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  1. 2461

    Diagnosing skin neglected tropical diseases with the aid of digital health tools: A scoping review. by Ewelina Julia Barnowska, Anil Fastenau, Srilekha Penna, Ann-Kristin Bonkass, Sophie Stuetzle, Ricky Janssen

    Published 2024-10-01
    “…Delays in diagnosis and detection of skin neglected tropical diseases (NTDs) pose obstacles to prompt treatment, which is crucial in preventing disability. Recent developments in digital health have given rise to approaches that could increase access to diagnosis in resource-poor areas affected by skin NTDs. …”
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  2. 2462
  3. 2463

    Clinical characteristics and immunotherapy response in paraneoplastic neurologic syndrome patients with increased number of high-risk antibodies by Gong Wang, Mao Chen, Fei Gao, Meng Guo, Maohua Li, Qian He, Jiaojin Jiang, Cheng Huang, Xiaoyan Chen, Rui Xu

    Published 2025-01-01
    “…After immunotherapy treatment, Expanded Disability Status Scale (EDSS) scores in PNS patients with 2 high-risk antibodies were higher than that in PNS patients with 1 high-risk antibody (4.8 ± 2.4 vs. 3.0 ± 2.4, p = 0.043). …”
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  4. 2464

    Clinical and Epidemiological Characterization of Patients with Rheumatoid Arthritis by Zoe Alina González Otero, Jorge Luis Egüez Mesa, Celestino Fusté Jiménez, Eugenio Alejandro Reyes Medina, José Alberto Borges López, Lázaro Hermes González Otero

    Published 2015-12-01
    “…<strong>Background:</strong> rheumatoid arthritis is a chronic systemic inflammatory disease, it has varied clinical manifestations and cause different degrees of discomfort and disability. <strong><br />Objective:</strong> to conduct a clinical and epidemiological characterization of all rheumatoid arthritis patients admitted to the clinical services of the Arnaldo Milián Castro Provincial University Hospital. …”
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  5. 2465

    Microglia and Immune cells interactions in multiple sclerosis cognitive impairment: a postmortem study by Catarina Barros, Ainhoa Alberro, Adelaide Fernandes

    Published 2024-12-01
    “…Abstract Multiple Sclerosis (MS), a neuroinflammatory disease of the central nervous system, is one of the commonest causes of non-traumatic disability among young adults. Impaired cognition arises as an impactful symptom affecting more than 50% of the patients and with substantial impact on social, economic, and individual wellbeing. …”
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  6. 2466

    Effectiveness of robot-assisted task-oriented training intervention for upper limb and daily living skills in stroke patients: A meta-analysis. by Chengzhu Jin, Yonghuan Chen, Yuanyuan Ma

    Published 2025-01-01
    “…<h4>Purpose</h4>Stroke is one of the leading causes of acquired disability in adults in high-income countries. This study aims to determine the intervention effects of robot-assisted task-oriented training on enhancing the upper limb function and daily living skills of stroke patients.…”
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  7. 2467

    Cortistatin-14 Exerts Neuroprotective Effect Against Microglial Activation, Blood-brain Barrier Disruption, and Cognitive Impairment in Sepsis-associated Encephalopathy by Qiang Wen, Qian Ding, Jinchao Wang, Yanhua Yin, Shangchen Xu, Yuanrong Ju, Hongsheng Ji, Bin Liu

    Published 2022-01-01
    “…Sepsis-associated encephalopathy (SAE) is a life-threatening deterioration of mental status in relation to long-term and disabling cognitive dysfunction that is common in intensive care units worldwide. …”
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  8. 2468

    Multi-omics approaches for understanding gene-environment interactions in noncommunicable diseases: techniques, translation, and equity issues by Robel Alemu, Nigussie T. Sharew, Yodit Y. Arsano, Muktar Ahmed, Fasil Tekola-Ayele, Tesfaye B. Mersha, Azmeraw T. Amare

