Frontotemporal Dementia as a Possible Manifestation of Primary Lateral Sclerosis: A Case Report and Literature Review by Kevin Qosja, Nicole M. Absar, Allen T. Yu

“…Primary lateral sclerosis (PLS) is currently defined as a restricted phenotype of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease with upper motor neuron (UMN) symptoms that causes slowly progressive spasticity. The diagnostic criteria of this disorder currently do not include any effects on frontal executive or other cortical functioning. …”
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Neonatal Cholestasis: A Red Alert for the Jaundiced Newborn by Dinesh Pashankar, Richard A Schreiber

“…Unravelling the etiopathogenesis of these neonatal cholestatic disorders will allow the development of novel diagnostic and therapeutic interventions that ultimately will effectuate the prognosis for these young patients.…”
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Summary of Canadian Guidelines for the Initial Management of Community-Acquired Pneumonia: An Evidence-Based Update by the Canadian Infectious Disease Society and the Canadian Thor... by Lionel A Mandell, Thomas J Marrie, Ronald F Grossman, Anthony W Chow, Robert H Hyland, Canadian CAP Working Group

“…The current guidelines represent a joint effort by the Canadian Infectious Diseases Society and the Canadian Thoracic Society, and they address the etiology, diagnosis and initial management of CAP. The diagnostic section is based on the site of care, and the treatment section is organized according to whether one is dealing with outpatients, inpatients or nursing home patients.…”
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An Unusual Case of Fulminant Type 1 Diabetes during the Second Trimester of Pregnancy by Tomohiro Okuda, Sadao Yamashita, Yoshio Ogino, Hisashi Kataoka, Jo Kitawaki

“…The condition met all the diagnostic criteria for fulminant type 1 diabetes, and was diagnosed as such. …”
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The Management of Iron Chelation Therapy: Preliminary Data from a National Registry of Thalassaemic Patients by Adriana Ceci, Laura Mangiarini, Mariagrazia Felisi, Franco Bartoloni, Angela Ciancio, Marcello Capra, Domenico D'Ascola, Paolo Cianciulli, Aldo Filosa

“…A new initiative was promoted by the Italian Ministry of Health, establishing a Registry for thalassaemic patients to serve as a tool for the development of cost-effective diagnostic and therapeutic approaches and for the definition of guidelines supporting the most appropriate management of the iron-chelating therapy and a correct use of the available iron-chelating agents. …”
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Multidisciplinary management of a patient with acute oesophageal necrosis and severe neurological symptoms with full recovery by Katrīna Terehova, Poļina Zaļizko, Krista Lazdovska, Raimonds Skumbiņš, Aldis Puķītis

“…It poses significant diagnostic and therapeutic challenges as it often presents with multiple comorbidities and a poor prognosis. …”
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Devotion to Clinical Psychology. To the anniversary of Irina Fedorovna Roshchina by N.V. Zvereva

“…The article highlights the main milestones in her biography and identifies her main areas of scientific interest, including: the study of normal and pathological aging, the methodology and diagnostic tools of clinical psychology, the theoretical and methodological issues of medical (clinical) psychology, as well as issues related to the training and education of young professionals and the preservation of the traditions of the Moscow School of Clinical Psychology. …”
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Streptococcus pneumoniae Coinfection in COVID-19 in the Intensive Care Unit: A Series of Four Cases by Shrey Shah, Chaitanya Karlapalem, Pratik Patel, Nikhil Madan

“…Current literature shows that diagnostic testing and antibiotic therapy for bacterial infections are not necessary upon admission in majority of patients with SARS-CoV-2 patients. …”
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Advances in micro-/nanorobots for cancer diagnosis and treatment: propulsion mechanisms, early detection, and cancer therapy by Baiyang Fu, Dan Luo, Chao Li, Yiwen Feng, Wenlong Liang

“…This review examines the current state of MNR applications and outlines future directions for their development, with the aim of enhancing their diagnostic and therapeutic efficacy and facilitating their integration into clinical practice.…”
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Congenital Lumbar Hernia with Lumbocostovertebral Syndrome: A Case Report and Review of the Literature by Ketan Vagholkar, Khojasteh Dastoor

