White matter hyperintensities and cholinergic degeneration as Lewy body disease by Sungwoo Kang, Seun Jeon, Yeoju Kim, Su‐Hee Jeon, Minsun Choi, Young‐gun Lee, Mijin Yun, Byoung Seok Ye

“…Methods A total of 407 patients with cognitive impairment meeting the diagnostic criteria for AD, DLB, or both (AD+DLB) were assessed. …”
Get full text

Noninvasive diagnosis model for predicting significant liver inflammation in patients with chronic hepatitis B in the immune-tolerant phase by Shanshan Chen, Lu Huang, Yili Chu, Jiangshan Lian, Hui Shao, Tingting Wang, Xuehan Zou, Haijun Huang

“…Then the least absolute shrinkage and selection operator and multivariable logistic regression were used to identify the significant independent risk factors and establish a predictive model. A diagnostic nomogram was constructed. Calibration curves, decision curve analysis, and receiver operating characteristic curves were utilized to evaluate the performance of the nomogram. …”
Get full text

Development and Validation of LAMP Assays for Distinguishing MPXV Clades with Fluorescent and Colorimetric Readouts by Nazente Atceken, Sara Asghari Dilmani, Ahmed Choukri Abdullah, Mutlu Sarıkaya, Defne Yigci, Gozde Korkmaz, Savas Tasoglu

“…As a result, we successfully developed three highly specific molecular diagnostic tests that distinctly differentiate between MPXV clades, delivering essential tools for the precise diagnosis and effective control of Mpox.…”
Get full text

A comprehensive analysis of the uterine microbiome in endometrial cancer patients - identification of Anaerococcus as a potential biomarker and carcinogenic cofactor by Olga Kuźmycz, Aleksandra Kowalczyk, Aleksandra Bolanowska, Anna Drozdzowska, Jakub Lach, Jakub Lach, Wiktoria Wierzbińska, Wiktoria Wierzbińska, Tomasz Kluz, Tomasz Kluz, Paweł Stączek

“…The in vitro findings suggest its role in endometrial carcinogenesis, underscoring its potential as a target for future diagnostic and therapeutic applications.…”
Get full text

Peak Occurrence of Retinal Detachment following Cataract Surgery: A Systematic Review and Pooled Analysis with Internal Validation by Rabea Kassem, Yoel Greenwald, Asaf Achiron, Idan Hecht, Vitaly Man, Liron Ben haim, Amir Bukelman

“…Timing of retinal detachment (RD) following cataract surgery is of importance for both diagnostic and prognostic factors. However, results on RD onset-time following cataract surgery have been conflicting. …”
Get full text

Functional Disorders of the Biliary Tract and Cholelithiasis: Analysis of a Possible Relationship by Yu. O. Shulpekova, I. R. Popova, V. M. Nechaev

“…Aim: Diagnostic criteria for functional disorders of the biliary tract are presented in the materials of the Rome IV consensus, as well as expert councils of Russian and foreign specialists. …”
Get full text

Predicting Individual Systems Thinking Skills Using Bayesian Network Approach by Niamat Ullah Ibne Hossain, Raed Jaradat, Morteza Nagahi, Alex Gorod

“…Although several methods exist in the extant literature to appraise the ST skills of practitioners, none has been recommended for prediction and diagnostic purposes. To fill this void, this research study aims to develop and validate a Bayesian network tool that incorporates seven main factors and the corresponding underpinning sub-factors that influence individual ST skills, as identified by Jaradat and Keating. …”
Get full text

Transcriptomic and proteomic profiling identifies feline fibrosarcoma as clinically amenable model for aggressive sarcoma subtypes by Mikiyo Weber, Daniel Fuchs, Amiskwia Pöschel, Erin Beebe, Zuzana Garajova, Armin Jarosch, Laura Kunz, Witold Wolski, Lennart Opitz, Franco Guscetti, Mirja C. Nolff, Enni Markkanen

“…Clear inter-tissue differences allow identification of significantly upregulated and tumor-exclusive features that represent potential targets for diagnostic and therapeutic approaches. While feline FSA are characterized by hyperactive EIF2, TP53 and MYC signaling, immune-related and neuronal pathways emerge as modulators of tumor aggressiveness and immunosuppression. …”
Get full text

Interprofessional teaching rounds in medical education: improving clinical problem-solving ability and interprofessional collaboration skills by Peiwen Yang, Ting Xiong, Xiyuan Dong, Shulin Yang, Jing Yue

“…A quiz including medical knowledge of gynecological and obstetric diseases was used to assess the students’ diagnostic and treatment abilities after teaching rounds. …”
Get full text

Clonal hematopoiesis in patients with autoimmune thrombocytopenia: an international multicenter study by Bruno Fattizzo, Alfredo Marchetti, Alessandro Bosi, Carmelo Gurnari, Juri Alessandro Giannotta, Giacinto Luca Pedone, Elena Rossi, Valentina Carrai, Andrea Guido, Filippo Brioschi, Monica Carpenedo, Monica Crugnola, Domenica Caramazza, Livia Leuzzi, Monia Marchetti, Gabriele Merati, Simona Malato, Fabrizio Vianello, Andrea Patriarca, Hussein Awada, Marta Bortolotti, Marta Canzi, Niccolò Bolli, Marco Capecchi, Frederick Chen, Andrea Artoni, Jaroslaw P. Maciejewski, Wilma Barcellini