    Published 2025-01-01
    “…Abstract Non-communicable diseases (NCDs) such as cardiovascular diseases, chronic respiratory diseases, cancers, diabetes, and mental health disorders pose a significant global health challenge, accounting for the majority of fatalities and disability-adjusted life years worldwide. These diseases arise from the complex interactions between genetic, behavioral, and environmental factors, necessitating a thorough understanding of these dynamics to identify effective diagnostic strategies and interventions. …”
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  9. 2469

    Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature. by Adriano Casulli, Stefania Pane, Franco Randi, Paola Scaramozzino, Andrea Carvelli, Carlo Efisio Marras, Andrea Carai, Azzurra Santoro, Federica Santolamazza, Francesca Tamarozzi, Lorenza Putignani

    Published 2023-09-01
    “…Cyst rupture was reported in 12.96% and recurrence of CCE after treatment in 9.61% of cases. Permanent disability was reported in 7.86% of cases, while death occurred in 6.21%. …”
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  10. 2470
  11. 2471

    The global burden of otitis media in 204 countries and territories from 1992 to 2021: a systematic analysis for the Global Burden of Disease study 2021 by Guan-Jiang Huang, Bao-Rui Lin, Pei-Shan Li, Na Tang, Zhi-Jun Fan, Biao-Qing Lu

    Published 2025-01-01
    “…ObjectivesThis study aims to analyze the global burden of otitis media and predict future trends using data from the Global Burden of Disease 2021 (GBD 2021).Study designA cross-sectional analysis of GBD 2021 results was conducted.MethodsAge-standardized incidence rates (ASIR), age-standardized prevalence rates (ASPR), and age-standardized disability-adjusted life years (DALYs) rates (ASDR) were calculated. …”
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  12. 2472

    Use of ascorbic acid (vitamin C) and alpha tocopherol (vitamin E) as adjuvants in the treatment of neuropathic pain by Fernando Antonio Silva de Azevedo-Filho, Yasmim Machado Chaves de Castro, Marcos Pinho Cerqueira, Thiago Arruda Rodrigues, Yussef Ali-Abdouni, Patrícia Maria de Moraes Barros Fucs

    Published 2025-01-01
    “…At the initial assessment, the patients answered the Quick Disabilities of the Arm, Shoulder and Hand (Quick-DASH) to assess upper limb functionality; quality of life was described using the World Health Organization Quality of Life-Bref (WHOQOL-bref) and pain assessment was measured using the visual analogue scale (VAS). …”
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  13. 2473

    Serum Sclerostin as a Possible Biomarker in Ankylosing Spondylitis: A Case-Control Study by Fabio Massimo Perrotta, Fulvia Ceccarelli, Cristiana Barbati, Tania Colasanti, Antonia De Socio, Silvia Scriffignano, Cristiano Alessandri, Ennio Lubrano

    Published 2018-01-01
    “…However, no significant correlations were found between serum sclerostin levels and radiographic damage, assessed by mSASSS, and between serum sclerostin levels and clinical indices of activity and disability or with laboratory parameters. Sclerostin levels did not show significant changes after 4 months of anti-TNF therapy. …”
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  14. 2474

    Protocol for a prospective cohort study: Prevention of Transmissions by Effective Colonisation Tracking in Neonates (PROTECT-Neo) by Martin Wolkewitz, Roland Hentschel, Philipp Henneke, Daniel Jonas, Tim Götting, Sandra Reuter, Daniel Klotz, Simone Hock, Benjamin Blümel, Georg Häcker, Hajo Grundmann, Nico Mutters

    Published 2020-09-01
    “…Introduction Transmissions of opportunistic bacterial pathogens between neonates increase the risk of infections with negative repercussions, including higher mortality, morbidity and permanent disabilities. The probability of transmissions between patients is contingent on a set of intrinsic (patient-related) and extrinsic (ward-related) risk factors that are not clearly quantified. …”
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  15. 2475

    The Life Functioning Scale: A Measurement Tool Developed to Assess the Physical Functioning Abilities of Community-Dwelling Adults Aged 50 Years or Older by Yunhwan Lee, Eunsaem Kim, Jihye Yun, Jaewon Choi, Jinhee Kim, Chang Won Won, Miji Kim, Soongnang Jang, Kyungwon Oh, Jihee Kim