“…A case of congenital lumbar hernia associated with lumbocostovertebral syndrome is presented in view of its rarity and diagnostic and therapeutic challenges. Discussion. Anatomical background of congenital lumbar hernia associated with various other anomalies especially of the musculoskeletal structures is discussed. …”
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Oxidative stress: an overview of past research and future insights by Aaser M. Abdelazim, Mosleh M. Abomughaid

“…Likewise, more work is needed on the utility of reactive oxygen species markers as a diagnostic tool.…”
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The Dynamic Modeling of Multiple Pairs of Spur Gears in Mesh, Including Friction and Geometrical Errors by Shengxiang Jia, Ian Howard, Jiande Wang

“…The effects of pitch and profile errors on the resultant input pinion angular velocity coherent-signal of the input pinion's average are discussed by investigating some of the common diagnostic functions and changes to the frequency spectra results.…”
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Sinonasal small-cell carcinoma combined concurrently with small-cell lung carcinoma: case report and literature review by Rencui Quan, Rencui Quan, Ling Han, Shihai Wu, Xianming Li

“…This case highlights the need for accurate diagnostic characterization of primary lesions and the need to formalize treatment paradigms using chemotherapy, radiation therapy, immunotherapy with immune checkpoint inhibitors, and targeted prophylactic cranial irradiation.…”
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New Concepts in the Diagnosis and Pathogenesis of Trichomonas vaginalis by Renuka Bhatt, Mary Abraham, Dino Petrin, Gary E Garber

“…There is a need for more accurate and rapid laboratory diagnostic methods, leading to better control and treatment strategies. …”
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Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis by Ivan Keogh, Rohana O’Connell, Sean Hynes, John Lang

“…Incidental subglottic mass was found at time of diagnostic microlaryngoscopy and biopsy confirmed subglottic EAF. …”
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DEVELOPMENT AND BASIC FEATURES OF INDIRECT ENZYME-LINKED IMMUNOSORBENT ASSAY FOR DETECTION OF ANTIBODIES AGAINST PORCINE EPIDEMIC DIARRHEA by A. V. Kanshina, A. S. Yakovleva, Ye. S. Orlova, A. V. Scherbakov

“…The test precision was above 90% pursuant to its repeatability and reproducibility, diagnostic specificity of the test amounted to 99.47%, and its sensitivity as compared to commercial ID Screen PEDV Indirect (IDvet, France) was 92% with very good compatibility of the two tests (k-criterion – 0.88) – 92%. …”
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Challenges Associated with Negative Pressure Pulmonary Oedema: A Case Report and Review by Wing Hoh Loo, Kay Mint Goh

“…It often presents a diagnostic dilemma, thus posing significant management challenges. …”
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Multilayer Mie Scattering Model for Investigation of Intracellular Structural Changes in the Nucleolus and Cytoplasm by S. Saltsberger, I. Steinberg, I. Gannot

“…Light scattering from biological cells has been used for many years as a diagnostic tool. Several simulation methods of the scattering process were developed in the last decades in order to understand and predict the scattering patterns. …”
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Gut dysbiosis in primary sarcopenia: potential mechanisms and implications for novel microbiome-based therapeutic strategies by Wei Yang, Si-Cong Si, Wei-Hua Wang, Jing Li, Yi-Xin Ma, Huan Zhao, Jia Liu

“…The mechanistic insights encompass a causal role of gut dysbiosis in primary sarcopenia, potentially mediated through gut microbiota-derived bioactive metabolites, such as short-chain fatty acids (SCFAs), secondary bile acids, and their associated signaling pathways, which may be translated into the development of new microbiome-based treatment and diagnostic approaches. Furthermore, we identify challenges that need addressing in future studies to facilitate the translation into potential novel treatment and differential diagnosis for older individuals with sarcopenia.…”
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A Rare Stapes Abnormality by Hala Kanona, Jagdeep Singh Virk, Gaurav Kumar, Sanjiv Chawda, Sherif Khalil

“…The aim of this study is to increase awareness of rare presentations, diagnostic difficulties alongside management of conductive hearing loss and ossicular abnormalities. …”
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