“…Abstract: Diagnostic boundaries between immune thrombocytopenia (ITP) and other thrombocytopenic states, such as thrombocytopenic myelodysplastic syndromes, may be difficult to establish, and the detection of somatic mutations by next-generation sequencing (NGS) may be of aid. …”
Get full text

Identification of Plasma Proteins Associated with Alzheimer's Disease Using Feature Selection Techniques and Machine Learning Algorithms by Zakaria Mokadem, Mohamed Djerioui, Bilal Attallah, Youcef Brik

“…This non-invasive and affordable diagnostic method has the potential to make Alzheimer’s screening accessible to a broader population. …”
Get full text

Evaluation of veterinary laboratory proficiency based on results of interlaboratory comparisons organized by FGBI “ARRIAH” in 2018–2019 by A. Yu. Sukharkov, Z. B. Nikonova, O. P. Byadovskaya, A. S. Pershin, M. I. Shulpin, I. A. Chvala

“…The need for unswerving trust in the quality of laboratory performance is a matter of importance not only for service providers and customers, but also for inspecting organiza­tions, accreditation bodies, etc. that establish performance requirements for diagnostic laboratories. Incorrect laboratory test results can lead to a misdiagnosis and, therefore, to grave consequences. …”
Get full text

Visual-Evoked-Response-Supported Outcome of Intravitreal Erythropoietin in Management of Indirect Traumatic Optic Neuropathy by Mohammad Ahmad Rashad, Ahmed Abdel Meguid Abdel Latif, Hazem A. Mostafa, Samah Mahmoud Fawzy, Mahmoud Abdel Meguid Abdel Latif

“…A case series that included two groups of ITON patients: recent ITON group (<3 months trauma duration; 7 eyes) and old duration ITON group (3–36 months; 7 eyes). Diagnostic computerized tomography (CT) and baseline flash visual evoked response (VER) were performed at the presentation time. …”
Get full text

Partial unilateral ovarian torsion in a red-eared slider turtle (Trachemys scripta elegans) by Alessandro Vetere, Martina Gavezzoli, Lucia Victoria Bel, Rosanna Di Lecce, Martina Fumeo, Mattia Bonazzi, Francesco Di Ianni

“…A 14-year-old female Trachemys scripta was presented with inappetence and lethargy for approximately 2 weeks. Diagnostic tests, including complete blood work, radiography, and ultrasound, were performed. …”
Get full text

Advancing the understanding of Naegleria fowleri: Global epidemiology, phylogenetic analysis, and strategies to combat a deadly pathogen by Awadh Alanazi, Sonia Younas, Hasan Ejaz, Muharib Alruwaili, Yasir Alruwaili, Bi Bi Zainab Mazhari, Muhammad Atif, Kashaf Junaid

“…This review provides a detailed overview of N. fowleri epidemiology, transmission dynamics, phylogenetic diversity, state-of-the-art diagnostic techniques, therapeutic approaches, and preventive measures. …”
Get full text

Knockdown of hexokinase 2 results in a decreased expression level of the glycolytic enzymes PFKP, BPGM, and GPI in RKO cell line by M. S. Fedorova, I. Y. Karpova, A. V. Lipatova, E. A. Pudova, Z. G. Guvatova, D. V. Kochetkov, A. V. Chaika, B. Y. Alekseev, M. V. Kiseleva, A. D. Kaprin, A. V. Kudryavtseva, A. V.  Snezhkina

“…The study of the key aspects of colorectal cancer formation and progression is necessary to develop new approaches to its therapy, as well as to search for new diagnostic, prognostic and predictive biomarkers of CRC. …”
Get full text

Evaluation of NxTAG Respiratory Pathogen Panel and Comparison with xTAG Respiratory Viral Panel Fast v2 and Film Array Respiratory Panel for Detecting Respiratory Pathogens in Naso... by K. H. Chan, K. K. W. To, P. T. W. Li, T. L. Wong, R. Zhang, K. K. H. Chik, G. Chan, C. C. Y. Yip, H. L. Chen, I. F. N. Hung, J. F. W. Chan, K. Y. Yuen

“…The results of this study should help clinical laboratory professionals to be aware of the different performances of commercially available molecular multiplex RT-PCR assays that are commonly adopted in many clinical diagnostic laboratories.…”
Get full text

Head and Neck Paragangliomas: 16-year Single-center Experience and Mini Review on Diagnosis, Treatment, and Follow-up by Gokce AYDEMIR, Fazil Necdet ARDIC, Cuneyt Orhan KARA, Ferda BIR

“…The additional goal is to contribute to the existing knowledge on head and neck paraganglioma, with a particular emphasis on refining diagnostic algorithms, treatment selection, and follow-up procedures. …”
Get full text

The Effectiveness of Dipstick for the Detection of Urinary Tract Infection by Isaac Dadzie, Elvis Quansah, Mavis Puopelle Dakorah, Victoria Abiade, Ebenezer Takyi-Amuah, Richmond Adusei

“…The balance between the choices of UTI diagnostic tools in most primary care settings has been settled for by the more rapid, less labour-intensive dipstick. …”
Get full text

Resnet-1DCNN-REA bearing fault diagnosis method based on multi-source and multi-modal information fusion by Xu Chen, Wenbing Chang, Yongxiang Li, Zhao He, Xiang Ma, Shenghan Zhou

“…Finally, the tree-structured parzen estimator (TPE) algorithm was utilized to realize the integration of two models in order to improve the diagnostic effect of a single model and obtain the final bearing fault diagnosis results. …”
Get full text