Awareness and attitudes of pregnant women concerning genetic disorders and pregnancy termination in northeastern Iran by Nafiseh Todarbary, Abouzar Irandegani, Mojtaba Meshkat, Aida Gholoobi, Tayebeh Hamzehloei

“…Additionally, the number of children was correlated with congenital blindness, Duchenne muscular dystrophy, autism, Proteus syndrome, Klinefelter syndrome, anencephaly, mental retardation (MR), quadriplegia, and severe learning disability and mental health (LDMH). Age was associated with conditions such as epilepsy, congenital blindness, schizophrenia, and severe LDMH. …”
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Disease Burden and Harm of Osteoarthritis by WU Haotian, LIN Jianhao

“…In 2019, approximately 530 million people suffered from osteoarthritis, with the age-standardized incidence rate of 492.2 per 100 000, the age-standardized prevalence rate of 6348.3 per 100 000 and the age-standardized rate of disability-adjusted life years (DALYs) of 228.0 per 100 000. …”
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Effect of Intra-Articular Hyaluronic Injection on Postural Stability and Risk of Fall in Patients with Bilateral Knee Osteoarthritis by Nafiseh Khalaj, Noor Azuan Abu Osman, Abdul Halim Mokhtar, John George, Wan Abu Bakar Wan Abas

“…Knee osteoarthritis is a common cause of disability which influences the quality of life. It is associated with impaired knee joint proprioception, which affects postural stability. …”
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Clinical Report of a 17q12 Microdeletion with Additionally Unreported Clinical Features by Jennifer L. Roberts, Stephanie K. Gandomi, Melissa Parra, Ira Lu, Chia-Ling Gau, Majed Dasouki, Merlin G. Butler

“…We present a tall-appearing 17-year-old boy with marfanoid habitus, hypermobile joints, mild scoliosis, pectus deformity, widely spaced nipples, pes cavus, autism spectrum disorder, intellectual disability, and psychiatric manifestations including physical and verbal aggression, obsessive-compulsive behaviors, and oppositional defiance. …”
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Biomaterial Applications in Cell-Based Therapy in Experimental Stroke by Ligia S. B. Boisserand, Tomonobu Kodama, Jérémie Papassin, Rachel Auzely, Anaïck Moisan, Claire Rome, Olivier Detante

“…Stroke is an important health issue corresponding to the second cause of mortality and first cause of severe disability with no effective treatments after the first hours of onset. …”
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The Effect of a Turkey Berry (Solanum torvum)-Fortified Biscuit on the Hemoglobin Level and Cognitive Performance of Adolescent Females in the Ahafo Region of Ghana: A Pilot Study by Abigail Owusuaa Appiah, Marina Aferiba Tandoh, Pepertual Suglo Puotege, Anthony Kwaku Edusei

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Satisfactory Functional Outcome and Significant Correlation with the Length of Haglund’s Deformity after Endoscopic Calcaneoplasty: A Minimum 4-Year Follow-Up Study by Hossam Fathi Mahmoud, Walid Feisal, Fahmy Samir Fahmy

“…Haglund’s syndrome is a posterosuperior calcaneal prominence with posterior heel pain causing functional disability to the patient. Operative treatment is indicated after failure of conservative measures and includes resection of the bony hump along with retrocalcaneal bursectomy. …”
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Off-Label Use of Intravenous Immunoglobulin with Methylprednisolone to Treat Parsonage–Turner Syndrome in a United States Marine by Carissa M. Sedlacek, Michael Leone, Adam D. Foster, Amy Hinkelman

“…Full functional recovery can take months to years, but recurrence and/or persistence of symptoms and disability are frequent. This case reports a 22-year-old male who recovered from NA within 3 months following treatment with 1000 mg of methylprednisolone and off-label use of 0.5 g/kg of intravenous immunoglobulins (IVIG) for four consecutive days. …”
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Characteristic craniofacial defects associated with a novel USP9X truncation mutation by Namiki Nagata, Hiroshi Kurosaka, Kotaro Higashi, Masaya Yamaguchi, Sayuri Yamamoto, Toshihiro Inubushi, Miho Nagata, Yasuki Ishihara, Ayumi Yonei, Yohei Miyashita, Yoshihiro Asano, Norio Sakai, Yasushi Sakata, Shigetada Kawabata, Takashi Yamashiro

“…Here, we report a Japanese girl with a novel heterozygous nonsense mutation in USP9X who exhibited intellectual disability with characteristic craniofacial abnormalities, including hypotelorism, brachycephaly, hypodontia, micrognathia, severe dental crowding, and an isolated submucous cleft palate. …”
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Enhancing Plasticity of the Central Nervous System: Drugs, Stem Cell Therapy, and Neuro-Implants by Alice Le Friec, Anne-Sophie Salabert, Carole Davoust, Boris Demain, Christophe Vieu, Laurence Vaysse, Pierre Payoux, Isabelle Loubinoux

