The Potential of Antibodies Against the Phosphatidylserine / Prothrombin Complex as a Biomarker in Antiphospholipid Syndrome by Piotr Pasek, Witold Czyż, Julia Kulbacka, Julia Kacperczyk, Marta Chuncia-Ileczko, Michalina Wójcikiewicz, Filip Arczewski, Karol Dziedzic, Maciej Wojszczyk, Damian Zys, Julia Ryniecka

“…Purpose The object of this review is to assess whether aPS/PT complex serves as an effective diagnostic marker in the pathogenesis of complications associated with APS and other connective tissue disorders. …”
Get full text

Optical Coherence Tomography Angiography of Purtscher Retinopathy after Severe Traffic Accident in 16-Year-Old Boy by Hassan Hamoudi, Marie Krogh Nielsen, Torben Lykke Sørensen

“…OCTA is a valuable noninvasive diagnostic examination in Purtscher retinopathy, and fluorescein angiography became redundant in this case.…”
Get full text

A Target Domain-Specific Classifier Weight Partial Transfer Adversarial Network for Bearing Fault Diagnosis by Yin Bai, Xiangdong Hu, Kai Zheng, Yunnong Chen, Yi Tang

“…Due to the strict constraints, partial transfer learning can address a more practical diagnostic scenario. In view of this, this paper proposes a target domain-specific classifier weight partial transfer adversarial network. …”
Get full text

Deep Learning Architecture to Infer Kennedy Classification of Partially Edentulous Arches Using Object Detection Techniques and Piecewise Annotations by Zohaib Khurshid, MRes, FDTFEd, FHEA, Maria Waqas, PhD, Shehzad Hasan, PhD, Shakeel Kazmi, PhD, Muhammad Faheemuddin, FCPS

“…It can diagnose multiple dental issues simultaneously within an image, enhancing diagnostic capabilities for dental practitioners. Conclusions: Despite a small dataset, satisfactory results were achieved through tailored hyperparameters and a piecewise annotation scheme.…”
Get full text

A multifunctional mesoporous silica drug delivery nanosystem that ameliorates tumor hypoxia and increases radiotherapy efficacy by Yanhong Chu, LiFeng Wang, Yaohua Ke, Xiaoyu Feng, Wenmei Rao, Wei Ren, Kai Xin, Yan Wang, Lixia Yu, Baorui Liu, Qin Liu

“…Safety assessments confirmed the absence of MSN@R837-Mn/ZnO2 toxicity, highlighting its potential as a promising approach with dual functionality for the diagnostic imaging and treatment of cancer.…”
Get full text

Management of the Acute Scrotum in a District General Hospital: 10-Year Experience by Lukas Tajchner, John O. Larkin, Michael G. Bourke, Ronan Waldron, Kevin Barry, Paul W. Eustace

“…Testicular salvage depends critically on early surgical intervention, so the delay incurred in diagnostic imaging may extend the period of ischaemia. …”
Get full text

Wood's lamp for early detection of Microsporum Canis tinea capitis in children by Dexiang Sun, Jinming Lu, Tao Liu, Jun Wang

“…Conclusions: Wood's lamp is a valuable, cost-effective diagnostic tool for tinea capitis, especially when combined with animal contact history, supporting its use in primary healthcare.…”
Get full text

Application Strategies of Super-Enhancer RNA in Cardiovascular Diseases by Yi He, Yuwei Cai, Yanyan Cao, Yan Wang, Jing Wang, Hu Ding

“…We also explore their role in the occurrence and development of CVDs, as well as their potential as diagnostic biomarkers and therapeutic targets. Currently, therapies targeting seRNAs are a research hotspot. …”
Get full text

