Two Cases of γ-Heavy Chain Disease and a Review of the Literature by I. Ramasamy, Z. Rudzki

“…We describe newer biochemical diagnostic tools (HevyLite measurement, capillary electrophoresis, and immunotyping) that can aid in the characterisation of γ-HCD. …”
Get full text

Perspectives in HPV Secondary Screening and Personalized Therapy Basing on Our Understanding of HPV-Related Carcinogenesis Pathways by Aleksander Celewicz, Marta Celewicz, Michał Michalczyk, Rafał Rzepka

“…It is imperative to find new diagnostic methods for accurately pointing out patients at high risk of developing malignant disease and developing personalized treatment. …”
Get full text

Dandy-Walker Syndrome. Case Report and Literature Review by William Ernesto González Águila, Osiris Intento García, Nilda Beatriz Cortizo Martínez

“…The diagnosis can be carried out during the prenatal or postnatal stage, clinically and diagnostic imaging studies. We present the case of a newborn who was admitted to the Neonatal Intensive Care Unit due to hypotonic, tongue protrusion with sucking disorders. …”
Get full text

Clinical case – medulloblastoma by A. Kablytė, R. Gleiznienė

“…Although tumor biopsy remains the gold standard for the diagnosis of medulloblastoma, diagnostic imaging methods such as computed tomography (CT) and magnetic resonance imaging (MRI) are very important as well. …”
Get full text

Mitochondrial Neurogastrointestinal Encephalomyopathy: Novel Pathogenic Mutation in Thymidine Phosphorylase Gene in a Patient from Cape Verde Islands by Catarina Falcão de Campos, Miguel Oliveira Santos, Rafael Roque, Isabel Conceição, Mamede de Carvalho

“…A 19-year-old Cape Verdean patient with a history since childhood of recurrent episodes of nausea, vomiting, diarrhoea and painful abdominal distension associated with progressive motor disability with difficulty in climbing stairs and running and clumsiness with her hands. The diagnostic workup was suggestive of MNGIE. Genetic screening of the TYMP gene identified a novel mutation (c. 1283 G>A). …”
Get full text

Spatial and Temporal Variability of Polycyclic Aromatic Hydrocarbons in Sediments from Yellow River-Dominated Margin by Su Ding, Yunping Xu, Yinghui Wang, Xinyu Zhang, Liang Zhao, Jiaping Ruan, Weichao Wu

“…The applications of molecular diagnostic ratios and principal component analysis suggest that PAHs are predominantly produced by the coal and biomass combustion, whereas the contribution of petroleum combustions slightly increased after the 1970s, synchronous with an increasing usage of oil and gas in China.…”
Get full text

FundusNet: A Deep-Learning Approach for Fast Diagnosis of Neurodegenerative and Eye Diseases Using Fundus Images by Wenxing Hu, Kejie Li, Jake Gagnon, Ye Wang, Talia Raney, Jeron Chen, Yirui Chen, Yoko Okunuki, Will Chen, Baohong Zhang

“…Early-stage detection of neurodegenerative diseases is crucial for effective clinical treatment. However, current diagnostic methods are expensive and time-consuming. …”
Get full text

Multiple Myeloma with Foamy Mott Cells by Karen Nalbandyan, Daniel Benharroch, Benzion Samueli, Michael Kafka, Anna Gourevitch

“…When abundant, they impart a foamy appearance to the tumor cells, which is a potential source for diagnostic pitfalls. Herein, we report the case of a patient who presented with skeletal pain and CT confirmed lytic lesions. …”
Get full text

An Unusual Extremely Distant Noncommunicating Uterine Horn with Myoma and Adenomyosis Treated with Laparoscopic Hemihysterectomy by Michele Morelli, Roberta Venturella, Rita Mocciaro, Daniela Lico, Fulvio Zullo

“…After ultrasound examination, the patient underwent diagnostic hysteroscopy and operative laparoscopy which confirmed the clinic suspect of an unicornuate uterus. …”
Get full text

Long non-coding RNA involved in the carcinogenesis of human female cancer - a comprehensive review by Nazia Afroze, Madhumitha K. Sundaram, Shafiul Haque, Arif Hussain

“…The review curates a list of the key players and their effect on cellular processes. lncRNA molecules show immense potential to be used as diagnostic and prognostic indicators and in therapeutic strategies. …”
Get full text

Application of immunohistochemical markers in mycosis fungoides by SHAO Kaixin, LIU Xiangjun, TANG Zhenzhen

