Modeling Survival Time to Death among Stroke Patients at Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study by Bikiltu Wakuma Negasa, Teramaj Wongel Wotale, Mesfin Esayas Lelisho, Legesse Kassa Debusho, Kibrealem Sisay, Wubishet Gezimu

“…Every year, about 15 million people worldwide suffer from a stroke, with five million of them suffering from some form of permanent physical disability. Globally, stroke is the second-leading cause of death following ischemic heart disease. …”
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Maternal Third Delay and Associated Factors among Women Admitted for Emergency Obstetric Care in Public Hospitals in Sidama Regional State, Ethiopia by Esuyawkal Mislu, Ali Seid, Nigus Bililign, Terefe Woyo, Dubale Dulla

“…Timing to get obstetric care is critical in preventing maternal death and disability. Maternal third delay, the delay in receiving care after reaching health facilities, involves factors related to organization, quality of care, patient referral, and availability of staff and equipment. …”
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Epidemiology of urinary tract infections in the Middle East and North Africa, 1990–2021 by Fatemeh Amiri, Saeid Safiri, Reza Aletaha, Mark J. M. Sullman, Kamaleddin Hassanzadeh, Ali-Asghar Kolahi, Shahnam Arshi

“…Abstract Objective This research reports the incidence, mortality, and disability-adjusted life years (DALYs) associated with urinary tract infections (UTIs) in the Middle East and North Africa (MENA) region, stratified by sex, age, and Socio-demographic Index (SDI) from 1990 to 2021. …”
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Fear of Pain as a Predictor for Postoperative Pain Intensity among the Patients Undergoing Thoracoscopic Surgery by Yang Luo, Jingting He, Lihong Bao, Heng Meng, Cuihuan Hu, Quan Chen

“…Fear of pain (FOP) has been recognized as an influential moderator and determinant of the perception and disability of chronic pain. However, studies on FOP in postoperative acute pain are few and inconsistent. …”
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Navigating the Risk Landscape in ST-Elevation Myocardial Infarction Patients Postpercutaneous Coronary Intervention: A Narrative Review by Utkarsh Gaur, Charuta Gadkari, Aditya Pundkar

“…The ST-Elevation Myocardial Infarction (STEMI) remains one of the major contributors to death and disability worldwide. The primary Percutaneous Coronary Intervention (pPCI) has gained wide adoption as the preferred reperfusion strategy over time. …”
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Adipocytokines in Rheumatoid Arthritis: The Hidden Link between Inflammation and Cardiometabolic Comorbidities by Piero Ruscitti, Paola Di Benedetto, Onorina Berardicurti, Vasiliki Liakouli, Francesco Carubbi, Paola Cipriani, Roberto Giacomelli

“…Rheumatoid arthritis is a chronic autoimmune disease affecting typically synovial joints and leading to progressive articular damage, disability, and reduced quality of life. Despite better recent therapeutic strategies improving long-term outcomes, RA is associated with a high rate of comorbidities, infections, malignancies, and cardiovascular disease (CVD). …”
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Impact of Scleroderma‐Associated Autoantibodies on Clinical Outcome Assessments: Post Hoc Analysis From a Randomised, Double‐blind, Placebo‐controlled, Phase 3 Trial of Tocilizumab... by Basmah Al Dulaijan, Suiyuan Huang, Celia J. F. Lin, Christopher P. Denton, Dinesh Khanna

“…We assessed the impact of baseline SSc‐Abs on six COAs: modified Rodnan skin score (mRSS), forced vital capacity (FVC%), Health Assessment Questionnaire Disability Index, patient and clinical global assessments, and American College of Rheumatology (ACR) Composite Response Index in Systemic Sclerosis (CRISS). …”
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RHOBTB2 Variant p.Arg511Gln Causes Developmental and Epileptic Encephalopathy Type 64 in an Infant: A Case Report and Hotspot Variant Analysis by Qian Liu, Feifei Li, Qin Ruan, Nana Wang, Zhengjun Fan

“…Variants in the Rho‐related BTB domain‐containing 2 gene (RHOBTB2) can lead to DEE64, which is characterized by early‐onset epilepsy, varying degrees of motor developmental delay and intellectual disability, microcephaly, and movement disorders. More than half of the variants are located at Arg483 and Arg511 within the BTB domain; however, the underlying mechanism of action of these hotspot variants remains unexplored. …”
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The global, regional burden of pancreatic cancer and its attributable risk factors from 1990 to 2021 by Weidong Yu, Danyi Zhou, Fanhao Meng, Jinjing Wang, Bo Wang, Jianling Qiang, Lijun Shen, Maofeng Wang, Hezhi Fang

“…Methods The degree and change patterns of exposure as well as the attributable cancer burden, including incidence, mortality, disability-adjusted life years (DALYs), and prevalence in global and regional, by sex, age, year, for pancreatic cancer, with the data extracted from the Global Burden of Diseases Study (GBD) 2021. …”
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Biodegradable Polymer DES (Ultimaster) vs. Magnesium Bioresorbable Scaffold (BRS Magmaris) in Diabetic Population with NSTE-ACS: A One-Year Clinical Outcome of Two Sirolimus-Elutin... by Piotr Rola, Adrian Włodarczak, Mateusz Barycki, Marek Szudrowicz, Magdalena Łanocha, Jan Jakub Kulczycki, Karol Turkiewicz, Katarzyna Woźnica, Maciej Lesiak, Adrian Doroszko

