SECTM1 acts as an immune-related biomarker of poor prognosis and promotes cancer progression by modulating M2 macrophage polarization in esophageal squamous cell carcinoma by Pengzhou Kong, Pengzhou Kong, Pengzhou Kong, Ye Jiao, Ye Jiao, Meng Sun, Meng Sun, Zhinan Zhou, Zhinan Zhou, Yingying Zhang, Yingying Zhang, Xin Yang, Xin Yang, Jing Ren, Jing Ren, Mengyuan Yang, Mengyuan Yang, Yanyan Dong, Yanyan Dong, Yanyan Dong, Bin Song

“…Esophageal squamous cell carcinoma (ESCC) is the most prevalent primary malignant esophageal tumor in China and has a poor prognosis, but lacks effective diagnostic and prognostic biomarkers. Through single-sample gene set enrichment analysis (ssGSEA), we conducted immune genomic analysis based on 28 immune features using transcriptomic data from 155 ESCC cases. …”
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Multi-omics approaches for understanding gene-environment interactions in noncommunicable diseases: techniques, translation, and equity issues by Robel Alemu, Nigussie T. Sharew, Yodit Y. Arsano, Muktar Ahmed, Fasil Tekola-Ayele, Tesfaye B. Mersha, Azmeraw T. Amare

“…These diseases arise from the complex interactions between genetic, behavioral, and environmental factors, necessitating a thorough understanding of these dynamics to identify effective diagnostic strategies and interventions. Although recent advances in multi-omics technologies have greatly enhanced our ability to explore these interactions, several challenges remain. …”
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Beyond the Ear, the Hidden Threat of Paecilomyces Neuro-Otological Infection: A Case Report by Jing Hern Khoo, Izny Hafiz Zainon, Hafizah Husna Johari, Ida Sadja’ah Sachlin

“…Differentiating it from cholesteatoma also presents a diagnostic challenge clinically and radiologically. …”
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A Hybrid Efficient U-Net Framework for Detection of Anterior Belly of the Digastric Muscle on Ultrasonography by Sule Erdem, Suheda Erdem, Muammer Turkoglu, Abdulkadir Sengur, Nebras M. Sobahi

“…The model can contribute to clinical diagnostic processes with its ability to accurately detect small and large structures. …”
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Isolated IgA Anti-β2 Glycoprotein I Antibodies in Patients with Clinical Criteria for Antiphospholipid Syndrome by Raquel Ruiz-García, Manuel Serrano, José Ángel Martínez-Flores, Sergio Mora, Luis Morillas, María Ángeles Martín-Mola, José M. Morales, Estela Paz-Artal, Antonio Serrano

“…However, they are not currently considered to be laboratory criteria due to the heterogeneity of published works and the use of poor standardized diagnostic systems. We have aimed to assess aPL antibodies in a group of patients with clinical manifestations of APS (C-APS) to evaluate the importance of the presence of IgA aB2GPI antibodies in APS and its relation with other aPL antibodies. …”
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Role of Neuron-Specific Enolase in the Diagnosis and Disease Monitoring of Sarcoidosis by Noriaki Sunaga, Yasuhiko Koga, Yoshimasa Hachisu, Koichi Yamaguchi, Masaki Aikawa, Norimitsu Kasahara, Yosuke Miura, Hiroaki Tsurumaki, Masakiyo Yatomi, Reiko Sakurai, Toshitaka Maeno, Takeshi Hisada

“…Although angiotensin-converting enzyme (ACE) and soluble interleukin 2 receptor (sIL-2R) are traditionally used for the diagnosis of sarcoidosis, specific diagnostic markers remain to be determined. In the current study, we found that serum neuron-specific enolase (NSE) levels were elevated in patients with sarcoidosis. …”
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The Utility of Perirenal Fat in Determining the Risk of Onset and Progression of Diabetic Kidney Disease by Hongtu Hu, Wei Liang, Zongwei Zhang, Zikang Liu, Fan Chu, Yan Bao, Jialu Ran, Guohua Ding

“…Based on the cutoff value from the ROC diagnostic test in the cross-sectional study, patients were divided into two groups: higher PFT (H-PFT) and lower PFT (L-PFT). …”
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MECHANISMS AND CLINICAL PERSPECTIVES OF ALLERGEN-SPECIFIC IMMUNOTHERAPY by Leila Akhvlediani, Marina Izmailovich, Meruyert Gazaliyeva, Anna Skvortsova, Kanan Tanriverdiev

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Hyperuricemia prevalence and its risk factors in uremic patients undergoing maintenance hemodialysis by Meng Zhang, Gaoqiankun Huang, Xiaorong Bao, Qingmei Yang

