Eptinezumab-jjmr, a humanized monoclonal specific to Calcitonin Gene Related Peptide, for the preventive treatment of migraine in adults by Amnon A. Berger, Joseph Keefe, Cain W. Stark, Matthew Moore, Giovanni F. Ramírez, Julia R. Cucarola, Andrew H. Han, Alan D. Kaye, Latha Ganti

“…It is a prevalent disorder that causes significant, worldwide disability, morbidity, suffering, and costs. The pathophysiology of migraines is actively studied, though recent research points to an initiating event causing migraine generation, that is then propagated by other brain regions, a significant one being the trigeminocervical complex. …”
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Application of Nanomaterial-Mediated Ferroptosis Regulation in Kidney Disease by Zhu J, Zhang Z, Chu Y, Xie Z, Zeng D, Jin L, Li L

“…Jiamin Zhu,1,* Zhen Zhang,1,2,* Yanhui Chu,1,* Zhongyin Xie,1 Dongmei Zeng,1 Lijiao Jin,1 Luxin Li1 1Heilongjiang Key Laboratory of Anti-Fibrosis Biotherapy, Mudanjiang Medical University, Mudanjiang, People’s Republic of China; 2School of First Clinical Medical College, Mudanjiang Medical University, Mudanjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Luxin Li, Heilongjiang Key Laboratory of Anti-Fibrosis Biotherapy, Mudanjiang Medical University, Mudanjiang, 157000, People’s Republic of China, Tel +86 13763617174, Email liluxin@mdjmu.edu.cnAbstract: Kidney diseases are a significant global cause of death and disability, resulting from the destruction of kidney structure and function due to an imbalance between the death of renal parenchymal cells and the proliferation or recruitment of maladaptive cells, caused by various pathogenic factors. …”
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Exploring the Mechanisms of Zhenbao Pills in the Treatment of Stroke through Network Pharmacology Combined with Mendelian Randomization by Yanhong Liu, Yunqi Hua, Xiaoe Jia

“…Background: Stroke causes substantial death and disability worldwide, challenging healthcare systems and impacting patients' lives. …”
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Prevalence of sexual dysfunction in HTLV-1 patients without spastic paraparesis and the association with psychiatric symptoms by Maedeh Kamrani, Narges Niazi Rad, Fariba Zemorshidi, Majid Khadem-Rezaiyan

“…Patients with spastic paraparesis, leukemia, and uveitis, and those with an expanded disability status scale (EDSS) score higher than 2 were excluded. …”
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Arthroscopic Rotator Cuff Restoration Using Sironix Suture Anchor: A Retrospective Observational Study by Krunal Shah, Ruchita Manwani, Ashok Kumar Moharana, Sachin Angrish, T. S. Deepak

“…Postoperatively, patients were followed up and functional outcomes were evaluated using the American Shoulder and Elbow Surgeons Standardization Shoulder Assessment (ASES), level of activity using the Simple Shoulder Test (SST) questionnaire, Quality of life using the Shoulder Pain and Disability Index (SPADI) scale, and Single Assessment Numerical Evaluation (SANE) score on a scale of 0–100. …”
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Global, regional, and national burden of children and adolescents with acute lymphoblastic leukemia from 1990 to 2021: a systematic analysis for the global burden of disease study... by Lei Wang, Xue Yao, Linhua Yang

“…Disease status and change were analyzed by learning about the prevalence, death, incidence, DALYs (disability-adjusted life years), percentage change, and the estimated annual percentage change (EAPC).ResultsIn 2021, there were 53,485 new cases of childhood and adolescent ALL, 23,991 deaths, and an estimated 1960,922 DALYs. …”
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Automated Fog Node Audit and Certification Scheme With Multiple Attestation Certificate Authorities by Shuaib Anath, Tahmid Quazi, Bashan Naidoo

“…This study examines the CA service availability in the FoNAC scheme, revealing that a single centralized attestation CA leads to a single point of failure that disables FoNAC and causes service bottlenecks. This paper proposes a distributed multiple attestation CA system to overcome these limitations. …”
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Food Neophobia and Two Facets of Orthorexia Among Women: Cross-Sectional Study by Tuba Yalçın, Seda Çiftçi, Elif Esra Ozturk

“…This cross-sectional study of 985 women aged 18 years and over was conducted using face-to-face questionnaires. Women who had a disability, had a chronic disease, or were pregnant or breastfeeding were excluded. …”
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Prevalence of Stunting among Children Aged 6–23 Months in Kemba Woreda, Southern Ethiopia: A Community Based Cross-Sectional Study by Eskezyiaw Agedew, Tefera Chane

“…Stunting (HAZ < −2 Z-score) is a major cause of disability preventing children who survive from reaching their full developmental potential. …”
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Clinical severity grading of NF2-related schwannomatosis by Anna C. Lawson McLean, Denise Löschner, Said Farschtschi, Nora F. Dengler, Steffen K. Rosahl