    Published 2024-12-01
    “…Results The newly developed Life Functioning (LF) scale assessed the dimensions of functional limitations, disabilities, and social activities. The scale satisfied a one-dimensionality assumption with good item fit and demonstrated criterion validity, construct validity, high internal consistency (Cronbach’s alpha=0.93), and test-retest reliability (intra-class correlation coefficient=0.84; 95% confidence interval, 0.76–0.89). …”
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  16. 2476

    Application of Anchoring Technique in Unilateral Percutaneous Vertebroplasty for Neurologically Intact Kümmell’s Disease by Rongqing Qin, Xing Zhang, Hongpeng Liu, Bing Zhou, Pin Zhou, Chuanliang Hu

    Published 2020-01-01
    “…Clinical efficacy was evaluated by back pain visual analogue scale (BP-VAS) score, Oswestry disability index (ODI) score, as well as the height of anterior border and the kyphotic angle of the involved vertebral body on a standing lateral radiograph. …”
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  17. 2477

    Tree shrew as a new animal model for musculoskeletal disorders and aging by Xiaocui Wei, Honghao Li, Jingyang Qiu, Jianlin Jiao, Xiongtian Guo, Gaosheng Yin, Ping Yang, Yi Han, Qiongzhi Zhao, Hao Zeng, Zhi Rao, Xuefei Gao, Kai Li, Pinglin Lai, Sheng Zhang, Chengliang Yang, Di Lu, Xiaochun Bai

    Published 2025-01-01
    “…Abstract Intervertebral disc degeneration (IDD), osteoarthritis (OA), and osteoporosis (OP) are common musculoskeletal disorders (MSDs) with similar age-related risk factors, representing the leading causes of disability. However, successful therapeutic development and translation have been hampered by the lack of clinically-relevant animal models. …”
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  18. 2478

    Identification of Potential Clusters of Signs and Symptoms to Prioritize Patients’ Eligibility for AADCd Screening by 3-OMD Testing: An Italian Delphi Consensus by Carlotta Spagnoli, Roberta Battini, Filippo Manti, Duccio Maria Cordelli, Andrea Pession, Melissa Bellini, Andrea Bordugo, Gaetano Cantalupo, Antonella Riva, Pasquale Striano, Marco Spada, Francesco Porta, Carlo Fusco

    Published 2024-01-01
    “…The following statements reached the highest priority: testing pediatric patients with hypotonia, developmental delay, movement disorders, and oculogyric crises; inclusion of 3-OMD dosing on DBS in neonatal screening programs; development of a clinical score to support patients’ selection for 3-OMD screening; among atypical phenotypes based on clinical characteristics of Italian patients: testing patients with intellectual disability and parkinsonism-dystonia. Discussion. Clusters of symptoms and signs can be used to prioritize testing with 3-OMD DBS. …”
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  19. 2479

    Evaluation of transcriptomic changes after photobiomodulation in spinal cord injury by Andrew R. Stevens, Mohammed Hadis, Hannah Alldrit, Michael R. Milward, Valentina Di Pietro, Deena M. A. Gendoo, Antonio Belli, William Palin, David J. Davies, Zubair Ahmed

    Published 2025-01-01
    “…Abstract Spinal cord injury (SCI) is a significant cause of lifelong disability, with no available disease-modifying treatments to promote neuroprotection and axon regeneration after injury. …”
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  20. 2480

    Effects of Different Taping Techniques in Individuals with Myofascial Pain Syndrome with a Trigger Point in the Trapezius Muscle: A Sham-controlled Randomized Study by Kubra KARDES, Pinar VAN DER VEER, Yunus Emre TUTUNEKEN, Hale Nur AYKAC, Esra ARSLAN, Aysenur AKSOY, Yasemin BURAN CIRAK

    Published 2024-03-01
    “…The visual analog scale was used to assess pain, cervical joint range of motion (ROM) with a universal goniometer, grip strength with a hand dynamometer, number of active trigger points by palpation, pressure-pain threshold with an algometer, quality of life with the Nottingham Health Profile and functional level with the Neck Disability index were evaluated before and after treatment. …”
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