Broadening the diversity of consumers engaged in guidelines: a scoping review by Sophie Hill, Tari Turner, Anneliese Synnot, Kelvin Hill, Allison Jauré, Bronwen Merner, Peta Bates, Alexandra Liacos

“…The most commonly included PROGRESS-PLUS categories were Disability, Race/culture/ethnicity/language, Place of residence and Other vulnerable (eg, ‘disadvantaged groups’). …”
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Characteristics and Management of Uncontrolled Gout Prior to Pegloticase Therapy: A 2-year Claims Analysis by Robert J. Morlock, Deepan Dalal, Victoria Divino, Mitchell DeKoven, Stephanie D. Taylor, Atsuko Powers, Naina Barretto, Robert J. Holt, Brian LaMoreaux

“…Abstract Objective Gout is a progressive form of arthritis that causes significant pain and disability. Patients with treatment-refractory (or uncontrolled) gout experience a higher prevalence and severity of comorbidities than those whose gout is controlled. …”
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Early Infantile Epileptic Encephalopathy in an STXBP1 Patient with Lactic Acidemia and Normal Mitochondrial Respiratory Chain Function by Dong Li, Elizabeth Bhoj, Elizabeth McCormick, Fengxiang Wang, James Snyder, Tiancheng Wang, Yan Zhao, Cecilia Kim, Rosetta Chiavacci, Lifeng Tian, Marni J. Falk, Hakon Hakonarson

“…A wide range of clinical findings have been associated with mutations in Syntaxin Binding Protein 1 (STXBP1), including multiple forms of epilepsy, nonsyndromic intellectual disability, and movement disorders. STXBP1 mutations have recently been associated with mitochondrial pathology, although it remains unclear if this phenotype is a part of the core feature for this gene disorder. …”
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The Efficacy of the Mulligan Concept to Treat Meniscal Pathology: A Systematic Review by Nathan C. Reep, Sydney N. Leverett, Rebecca M. Heywood, Russell T. Baker, Darren L. Barnes, Scott W. Cheatham

“…Five studies reported the Disablement in the Physically Active (DPA) scale that also demonstrated statistically significant differences or met the MCID. …”
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Modern classification and molecular-genetic aspects of osteogenesis imperfecta by A. R. Zaripova, R. I. Khusainova

“…Osteogenesis imperfecta (imperfect osteogenesis in the Russian literature) is the most common hereditary form of bone fragility, it is a genetically and clinically heterogeneous disease with a wide range of clinical severity, often leading to disability from early childhood. It is based on genetic disorders leading to a violation of the structure of bone tissue, which leads to frequent fractures, impaired growth and posture, with the development of characteristic disabling bone deformities and associated problems, including respiratory, neurological, cardiac, renal impairment, hearing loss. …”
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Early childhood constraint therapy for sensory/motor impairment in cerebral palsy: a randomised clinical trial protocol by Garey Noritz, Olena Chorna, Jill Heathcock, Alexandra Key, Helen Carey, Ellyn Hamm, Mary Ann Nelin, Micah Murray, Amy Needham, James C Slaughter, Nathalie L Maitre

“…Introduction Cerebral palsy (CP) is the most common physical disability in childhood. It is a disorder resulting from sensory and motor impairments due to perinatal brain injury, with lifetime consequences that range from poor adaptive and social function to communication and emotional disturbances. …”
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Persistence with Early-Line Abatacept versus Tumor Necrosis Factor-Inhibitors for Rheumatoid Arthritis Complicated by Poor Prognostic Factors by Xue Han, Francis Lobo, Michael S. Broder, Eunice Chang, Sarah N. Gibbs, David J. Ridley, Irina Yermilov

“…**Background:** Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint swelling and destruction that leads to severe disability. There are no clear guidelines regarding the order of therapies. …”
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Genetic polymorphisms and related risk factors of ischemic stroke in a Mongolian population in China by Q. Wu, H. Wu, Yu. L. Orlov, G. Gegentana, W. Huo, A. O. Bragin, N. Wu, S. Suyalatu, F. Zhao, J. Zhao, L. E. Tabikhanova, M. Chen, H. Bai

“…Ischemic stroke is caused by an interruption in the flow of blood to the brain and a risk factor for death and disability. Recent genome-wide association studies have identified more than 40 common sequence variants associated with ischemic stroke. …”
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Enhancing individual task performance and productivity: an ethnographic observational study of supported employment among social services clients in Finland by Pirjo Juvonen-Posti, Mirkka Vuorento

“…Results The main findings were that persons with disability or decreased work ability were employed in precarious low-productivity work, with limited opportunities for more sustainable employment. …”
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Individual and joint effects of exposure to multiple organophosphate esters and the risk of depression in adults: Differences in sex, age, and physical activity by Qingmiao Wei, Jiyun Wei, Jun Liang

