Spinal pain prevalence and associated determinants: A population‐based study using the National Survey for Wales by David C. Byfield, Benjamin S. Stacey, Hywel T. Evans, Ian W. Farr, Leon Yandle, Lora Roberts, Teresa Filipponi, Damian M. Bailey

“…Abstract Spinal pain (SP) remains the leading cause of disability worldwide. The present study aimed to establish a current prevalence of SP and associated determinants in Wales by retrospectively analyzing data from the National Survey for Wales Dataset (NSWD). …”
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The IVIG treatment response in autoimmune polyendocrine syndromes type 2 with anti-GAD65 antibody-associated stiff person syndrome: a case report and literature review by Yulong Yang, Hailin Jiang, Wenming Yang, Wenming Yang, Wenming Yang, Han Wang, Han Wang, Meixia Wang, Meixia Wang, Xiang Li, Peng Huang, Shuzhen Fang, Wenjie Hao, Yue Yang, Furong Zhao, Wei He

“…Most practicing neurologists encounter only one or two cases of APS-2 combined with anti-GAD65 antibody-associated SPS in their careers, resulting in underdiagnosis and undertreatment, leading to severe disability and suffering. This case report describes a young male who initially exhibited hair loss, vitiligo, and previously unreported eosinophilia. …”
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Intersectional discrimination, exclusion and the socio-political economy of global mental health: A systematic scoping review of the literature by Rochelle A. Burgess, Sorcha Ní Chobhthaigh, Bijayalaxmi Biswal, Diana Ceccolini, Babatunde Fadipe, Denaneer Khan, Neena Aggarwal, Ishrat Pabla, Camila Solis, Ramya Pillutla, Piyali Sarkar, Eric Frasco, Valentina lemmi, Soumitra Pathare, Crick Lund

“…In this scoping review, we explore the extent to which the current mental health evidence base acknowledges the impact of intersectional structural determinants of mental health outcomes, via the mechanism of discrimination - linked to a range of commonly underexplored socio-political factors (Protocol registration DOI:10.17605/OSF.IO/CGJQH).We included nine social phenomena widely acknowledged in social theory as contributing to the patterning of social determinants: (1) Political Dynamics, (2) Racism, Caste & Xenophobia, (3) Gender & Sexuality, (4) Neighbourhood Dynamics, (5) Class & Working conditions, (6) Colonialism, (7) Indigeneity, (8) Religious & Spiritual Identities (9) Age & Disability. We explored these factors intersectionally, including studies with two or more factors in their analyses. …”
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Cost-effectiveness of decentralising acute malnutrition treatment with a standard or simplified treatment protocol: an economic evaluation in the region of Gao, Mali by Bernardette Cichon, Noemí López-Ejeda, Salimata Samake, Cornelia Aton, Abdias Ogobara Dougnon, Mahamadou N’tji Samake, Aliou Bagayoko, Magloire Bunkembo, Alexandra Rutishauser-Perera, Pilar Charle-Cuellar

“…Outcomes assessed were cost per child treated as well as average and incremental cost-effectiveness ratios for cost per child cured and disability adjusted life year (DALY) averted. A within study trial horizon, from March 2020 to July 2021, was used. …”
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Modelling the potential clinical and economic impact of universal antenatal hepatitis C (HCV) screening and providing treatment for pregnant women with HCV and their infants in Egy... by Giuseppe Indolfi, Diana M Gibb, Aya Mostafa, Sarah Pett, Yazdan Yazdanpanah, Sylvie Deuffic-Burban, Anthony E Ades, Karen Scott, Ali Judd, Nadia Hachicha-Maalej, Clotilde Lepers, Intira Jeannie Collins, Manal H El Sayed

“…Discounted lifetime cost, life expectancy (LE) and disability-adjusted life-years (DALYs) were calculated separately for women and their infants, and then combined.Results Current practice led to the highest cost (US$314.0), the lowest LE (46.3348 years) and the highest DALYs (0.0512 years) per mother–child pair. …”
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Trends and future predictions of chronic kidney disease due to diabetes mellitus type 2 attributable to dietary risks: insights based on GBD 2021 data by Ming Xu, Ming Xu, Hongxia Wei, Hongxia Wei, Dongqing Lv, Dongqing Lv, Yanhong Wei, Yanhong Wei, Ziang Liu, Ziang Liu, Yi Zhang, Yi Zhang, Yunfeng Liu, Yunfeng Liu, Yunfeng Liu