“…There is a wide range of disabilities these patients may suffer from and there is no validated clinical classification for disease severity. …”
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How Can ChatGPT Facilitate Teaching and Learning: Implications for Contemporary Education by Turgut Karakose, Tijen Tülübaş

“…When used with proper guidance and awareness, ChatGPT can facilitate the development of twenty-first century 4C skills (collaboration, communication, critical thinking, and creativity) as well as supporting students with disabilities or learning difficulties. ChatGPT can also help teachers enrich their instruction through providing them with creative ideas and solutions as well as helping them write lesson plans, develop presentations, reach content and materials tailored to their students’ needs. …”
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Evaluating Oral Health Status, Oral Lesions Prevalence, and Oral Health Impact Profile-14 among Tobacco Industry Workers by Grandhi Srujananjali, K. Ramya, Roja Lakshmi Karri, Krishna Sahi Bonthagarla, Akkineni Bhavya Sree, Yannam Mounika

“…Notably, a moderate level of oral health impact was observed (OHIP-14: 10.51), with physical pain and disability having the highest impact. The prevalence of oral lesions, although relatively low (84.4% with no lesions), suggests the importance of tailored oral health management. …”
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Exploring the enigma of low prevalence of post-traumatic stress disorder in India by Ateev S. Chandna, Satish Suhas, Rahul Patley, Damodharan Dinakaran, Narayana Manjunatha, Girish N. Rao, Gopalkrishna Gururaj, Mathew Varghese, Vivek Benegal, NMHS National Collaborators Group

“…The study also highlighted a high rate of comorbid mood and anxiety disorders, substantial disability, poor treatment-seeking behavior, and significant suicidal risk among individuals with PTSD. …”
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Clinical Efficacy of Percutaneous Kyphoplasty Combined with Calcitriol and Calcium in the Treatment of Traumatic Nonosteoporotic Vertebral Compression Fractures by Shouqian Dai, Xin Lu, Ningning Dai, Xiu Shi, Peng Yang, Peng Peng, Feng Xu

“…The visual analog scale (VAS) pain scores, Oswestry Disability Index (ODI) scores, the height of the anterior edge of the vertebral body, Cobb’s angle, and the level of the bone mineral density of the two groups of TNVCF patients before surgery were recorded and compared, one and six months after surgery. …”
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Proton magnetic resonance spectroscopy-based evaluation of metabolic abnormalities in the right dorsolateral prefrontal cortex and caudate nucleus in treatment-naïve patients with... by Gagan Hans, Uma Sharma, Novy Gupte, Ragul Ganesh, Vaibhav Patil, Pratap Sharan

“…The level of tNAA in DLPFC significantly correlated with the disability level (WHO-DAS) of the patients. Conclusions: The present study demonstrates abnormalities in the metabolic profile of an important region, DLPFC of the CSTC circuit, which is suggestive of neurodegeneration in the region in OCD patients.…”
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Factors associated with memory of informal caregivers: A scoping review protocol. by Dingyue Wang, Sharron Rushton, Leila Ledbetter, Margaret Graton, Kimberly Ramos, Cristina C Hendrix

“…Studies will be included if (1) the studies focus on home-based unpaid long term family caregiving; (2) study participants (patients), of any age, have one (or more) chronic illness or disability and receive care from a caregiver for 6 months or more; (3) caregivers are adults (> = 18 years of age). …”
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Children Who Experience Unintentional Injuries: Their Functional Profiles by Sara Rosenblum, Tal Nardi-Moses, Helly Goez, Naor Demeter

“…Sixty percent of the children in the research (injured) group had been prediagnosed with learning disabilities or attention deficit hyperactivity disorders, compared with no child in the control (uninjured) group. …”
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Role of CTCF protein in regulating FMR1 locus transcription. by Stella Lanni, Martina Goracci, Loredana Borrelli, Giorgia Mancano, Pietro Chiurazzi, Umberto Moscato, Fabrizio Ferrè, Manuela Helmer-Citterich, Elisabetta Tabolacci, Giovanni Neri

“…Fragile X syndrome (FXS), the leading cause of inherited intellectual disability, is caused by epigenetic silencing of the FMR1 gene, through expansion and methylation of a CGG triplet repeat (methylated full mutation). …”
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The global health and economic burden of chikungunya from 2011 to 2020: a model-driven analysis on the impact of an emerging vector-borne disease by Adrianne Marije de Roo, Gerard Timmy Vondeling, Martijn Boer, Kristy Murray, Maarten Jacobus Postma

“…This study aims to provide a comprehensive overview of the chikungunya burden worldwide.Methods We analysed the global burden of chikungunya between 2011 and 2020 and calculated disability-adjusted life years (DALYs) and direct and indirect costs using a data-driven simulation model. …”
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PEDIATRIC FRACTURES IN A TERTIARY PUBLIC HOSPITAL: WHAT ARE WE DEALING WITH? by Leonardo Lima de Almeida, Edgard Eduard Engel, Jose Batista Volpon

“…Fractures, while not the most lethal lesion, may result in physical variable disability; publications show that about 30% of children experience fractures by skeletal maturity, primarily from low-energy trauma. …”
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