The Role of Thoracic Medial Branch Blocks in Managing Chronic Mid and Upper Back Pain: A Randomized, Double-Blind, Active-Control Trial with a 2-Year Followup by Laxmaiah Manchikanti, Vijay Singh, Frank J. E. Falco, Kimberly A. Cash, Vidyasagar Pampati, Bert Fellows

“…Outcome measures included the numeric rating scale (NRS), Oswestry Disability Index (ODI), opioid intake, and work status, at baseline, 3, 6, 12, 18, and 24 months. …”
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Physical activity and ageing: The role of physiotherapy in promoting healthy ageing by Shane Naidoo, Nirmala Naidoo

“…Background: The global rise in the older population, especially in sub-Saharan Africa, has heightened the impact of non-communicable diseases (NCDs), responsible for 74% of global deaths and the leading cause for years lived with disability. Physical activity (PA) has proven to manage NCDs; however, 80% of older adults in sub-Saharan Africa engage in low-to-moderate PA levels. …”
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Social Attitudes toward Cerebral Palsy and Potential Uses in Medical Education Based on the Analysis of Motion Pictures by Marek Jóźwiak, Brian Po-Jung Chen, Bartosz Musielak, Jacek Fabiszak, Andrzej Grzegorzewski

“…With the criteria of nondocumentary movies, possibility of disability classification, and availability, the total number of motion pictures about CP was reduced to 34. …”
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A Case of Neuromyelitis Optica: Puerto Rican Woman with an Increased Time Lag to Diagnosis and a High Response to Eculizumab Therapy by Ramón Vega, Benjamín González, Kiara Ortiz, Viviana Martínez, David Carmona, Ivonne Vicente, Javier Chapa, Ángel Chinea

“…In addition, the patient suffered no new relapses, an improvement regarding disability, and a reduction of the cervical spinal cord lesion size. …”
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IL-17 and IL-22 in Cerebrospinal Fluid and Plasma Are Elevated in Guillain-Barré Syndrome by Shujuan Li, Ming Yu, Haifeng Li, Hongliang Zhang, Yanfang Jiang

“…IL-17 and IL-22 levels in CSF, respectively, are correlated with GBS disability scale scores (GDSs). Meanwhile, IL-17 and IL-22 levels in CSF, IL-22 in CSF, and plasma of GBS patients have positive correlation, respectively. …”
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Risk factors burden in Cuba, Latin American and the Caribbean region by Armando Seuc Jo, Mayelin Mirabal Sosa, Yanet García Serrano, Karen Alfonso Sague, Oscar Díaz Díaz, Delia María Gálvez Medina

“…<br /><strong>Methods:</strong> descriptive research, in which, using data from the Global Health Data Exchange platform, Institute of Health Metrics and Evaluation (GHDx-IHME), the percentages of risk factors were calculated within each of the locations and for each of the metrics, particularly disability-adjusted life years, to facilitate the identification of priorities.…”
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Brain-Derived Neurotrophic Factor Polymorphism and Aphasia after Stroke by Nathan T. Lee, Fatimah Ahmedy, Natiara Mohamad Hashim, Khin Nyein Yin, Kai Ling Chin

“…Stroke is one of the most deliberating causes of mortality and disability worldwide. Studies have implicated Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene as a genetic factor influencing stroke recovery. …”
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Effect of Russian Current in Motor Performance among Chronic Stroke Survivors: A Pilot Study by Joshin Joy, Hariharasudhan Ravichandran, Noble Vavachan, Adwaid Nambiar, Archana Shetty, Joseph Oliver Raj Alexander

“…Background and Aim: Stroke is a leading cause of permanent disability in developing nations. Motor impairment in stroke contributes to limitations in activities of daily life, participation in community, and overall quality of life. …”
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Advancing Obsessive–Compulsive Disorder Research: Insights from Transgenic Animal Models and Innovative Therapies by Xinyuejia Huang, Linglong Xiao, Mengqi Wang, Yang Wu, Hao Deng, Wei Wang

“…Obsessive–compulsive disorder (OCD) is a prevalent, chronic, and severe neuropsychiatric disorder that leads to illness-related disability. Despite the availability of several treatments, many OCD patients respond inadequately, because the underlying neural mechanisms remain unclear, necessitating the establishment of many animal models, particularly mouse models, to elucidate disease mechanisms and therapeutic strategies better. …”
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Ciprofloxacin and Clozapine: A Potentially Fatal but Underappreciated Interaction by Jonathan M. Meyer, George Proctor, Michael A. Cummings, Laura J. Dardashti, Stephen M. Stahl

“…We report the case of a 28-year-old nonsmoking female with intellectual disability who was maintained for 3 years on clozapine 100 mg orally twice daily. …”
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Reduction in Healthcare Resource Utilization Following Treatment With a Home-Based Footworn Device in Patients With Knee Osteoarthritis: A Retrospective Claims Analysis by Josh Mark, Shirley Shema-Shiratzky, Joel Sommer, Tim Nolan, Ganit Segal