An Unusual Presentation of COVID-19 Associated Multisystem Inflammatory Syndrome in Adults (MIS-A) in a Pregnant Woman by Mohamed Rishard, Suren Perera, Kushan Jayasinghe, Amila Rubasinghe, Sanjaya Athapaththu, Malindu Edirisinghe, Prabhodana Ranaweera, Tushani Ranawaka, Athula Kaluarachchi, Priyankara Jayawardana, Zacky Haniffa

“…However, MIS-A in pregnancy is an extremely rare presentation that can cause a huge diagnostic dilemma to caregivers. We describe the successful management of a pregnant woman with MIS-A following SARS-CoV-2 infection.…”
Get full text

Metabolomic Evaluation of Chronic Periodontal Disease in Older Adults by Wellington F. Rodrigues, Camila B. Miguel, Ferdinando Agostinho, Gabriela V. da Silva, Javier E. Lazo-Chica, Sandra M. Naressi Scapin, Marcelo H. Napimoga, Carlos A. Trindade-da-Silva, José E. Krieger, Alexandre da Costa Pereira, Carlo J. Freire Oliveira, Siomar de Castro Soares, Carlos Ueira-Vieira

“…Further analysis showed that among the 15 metabolites, two (5-aminovaleric acid and serine, 3TMS derivative) were found at higher concentrations in the crevicular fluid, indicating their potential diagnostic power for periodontal disease in older adults. …”
Get full text

Credit Card Fraud Detection through Parenclitic Network Analysis by Massimiliano Zanin, Miguel Romance, Santiago Moral, Regino Criado

“…While this has hitherto been tackled through data analysis techniques, the resemblances between this and other problems, like the design of recommendation systems and of diagnostic/prognostic medical tools, suggest that a complex network approach may yield important benefits. …”
Get full text

Diffuse Arterial Thrombosis as a First Manifestation of Occult Malignancy by Marija Vavlukis, Irina Kotlar, Emilija Chaparoska, Emilija Antova, Sasko Kedev

“…Further investigation of this young patient with no risk factors for hypercoagulable state and no other comorbidities led to complete work-up including diagnostic evaluation for malignancy. The suspicion was confirmed after performing upper endoscopy with biopsy, which revealed malignant neoplasm of the stomach. …”
Get full text

Evaluation of a Deep Learning Model for Automatic Detection of Schizophrenia Using EEG Signals by Swetha Padmavathi Polisetty, Radhamani Ellapparaj, Karthikeyan M P

“…This robust end-to-end system is expected to be useful as a diagnostic tool for clinicians and provide valuable support in the assessment of schizophrenia due to its automated nature for EEG processing.…”
Get full text

Case Report: Pediatric pontine abscess and ecthyma gangrenosum due to Pseudomonas aeruginosa septicemia by Jonathan Theros, Madison Wolfe, Larry Kociolek, Larry Kociolek, Irini N. Kolaitis, Irini N. Kolaitis

“…Prompt action through interdisciplinary care meetings and avoidance of early diagnostic closure resulted in an excellent neurological outcome for this patient with this rare case of a P. aeruginosa brainstem abscess.…”
Get full text

Diagnosis of depression based on facial multimodal data by Nani Jin, Renjia Ye, Peng Li

“…Traditional scale-based depression diagnosis methods often have problems of strong subjectivity and high misdiagnosis rate, so it is particularly important to develop automatic diagnostic tools based on objective indicators.MethodsThis study proposes a deep learning method that fuses multimodal data to automatically diagnose depression using facial video and audio data. …”
Get full text

Relationship between neutropenia caused by nanoliposomal irinotecan/fluorouracil/leucovorin and treatment outcomes in the NAPOLEON-2 study (NN-2301) by Tomonori Araki, Yuki Sonoda, Mototsugu Shimokawa, Taiga Otsuka, Kohei Hayashi, Takuya Honda, Kazuhiko Nakao, Taro Shibuki, Junichi Nakazawa, Shiho Arima, Keisuke Miwa, Yoshinobu Okabe, Futa Koga, Yujiro Ueda, Yoshihito Kubotsu, Hozumi Shimokawa, Shigeyuki Takeshita, Azusa Komori, Kazuo Nishikawa, Satoshi Otsu, Ayumu Hosokawa, Hisanobu Oda, Tatsunori Sakai, Shuji Arita, Machiko Kawahira, Hiroki Taguchi, Kengo Tsuneyoshi, Yasunori Kawaguchi, Toshihiro Fujita, Takahiro Sakae, Tsuyoshi Shirakawa, Toshihiko Mizuta, Kenji Mitsugi

