Acupuncture as prophylaxis for chronic migraine: a protocol for a single-blinded, double-dummy randomised controlled trial by Claire Shuiqing Zhang, Bin Li, Lin Zeng, Lu Liu, Luo-peng Zhao, Kelun Wang, Jingxia Zhao, Linpeng Wang, Xianghong Jing

“…The primary outcome is the reduction of monthly headache days, and the secondary outcomes include the reduction of the number of days with acute headache medications, and changes of Migraine Disability Assessment, Migraine-Specific Quality of Life Questionnaire, Headache Impact Test, State-Trait Anxiety Inventory-trait, and Beck Depression Inventory-II scores from baseline to endpoints.Ethics and dissemination Ethical approval of this study was granted by the Research Ethical Committee of Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University (2017BL-045-01). …”
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Targeted Neuromodulation of Abnormal Interhemispheric Connectivity to Promote Neural Plasticity and Recovery of Arm Function after Stroke: A Randomized Crossover Clinical Trial Stu... by Michael R. Borich, Steven L. Wolf, Andrew Q. Tan, Jacqueline A. Palmer

“…Despite intensive rehabilitation efforts, most stroke survivors have persistent functional disability of the paretic arm and hand. These motor impairments may be due in part to maladaptive changes in structural and functional connections between brain regions. …”
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Autoinflammatory Bone Diseases by Fatih Haşlak, Nergis Akay, Ümit Gül, Aybüke Günalp, Elif Kılıç Könte, Sezgin Şahin, Özgür Kasapçopur

“…However, if not diagnosed and treated promptly, it can result in significant complications, including severe disability and mortality. Thus, it is imperative to maintain a high level of clinical awareness of these diseases. …”
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Efficacy and safety of interferon-alpha 1b injection into the intervertebral foramen with ultrasonic guidance in patients with postherpetic neuralgia: study protocol for a randomiz... by Hui-Min Hu, Hui-Min Hu, Wen-Hui Liu, Wen-Hui Liu, Chen Li, Chen Li, Qing Shi, Qing Shi, Chun-Hua Liu, Chun-Hua Liu, An-Xiang Liu, An-Xiang Liu, Yi-Fan Li, Yi Zhang, Peng Mao, Bi-Fa Fan

“…PurposePostherpetic neuralgia (PHN) is a type of refractory neuropathic pain that causes significant suffering, disability, economic loss, and medical burden. In this study, we aim to evaluate the efficacy and safety of interferon (IFN)-α1b injection into the intervertebral foramen of patients with PHN.Patients and methodsThis is a study protocol for a randomized, double-blind placebo-controlled multicenter clinical trial. …”
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Therapeutic Adherence in Patients with Arterial Hypertension by Liens Hernández Quintero, Diana Amelia Crespo Fernández, Liliet Trujillo Cruz, Liliana María Hernández Quintero, Marcia Azcuy Pérez

“…<strong>Background:</strong> arterial hypertension is presented worldwide as one of the main causes of death and disability. Lack of adherence to treatment is one of this disease great problems. …”
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Comparison of Manual, Automatic, and Voice Control in Wheelchair Navigation Simulation in Virtual Environments: Performance Evaluation of User and Motion Sickness by Enrique Antonio Pedroza-Santiago, José Emilio Quiroz-Ibarra, Erik René Bojorges-Valdez, Miguel Ángel Padilla-Castañeda

“…Mobility is essential for individuals with physical disabilities, and wheelchairs significantly enhance their quality of life. …”
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Social media activism and women's health: Endometriosis awareness and support by Hyunjin Seo, K. Macy Burkett, Moses Okocha, Huong Ha, Rim Chaif, Nazra Izhar, Michaella Barros Coelho, Blessing Jona, Azhar Iqbal

“…In addition, social media users widely incorporated three feminism themes: (i) bringing attention to invisible disability, (ii) solidarity and support among women, and (iii) advocacy and activism around women's health. …”
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The global, regional burden of pancreatic cancer and its attributable risk factors from 1990 to 2021 by Weidong Yu, Danyi Zhou, Fanhao Meng, Jinjing Wang, Bo Wang, Jianling Qiang, Lijun Shen, Maofeng Wang, Hezhi Fang

“…Methods The degree and change patterns of exposure as well as the attributable cancer burden, including incidence, mortality, disability-adjusted life years (DALYs), and prevalence in global and regional, by sex, age, year, for pancreatic cancer, with the data extracted from the Global Burden of Diseases Study (GBD) 2021. …”
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Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors by Lorena R. S. Almeida, Guilherme T. Valença, Nádja N. Negreiros, Elen B. Pinto, Jamary Oliveira-Filho

“…Falls can be considered a disabling feature in Parkinson’s disease. We aimed to identify risk factors for falling, testing simultaneously the ability of disease-specific and balance-related measures. …”
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Autoantibodies to NR2A Peptide of the Glutamate/NMDA Receptor in Patients with Seizure Disorders in Neuropsychiatric Systemic Lupus Erythematosus by Yan Yang, Chao Yuan, Shu-qun Shen, Xue-er Wang, Qing-hua Mei, Wen-qing Jiang, Qin Huang

“…Seizure disorders are one of the most disabling, life-threatening, and the least understood syndromes associated with neuropsychiatric SLE (NPSLE). …”
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Differential diagnosis of rheumatic manifestations of acromegaly. Case report by Margarita A. Perepelova, Larisa K. Dzeranova, Taras S. Panevin, Elena G. Przhiyalkovskaya, Ekaterina A. Pigarova, Ekaterina A. Troshina, Evgeniy G. Zotkin

