Indicators for the evaluation of musculoskeletal trauma systems: A scoping review and Delphi study. by M Dworkin, K J Agarwal-Harding, M Joseph, G Cahill, D Konadu-Yeboah, E Makasa, C Mock, MSK Indicator Group

“…Musculoskeletal trauma results in the majority of post-traumatic morbidity and disability globally. The literature has reported many performance indicators relating to trauma care, but few specific to musculoskeletal injuries.…”
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A case report of exacerbation of extrapyramidal symptoms following the switch from risperidone to paliperidone during valproate therapy by Emi Hata, Masatoshi Miyauchi, Nobuhiko Noguchi, Takeshi Asami

“…We report a case of a 48-year-old Japanese male with epilepsy-associated psychosis and mild intellectual disability who experienced severe EPS during a gradual cross-titration from risperidone to paliperidone while on valproate therapy. …”
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Milestones and Timescale of Poststroke Recovery: A Cohort Study by Marianna Loi, Alberto Zaliani, Marta Abbamonte, Elena P. Ferrari, Roberto Maestri, Luigi Trojano, Pietro Balbi

“…As many stroke survivors chronically show severe disability, increase in economic, social, and medical burden could be expected in the future. …”
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Effect of metformin on the clinical outcomes of stroke in patients with diabetes: a systematic review and meta-analysis by Jianming Zhu, Jun Wen, Zhihua Huang, Jianyi Liu, Fuqun Luo, Yizhi Guo, Yandeng Li

“…Objectives Stroke is a major cause of death and disability globally, especially among diabetic patients. …”
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Comparing the Fiscal Consequences of Controlled and Uncontrolled Osteoarthritis Pain Applying a UK Public Economic Perspective by Rui Martins, Nikos Kotsopoulos, Melodi Kosaner Kließ, Craig Beck, Lucy Abraham, Samuel Large, Patricia Schepman, Mark P. Connolly

“…The likelihood of employment, long-term sickness, disability, and early retirement in those with controlled pain used publicly available UK data. …”
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Burden and trends of dietary iron deficiency in the Middle East and North Africa region, 1990–2021 by Saeid Safiri, Saeid Safiri, Fatemeh Amiri, Nahid Karamzad, Nahid Karamzad, Mark J. M. Sullman, Mark J. M. Sullman, Ali-Asghar Kolahi, Morteza Abdollahi

“…ObjectiveTo assess the burden of dietary iron deficiency in the Middle East and North Africa (MENA) region, focusing on prevalence and years lived with disability (YLD) in 2021 and their changes since 1990.MethodsData from the Global Burden of Disease (GBD) 2021 study were utilised to report counts and age-standardised rates for prevalence and YLD related to dietary iron deficiency. …”
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Prevalence, predisposing factors, and turnover intention related to low back pain among health workers in Accra, Ghana. by Philip Apraku Tawiah, Emmanuel Appiah-Brempong, Paul Okyere, Geoffrey Adu-Fosu, Mary Eyram Ashinyo

“…<h4>Background</h4>Globally, low back pain (LBP) is responsible for disability among 60.1 million people. Health workers face a higher likelihood of being exposed to LBP compared to employees in the construction and manufacturing sectors. …”
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Learning curve and complications of unilateral biportal endoscopy–unilateral laminectomy bilateral decompression for lumbar spinal stenosis by Jiashen Shao, Zihan Fan, Hai Meng, Qi Fei

“…The visual analogue scale and Oswestry Disability Index scores at the last follow-up showed significant improvement in both groups as compared with the preoperative period (P <⁠0.05). …”
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Epigene functional diversity: isoform usage, disordered domain content, and variable binding partners by Leroy Bondhus, Aileen A. Nava, Isabelle S. Liu, Valerie A. Arboleda

“…Additionally, we assessed the specificity of their expression profiles and showed epigenes are more ubiquitously expressed consistent with their enrichment in pediatric syndromes with intellectual disability, multiorgan dysfunction, and developmental delay. …”
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Trend in burden of rheumatoid arthritis in China from 1990 to 2021 by WEN Jiaxin，JIANG Junpeng，FENG Min，SHEN Xiaochen，LI Xiaoyin

“…Methods:Data of Global Burden of Disease Study 2021 were collected, and the incidence, mortality and disability-adjusted life years (DALY) of RA in China from 1990 to 2021 were analyzed and compared with global and different Socio-demographic Index (SDI) regions. …”
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The prevalence of latex sensitisation and allergy and associated risk factors among healthcare workers using hypoallergenic latex gloves at King Edward VIII Hospital, KwaZulu-Natal... by Shumani Makwarela Phaswana, Saloshni Naidoo

“…In addition more cohort analysis is required to better understand the chronicity of illness and disability associated with latex allergy.…”
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Safety and Efficacy of Polyetheretherketone (PEEK) Cages and Cadaveric Allografts in Transforaminal Lumbar Interbody Fusion (TLIF) for Treating Lumbar Pyogenic Spondylodiscitis by Huo-Liang Zheng, Bo Li, Shao-Kuan Song, Peng-Bo Chen, Xin-Feng Zheng, Lei-Sheng Jiang, Sheng-Dan Jiang