“…Cardiovascular disease (CVD) with significant involvement of coronary artery disease (CAD) remains a major cause of death and disability among the diabetic population. Although percutaneous coronary intervention (PCI) continues to evolve, type 2 diabetes mellitus (T2DM) is a well-established marker of poor clinical prognosis after PCI, which is mainly attributed to the rapid progression of atherosclerosis requiring recurrent revascularizations. …”
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A Randomized Controlled Trial of the Treatment of Rotator Cuff Tears with Bone Marrow Concentrate and Platelet Products Compared to Exercise Therapy: A Midterm Analysis by Christopher Centeno, Zachary Fausel, Ian Stemper, Ugochi Azuike, Ehren Dodson

“…Patients completed the Disability of the Arm, Shoulder and Hand (DASH) scores as the primary outcome measure. …”
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Ischemic Strokes: Observations from a Hospital Based Stroke Registry in Bangladesh by Nirmalendu Bikash Bhowmik, Aamir Abbas, Mohammad Saifuddin, Md. Rashedul Islam, Rumana Habib, Aminur Rahman, Md. Amirul Haque, Zahid Hassan, Mohammad Wasay

“…Mortality was low but most of patient had moderate to severe disability at discharge. Age, mRS, systolic blood pressure, urinary tract infection, pneumonia, and stroke severity influenced the Barthel score.…”
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Case report: Trauma-induced Klebsiella pneumoniae invasive syndrome presenting with liver abscess, lung abscess, endophthalmitis, and purulent meningitis by Hong-qiao Chen, Zhen-hua Mo, Wu-xiao Wei

“…By highlighting the role of trauma as a potential trigger for KPIS, particularly in high-risk populations such as individuals with diabetes, this study seeks to provide valuable insights for improving clinical outcomes and promoting public health awareness.BackgroundKlebsiella pneumoniae invasive syndrome is a multi-organ infectious disease commonly associated with complications such as liver abscess, lung abscess, endophthalmitis, and purulent meningitis, with high mortality and disability rates. In recent years, the incidence of KPIS has been increasing, particularly in the Asia-Pacific region, and is closely linked to hypervirulent Klebsiella pneumoniae (hvKp) infections. …”
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Prevalence, Patterns, and Factors Associated with Peripheral Neuropathies among Diabetic Patients at Tertiary Hospital in the Kilimanjaro Region: Descriptive Cross-Sectional Study... by Ahlam A. Amour, Nyasatu Chamba, Johnstone Kayandabila, Isaack A. Lyaruu, Dekker Marieke, Elichilia R. Shao, William Howlett

“…Diabetic peripheral neuropathy (DPN) is a common microvascular complication of diabetes mellitus (DM) and may progress to diabetic foot, which frequently leads to amputation and/or disability and death. Data is scanty on the burden of diabetic peripheral neuropathy in Tanzania. …”
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Low-density Lipoproteins and Degrees of Cardiovascular Risk in Adults over 40 Years of Age: Case-control Study by Abel Pérez Pavón, Francisco Sánchez Hernández, Karla Doriam Gámez Ávalos, Donovan Casas Patiño, Alejandra Rodríguez Torres

“…<strong>Foundation:</strong> cardiovascular diseases are the main cause of death and disability in the world. Its incidence and prevalence has increased over the last decade and accounts for a third of all deaths. …”
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Successful open defecation-free intervention in low- and middle-income countries: a qualitative synthesis systematic review protocol by Vera Yulyani, Iswanto Iswanto, Daniel Daniel, Fitrina Mahardani Kusumaningrum, Fatwa Sari Tetra Dewi

“…Research examining sanitation interventions in schools, shelters, disability communities and virtual communities was excluded, as the review focused exclusively on community-based interventions. …”
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Thrombin Generation in Acute Ischaemic Stroke by Ibrahim O. Balogun, Lara N. Roberts, Raj Patel, Rohan Pathansali, Lalit Kalra, Roopen Arya

“…Stroke remains a global leading cause of death and disability. Traditional description of plasma biology in the aftermath of acute ischaemic stroke favours development of hypercoagulability, resulting from complex interplay between plasma and endothelial factors. …”
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Assessment of ABCDE approach knowledge among residents and interns in multiple Egyptian hospitals, a cross-sectional study by Mohamed Saad Rakab, Ahmed B. Zaid, Malak Abbas Hamadein, Salma Abbas Hamadein, Mahmoud Abd Elgawad Ashour, Alaa Samir El-Shamia, Dina Ayman Mostafa, Rahma Mogahed Rateb, Marwa Abdelrahman Elashry, Mennat-Allah Mostafa El-Badawy, Rehab Shaheen Bahram Shaheen

“…Abstract Background The Airway, Breathing, Circulation, Disability, and Exposure (ABCDE) approach is crucial in emergency care, but there may be variability in adherence among healthcare professionals. …”
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3-MA attenuates collagen-induced arthritis in vivo via anti-inflammatory effect and autophagy inhibition by Chong Feng, Zi-rou Wang, Chen-yu Li, Xiang-yu Zhang, Xin-xing Wang

“…RA results in synovitis and cartilage/bone damage, even disability which aggravates the health burden. Many drugs are used to relieve RA, such as glucocorticoids (GCs), non-steroidal anti-inflammatory drugs (NSAIDs), and disease-modifying anti-rheumatic drugs (DMARDs) in the clinical treatment. …”
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Defining New Research Questions and Protocols in the Field of Traumatic Brain Injury through Public Engagement: Preliminary Results and Review of the Literature by Shumaila Hasan, Aswin Chari, Mario Ganau, Chris Uff

“…Traumatic brain injury (TBI) is the most common cause of death and disability in the age group below 40 years. The financial cost of loss of earnings and medical care presents a massive burden to family, society, social care, and healthcare, the cost of which is estimated at £1 billion per annum (about brain injury (online)). …”
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