“…This study examines the influence of dietary risk factors across various populations and socioeconomic groups.MethodsUtilizing the 2021 GBD data, we analyzed age-standardized CKD-T2DM metrics—including mortality, disability-adjusted life years (DALY), and age-standardized rates (ASR)—stratified by age, gender, and region. …”
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Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021 by Qi Zhang, Lan Luo, Lai-lai Yan, Lai-lai Yan, Jing Guo, Hui-jun Wu, Zi-wei Zhang, Yu-hua Zhu, Rui Qiao, Rui Qiao

“…Trends and influencing factors were investigated through Joinpoint regression, health inequality analysis, and frontier modeling.ResultsIn 2021, the global age-standardized mortality rate (ASMR) and age-standardized disability-adjusted life year (DALY) rate (ASDR) for neonatal diseases associated with low birth weight (LBW) were 22.76 [95% uncertainty interval (UI): 19.63–26.40] and 2,227.54 (95% UI: 1,939.96–2,563.52) per 100,000, respectively. …”
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Clinical Efficacy of Muscle Energy Technology Combined with Conventional Rehabilitation Therapy on Patients with Chronic Non-Specific Neck Pain by ZHENG Kun, YANG Haolun, JIA Chengsen, ZHANG Liming

“…Before treatment and one week after treatment, visual analog scale (VAS) was used to assess the pain level; neck disability index (NDI) was used to evaluate cervical spine dysfunction; Yasuhisa Tanaka cervical spondylotic radiculopathy 20 (CSR20) was used to evaluate cervical spine function; "Clinical practice guideline for physical therapy assessment and treatment in patients with nonspecific neck pain" were used to evaluate the clinical efficacy; the adverse reaction such as aggravation of neck pain, nausea, vomiting, dizziness, increased heart rate, etc. that occurred during treatment were observed.ResultsCompared with that before treatment, VAS scores and NDI index decreased significantly of both groups after treatment (<italic>P</italic>&lt;0.05), CSR20 score increased significantly, and the differences were statistically significant (<italic>P</italic>&lt;0.05). …”
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<i>MECP2</i> Duplication Syndrome: AI-Based Diagnosis, Severity Scale Development and Correlation with Clinical and Molecular Variables by Lourdes Vega-Hanna, Dídac Casas-Alba, Sol Balsells, Mercè Bolasell, Patricia Rubio, Ana García-García, Oscar García-García, Mar O’Callaghan, Ainhoa Pascual-Alonso, Judith Armstrong, MDS Group, Antonio F. Martinez-Monseny

“…Key features in males comprised intellectual disability (100%), hypotonia (93%), autism spectrum disorder (77%) and developmental regression (52%). …”
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Healthcare performance of leprosy management in peripheral health facilities of Dhanusa and Mahottari, Nepal by Ram Kumar Mahato, Uttam Ghimire, Bijay Bajracharya, Binod K. C., Deepak Bam, Deepak Ghimire, Uttam Raj Pyakurel, David T. S. Hayman, Basu Dev Pandey, Chuman Lal Das, Krishna Prasad Paudel

“…All identified cases (n = 187) adhered to the complete treatment and release after treatment (RFT) scheme, out of which 84.5% were satisfied with the service they were provided. Leprosy disability and ear hand and feet (EHF) scores were not significantly reduced in treated patients during the study period, but counseling by LFPs significantly improved cases’ positive beliefs and practices regarding self-care. …”
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Collagenase Chemonucleolysis for Treating Cervical Disc Herniation: An Exploratory, Single-Arm, Open-Label, Multicenter Clinical Trial by Zhijian Wang, Bifa Fan, Lili Gu, Xuexue Zhang, Tao Sun, Hui Liu, Rongchun Li, Likui Wang, Kaiqiang Wang, Shun Li, Yong Ma, Haibo You, Daying Zhang

“…The secondary efficacy endpoints were the percentage reduction in Numeric Rating Scale (NRS) and Neck Disability Index (NDI) scores from baseline, which were not lower than the reference values (≥ 40%, ≥ 30%), and improvement in the 36-Item Short Form Health Survey (SF-36) score compared to the preoperative value. …”
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Ambient air pollution and Alzheimer’s disease and other dementias: a global study between 1990 and 2019 by Cui Guo, Dongze Wu, Jun Yang, Xingcheng Lu, Xiang Yan Chen, Jun Ma, Changqing Lin, Alexis K. H. Lau, Yingzhao Jin, Ruiyun Li, Shenjing He

“…These data include age-standardised mortality rate (ASMR) and disability-adjusted life-years (DALYs) of AD and other dementias, ambient air pollution (fine particulate matter [PM2.5], NO2 and O3 concentration) and a series of covariates were from various source. …”
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Changing patterns of cardiovascular diseases and subtypes induced by kidney dysfunction among 25–64 years in China from 1992 to 2021 by Guoqiang Zeng, Hongliang Wang, Pinghui Cao, Jinyang Zhao, Lingyun Liu, Hui Guo