“…Results The median SUA level of the enrolled patients was 458.50 (392.25, 510.75) μmol/L. 134 (66.34%) candidates met the diagnostic criteria of hyperuricemia. The median SUA level in HUA group was 491.00 (459.50, 543.50) μmol/L. …”
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Xanthogranulomatous Pyelonephritis with Incomplete Double Ureter by Yutaro Hayashi, Takashi Kawahara, Yusuke Hattori, Kota Shimokihara, Sohgo Tsutsumi, Daiji Takamoto, Taku Mochizuki, Jun-ichi Teranishi, Yasushi Yumura, Yasuhide Miyoshi, Masako Otani, Hiroji Uemura

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Pollen of <i>Pterocarya</i> (Juglandaceae) representatives from natural habitats and St. Petersburg environments by O. A. Gavrilova, G. A. Firsov, D. A. Gornov, A. N. Semenov, A. V. Volchanskaya

“…The palynonomophological description is diagnostic for the genus Pterocarya. The Pterocarya pollen is well distinguishable from other wind-pollinated taxa; however, species identification by pollen for spore-pollen analysis is not practicable. …”
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Focal Segmental Glomerulosclerosis Preceding Type 2 Papillary Renal Cell Carcinoma by Dominik Dabrowski, Ekin Ozluk, Silvia Barbeito, Eric X. Wei

“…Because FSGS only sparingly affects the kidney and is a common glomerulopathy in adults, it is reasonable to complete comprehensive diagnostic studies and commence medically necessary treatment, especially in the background of other renal comorbidities. …”
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Implementation outcomes of HIV self-testing in low- and middle- income countries: A scoping review. by Adovich S Rivera, Ralph Hernandez, Regiel Mag-Usara, Karen Nicole Sy, Allan R Ulitin, Linda C O'Dwyer, Megan C McHugh, Neil Jordan, Lisa R Hirschhorn

“…The high occurrence of user errors was a common feasibility issue reported by studies, although, diagnostic accuracy remained high. HIV-ST was associated with higher program costs but can still be cost-effective if kit prices remain low and HIV detection improves. …”
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Metagenomic next-generation sequencing for lung cancer low respiratory tract infections diagnosis and characterizing microbiome features by Yao Liu, Bohan Yang, Qi Qi, Shijie Liu, Yiheng Du, Linlin Ye, Qiong Zhou

“…BackgroundThe capability of mNGS in diagnosing suspected LRTIs and characterizing the respiratory microbiome in lung cancer patients requires further evaluation.MethodsThis study evaluated mNGS diagnostic performance and utilized background microbial sequences to characterize LRT microbiome in these patients. …”
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Association between clinical and sonographic patterns of major peripheral arterial occlusion among patients presenting with lower limb dry gangrene at a single center in Western Ug... by Alfred Omo, Emmanuel Barasa, Edson Tayebwa, Moses Acan, Emile Ndanga, Aturinde Mercy

“…It is among the leading indications for lower limb amputation; however, in situations where timely access of accurate diagnostic and revascularization services are limited, irrational amputations are performed based on mere physical assessment of a specific occluded major arterial segment, consequently preceded with gangrene recurrence on the same limb stump due to physical examination inaccuracies. …”
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Psychological Well-Being in Adolescents with Different Types of Socialization by Elena N. Volkova

“…The purpose of this article is to study the components of adolescents’ psychological well-being as related to different types of socialization. Methods. The diagnostic complex of the study included the 20-item version of the EPOCH questionnaire (Kern et al., 2016) and the prosocial behaviour scale from the Success and Difficulty Questionnaire for Children 11–17 years old (SDQ, Goodman et al., 2005), adapted for Russian-speaking sample. …”
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Quantitative evaluation of the wide-field fundus photographs in eyes with severe stage 3 and stage 4A retinopathy of prematurity by Sadik Etka Bayramoglu, Nihat Sayin, Gurkan Erdogan

“…The dragging of the posterior pole can be an important diagnostic indicator for the diagnosis of stage 4A. …”
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Enzyme-linked immunosorbent assay for post-slaughter diagnosis of bovine leukosis by A. R. Mustafayev, M. O. Baratov

“…Results of post-slaughter diagnostic tests for bovine leukosis with enzyme-linked immunosorbent assay are described in the paper. …”
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Serum Tumor Necrosis Factor-α and Interferon-γ Levels in Pediatric Mycoplasma pneumoniae Pneumonia: A Systematic Review and Meta-Analysis by Ying Wang, Yongsheng Zhang, Wenting Lu, Liying Wang

“…Because infection by different pathogens has variable effects on serum TNF-α and IFN-γ levels, the finding could be helpful in developing novel diagnostic methods.…”
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An Enhanced Approach Using AGS Network for Skin Cancer Classification by Hwanyoung Lee, Seeun Cho, Jiyoon Song, Hoyoung Kim, Youjin Shin

“…However, accurately diagnosing skin cancer remains challenging for dermatologists, as multiple types of skin cancer often appear visually similar. The diagnostic accuracy of dermatologists ranges between 62% and 80%. …”
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