“…Depression, a severe mental disorder, is a prominent cause of global disability and worldwide. Organophosphate esters (OPEs) are neuron-disrupting chemicals that potentially cause depression. …”
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Long-Term Health-Related Quality of Life in Kawasaki Disease-Related Coronary Artery Aneurysm: A Large Single-Center Assessment in Nanjing, China by Yun Zhou, MD, Mei Chen, MD, Wenting Gao, MD, Yu Chen, MD, Ying Meng, MD

“…Routine outpatient HRQOL screening could be instituted to help eliminate the risk of long-term disability following initial clinical improvement.…”
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Effect of Repeated Remote Ischemic Preconditioning on Peripheral Arterial Disease in Patients Suffering from Intermittent Claudication by Mehmet Balin, Tarık Kıvrak

“…Intermittent claudication (IC) is the symptom of peripheral artery disease (PAD) and causes functional disability. Remote ischemic preconditioning (RIPC), is a phenomenon in which a short period of sub-critical ischemia, protects tissues against ischemia/reperfusion/injury. …”
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Efficacy of High-Dose and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcomes in Patient with Acute Ischemic Stroke: A Randomized, Double-Blind, Parallel, C... by Nattaphol Uransilp, Pannawat Chaiyawatthanananthn, Sombat Muengtaweepongsa

“…Stroke is the leading cause of death and long-term disability. Oxidative stress is elevated during occurrence of acute ischemic stroke (AIS). …”
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The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with age-related hearing impairment in a Taiwanese population: a case control study by Ning-Chia Chang, Hua-Ling Yang, Chia-Yen Dai, Wen-Yi Lin, Hsun-Mo Wang, Chen-Yu Chien, Kuen-Yao Ho

“…Abstract Background Age-related hearing impairment (ARHI) is a major disability among the elder population. Chronic inflammation is an important factor in the development of ARHI. …”
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A comparison of kinesiophobia, pain-activity patterns and fear-avoidance beliefs in patients with chronic low back pain by Egemen Kızılay, Fatma Kızılay, Betül Ergün

“…According to fear - avoidance models, kinesiophobia is related to pain severity and disability. Kinesiophobia is a psychological factor that attracts attention in people with persistent pain, is related to the severity and persistence of pain. …”
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Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury by Duraisamy Kempuraj, Mohammad Ejaz Ahmed, Govindhasamy Pushpavathi Selvakumar, Ramasamy Thangavel, Sudhanshu P. Raikwar, Smita A. Zaheer, Shankar S. Iyer, Casey Burton, Donald James, Asgar Zaheer

“…Traumatic brain injury (TBI) is one of the major health problems worldwide that causes death or permanent disability through primary and secondary damages in the brain. …”
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Multicenter Randomized Clinical Trial of Brief Psychotherapy versus Usual Treatment for Common Mental Disorders in Adults by Marco A. Luengo-Castro, Javier Fernández-Méndez, José M. García-Montes, Pedro J. Caunedo-Riesco, Juan M. García-Haro, Begoña Braña-Menéndez, Dolores González-Díaz, Andrés Cabero-Álvarez, Marcelino Cuesta-Izquierdo

“…Pre-treatment and up to 3-year assessments were conducted on clinical-administrative, symptomatic, disability, satisfaction, and psychopharmacological consumption. …”
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Idiopathic Central Precocious Puberty Associated with 11 Mb De Novo Distal Deletion of the Chromosome 9 Short Arm by Mariangela Cisternino, Erika Della Mina, Laura Losa, Alexandra Madè, Giulia Rossetti, Lorenzo Andrea Bassi, Giovanni Pieri, Baran Bayindir, Jole Messa, Orsetta Zuffardi, Roberto Ciccone

“…We report a girl with a de novo distal deletion of 9p affected by idiopathic central precocious puberty and intellectual disability. Genome-wide array-CGH revealed a terminal deletion of about 11 Mb, allowing to define her karyotype as 46; XX, del(9)(p23-pter). …”
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The emerging role of glycine receptor α2 subunit defects in neurodevelopmental disorders by Sean D. Fraser, Sean D. Fraser, Robert J. Harvey, Robert J. Harvey

“…Consistent with these findings, we and others have identified missense variants and microdeletions in the human GlyR α2 subunit gene (GLRA2) in individuals with autism spectrum disorder (ASD), developmental delay (DD) and/or intellectual disability (ID), often accompanied by microcephaly, language delay and epilepsy. …”
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Students’ Perspectives on Learning Practical Nursing Skills: A Focus Group Study in Norway by A. G. Gregersen, M. T. Hansen, S. E. A. Brynhildsen, V. A. Grøndahl, A. C. Leonardsen

“…Three focus group interviews were conducted with registered nurse students and intellectual disability nurse students in their last semester (n = 11). …”
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