“…Methods This study extracted data from the Global Burden of Disease (GBD) 2021, focusing on deaths and disability-adjusted life years (DALYs) caused by KD-induced CVD and subtypes, including ischemic heart disease (IHD), stroke, and lower extremity peripheral artery disease (LEPAD) among 25–64 years globally and in China from 1992 to 2021. …”
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Increasing Dose of Autologous Bone Marrow Mononuclear Cells Transplantation Is Related to Stroke Outcome: Results from a Pooled Analysis of Two Clinical Trials by Francisco Moniche, Paulo Henrique Rosado-de-Castro, Irene Escudero, Elena Zapata, Francisco Javier de la Torre Laviana, Rosalia Mendez-Otero, Magdalena Carmona, Pilar Piñero, Alejandro Bustamante, Lucía Lebrato, Juan Antonio Cabezas, Alejandro Gonzalez, Grabriel R. de Freitas, Joan Montaner

“…In the intra-arterially treated patients, a strong correlation between dose of cells and disability was found (r=-0.63, p=0.006). A cut point of 310 × 106 injected cells predicted good outcome with 80% sensitivity and 88.2% specificity. …”
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Clinical features of early multiple sclerosis by I. Čelpačenko, R. Stankevičiūtė, M. Malciūtė, R. Balnytė

“…Delayed treatment increases the risk of disability, therefore, establishing a clear phenotype of early MS can help in a more efficient diagnostic process. …”
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Global, regional and national burden of neuroblastoma and other peripheral nervous system tumors, 1990 to 2021 and predictions to 2035: visualizing epidemiological characteristics... by Chaoyan Yue, Qi Zhang, Fenyong Sun, Qiuhui Pan

“…Methods: Based on the GBD 2021 database, this study analyzed the incidence, mortality, prevalence, and Disability-Adjusted Life-Years (DALYs) of neuroblastoma and other peripheral nervous system tumors from 1990 to 2021, stratified by sociodemographic development index (SDI) and geographic regions. …”
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Risk factors affecting progression and course of primary open-angle glaucoma in patients with different disease stages (multicenter study) by N.E. Fomin, P.Ch. Zavadskiy, A.V. Kuroyedov, A.V. Seleznev, Z.M. Nagornova, D.A. Baryshnikova, R.V. Avdeev, A.M. Getmanova, I.A. Glushnev, A.A. Gusarevich, D.A. Dorofeev, S.V. Kosmynina, O.S. Myakonkaya, N.A. Rebenok, Yu.I. Razhko, I.I. Semenova, T.V. Chernyakova

“…Moreover, PEX, PDS, DED, CHD, prior myocardial infarction, and disability resulting from a general illness are additional factors determining POAG resistance to treatment.…”
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The association between neighborhood social vulnerability and community-based rehabilitation after stroke by Shuqi Zhang, Elizabeth R. Mormer, Anna M. Johnson, Cheryl D. Bushnell, Pamela W. Duncan, Fang Wen, Shweta Pathak, Amy M. Pastva, Janet K. Freburger, Sara B. Jones Berkeley

“…Greater vulnerability in household composition and disability was modestly associated with -0.4% (95% CI -4.1% to 3.4%) to -4.3% (95% CI -0.8% to -7.7%) lower rehabilitation use across SVI quartiles. …”
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Exploration of neurometabolic alterations in adolescent patients with bipolar depression and non-suicidal self-injury based on proton magnetic resonance spectroscopy by Chengji Wang, Yuan Qu, Xiaoqin Shen, Xiaoxiao Tang, Xiaoxiao Tang, Gaiyu Tong, Meier Wati, Manzeremu Naibi, Manzeremu Naibi, Cheng Zhang, Shaohong Zou

“…Its identification and diagnosis are challenging, and it is characterized by a high rate of misdiagnosis and disability. Studies have revealed that patients with ABD are more prone to non-suicidal self-injury (NSSI) compared to those with unipolar depression. …”
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Dynamics of epidemiological indicators of glaucoma in the Republic of Bashkortostan for the period of 2010–2016 by M.M. Bikbov, A.E. Babushkin, I.I. Khusnitdinov, L. Kh. Murova, E.N. Matyukhina

“…<br> <br> <b>Key words:</b> glaucoma, Republic of Bashkortostan, epidemiological indicators, primary open-angle glaucoma, prevalence, morbidity, primary disability.<br> <b>For citation:</b> Bikbov M.M., Babushkin A.E., Khusnitdinov I.I. et al. …”
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