Patient-Reported Outcomes in Children Undergoing the Modified Green Procedure for Treating Sprengel’s Deformity: Results from a Multicentric Study by Giovanni Trisolino, Paola Zarantonello, Marco Todisco, Giovanni Luigi Di Gennaro, Grazia Chiara Menozzi, Philipp Scheider, Alessandro Depaoli, Diego Antonioli, Gino Rocca, Sebastian Farr

“…Several dedicated questionnaires such as QuickDASH, the Shoulder Pain Index and the Shoulder Disability Index (SPADI) and finally the UCLA Shoulder Scale were submitted to assess the quality of life of the subjects and the ability to practice certain activities, including work and sports. …”
Get full text

Standards in Neurological Rehabilitation, June 1997 by Michael P. Barnes, European Federation of Neurological Societies Task Force

“…The regional specialist service would cater for people with more complicated and severe disabilities, including spinal injury and severe brain injury. …”
Get full text

Neuroprotective Efficacy of <i>Astragalus mongholicus</i> in Ischemic Stroke: Antioxidant and Anti-Inflammatory Mechanisms by Yongjae Hong, Geon Ko, Yeong-Jae Jeon, Hyeon-Man Baek, Juni Lee, Donghun Lee, Jieun Park, Jaehong Kim, Keun-A Chang

“…Stroke affects over 12 million people annually, leading to high mortality, long-term disability, and substantial healthcare costs. Although East Asian herbal medicines are widely used for stroke treatment, the pathways of operation they use remain poorly understood. …”
Get full text

Comparison of Accuracy in Expert Clinical Examination versus Magnetic Resonance Imaging and Arthroscopic Exam in Diagnosis of Meniscal Tear by Seyed Ali Hashemi, Mohammad Reza Ranjbar, Mohammad Tahami, Reza Shahriarirad, Amirhossein Erfani

“…Torn menisci or ligamentous structures within the knee cause significant pain and disability and thus require expeditious management. …”
Get full text

Reducing medical cannabis use risk among Veterans: A descriptive study by Laura M. Harris-Lane, Mitchell Sheehy, Courtney A. Loveless, Joshua A. Rash, David P. Storey, Gregory K. Tippin, Vikas Parihar, Nick Harris

“…Results Veterans who currently use cannabis were more likely to be unemployed (z = 3.62, p < .01), released as a Non-Commissioned Officer (z = -3.83, p < .01), and unable to work due a disability (z = -3.43, p < .01) than Veterans who do not currently use. …”
Get full text

Learning Curve of Uniportal Compared With Biportal Endoscopic Techniques for the Treatment of Lumbar Disc Herniation by Yuquan Liu, Xiang Li, Haining Tan, Xinyi Hao, Bin Zhu, Yong Yang, Lingjia Yu

“…Secondary outcomes assessing endoscopic prowess include surgical outcomes, such as fluoroscopy usage times, postoperative hospital stays, the incidence of complications, and clinical outcomes, including visual analog scale (VAS) scores for back and leg pain, Oswestry disability index (ODI) score and modified MacNab criteria. …”
Get full text

Predictors of the Short‐Term Outcomes of Guillain–Barré Syndrome: Exploring Electrodiagnostic and Clinical Features by Yi‐Hsiang Chen, Chia‐Lun Wu, Wei‐Chieh Weng, Yi‐Chia Wei

“…The patients were stratified into two groups by their scores on the GBS Disability Scale: good (score ≤ 2) and poor (score > 2) outcome groups. …”
Get full text

Global, regional and national burdens of bipolar disorders in adolescents and young adults: a trend analysis from 1990 to 2019 by Yifan Chen, Long Sun, Meiqi Wang, Yunxi Zhong, Xiaoying Su, Qixiu Li, Ziming Shao

“…The numbers, rates per 100 000 population, average annual percentage changes (AAPCs) of incidence, prevalence and years lived with disability (YLDs) of bipolar disorder are reported at the global, regional and national levels among individuals aged 10–24 years. …”
Get full text

A Novel CRYBB2 Stopgain Mutation Causing Congenital Autosomal Dominant Cataract in a Chinese Family by Yu Zhou, Yaru Zhai, Lulin Huang, Bo Gong, Jie Li, Fang Hao, Zhengzheng Wu, Yi Shi, Yin Yang

“…Congenital cataract is the most common cause of the visual disability and blindness in childhood. This study aimed to identify gene mutations responsible for autosomal dominant congenital cataract (ADCC) in a Chinese family using next-generation sequencing technology. …”
Get full text

Functional and Cognitive Impairment in Patients with Relapsing–Remitting Multiple Sclerosis: Cognitive Tests and Plasma Neurofilament Light Chain Levels by Elina Polunosika, Joel Simren, Arta Akmene, Nikita Klimovskis, Kaj Blennow, Daina Pastare, Henrik Zetterberg, Renars Erts, Guntis Karelis

“…In the MS group, the functional status was determined using the Expanded Disability Status Scale (EDSS), and neurofilament light chain levels in plasma (pNfL) were detected using single molecule array (Simoa) technology. …”
Get full text

Systematic analysis and prediction of the burden of Alzheimer’s disease and other dementias caused by hyperglycemia by Dongying He, Dongying He, Manting Liu, Yujin Tang, Xiaona Tian, Lisi Zhou, Yizhen Chen, Xiaoxia Liu, Xiaoxia Liu

“…A Shiny platform was developed to visualize the disease burden and trends across 204 countries and regions.ResultsIn 2021, approximately 15% of ADOD deaths and disability-adjusted life years (DALYs) were attributed to HFPG, a 271.05% increase from 1990. …”
Get full text