“…Immunohistochemical (IHC) staining is a commonly used diagnostic method in clinical practice. Common markers such as CD4, CD8, CD20, and CD30 have different expression patterns in mycosis fungoides. …”
Get full text

Value of Magnetic Resonance Imaging for Diagnosis of Dentigerous Cyst by Antonione Santos Bezerra Pinto, André Luiz Ferreira Costa, Neiandro dos Santos Galvão, Thásia Luiz Dias Ferreira, Sérgio Lúcio Pereira de Castro Lopes

“…Odontogenic cysts have a high prevalence in the dental clinic population, with dentigerous cyst being one of the most frequent ones and whose aetiology involves accumulation of fluid between the reduced enamel epithelium and the crown of an unerupted tooth. In the diagnostic process of these lesions, one should consider complementary imaging exams such as conventional radiography and computed tomography, which are commonly used for providing anatomical information on the tissues compromised by the lesion, but not on the nature of it. …”
Get full text

Epithelioid Hemangioma of the Carpus Presenting as Aneurysmal Bone Cyst by Juston Fan, DO, William H. Fang, DO, MS, Evelyn Thomas, DO, Ali Nael, MD, Mark N. Halikis, MD, Amirhossein Misaghi, MD

“…Its varied presentation poses diagnostic challenges because of its ability to mimic other tumors. …”
Get full text

Enteric Fever as an Antecedent to Development of Miller-Fisher Syndrome and Possible Role of COVID-19 Vaccination by Tayyaba Binte Saleem, Muhammad Ibrahim, Faizan Fazal, Mohammad Ebad Ur Rehman, Ali Ahmad Ijaz, Humera Nasim

“…We conclude that Miller-Fisher syndrome should be considered in the diagnostic workup of patients presenting with new sensorimotor deficits following diarrheal illnesses and/or COVID-19 mRNA vaccination. …”
Get full text

Intervention Methodology for the Rehabilitation of Damaged Reinforced Concrete Structures by Moulaï Abdellah Bouabdallah

“…It is therefore important to establish a diagnostic methodology in order to properly specify the origin of the damage. …”
Get full text

Application, Challenges, and Prospects of Large Language Model in the Field of Traditional Chinese Medicine by CHEN Zijia, PENG Wenxi, ZHANG Dezheng, LIU Xin, WANG Zhifei

“…LLM has unique advantages in the field of traditional Chinese medicine (TCM), such as high consistency with the "Four Diagnostic Methods", perfect combination of natural language and self-supervised learning in TCM, the ability to adapt to the characteristics TCM formulas, and the assistance in TCM diagnosis and treatment. …”
Get full text

Macro-Aspartate Aminotransferase and Its Laboratory Detection: A Case Report by Goda Aleknavičiūtė-Valienė, Linas Černiauskas, Mantas Riauka, Dalius Vitkus

“…In the case of an isolated elevation of AST activity with no clinical indications of liver disease, diagnostic work-up for macro-AST should always be considered by physicians. …”
Get full text

Hemophagocytic Lymphohistiocytosis in Association with Primary Cutaneous Anaplastic Large Cell Lymphoma by Aneesh Basheer, Somanath Padhi, Ramesh Nagarajan, Vinoth Boopathy, Sudhagar Mookkappan, Nayyar Iqbal

“…We do suggest that HLH may pose diagnostic challenges in the evaluation of an underlying lymphoma and hence warrants proper evaluation for the underlying etiologies and/or triggering factors.…”
Get full text

Unique Cytokine Signature in the Plasma of Patients with Fibromyalgia by Jamie Sturgill, Elizabeth McGee, Victoria Menzies

“…The finding of this pattern of altered cytokine milieu not only supports the role of inflammation in FMS but also may lead to more definitive diagnostic tools for clinicians treating FMS. The TH2 suppression provides strong evidence of immune dysregulation in patients with FMS.…”
Get full text

Celiac Disease and Dermatologic Manifestations: Many Skin Clue to Unfold Gluten-Sensitive Enteropathy by Marzia Caproni, Veronica Bonciolini, Antonietta D'Errico, Emiliano Antiga, Paolo Fabbri

“…The knowledge about pathogenic, epidemiological, clinical, and diagnostic aspects of CD is increasing in recent years as well as those about DH, but some aspects still remain to be defined, in particular the possible pathogenetic mechanisms involved in the association between both CD and DH and CD and other immunological skin diseases. …”
Get full text