“…OA is the third most rapidly rising condition associated with disability and leads to a significant burden on the healthcare system and society. …”
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Low Urbanization but Not Illiteracy was Associated with Poor Medication Adherence among Elderly People in Rural Taiwan by Pei-Jhih Li, Ling-Chiao Liao, Chin-Ju Chuang, Cheng-Ying Hsieh, Yung-Cheng Huang, Li-Yu Chen, Yi-Hsuan Yang, Feng-Jung Yang, Kai-Chieh Chang, Li-Jiuan Shen, Fei-Yuan Hsiao, Yen-Ming Huang, Chih-Cheng Hsu, Shau-Huai Fu, Chin-Kai Chang, Chen-Yu Wang

“…Future research is warranted to assess the effect of the interventions to improve medication adherence on chronic disease control, disability, and mortality.…”
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Effectiveness of Mobilization with Movement on the Management of Knee Osteoarthritis: A Systematic Review of Randomized Controlled Trials by Gidey Gomera Weleslassie, Melaku Hailu Temesgen, Abayneh Alamer, Gebrerufael Solomon Tsegay, Teklehaimanot Tekle Hailemariam, Haimanot Melese

“…Osteoarthritis is becoming a global major cause of pain and functional disability worldwide, especially in the elderly population. …”
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Prospective Single-Site Experience with Radiofrequency-Targeted Vertebral Augmentation for Osteoporotic Vertebral Compression Fracture by Franklin G. Moser, Marcel M. Maya, Laura Blaszkiewicz, Andrea Scicli, Larry E. Miller, Jon E. Block

“…We report our initial experience with radiofrequency-targeted vertebral augmentation (RF-TVA) in 20 patients aged 50 to 90 years with single-level, symptomatic osteoporotic VCF between T10 and L5, back pain severity > 4 on a 0 to 10 scale, Oswestry Disability Index ≥ 21%, 20% to 90% vertebral height loss compared to adjacent vertebral body, and fracture age < 6 months. …”
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Using Facebook to tell stories of premature ageing and sexual and reproductive healthcare across the life course for women with cerebral palsy in the UK and USA by Julie Taylor, Sonali Shah, C Bradbury-Jones

“…Objective To enhance understanding of the bodily and lifestyle effects of ageing with cerebral palsy (CP) for women, with a particular focus on experiences with sexual and reproductive healthcare (SRH) services in the UK and North America.Design A qualitative study underpinned by feminist disability theory and drawing on digital ethnographies to capture health and healthcare experiences for women with CP.Setting A global community of 140 women with CP, who are members of the closed international Facebook group, Women Ageing with Cerebral Palsy (WACP).Participants Forty-five members of WACP who were based in the UK and North America. …”
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Burden of Coronary Artery Disease and Peripheral Artery Disease: A Literature Review by Rupert Bauersachs, Uwe Zeymer, Jean-Baptiste Brière, Caroline Marre, Kevin Bowrin, Maria Huelsebeck

“…Survival rates have improved with medical advancements, but there is an additional need to improve the humanistic burden of disease (i.e., associated disability and quality of life). The economic burden of atherothrombotic disease is high and expected to increase with increased survival and the aging population. …”
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Frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawar by Abdul Ahad, Romana Bibi, Sijad Ur Rehman, Majid Ali Shah, Matea Ullah, Shahinda

“…Severe neonatal jaundice and its progression to kernicterus is a leading cause of death and disability among newborns in poorly-resourced countries. …”
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Tissue Engineered Strategies for Skeletal Muscle Injury by Umile Giuseppe Longo, Mattia Loppini, Alessandra Berton, Filippo Spiezia, Nicola Maffulli, Vincenzo Denaro

“…Skeletal muscle injuries are common in athletes, occurring with direct and indirect mechanisms and marked residual effects, such as severe long-term pain and physical disability. Current therapy consists of conservative management including RICE protocol (rest, ice, compression, and elevation), nonsteroidal anti-inflammatory drugs, and intramuscular corticosteroids. …”
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Clinical and Radiological Outcomes of Extracorporeal Shock Wave Therapy in Early-Stage Femoral Head Osteonecrosis by Abdulrahman D. Algarni, Hassan M. Al Moallem

“…Femoral head osteonecrosis is a progressive clinical condition with significant morbidity and long-term disability. Several treatment modalities including both surgical and nonsurgical options have been used with variable levels of success. …”
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The Public Health Surveillance Well-Being Scale: Reliability and validity study of the Turkish version by Selma Infal Kesim, Fatih Kara

“…This questionnaire could be used by researchers for further investigation in different regions of Turkey, on larger sample groups and for evaluation of special groups, such as individuals with chronic illness and disability, or individuals employed in specific occupation (e.g., healthcare and social care professionals, unemployed, and students).…”