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1521
Cell-Based Therapies for the Treatment of Shoulder and Elbow Tendinopathies: A Scoping Review
Published 2021-01-01“…Tendinopathies are a common cause of disability among the general population, and their management is challenging due to the degenerative nature of these disorders. …”
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1522
Characteristics and Outcomes of Younger Adults with Embolic Stroke of Undetermined Source (ESUS): A Retrospective Study
Published 2019-01-01“…Although younger adults with ESUS had fewer risk factors, there were no significant differences in neurologic disability or mortality at discharge, stroke severity, or median length of stay.…”
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1523
The effect of cheese intake on osteoarthritis: a Mendelian randomization study
Published 2024-12-01“…Introduction Osteoarthritis (OA) is a debilitating chronic disease with a high prevalence, characterized by progressive degeneration of articular cartilage that leads to joint dysfunction, pain, and disability. Observational studies investigating the link between cheese intake and OA have yielded inconclusive results and may be susceptible to confounding. …”
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1524
Evolutionary constrained genes associated with autism spectrum disorder across 2,054 nonhuman primate genomes
Published 2025-01-01“…Constraint was also observed across genes associated with intellectual disability (p = 1.1 × 10− 46), epilepsy (p = 2.1 × 10− 33) and schizophrenia (p = 4.2 × 10− 45), and for an overlapping neurodevelopmental gene set (p = 4.0 × 10− 10). …”
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1525
Stroke Induces a BDNF-Dependent Improvement in Cognitive Flexibility in Aged Mice
Published 2019-01-01“…Stroke remains a leading cause of disability worldwide. Recently, we have established an animal model of stroke that results in delayed impairment in spatial memory, allowing us to better investigate cognitive deficits. …”
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1526
Clinical Outcomes of “U” Route Transforaminal Percutaneous Endoscopic Lumbar Discectomy in Chronic Pain Patients with Lumbar Spinal Stenosis Combined with Disc Herniation
Published 2021-01-01“…Minimum dura sac cross-sectional area (mDCSA) by MRI, Visual Analog Scale (VAS), Oswestry Disability Index (ODI), and modified MacNab outcomes were assessed. …”
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1527
Efficacy of Abatacept for Arthritis in Patients with an Overlap Syndrome between Rheumatoid Arthritis and Systemic Lupus Erythematosus
Published 2013-01-01“…Health Assessment Questionnaire-Disability Index (HAQ-DI) also significantly decreased between baseline and 24 weeks (). …”
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1528
Systematic analysis of co-expression network and gene expression profile of differentially expressed lncRNA-mRNA one week after spinal cord injury
Published 2024-12-01“…Abbreviations: SCI: spinal cord injury; CNS: central nervous system; YLDs: years of life lived with disability; lncRNAs: long noncoding RNAs; mRNAs: messenger RNAs; DE: differentially expressed; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; GSEA: gene set enrichment analysis; RIN: Renewable Identification Number; PCA: principal component analysis; PPI: protein–protein interaction; MF, molecular function; BP: biological process; CC: cellular component; MCODE: molecular complex detection…”
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1529
Prevalence of neonatal sepsis and associated factors among neonates admitted in the neonatal intensive care unit at Lira Regional Referral Hospital, Northern Uganda.
Published 2025-01-01“…An estimated 5.29-8.73 million Disability-adjusted life years (DALYs) are lost annually in SSA due to neonatal sepsis (NS). …”
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1530
Prescription of Strong Opioids in Chronic Non-Cancer Pain in the Province of Valladolid (Spain)
Published 2025-01-01“…<b>Background:</b> Chronic non-cancer pain (CNCP) is one of the leading causes of disability. The use of strong opioids (SOs) in the management of CNCP is increasing, although evidence supporting their use remains limited. …”
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1531
The Effectiveness of Acupuncture on Myofascial Trigger Points Versus Traditional Chinese Medicine Acupoints for Treating Plantar Fasciitis With Low Back Pain: A Study Protocol for...