“…The clinical outcome was evaluated using a visual analog scale (VAS) and the Oswestry Disability Index (ODI), and neurological outcomes were appraised based on Frankel grades. …”
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Understanding the Process and Challenges for Return-to-Work Post-Hematopoietic Cell Transplantation from a Musculoskeletal Perspective: A Narrative Review by Jaleel Mohammed, Anne Gonzales, Hadeel R. Bakhsh, Volkova Alisa Georgievna, Jayanti Rai, Bindu Kancharla, Shahrukh K. Hashmi

“…In line with the International Classification of Functioning, Disability, and Health (ICF) recommendations, a RTW assessment combined with a job evaluation helps healthcare professionals and stakeholders to understand the unique challenges and strengths of a patient and thereby design an individualized therapy approach.…”
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Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder by Claudia Fuchs, Laura Gennaccaro, Stefania Trazzi, Stefano Bastianini, Simone Bettini, Viviana Lo Martire, Elisa Ren, Giorgio Medici, Giovanna Zoccoli, Roberto Rimondini, Elisabetta Ciani

“…CDKL5 disorder primarily affects girls and is characterized by early-onset epileptic seizures, gross motor impairment, intellectual disability, and autistic features. Although all CDKL5 female patients are heterozygous, the most valid disease-related model, the heterozygous female Cdkl5 knockout (Cdkl5 +/−) mouse, has been little characterized. …”
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Assessing the inflammation in pediatric MOGAD: Significance of CSF HMGB1 and related biomarkers by Xin Wang, Ruibin Zhao, Jiayu Fan, Chong Liu, Li Zhang, Huafang Yang, Weiyi Wang

“…We recruited 30 patients with MOGAD (20 in the acute phase and 10 in remission) and 10 control patients with noninflammatory demyelinating disease. The expanded disability status scale (EDSS) was used to assess disease severity.ResultsNLRP3, HMGB1, and IL-6 levels in the CSF were significantly higher in patients with MOGAD during the acute phase than in remission (P &lt; 0.05, P &lt; 0.05, P &lt; 0.05) and the control group (P &lt; 0.01, P &lt; 0.0001, P &lt; 0.01). …”
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Extracecellulr vesicles (EVs) microRNAs (miRNAs) derived from mesenchymal stem cells (MSCs) in osteoarthritis (OA); detailed role in pathogenesis and possible therapeutics by Seyede Sara Pakdaman Kolour, Saeide Nematollahi, Masoud Dehbozorgi, Farnaz Fattahi, Fatemeh Movahed, Neda Esfandiari, Mohammad Saeed Kahrizi, Nima Ghavamikia, Bahareh Salmanian Hajiagha

“…The primary cause of pain and disability in the world is osteoarthritis (OA), a common joint disease characterized by the primary pathological alteration in articular cartilage deterioration. …”
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Global, regional, and national survey on burden and Quality of Care Index (QCI) of orofacial clefts: Global burden of disease systematic analysis 1990-2019. by Ahmad Sofi-Mahmudi, Erfan Shamsoddin, Sahar Khademioore, Yeganeh Khazaei, Amin Vahdati, Marcos Roberto Tovani-Palone

“…By utilizing data on incidence, prevalence, years of life lost, and years lived with disability, we defined four ratios to indirectly reflect the quality of healthcare. …”
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Usefulness of the Brief Scale for Psychiatric Problems in Orthopaedic Patients (BS-POP) for Predicting Poor Outcomes in Patients Undergoing Lumbar Decompression Surgery by Kazuyuki Watanabe, Koji Otani, Takuya Nikaido, Kinshi Kato, Hiroshi Kobayashi, Junichi Handa, Shoji Yabuki, Shin-Ichi Kikuchi, Shin-Ichi Konno

“…The secondary outcomes were NRS scores for low back pain, leg pain, and leg numbness and scores on the Roland–Morris Disability Questionnaire (RDQ). BS-POP was used to detect psychiatric problems before surgery. …”
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Platelet-rich fibrin and silver nano-particles loaded chitosan treatment for post- laminectomy epidural scar adhesions: in vivo rats study model by Samah Fouad, Awad Rizk, Esam Mosbah, Mostafa M. Nabeeh, Walaa Awadin, Ayman S. Elmezayyen, Ekramy Elmorsy, Adel Zaghloul

“…Abstract Objective Epidural scar fibrosis commonly leads to functional disability and pain following spinal surgery and is a prevalent manifestation of Failed Back Surgery Syndrome (FBSS). …”
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Follicular Helper CD4+ T Cells, Follicular Regulatory CD4+ T Cells, and Inducible Costimulator and Their Roles in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis by Xue Zhang, Ruli Ge, Hongliang Chen, Maxwell Ahiafor, Bin Liu, Jinbo Chen, Xueli Fan

“…Multiple sclerosis (MS) is a severe autoimmune disease that affects the central nervous system and results in disability, mediated by autoreactive T cells with evolving evidence of a remarkable contribution from humoral responses. …”
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