“…Diagnosis of the disease in the early stages is often difficult and is established 5–10 years after the onset of symptoms, that leads to various complications and disability of patients. Often joint pain is the first manifestation of acromegaly. …”
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Automated Quantification of Neuropad Improves Its Diagnostic Ability in Patients with Diabetic Neuropathy by Georgios Ponirakis, Hassan Fadavi, Ioannis N. Petropoulos, Shazli Azmi, Maryam Ferdousi, Mohammad A. Dabbah, Ahmad Kheyami, Uazman Alam, Omar Asghar, Andrew Marshall, Mitra Tavakoli, Ahmed Al-Ahmar, Saad Javed, Maria Jeziorska, Rayaz A. Malik

“…The diagnostic performance of Neuropad was compared between the categorical and continuous (image-analysis (Sudometrics)) outputs to diagnose diabetic peripheral neuropathy (DPN). 110 subjects with type 1 and 2 diabetes underwent assessment with Neuropad, Neuropathy Disability Score (NDS), peroneal motor nerve conduction velocity (PMNCV), sural nerve action potential (SNAP), Deep Breathing-Heart Rate Variability (DB-HRV), intraepidermal nerve fibre density (IENFD), and corneal confocal microscopy (CCM). 46/110 patients had DPN according to the Toronto consensus. …”
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Central Precocious Puberty and Response to GnRHa Therapy in Children with Cerebral Palsy and Moderate to Severe Motor Impairment: Data from a Longitudinal, Case-Control, Multicentr... by Patrizia Bruzzi, Maria Francesca Messina, Alessandra Bartoli, Barbara Predieri, Laura Lucaccioni, Simona Filomena Madeo, Alberto Verrotti, Filippo De Luca, Lorenzo Iughetti

“…Children affected by neurodevelopmental disability could experience early pubertal changes at least 20 times more than the general population. …”
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Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder by Claudia Fuchs, Laura Gennaccaro, Stefania Trazzi, Stefano Bastianini, Simone Bettini, Viviana Lo Martire, Elisa Ren, Giorgio Medici, Giovanna Zoccoli, Roberto Rimondini, Elisabetta Ciani

“…CDKL5 disorder primarily affects girls and is characterized by early-onset epileptic seizures, gross motor impairment, intellectual disability, and autistic features. Although all CDKL5 female patients are heterozygous, the most valid disease-related model, the heterozygous female Cdkl5 knockout (Cdkl5 +/−) mouse, has been little characterized. …”
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Efficacy Comparison of Various Repair Techniques for Flexor Tendon Injuries: A Systematic Review and Meta-Analysis by Anak Agung Gde Duta Maha Putra, Made Bramantya Karna, Anak Agung Gde Yuda Asmara, Putu Feryawan Meregawa

“…Background: Flexor tendon injuries are potentially disabling, as flexor tendons are essential to hand function, playing a vital role in all types of grip, including power and fine pinch grips. …”
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Thoracolumbar spine fracture patterns, etiologies, and treatment modalities in Jordan by Ahmad Almigdad, Sattam Alazaydeh, Mohammad Bani Mustafa, Mu'men Alshawish, Anas Al Abdallat

“…Purpose Spine fractures are a significant cause of long-term disability and socioeconomic burden. The incidence of spine fractures tends to increase with age, decreased bone density, and fall risk. …”
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A lower atherogenic index of plasma was associated with a higher incidence of sarcopenia by Zhiping Duan, Yunda Huang, Xiaoling Liu, Huiyu Tang, Guihua Jiang, Wei Huang, Runfen Du, Dan Zhou, Hong Yang

“…Abstract Sarcopenia is an age-related muscle senescence disease that leads to functional limitations, physical disability and premature death in older adults. Atherogenic index of plasma (AIP) is a novel indicator of atherosclerotic status based on triglycerides and high-density lipoprotein cholesterol. …”
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Comprehensive Assessment of Specific Patient-Reported Outcome Measures for Hand and Wrist Conditions in Adults: A Scoping Review by S. Iskander, G. Halbesma, M.M. Hoogbergen, D. Young-Afat, I.J. Veldhuizen

“…Results: A total of 22 PROMs for hand and wrist conditions were identified, with the Disabilities of the Arm, Shoulder, and Hand (DASH) being the most frequently employed, followed by the Patient Rated Wrist Evaluation and QuickDASH. …”
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Platelet-rich fibrin and silver nano-particles loaded chitosan treatment for post- laminectomy epidural scar adhesions: in vivo rats study model by Samah Fouad, Awad Rizk, Esam Mosbah, Mostafa M. Nabeeh, Walaa Awadin, Ayman S. Elmezayyen, Ekramy Elmorsy, Adel Zaghloul

“…Abstract Objective Epidural scar fibrosis commonly leads to functional disability and pain following spinal surgery and is a prevalent manifestation of Failed Back Surgery Syndrome (FBSS). …”
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Global and regional burden of bloodstream infections caused by carbapenem-resistant Gram-negative bacteria in 2019: A systematic analysis from the MICROBE database by Lei Zha, Shirong Li, Jun Guo, Yixin Hu, Lingling Pan, Hanli Wang, Yun Zhou, Qiancheng Xu, Zhiwei Lu, Xiang Kong, Xinzhao Tong, Yusheng Cheng

“…The number and rate of deaths, as well as disability-adjusted life-years linked to bloodstream infections, were systematically analyzed. …”
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