Published 2025-01-01“…Ziling Huang,1 Xin Liang,1 Yuheng Luo,1 Zhou Fang,2 Ming Xu,1 Yinqin Xu,1 Shan Cheng,3 Lihong Li1 1Department of Acupuncture and Moxibustion, The Affiliated Hospital of Guizhou Medical University, Guizhou, People’s Republic of China; 2Department of Orthopedics, The Affiliated Hospital of Guizhou Medical University, Guizhou, People’s Republic of China; 3Ultrasound Center, The Affiliated Hospital of Guizhou Medical University, Guizhou, People’s Republic of ChinaCorrespondence: Lihong Li, Email 1109718711@qq.comBackground: Plantar fasciitis is a common cause of heel pain, often associated with a higher rate of low back pain. This increased disability rate in low back pain may be correlated with reduced foot and ankle function. …”
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1532
Impact of the Relationship between Extensor Pollicis Brevis Entrapment Test and Ultrasound Wrist Findings and Functional Outcomes in De Quervain's Disease
Published 2024-06-01“…The preoperative assessment included disability of arm, shoulder, and hand (DASH) scores and visual analog scale (VAS) pain measurements at 6 weeks, with postoperative evaluations at both 6 weeks and 6 months. …”
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1533
Negative symptoms in schizophrenia: a study in a large clinical sample of patients using a novel automated method
Published 2015-09-01“…Negative symptoms were associated with younger age, male gender and single marital status, and with increased likelihood of hospital admission (OR 1.24, 95% CI 1.10 to 1.39), longer duration of admission (β-coefficient 20.5 days, 7.6–33.5), and increased likelihood of readmission following discharge (OR 1.58, 1.28 to 1.95).Conclusions Negative symptoms were common and associated with adverse clinical outcomes, consistent with evidence that these symptoms account for much of the disability associated with schizophrenia. Natural language processing provides a means of conducting research in large representative samples of patients, using data recorded during routine clinical practice.…”
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1534
Acute Stroke in northern Portugal: outcomes and characteristics of patients in a Medical-Surgical Emergency Department
Published 2025-01-01“… Introduction: Stroke is a leading cause of morbidity and long-term disability worldwide, significantly impacting health systems and personal lives. …”
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1535
A multidisciplinary collaborative care model involving family members in the treatment of type 2 diabetes mellitus and associated diabetes distress in young and middle-aged patient...
Published 2024-01-01“…Diabetes mellitus (DM) represents a significant and enduring health concern and, due to various complications arising from inadequate management, leads to disability and mortality. The aim of this study was to examine the impact of the family-engaged multidisciplinary collaborative care (FEC) model on the management of type 2 DM (T2DM) in young and middle-aged patients, considering the presence of DM distress. …”
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1536
mHealth Intervention for Dementia Prevention through lifestyle Optimisation (MIND-PRO) in a primary care setting: protocol for a randomised controlled trial in people with low SES...
Published 2025-02-01“…Secondary outcomes include the Cardiovascular Risk Factors, Ageing and Dementia risk score and its individual risk factors, and disability, physical activity, depressive symptoms, cognitive functioning and daily distance moved.Ethics and dissemination The MIND-PRO trial is funded by the Netherlands Organisation for Health Research and Development (ZonMw, grant number 10510032120004) and approved by the Ethics Committee of Amsterdam UMC (reference: METC 2023.0770). …”
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1537
The Effect of Whole-Body Vibration on Upper Extremity Function in Children with Cerebral Palsy: A Pilot Study
Published 2025-01-01“…Cerebral palsy (CP) is the leading cause of lifelong physical disability, affecting approximately 17 million individuals worldwide. …”
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1538
Evaluation of transcriptomic changes after photobiomodulation in spinal cord injury
Published 2025-01-01“…Abstract Spinal cord injury (SCI) is a significant cause of lifelong disability, with no available disease-modifying treatments to promote neuroprotection and axon regeneration after injury. …”
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1539
Development and internal validation of the Edmonton Obesity Staging System-2 Risk screening Tool (EOSS-2 Risk Tool) for weight-related health complications: a case-control study in...
Published 2022-06-01“…Of 14 candidate risk factors, 6 (family history of diabetes, hypertension, high sugar in blood/urine, high cholesterol and self-reported bodily pain and disability) were automatically included based on definitional or obvious correlational criteria. …”
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1540
Clinical Features Associated with Frozen Shoulder Syndrome in Parkinson’s Disease
Published 2015-01-01“…Frozen shoulder syndrome is a common musculoskeletal disease of idiopathic Parkinson’s disease (PD) that causes long-term pain and physical disability. A better understanding of the associated factors can help identify PD patients who will require prevention to improve their quality of life. …”
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