Cost-effectiveness of leveraging existing HIV primary health systems and community health workers for hypertension screening and treatment in Africa: An individual-based modeling s... by Matthew D Hickey, James Ayieko, Jane Kabami, Asiphas Owaraganise, Elijah Kakande, Sabina Ogachi, Colette I Aoko, Erick M Wafula, Norton Sang, Helen Sunday, Paul Revill, Loveleen Bansi-Matharu, Starley B Shade, Gabriel Chamie, Laura B Balzer, Maya L Petersen, Diane V Havlir, Moses R Kamya, Andrew N Phillips

“…For our primary analysis, we used a cost-effectiveness threshold of US $500 per disability-adjusted life-year (DALY) averted, a 3% annual discount rate, and a 50-year time horizon. …”
Get full text

Deciphering the role of miRNA-mRNA interactions in cerebral vasospasm post intracranial hemorrhage by Xiang Chu, Xiang Chu, Xiyan Zhu, Honghao Xu, Wenbing Zhao, Debin Guo, Xing Chen, Jinze Wu, Lei Li, Hao Wang, Jun Fei

“…Cerebral vasospasm (CVS), a serious complication following subarachnoid hemorrhage, is associated with high rates of mortality and disability. Emerging evidence suggests that abnormal miRNA and mRNA are involved in the development of CVS. …”
Get full text

Genetic Polymorphisms of Interleukin-1 Alpha and the Vitamin D Receptor in Mexican Mestizo Patients with Intervertebral Disc Degeneration by Salvador Cervin Serrano, Dalia González Villareal, Maribel Aguilar-Medina, Jose Guillermo Romero-Navarro, Jose Geovanni Romero Quintana, Eliakym Arámbula Meraz, Ignacio Osuna Ramírez, Veronica Picos-Cárdenas, Julio Granados, Iris Estrada-García, Guzman Sánchez-Schmitz, Rosalío Ramos-Payán

“…Intervertebral disc degeneration (IDD) is the most common diagnosis in patients with back pain, a leading cause of musculoskeletal disability worldwide. Several conditions, such as occupational activities, gender, age, and obesity, have been associated with IDD. …”
Get full text

The search for a blood-based biomarker for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS): from biochemistry to electrophysiology by Krista S. P. Clarke, Caroline C. Kingdon, Michael Pycraft Hughes, Eliana Mattos Lacerda, Rebecca Lewis, Emily J. Kruchek, Robert A. Dorey, Fatima H. Labeed

“…Without a quantitative biomarker, trivialisation, scepticism, marginalisation, and misunderstanding of ME/CFS continues despite the significant disability for many. One in four individuals are bed-bound for long periods of time, others have difficulties maintaining a job/attending school, incurring individual income losses of thousands, while few participate in social activities. …”
Get full text

Methylprednisolone substituted lipid nanoparticles deliver C3 transferase mRNA for combined treatment of spinal cord injury by Haoru Dong, Zongxing He, Shiyi Cai, Haiqiang Ma, Lili Su, Jianfeng Li, Huiying Yang, Rong Xie

“…Abstract Spinal cord injury (SCI), characterized by the disruption of neural pathways and an increase in inflammatory cell infiltration, leads to profound and lasting neurological deficits, with a high risk of resulting in permanent disability. Currently, the therapeutic landscape for SCI is notably sparse, with limited effective treatment options available. …”
Get full text

Trends and distribution patterns of infant mortality and maternal HIV positivity in South Africa: A decade review (2007 - 2016) by M Makhele, N Ledibane, H Ramatsoma, A Musekiwa

“…We recommend the use of disability-adjusted life expectancy in SA to measure population health and introduce robust data sets that can better inform policy. …”
Get full text

Development and external validation of a dynamic nomogram for predicting the risk of functional outcome after 90 days in patients with acute intracerebral hemorrhage by Shaojie Li, Hongjian Li, Jiani Chen, Baofang Wu, Jiayin Wang, Chaocan Hong, Changhu Yan, Weizhi Qiu, Yasong Li, Hongzhi Gao

“…Background and purposeIntracerebral hemorrhage remains a significant cause of death and disability worldwide, highlighting the urgent need for accurate prognostic assessments to optimize patient management. …”
Get full text

践行数智化健康管理理念，提升我国卒中患者管理质量和效率 Implementing the Concept of Digital Intelligent Health Management to Enhance the Quality and Efficiency of Stroke Patient Management in China... by 李星明1，宋西方2，武剑3，4，邱月4，杨宇彤1，过君君1，高雨润1，周立涵1 (LI Xingming1, SONG Xifang2, WU Jian3,4, QIU Yue4, YANG Yutong1, GUO Junjun1, GAO Yurun1, ZHOU Lihan1)

“…Abstract: The prevalence and mortality of stroke continue to rise and have become the primary cause of death and disability among residents in China. Despite advances in emergency care and monitoring technology have improved patient survival rates, the long-term management outcomes and quality of life for stroke patients still need improvement. …”
Get full text

Transforaminal Endoscopic Lumbar Discectomy versus Coblation Nucleoplasty Combined with Collagenase Chemonucleolysis for Lumbar Disc Herniation with Grade I Degenerative Spondyloli... by Yuyu Guo, Liuhu Han, Tingting Li, Bingbing Xu, Penghui Ke, Jun Hu, Rongyi Zhang, Yan Guo, Long Zhao, Likui Wang

“…The surgical efficacy was evaluated according to the visual analogue scale (VAS), oswestry disability index (ODI), quality of recovery-15 (QoR-15), and modified MacNab criteria. …”
Get full text