Get full text

Preparation of future teachers for innovative activities in pedagogical and technological educational environment by N. I. Naumkin, N. N. Shekshaeva, V. F. Kupryashkin, E. V. Zabrodina

“…The environment includes conceptually-targeted, infrastructural, content-based, psychological-didactic, methodological-technological and relaxation-diagnostic components, its features are the following: 1) focus on innovative training of technology teachers as directly related to the material objects of the innovative economy of the country; 2) universality in the form of the possibility of using it to solve other educational tasks; 3) graphical visualisation of the environment model with an indication of the hierarchy and interrelation of components, its scale, combinatoricity and functional sufficiency; 4) compliance of the environment with all the requirements of regulatory documents on educational activities at the university; 5) possibility of full-scale implementation of modern approaches to learning (innovative, personalised, environmental, project, etc.); 6) possibility of constant monitoring and control of the implementation of the environment within its relaxation and diagnostic component; 7) use of modern educational technologies, including digital; 8) possibility of obtaining specialised knowledge and studying other disciplines within the framework of using network learning; 9) innovativeness of the environment, determined by the novelty of the approach to teaching the teachers innovation technology and its effectiveness.To teach innovation activity in this environment, a model of a methodological system for the formation of competence in innovation activity among future technology teachers has been created, combining conceptually-targeted, meaningful, instrumental-activity and reflexive-evaluative components. …”
Get full text

Study of senile astheny markers against the background of acute inflammatory process in elderly and senile patients in emergency abdominal surgery by M. B. Danyliuk, S. M. Zavhorodnii, Ye. R. Fedotov, Ye. K. Mykhalchenko, I. V. Dobrodub

“…The aim of our work was to determine the influence of the acute inflammatory process on the diagnostic value of markers of senile asthenia in emergency abdominal surgery. …”
Get full text

AI-Driven Innovations for Early Sepsis Detection by Combining Predictive Accuracy With Blood Count Analysis in an Emergency Setting: Retrospective Study by Tai-Han Lin, Hsing-Yi Chung, Ming-Jr Jian, Chih-Kai Chang, Hung-Hsin Lin, Chiung-Tzu Yen, Sheng-Hui Tang, Pin-Ching Pan, Cherng-Lih Perng, Feng-Yee Chang, Chien-Wen Chen, Hung-Sheng Shang

“…Although the Sequential Organ Failure Assessment (SOFA) score standardizes the diagnosis of organ dysfunction, early sepsis detection remains challenging due to its insidious symptoms. Current diagnostic methods, including clinical assessments and laboratory tests, frequently lack the speed and specificity needed for timely intervention, particularly in vulnerable populations such as older adults, intensive care unit (ICU) patients, and those with compromised immune systems. …”
Get full text

Infectivity in full-term placenta of Zika viruses with different lipid profiles by Eva Mazzetto, Alessio Bortolami, Davide Bovo, Matteo Stocchero, Elisa Mazzacan, Alessandra Napolitan, Valentina Panzarin, Maria Rosa Tran, Gianpiero Zamperin, Adelaide Milani, Andrea Fortin, Michela Bigolaro, Paola Pirillo, Matteo Pagliari, Claudia Zanardello, Giuseppe Giordano, Maria Teresa Gervasi, Eugenio Baraldi, Calogero Terregino, Carlo Giaquinto, Francesco Bonfante

Get full text