“…Stroke represents the first cause of adult acquired disability. Spontaneous recovery, dependent on endogenous neurogenesis, allows for limited recovery in 50% of patients who remain functionally dependent despite physiotherapy. …”
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ADATs: roles in tRNA editing and relevance to disease by Mao Xue-Ling, Eriani Gilbert, Zhou Xiao-Long

“…This review provides detailed information on A-to-I and C-to-U editing of tRNAs in different domains of life, presents recent new findings on ADATs for DNA editing, and finally comments on the association of mutations in the ADAT3 gene with intellectual disability.…”
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Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain by Han-Chung Lee, Kai-Leng Tan, Pike-See Cheah, King-Hwa Ling

“…Trisomy of human chromosome 21 in Down syndrome (DS) leads to several phenotypes, such as mild-to-severe intellectual disability, hypotonia, and craniofacial dysmorphisms. …”
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Osteoarthritis-related knee pain: MRI-guided focused ultrasound ablation treatment by Christin A. Tiegs-Heiden, Zaiyang Long, Aiming Lu, Krzysztof R. Gorny, Gina K. Hesley

“…Objective: Osteoarthritis of the knee is a common cause of pain, functional disability, and reduced quality of life in the elderly. …”
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Botox (OnabotulinumtoxinA) for Treatment of Migraine Symptoms: A Systematic Review by Negar Shaterian, Negin Shaterian, Aref Ghanaatpisheh, Farnaz Abbasi, Sara Daniali, Maryam Jalali Jahromi, Mohammad Sadegh Sanie, Amir Abdoli

“…The use of BoNT-A in individuals suffering from chronic migraine (CM) decreases the frequency of migraine attacks per month, pain intensity, medication use, emergency visits, and migraine-related disabilities. The BoNT-A was well tolerated and leads to improved performance and better quality of life (QoL). …”
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Mental health morbidities in Kerala, India: Insights from National Mental Health Survey, 2015–2016 by Sonakshi Jyrwa, T. M. Shibukumar, Jayakrishnan Thavody, P. K. Anish, Thomas Bina, K.R. Rajith, Pradeep S. Banandur, Girish N. Rao, Gopalkrishna Gururaj, Mathew Varghese, Vivek Benegal

“…The instruments used in the survey included M.I.N.I adult version 6.0, a modified version of the Fagerström Nicotine Dependence Scale and questionnaires to screen for epilepsy, intellectual disability, and autism spectrum disorders. Results: A total of 2479 respondents aged >18 years were interviewed. …”
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Determination of damaging SNP’s in SHANK3 gene with in silico methods by İrem Gülfem Albayrak, Şeyma Yektar, Süeda Kaya

“…The SHANK3 gene has a significant role in autism spectrum disorder; mutations in this gene are seen in roughly 1–2% of patients with both autism and intellectual disability. This genetic association provides insight concerning SHANK3's potential significance in the disorder's development. …”
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Socioeconomic status and left ventricular ejection fraction decline in breast cancer survivors following receipt of doxorubicin (PREVENT WF-98213) by Arnethea L. Sutton, Nathaniel S. O’Connell, Alexander R. Lucas, Kristine C. Olson, Kerryn W. Reding, Vanessa B. Sheppard, Bonnie Ky, Kathryn J. Ruddy, Kathryn E. Weaver, W. Gregory Hundley

“…However, six months following treatment, survivors who were unemployed for reasons other than retirement and disability experienced greater LVEF declines compared to survivors who were employed ((b = 2.79 [95% confidence interval (CI): 0.37–5.20; p = 0.026). …”
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The Association between Serum Bilirubin Level and Electrochemical Skin Conductance in Chinese Patients with Type 2 Diabetes by Fei Mao, Xiaoming Zhu, Bin Lu, Yiming Li

“…Both SUDOSCAN and other traditional diabetic neuropathy examinations including neuropathy symptom score (NSS), the neuropathy disability score (NDS) and Michigan Neuropathy Screening Instrument (MNSI) scores were performed in all patients with T2DM. …”
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Characteristics and Outcomes of Shared Bicycle-Related Injuries from a Large Emergency Medical Centre in China, 2017–2021 by Mao Chen, Weiwei Li, Jun Ye, Gang Liu, Chaolin Huang

“…The fatality rate was 9.53%, 72.24% of victims recovered well without permanent disability, and 18.23% of victims had permanent disabilities. …”
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Exerkines and Sarcopenia: Unveiling the Mechanism Behind Exercise-Induced Mitochondrial Homeostasis by Jiayin Wang, Dandan Jia, Zhiwang Zhang, Dan Wang

“…<b>Background/Objectives</b>: Sarcopenia, characterized by the progressive loss of muscle mass and strength, is linked to physical disability, metabolic dysfunction, and an increased risk of mortality. …”
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